{"id":"https://openalex.org/W2109724643","doi":"https://doi.org/10.1046/j.1468-2982.1983.0304207.x","title":"Prophylactic Treatment of Classical and Non-Classical Migraine With Metoprolol\u2014a Comparison with Placebo","display_name":"Prophylactic Treatment of Classical and Non-Classical Migraine With Metoprolol\u2014a Comparison with Placebo","publication_year":1983,"publication_date":"1983-12-01","ids":{"openalex":"https://openalex.org/W2109724643","doi":"https://doi.org/10.1046/j.1468-2982.1983.0304207.x","mag":"2109724643","pmid":"https://pubmed.ncbi.nlm.nih.gov/6640652"},"language":"en","primary_location":{"id":"doi:10.1046/j.1468-2982.1983.0304207.x","doi":"https://doi.org/10.1046/j.1468-2982.1983.0304207.x","is_oa":false,"landing_page_url":"https://doi.org/10.1046/j.1468-2982.1983.0304207.x","pdf_url":null,"source":{"id":"https://openalex.org/S141866484","display_name":"Cephalalgia","issn_l":"0333-1024","issn":["0333-1024","1468-2982"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cephalalgia","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5091223950","display_name":"P. G. Andersson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I204337017","display_name":"Aarhus University","ror":"https://ror.org/01aj84f44","country_code":"DK","type":"education","lineage":["https://openalex.org/I204337017"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"P. G. Andersson","raw_affiliation_strings":["P. G. Andersson, Hovedgaden 63, DK-8220 Brabrand, Denmark; S. Dahl and P. E. Hansen, Department of Neurology, S\u00f8nderborg Hospital, S\u00f8nderborg, Denmark; J. H. Hansen, T. Nygaard Kristensen & B. de Fine Olivarius, Department of Neurology, University of Aarhus, Aarhus, Denmark; C. Hedman, Medical Department, AB H\u00e4ssle, M\u00f6lndal, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"P. G. Andersson, Hovedgaden 63, DK-8220 Brabrand, Denmark; S. Dahl and P. E. Hansen, Department of Neurology, S\u00f8nderborg Hospital, S\u00f8nderborg, Denmark; J. H. Hansen, T. Nygaard Kristensen & B. de Fine Olivarius, Department of Neurology, University of Aarhus, Aarhus, Denmark; C. Hedman, Medical Department, AB H\u00e4ssle, M\u00f6lndal, Sweden","institution_ids":["https://openalex.org/I204337017"]}]},{"author_position":"middle","author":{"id":null,"display_name":"S. Dahl","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I204337017","display_name":"Aarhus University","ror":"https://ror.org/01aj84f44","country_code":"DK","type":"education","lineage":["https://openalex.org/I204337017"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"S. Dahl","raw_affiliation_strings":["P. G. Andersson, Hovedgaden 63, DK-8220 Brabrand, Denmark; S. Dahl and P. E. Hansen, Department of Neurology, S\u00f8nderborg Hospital, S\u00f8nderborg, Denmark; J. H. Hansen, T. Nygaard Kristensen & B. de Fine Olivarius, Department of Neurology, University of Aarhus, Aarhus, Denmark; C. Hedman, Medical Department, AB H\u00e4ssle, M\u00f6lndal, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"P. G. Andersson, Hovedgaden 63, DK-8220 Brabrand, Denmark; S. Dahl and P. E. Hansen, Department of Neurology, S\u00f8nderborg Hospital, S\u00f8nderborg, Denmark; J. H. Hansen, T. Nygaard Kristensen & B. de Fine Olivarius, Department of Neurology, University of Aarhus, Aarhus, Denmark; C. Hedman, Medical Department, AB H\u00e4ssle, M\u00f6lndal, Sweden","institution_ids":["https://openalex.org/I204337017"]}]},{"author_position":"middle","author":{"id":null,"display_name":"J. H. Hansen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I204337017","display_name":"Aarhus University","ror":"https://ror.org/01aj84f44","country_code":"DK","type":"education","lineage":["https://openalex.org/I204337017"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"J. H. Hansen","raw_affiliation_strings":["P. G. Andersson, Hovedgaden 63, DK-8220 Brabrand, Denmark; S. Dahl and P. E. Hansen, Department of Neurology, S\u00f8nderborg Hospital, S\u00f8nderborg, Denmark; J. H. Hansen, T. Nygaard Kristensen & B. de Fine Olivarius, Department of Neurology, University of Aarhus, Aarhus, Denmark; C. Hedman, Medical Department, AB H\u00e4ssle, M\u00f6lndal, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"P. G. Andersson, Hovedgaden 63, DK-8220 Brabrand, Denmark; S. Dahl and P. E. Hansen, Department of Neurology, S\u00f8nderborg Hospital, S\u00f8nderborg, Denmark; J. H. Hansen, T. Nygaard Kristensen & B. de Fine Olivarius, Department of Neurology, University of Aarhus, Aarhus, Denmark; C. Hedman, Medical Department, AB H\u00e4ssle, M\u00f6lndal, Sweden","institution_ids":["https://openalex.org/I204337017"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077576241","display_name":"Per Evald Hansen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I204337017","display_name":"Aarhus University","ror":"https://ror.org/01aj84f44","country_code":"DK","type":"education","lineage":["https://openalex.org/I204337017"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"P. E. Hansen","raw_affiliation_strings":["P. G. Andersson, Hovedgaden 63, DK-8220 Brabrand, Denmark; S. Dahl and P. E. Hansen, Department of Neurology, S\u00f8nderborg Hospital, S\u00f8nderborg, Denmark; J. H. Hansen, T. Nygaard Kristensen & B. de Fine Olivarius, Department of Neurology, University of Aarhus, Aarhus, Denmark; C. Hedman, Medical Department, AB H\u00e4ssle, M\u00f6lndal, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"P. G. Andersson, Hovedgaden 63, DK-8220 Brabrand, Denmark; S. Dahl and P. E. Hansen, Department of Neurology, S\u00f8nderborg Hospital, S\u00f8nderborg, Denmark; J. H. Hansen, T. Nygaard Kristensen & B. de Fine Olivarius, Department of Neurology, University of Aarhus, Aarhus, Denmark; C. Hedman, Medical Department, AB H\u00e4ssle, M\u00f6lndal, Sweden","institution_ids":["https://openalex.org/I204337017"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109776956","display_name":"C. Hedman","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I204337017","display_name":"Aarhus University","ror":"https://ror.org/01aj84f44","country_code":"DK","type":"education","lineage":["https://openalex.org/I204337017"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"C. Hedman","raw_affiliation_strings":["P. G. Andersson, Hovedgaden 63, DK-8220 Brabrand, Denmark; S. Dahl and P. E. Hansen, Department of Neurology, S\u00f8nderborg Hospital, S\u00f8nderborg, Denmark; J. H. Hansen, T. Nygaard Kristensen & B. de Fine Olivarius, Department of Neurology, University of Aarhus, Aarhus, Denmark; C. Hedman, Medical Department, AB H\u00e4ssle, M\u00f6lndal, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"P. G. Andersson, Hovedgaden 63, DK-8220 Brabrand, Denmark; S. Dahl and P. E. Hansen, Department of Neurology, S\u00f8nderborg Hospital, S\u00f8nderborg, Denmark; J. H. Hansen, T. Nygaard Kristensen & B. de Fine Olivarius, Department of Neurology, University of Aarhus, Aarhus, Denmark; C. Hedman, Medical Department, AB H\u00e4ssle, M\u00f6lndal, Sweden","institution_ids":["https://openalex.org/I204337017"]}]},{"author_position":"middle","author":{"id":null,"display_name":"T. Nygaard Kristensen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I204337017","display_name":"Aarhus University","ror":"https://ror.org/01aj84f44","country_code":"DK","type":"education","lineage":["https://openalex.org/I204337017"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"T. Nygaard Kristensen","raw_affiliation_strings":["P. G. Andersson, Hovedgaden 63, DK-8220 Brabrand, Denmark; S. Dahl and P. E. Hansen, Department of Neurology, S\u00f8nderborg Hospital, S\u00f8nderborg, Denmark; J. H. Hansen, T. Nygaard Kristensen & B. de Fine Olivarius, Department of Neurology, University of Aarhus, Aarhus, Denmark; C. Hedman, Medical Department, AB H\u00e4ssle, M\u00f6lndal, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"P. G. Andersson, Hovedgaden 63, DK-8220 Brabrand, Denmark; S. Dahl and P. E. Hansen, Department of Neurology, S\u00f8nderborg Hospital, S\u00f8nderborg, Denmark; J. H. Hansen, T. Nygaard Kristensen & B. de Fine Olivarius, Department of Neurology, University of Aarhus, Aarhus, Denmark; C. Hedman, Medical Department, AB H\u00e4ssle, M\u00f6lndal, Sweden","institution_ids":["https://openalex.org/I204337017"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5109114685","display_name":"Bent de Fine Olivarius","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I204337017","display_name":"Aarhus University","ror":"https://ror.org/01aj84f44","country_code":"DK","type":"education","lineage":["https://openalex.org/I204337017"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"B. de Fine Olivarius","raw_affiliation_strings":["P. G. Andersson, Hovedgaden 63, DK-8220 Brabrand, Denmark; S. Dahl and P. E. Hansen, Department of Neurology, S\u00f8nderborg Hospital, S\u00f8nderborg, Denmark; J. H. Hansen, T. Nygaard Kristensen & B. de Fine Olivarius, Department of Neurology, University of Aarhus, Aarhus, Denmark; C. Hedman, Medical Department, AB H\u00e4ssle, M\u00f6lndal, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"P. G. Andersson, Hovedgaden 63, DK-8220 Brabrand, Denmark; S. Dahl and P. E. Hansen, Department of Neurology, S\u00f8nderborg Hospital, S\u00f8nderborg, Denmark; J. H. Hansen, T. Nygaard Kristensen & B. de Fine Olivarius, Department of Neurology, University of Aarhus, Aarhus, Denmark; C. Hedman, Medical Department, AB H\u00e4ssle, M\u00f6lndal, Sweden","institution_ids":["https://openalex.org/I204337017"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I204337017"],"apc_list":{"value":3000,"currency":"USD","value_usd":3000},"apc_paid":null,"fwci":3.1204,"has_fulltext":false,"cited_by_count":66,"citation_normalized_percentile":{"value":0.91764831,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":87,"max":97},"biblio":{"volume":"3","issue":"4","first_page":"207","last_page":"212"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10498","display_name":"Migraine and Headache Studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10498","display_name":"Migraine and Headache Studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10852","display_name":"Temporomandibular Joint Disorders","score":0.0,"subfield":{"id":"https://openalex.org/subfields/3504","display_name":"Oral Surgery"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10420","display_name":"Intracranial Aneurysms: Treatment and Complications","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/metoprolol","display_name":"metoprolol","score":0.9049999713897705},{"id":"https://openalex.org/keywords/migraine-prevention","display_name":"migraine prophylaxis","score":0.8640000224113464},{"id":"https://openalex.org/keywords/classical-migraine","display_name":"classical migraine","score":0.8169999718666077},{"id":"https://openalex.org/keywords/beta-blockers","display_name":"beta-blockers","score":0.777999997138977},{"id":"https://openalex.org/keywords/headache-frequency","display_name":"headache frequency","score":0.7459999918937683},{"id":"https://openalex.org/keywords/headache-intensity","display_name":"headache severity","score":0.8149999976158142},{"id":"https://openalex.org/keywords/analgesic-use","display_name":"analgesic use","score":0.8429999947547913},{"id":"https://openalex.org/keywords/controlled-release-formulation","display_name":"controlled-release formulation","score":0.6869999766349792},{"id":"https://openalex.org/keywords/drug-tolerability","display_name":"drug tolerability","score":0.7720000147819519}],"concepts":[{"id":"https://openalex.org/C2781280847","wikidata":"https://www.wikidata.org/wiki/Q409468","display_name":"Metoprolol","level":2,"score":0.9653893709182739},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8973362445831299},{"id":"https://openalex.org/C2778541695","wikidata":"https://www.wikidata.org/wiki/Q133823","display_name":"Migraine","level":2,"score":0.8338159918785095},{"id":"https://openalex.org/C27081682","wikidata":"https://www.wikidata.org/wiki/Q269829","display_name":"Placebo","level":3,"score":0.8160943984985352},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.52135169506073},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.34263619780540466},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004311","descriptor_name":"Double-Blind Method","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008790","descriptor_name":"Metoprolol","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008881","descriptor_name":"Migraine Disorders","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D010919","descriptor_name":"Placebos","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1046/j.1468-2982.1983.0304207.x","doi":"https://doi.org/10.1046/j.1468-2982.1983.0304207.x","is_oa":false,"landing_page_url":"https://doi.org/10.1046/j.1468-2982.1983.0304207.x","pdf_url":null,"source":{"id":"https://openalex.org/S141866484","display_name":"Cephalalgia","issn_l":"0333-1024","issn":["0333-1024","1468-2982"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cephalalgia","raw_type":"journal-article"},{"id":"pmid:6640652","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/6640652","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cephalalgia : an international journal of headache","raw_type":"Comparative Study"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.821.3823","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.821.3823","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://cep.sagepub.com/content/3/4/207.full.pdf","raw_type":"text"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":22,"referenced_works":["https://openalex.org/W24957198","https://openalex.org/W1969376401","https://openalex.org/W1972484613","https://openalex.org/W1972912092","https://openalex.org/W1980759529","https://openalex.org/W1996980138","https://openalex.org/W2044430064","https://openalex.org/W2053627186","https://openalex.org/W2070969081","https://openalex.org/W2082760603","https://openalex.org/W2091531513","https://openalex.org/W2096973095","https://openalex.org/W2134860801","https://openalex.org/W2150460142","https://openalex.org/W2152286645","https://openalex.org/W2155614034","https://openalex.org/W2158439101","https://openalex.org/W2165457126","https://openalex.org/W2170481786","https://openalex.org/W2171389560","https://openalex.org/W2418299362","https://openalex.org/W2976458589"],"related_works":["https://openalex.org/W2041541969","https://openalex.org/W2039506024","https://openalex.org/W2084509319","https://openalex.org/W2398252219","https://openalex.org/W7098732900","https://openalex.org/W2106341900","https://openalex.org/W2024438932","https://openalex.org/W2734709360","https://openalex.org/W2052899189","https://openalex.org/W1984090297"],"abstract_inverted_index":{"A":[0],"double-blind":[1],"investigation":[2],"with":[3,49],"parallel":[4],"groups":[5],"was":[6],"carried":[7],"out":[8],"in":[9,25,41,72],"three":[10],"Danish":[11],"neurological":[12],"clinics":[13],"to":[14],"evaluate":[15],"the":[16,34,42,57,65],"effect":[17],"of":[18,45,59,64],"metoprolol":[19,69,91],"(Beloc,":[20],"Betaloc,":[21],"Seloken)":[22],"versus":[23],"placebo":[24,88],"migraine":[26],"patients.":[27],"71":[28],"patients":[29],"were":[30,39],"included;":[31],"62":[32],"completed":[33],"study.":[35],"The":[36,62],"following":[37],"parameters":[38,86],"used":[40],"evaluation:":[43],"frequency":[44],"headache":[46],"attacks,":[47],"days":[48],"migraine,":[50],"severity":[51],"score":[52],"(days":[53],"X":[54],"intensity),":[55],"and":[56,89],"consumption":[58],"pain-relieving":[60],"tablets.":[61],"results":[63],"study":[66],"show":[67],"that":[68,90],"200":[70],"mg":[71],"Durules":[73],"(a":[74],"controlled":[75],"release":[76],"formulation)":[77],"once":[78],"daily":[79],"is":[80,92],"more":[81],"effective":[82],"regarding":[83],"all":[84],"evaluated":[85],"than":[87],"well":[93],"tolerated.":[94]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":3}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}