{"id":"https://openalex.org/W2109681124","doi":null,"title":"Immunological responses in genital HPV infections and etiology of cervical cancer","display_name":"Immunological responses in genital HPV infections and etiology of cervical cancer","publication_year":2005,"publication_date":"2005-05-13","ids":{"openalex":"https://openalex.org/W2109681124","mag":"2109681124"},"language":"en","primary_location":{"id":"pmh:oai:figshare.com:article/26904763","doi":null,"is_oa":false,"landing_page_url":"https://figshare.com/articles/thesis/Immunological_responses_in_genital_HPV_infections_and_etiology_of_cervical_cancer/26904763","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Thesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://hdl.handle.net/10616/39722","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5030046508","display_name":"Lisen Arnheim","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Lisen Arnheim","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5030046508"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10146","display_name":"Cervical Cancer and HPV Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10146","display_name":"Cervical Cancer and HPV Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10428","display_name":"Reproductive tract infections research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10307","display_name":"Head and Neck Cancer Studies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2733","display_name":"Otorhinolaryngology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cervical-cancer","display_name":"cervical cancer","score":0.8989999890327454},{"id":"https://openalex.org/keywords/human-papillomavirus","display_name":"human papillomavirus","score":0.949999988079071},{"id":"https://openalex.org/keywords/hpv-16","display_name":"HPV16","score":0.8410000205039978},{"id":"https://openalex.org/keywords/hpv-18","display_name":"HPV 18","score":0.9959999918937683},{"id":"https://openalex.org/keywords/hpv-6","display_name":"HPV 6","score":0.9279999732971191},{"id":"https://openalex.org/keywords/chlamydia-trachomatis","display_name":"Chlamydia trachomatis","score":0.8289999961853027},{"id":"https://openalex.org/keywords/herpes-simplex-virus-type-2","display_name":"herpes simplex virus type 2","score":0.8999999761581421},{"id":"https://openalex.org/keywords/dna-vaccine","display_name":"DNA vaccine","score":0.6570000052452087},{"id":"https://openalex.org/keywords/virus-like-particles","display_name":"virus-like particles","score":0.9350000023841858},{"id":"https://openalex.org/keywords/cytokines","display_name":"cytokines","score":0.45399999618530273},{"id":"https://openalex.org/keywords/il-10","display_name":"IL-10","score":0.5099999904632568},{"id":"https://openalex.org/keywords/il-12","display_name":"IL-12","score":0.5410000085830688},{"id":"https://openalex.org/keywords/il-15","display_name":"IL-15","score":0.47099998593330383},{"id":"https://openalex.org/keywords/il-17","display_name":"IL-17","score":0.5180000066757202},{"id":"https://openalex.org/keywords/il-23","display_name":"IL-23","score":0.5260000228881836},{"id":"https://openalex.org/keywords/il-27","display_name":"IL-27","score":0.4729999899864197},{"id":"https://openalex.org/keywords/il-28","display_name":"IL-28","score":0.5360000133514404},{"id":"https://openalex.org/keywords/il-29","display_name":"IL-29","score":0.7509999871253967},{"id":"https://openalex.org/keywords/il-31","display_name":"IL-31","score":0.6050000190734863},{"id":"https://openalex.org/keywords/il-32","display_name":"IL-32","score":0.6039999723434448},{"id":"https://openalex.org/keywords/il-33","display_name":"IL-33","score":0.6140000224113464},{"id":"https://openalex.org/keywords/il-34","display_name":"IL-34","score":0.7059999704360962},{"id":"https://openalex.org/keywords/il-35","display_name":"IL-35","score":0.796999990940094},{"id":"https://openalex.org/keywords/il-36","display_name":"IL-36","score":0.8080000281333923},{"id":"https://openalex.org/keywords/il-37","display_name":"IL-37","score":0.8640000224113464},{"id":"https://openalex.org/keywords/il-38","display_name":"IL-38","score":0.890999972820282},{"id":"https://openalex.org/keywords/il-39","display_name":"IL-39","score":0.8140000104904175},{"id":"https://openalex.org/keywords/il-40","display_name":"IL-40","score":0.8579999804496765},{"id":"https://openalex.org/keywords/il-41","display_name":"IL-41","score":0.8500000238418579},{"id":"https://openalex.org/keywords/il-42","display_name":"IL-42","score":0.8679999709129333},{"id":"https://openalex.org/keywords/il-43","display_name":"IL-43","score":0.9169999957084656},{"id":"https://openalex.org/keywords/il-44","display_name":"IL-44","score":0.9459999799728394},{"id":"https://openalex.org/keywords/il-45","display_name":"IL-45","score":0.9039999842643738},{"id":"https://openalex.org/keywords/il-46","display_name":"IL-46","score":0.921999990940094},{"id":"https://openalex.org/keywords/il-47","display_name":"IL-47","score":0.925000011920929},{"id":"https://openalex.org/keywords/il-48","display_name":"IL-48","score":0.906000018119812},{"id":"https://openalex.org/keywords/il","display_name":"IL","score":0.9039999842643738}],"concepts":[{"id":"https://openalex.org/C2778220009","wikidata":"https://www.wikidata.org/wiki/Q160105","display_name":"Cervical cancer","level":3,"score":0.8443219661712646},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6841906905174255},{"id":"https://openalex.org/C2778580637","wikidata":"https://www.wikidata.org/wiki/Q184627","display_name":"HPV infection","level":4,"score":0.6328772902488708},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.6093695759773254},{"id":"https://openalex.org/C2780009117","wikidata":"https://www.wikidata.org/wiki/Q900189","display_name":"HPV vaccines","level":5,"score":0.5813940763473511},{"id":"https://openalex.org/C137627325","wikidata":"https://www.wikidata.org/wiki/Q156318","display_name":"Etiology","level":2,"score":0.5773035883903503},{"id":"https://openalex.org/C555283112","wikidata":"https://www.wikidata.org/wiki/Q1637543","display_name":"Carcinogenesis","level":3,"score":0.5597420334815979},{"id":"https://openalex.org/C2777740455","wikidata":"https://www.wikidata.org/wiki/Q666412","display_name":"Cervix","level":3,"score":0.5479514598846436},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.5087957978248596},{"id":"https://openalex.org/C22070199","wikidata":"https://www.wikidata.org/wiki/Q192995","display_name":"Vaccination","level":2,"score":0.48607662320137024},{"id":"https://openalex.org/C2776270601","wikidata":"https://www.wikidata.org/wiki/Q9055203","display_name":"Papillomaviridae","level":4,"score":0.4474062919616699},{"id":"https://openalex.org/C2780234812","wikidata":"https://www.wikidata.org/wiki/Q1787013","display_name":"Cancer prevention","level":3,"score":0.44388291239738464},{"id":"https://openalex.org/C183021626","wikidata":"https://www.wikidata.org/wiki/Q4620674","display_name":"Sex organ","level":2,"score":0.4418966770172119},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.4322681725025177},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.4300435781478882},{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.3666885197162628},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3421784043312073},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.15475520491600037},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.06613150238990784}],"mesh":[],"locations_count":3,"locations":[{"id":"pmh:oai:figshare.com:article/26904763","doi":null,"is_oa":false,"landing_page_url":"https://figshare.com/articles/thesis/Immunological_responses_in_genital_HPV_infections_and_etiology_of_cervical_cancer/26904763","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Thesis"},{"id":"pmh:oai:openarchive.ki.se:10616/39722","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10616/39722","pdf_url":null,"source":{"id":"https://openalex.org/S4306400147","display_name":"Open Archive (Karolinska Institutet)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I28166907","host_organization_name":"Karolinska Institutet","host_organization_lineage":["https://openalex.org/I28166907"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/doctoralThesis"},{"id":"mag:2109681124","doi":null,"is_oa":false,"landing_page_url":"https://openarchive.ki.se/xmlui/bitstream/10616/39722/1/thesis.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:openarchive.ki.se:10616/39722","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10616/39722","pdf_url":null,"source":{"id":"https://openalex.org/S4306400147","display_name":"Open Archive (Karolinska Institutet)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I28166907","host_organization_name":"Karolinska Institutet","host_organization_lineage":["https://openalex.org/I28166907"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/doctoralThesis"},"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":284,"referenced_works":["https://openalex.org/W14592758","https://openalex.org/W22520275","https://openalex.org/W25341021","https://openalex.org/W147743709","https://openalex.org/W156003141","https://openalex.org/W158094820","https://openalex.org/W186078767","https://openalex.org/W190015672","https://openalex.org/W240876023","https://openalex.org/W575389344","https://openalex.org/W1488481558","https://openalex.org/W1500432626","https://openalex.org/W1501034426","https://openalex.org/W1506952386","https://openalex.org/W1515230631","https://openalex.org/W1555277146","https://openalex.org/W1561111148","https://openalex.org/W1564212979","https://openalex.org/W1578437294","https://openalex.org/W1581360649","https://openalex.org/W1582213503","https://openalex.org/W1583416075","https://openalex.org/W1586954595","https://openalex.org/W1600823853","https://openalex.org/W1607071909","https://openalex.org/W1607774948","https://openalex.org/W1737749102","https://openalex.org/W1828182586","https://openalex.org/W1832907691","https://openalex.org/W1859510236","https://openalex.org/W1860218822","https://openalex.org/W1882571763","https://openalex.org/W1913494533","https://openalex.org/W1921701673","https://openalex.org/W1946102895","https://openalex.org/W1949036755","https://openalex.org/W1966886063","https://openalex.org/W1967254492","https://openalex.org/W1967960141","https://openalex.org/W1968522081","https://openalex.org/W1968735269","https://openalex.org/W1969023474","https://openalex.org/W1969392374","https://openalex.org/W1969676143","https://openalex.org/W1970296166","https://openalex.org/W1970401072","https://openalex.org/W1976051908","https://openalex.org/W1976491544","https://openalex.org/W1976614815","https://openalex.org/W1977223394","https://openalex.org/W1978580498","https://openalex.org/W1982208448","https://openalex.org/W1983494331","https://openalex.org/W1984202369","https://openalex.org/W1984785242","https://openalex.org/W1984850107","https://openalex.org/W1984861740","https://openalex.org/W1987350137","https://openalex.org/W1987958334","https://openalex.org/W1990969017","https://openalex.org/W1991784511","https://openalex.org/W1992693697","https://openalex.org/W1992749561","https://openalex.org/W1993633777","https://openalex.org/W1995090970","https://openalex.org/W1995765989","https://openalex.org/W1995768712","https://openalex.org/W1998897433","https://openalex.org/W2000704250","https://openalex.org/W2001429203","https://openalex.org/W2005126548","https://openalex.org/W2007401297","https://openalex.org/W2007990267","https://openalex.org/W2008748900","https://openalex.org/W2010522597","https://openalex.org/W2012868689","https://openalex.org/W2017352677","https://openalex.org/W2018087970","https://openalex.org/W2018524935","https://openalex.org/W2018646351","https://openalex.org/W2019158358","https://openalex.org/W2019606310","https://openalex.org/W2021438212","https://openalex.org/W2022567169","https://openalex.org/W2022792317","https://openalex.org/W2024575518","https://openalex.org/W2024631433","https://openalex.org/W2026599341","https://openalex.org/W2026712887","https://openalex.org/W2027215225","https://openalex.org/W2027401228","https://openalex.org/W2027801418","https://openalex.org/W2028461988","https://openalex.org/W2030337719","https://openalex.org/W2033405158","https://openalex.org/W2034935809","https://openalex.org/W2035202944","https://openalex.org/W2035338651","https://openalex.org/W2036069120","https://openalex.org/W2037491887","https://openalex.org/W2037787205","https://openalex.org/W2039288030","https://openalex.org/W2039334966","https://openalex.org/W2039382131","https://openalex.org/W2039906679","https://openalex.org/W2040448006","https://openalex.org/W2041703757","https://openalex.org/W2041725513","https://openalex.org/W2042766700","https://openalex.org/W2042801675","https://openalex.org/W2044453012","https://openalex.org/W2050429141","https://openalex.org/W2051041090","https://openalex.org/W2052175020","https://openalex.org/W2052641641","https://openalex.org/W2054643867","https://openalex.org/W2058321555","https://openalex.org/W2059669536","https://openalex.org/W2062581776","https://openalex.org/W2062596080","https://openalex.org/W2063137941","https://openalex.org/W2064353414","https://openalex.org/W2064736391","https://openalex.org/W2065298839","https://openalex.org/W2066029482","https://openalex.org/W2066119742","https://openalex.org/W2066160616","https://openalex.org/W2066458822","https://openalex.org/W2068183346","https://openalex.org/W2069794080","https://openalex.org/W2070152626","https://openalex.org/W2073874737","https://openalex.org/W2074393823","https://openalex.org/W2075873712","https://openalex.org/W2076046458","https://openalex.org/W2076655918","https://openalex.org/W2076694631","https://openalex.org/W2077197239","https://openalex.org/W2077667597","https://openalex.org/W2079128321","https://openalex.org/W2081947880","https://openalex.org/W2085390133","https://openalex.org/W2085813472","https://openalex.org/W2086315880","https://openalex.org/W2087642630","https://openalex.org/W2087659731","https://openalex.org/W2087668871","https://openalex.org/W2087851046","https://openalex.org/W2088077480","https://openalex.org/W2088141935","https://openalex.org/W2088457548","https://openalex.org/W2088517066","https://openalex.org/W2089348790","https://openalex.org/W2090288855","https://openalex.org/W2091797425","https://openalex.org/W2091844322","https://openalex.org/W2094529863","https://openalex.org/W2095186887","https://openalex.org/W2095976339","https://openalex.org/W2096360080","https://openalex.org/W2096801163","https://openalex.org/W2097796128","https://openalex.org/W2097889231","https://openalex.org/W2098318463","https://openalex.org/W2098765233","https://openalex.org/W2098925859","https://openalex.org/W2099660384","https://openalex.org/W2099673604","https://openalex.org/W2101631372","https://openalex.org/W2102667641","https://openalex.org/W2102796726","https://openalex.org/W2102925847","https://openalex.org/W2103234666","https://openalex.org/W2104039084","https://openalex.org/W2105018146","https://openalex.org/W2107749930","https://openalex.org/W2109737091","https://openalex.org/W2110404633","https://openalex.org/W2112011162","https://openalex.org/W2112859230","https://openalex.org/W2113395588","https://openalex.org/W2113590402","https://openalex.org/W2113795033","https://openalex.org/W2115042566","https://openalex.org/W2117213405","https://openalex.org/W2117771134","https://openalex.org/W2117796958","https://openalex.org/W2118110504","https://openalex.org/W2118479729","https://openalex.org/W2119315370","https://openalex.org/W2120655585","https://openalex.org/W2120783955","https://openalex.org/W2121500849","https://openalex.org/W2121578469","https://openalex.org/W2121819501","https://openalex.org/W2122670984","https://openalex.org/W2123853921","https://openalex.org/W2124370773","https://openalex.org/W2125748368","https://openalex.org/W2128681927","https://openalex.org/W2129057663","https://openalex.org/W2129317658","https://openalex.org/W2130530238","https://openalex.org/W2130619064","https://openalex.org/W2131053210","https://openalex.org/W2131199391","https://openalex.org/W2131255017","https://openalex.org/W2131382865","https://openalex.org/W2132268212","https://openalex.org/W2133765716","https://openalex.org/W2133818906","https://openalex.org/W2135781277","https://openalex.org/W2136111158","https://openalex.org/W2136484078","https://openalex.org/W2138004014","https://openalex.org/W2138786372","https://openalex.org/W2138865332","https://openalex.org/W2140355674","https://openalex.org/W2141005744","https://openalex.org/W2141029872","https://openalex.org/W2141143434","https://openalex.org/W2141196337","https://openalex.org/W2141701486","https://openalex.org/W2141937928","https://openalex.org/W2142116340","https://openalex.org/W2142294288","https://openalex.org/W2144005905","https://openalex.org/W2147235018","https://openalex.org/W2147624625","https://openalex.org/W2148643959","https://openalex.org/W2148870453","https://openalex.org/W2149028561","https://openalex.org/W2149397805","https://openalex.org/W2150021883","https://openalex.org/W2150436558","https://openalex.org/W2151372715","https://openalex.org/W2152156910","https://openalex.org/W2152959169","https://openalex.org/W2153455757","https://openalex.org/W2153462183","https://openalex.org/W2154262967","https://openalex.org/W2154729023","https://openalex.org/W2155313041","https://openalex.org/W2156343698","https://openalex.org/W2156619604","https://openalex.org/W2157490198","https://openalex.org/W2158143653","https://openalex.org/W2160874245","https://openalex.org/W2161027033","https://openalex.org/W2162088345","https://openalex.org/W2162443624","https://openalex.org/W2163058108","https://openalex.org/W2164313336","https://openalex.org/W2165204343","https://openalex.org/W2165253141","https://openalex.org/W2165681129","https://openalex.org/W2166173416","https://openalex.org/W2168495423","https://openalex.org/W2169027433","https://openalex.org/W2169767104","https://openalex.org/W2169918603","https://openalex.org/W2171670537","https://openalex.org/W2171783306","https://openalex.org/W2176331149","https://openalex.org/W2181538030","https://openalex.org/W2188131794","https://openalex.org/W2208609395","https://openalex.org/W2267930119","https://openalex.org/W2277447145","https://openalex.org/W2300464682","https://openalex.org/W2312876393","https://openalex.org/W2330826514","https://openalex.org/W2331157589","https://openalex.org/W2342166036","https://openalex.org/W2397442976","https://openalex.org/W2409818489","https://openalex.org/W2410139823","https://openalex.org/W2417680486","https://openalex.org/W2419316480","https://openalex.org/W2421395535","https://openalex.org/W2430438384","https://openalex.org/W2468531558","https://openalex.org/W3143771051","https://openalex.org/W3159004246"],"related_works":["https://openalex.org/W4300662935","https://openalex.org/W1968641189","https://openalex.org/W1499838554","https://openalex.org/W4388946839","https://openalex.org/W1958269310","https://openalex.org/W2119050578","https://openalex.org/W4240236713","https://openalex.org/W1582213503","https://openalex.org/W6991637158","https://openalex.org/W2094666432"],"abstract_inverted_index":{"Cervical":[0],"cancer":[1,40,47,110,202,252,309,491],"is":[2,87,180,342,428,440],"one":[3],"of":[4,9,39,41,45,65,71,76,80,94,104,118,124,157,193,198,201,217,295,299,307,315,323,397,410,460,489,544,551,554,590,675],"the":[5,35,42,77,81,102,305,321,331,395,533,639],"most":[6],"common":[7],"forms":[8],"cancers":[10],"in":[11,85,108,221,234,253,304,338,390,403,406,436,475,651,680],"women.":[12],"Every":[13],"year":[14],"approximately":[15],"450,000":[16],"women":[17,96,219,414,452,465,473,652],"are":[18,32,60,73,210,505],"diagnosed":[19],"worldwide":[20],"and":[21,67,122,144,155,160,165,171,178,188,203,213,264,281,285,302,310,383,401,438,512,647,655,678],"200,000":[22],"die.":[23],"The":[24,227,270,291,451],"sexually":[25,142],"transmitted":[26,143],"oncogenic":[27],"human":[28,657],"papillomavirus":[29,658],"(HPV)":[30],"types":[31,64,84],"established":[33,115],"as":[34,147,149],"major":[36,334],"etiological":[37,297],"agents":[38,146,162],"cervix.":[43],"Eradication":[44],"cervical":[46,109,166,206,251,308,404,490,683],"by":[48],"vaccination":[49,357],"against":[50,163,277,330,387],"HPV":[51,66,83,107,137,164,176,194,232,278,300,332,346,388,424],"has":[52,184,230],"therefore":[53],"become":[54],"a":[55,91,235,254,312,324,373,407,422,429,441,476,516],"promising":[56],"approach.":[57],"However,":[58],"there":[59],"more":[61],"than":[62,537],"100":[63],"at":[68],"least":[69],"10":[70],"these":[72,362],"oncogenic.":[74],"Knowledge":[75],"quantitative":[78],"importance":[79],"different":[82,119],"carcinogenesis":[86,179],"needed.":[88],"As":[89],"only":[90],"small":[92],"fraction":[93],"ever-infected":[95],"go":[97],"on":[98,416,493,507],"to":[99,106,113,245,327,369,464,682],"develop":[100,486],"cancer,":[101,167],"role":[103,298,314],"co-factors":[105,131,174],"also":[111],"needs":[112],"be":[114,349],"for":[116,127,191,196,204,249,275,361,448,497],"evaluation":[117,156],"preventive":[120],"actions":[121],"validation":[123],"intermediate":[125],"endpoints":[126],"such":[128,135],"interventions.":[129],"Many":[130],"have":[132,365],"been":[133],"suggested":[134],"as:":[136],"immune":[138,385,434,445,630],"response":[139],"determinants,":[140],"other":[141],"environmental":[145],"well":[148,343],"susceptibility":[150],"genes.":[151,503],"For":[152],"development,":[153],"implementation":[154],"both":[158,380,461],"prophylactic":[159],"therapeutic":[161],"knowledge":[168],"about":[169],"HPV-immunity":[170],"how":[172],"various":[173,433],"influence":[175],"persistence":[177],"required.":[181],"This":[182],"thesis":[183],"investigated":[185,320],"immunological":[186],"responses":[187,386],"risk":[189,247,550],"factors":[190,248],"control":[192],"infection,":[195],"development":[197,306],"precursor":[199,487],"stages":[200,488],"invasive":[205,250],"cancer.":[207,592],"Three":[208],"studies":[209,216],"molecular":[211],"epidemiological":[212],"longitudinal":[214],"cohort":[215,408,479,673],"healthy":[218,529],"participating":[220,474],"biobank":[222,478],"cohorts":[223],"or":[224,421,483],"clinical":[225],"trials.":[226],"fourth":[228],"study":[229,246,292,409,674],"analysed":[231,274],"immunity":[233,329],"mouse":[236],"model.":[237],"In":[238,258,470],"paper":[239,471],"I,":[240],"Nordic":[241],"serumbanks":[242],"were":[243,268,273,467,495,541],"used":[244],"nested":[255],"case-control":[256],"study.":[257],"total,":[259],"543":[260],"prospectively":[261],"occurring":[262],"cases":[263],"2675":[265],"matched":[266],"controls,":[267],"identified.":[269,542],"scrum":[271],"samples":[272],"antibodies":[276,382],"6,":[279],"16":[280,301,333,389,425,660],"18,":[282],"Chlamydia":[283,316],"trachomatis":[284],"Herpes":[286],"simplex":[287],"virus":[288],"type":[289,659],"2.":[290],"found":[293],"evidence":[294],"an":[296,520],"18":[303],"suggests":[311],"cofactor":[313],"trachomatis.":[317],"Paper":[318,392],"II":[319],"ability":[322],"DNA":[325,359,412],"vaccine":[326],"induce":[328,379,628],"capsid":[335],"protein":[336],"L1":[337,376,621],"mice.":[339,391],"Although,":[340],"it":[341],"known":[344],"that":[345,431,443],"infection":[347,456],"can":[348,514],"prevented":[350],"with":[351,358,372,548,623,653],"so":[352,524],"called":[353],"virus-like":[354],"particles":[355,363],"(VLPs),":[356],"coding":[360],"could":[364],"practical":[366],"advantages":[367],"compared":[368,463],"VLPs.":[370],"Vaccination":[371],"modified":[374],"HPV16":[375,411],"plasmid":[377],"did":[378,482,484],"neutralising":[381],"cell-mediated":[384],"III":[393],"studied":[394],"concentrations":[396],"two":[398],"cytokines":[399,462],"(CXCL8":[400],"IFN-gamma)":[402],"secretions":[405],"positive":[413],"who":[415,453,466,480],"follow-up":[417,494],"either":[418,481],"had":[419,457],"clearance":[420],"persistent":[423,654],"infection.":[426,661],"CXCL8":[427,646],"chemokine":[430],"attracts":[432],"cells":[435,446,511,526,530],"inflammation":[437],"IFN-gamma":[439],"cytokine":[442],"activates":[444],"important":[447],"viral":[449],"clearance.":[450],"cleared":[454,656],"their":[455],"higher":[458],"levels":[459,650],"persistently":[468],"infected.":[469],"IV,":[472],"population-based":[477,672],"not":[485],"(CIN)":[492],"screened":[496],"14":[498],"killer":[499,509],"immunoglobulin-like":[500],"receptor":[501],"(KIR)":[502],"KIRs":[504],"expressed":[506],"natural":[508],"(NK)":[510],"they":[513],"distinguish":[515],"normal":[517],"cell":[518],"from":[519],"abnormal.":[521],"By":[522],"doing":[523],"NK":[525],"win":[527],"spare":[528],"while":[531],"killing":[532],"abnormal":[534],"cell.":[535],"More":[536],"70":[538],"KIR":[539,676],"genotypes":[540,679],"One":[543],"which":[545],"was":[546],"associated":[547],"increased":[549],"CIN.":[552],"List":[553],"scientific":[555],"papers":[556],"I.":[557],"Arnheim":[558,597,637,664],"L,":[559,569,598,638,665],"Luostarinen":[560],"T,":[561],"Olsson":[562],"K,":[563,577],"Thoresen":[564],"S,":[565],"Ogmundsdottir":[566],"H,":[567,604],"Tryggvadottir":[568],"Wiklund":[570],"F,":[571],"Skare":[572],"GB,":[573],"Eklund":[574],"C,":[575],"Sjolin":[576],"Jellum":[578],"E,":[579,596],"Koskela":[580],"P,":[581],"Wadell":[582],"G,":[583],"Lehtinen":[584],"M,":[585],"Dillner":[586,607,643,666],"J":[587,644],"(2005).":[588,645,670],"Etiology":[589],"cervival":[591],"[Manuscript]":[593],"II.":[594],"Rollman":[595],"Collier":[599],"B,":[600,616],"Oberg":[601],"D,":[602],"Hall":[603],"Klingstrom":[605],"J,":[606,608,614,667],"Pastrana":[609],"DV,":[610],"Buck":[611],"CB,":[612],"Hinkula":[613],"Wahren":[615],"Schwartz":[617],"S":[618],"(2004).":[619],"HPV-16":[620],"genes":[622,677],"inactivated":[624],"negative":[625],"RNA":[626],"elements":[627],"potent":[629],"responses.":[631],"Virology.":[632],"322(1):":[633],"182-9.":[634],"https://pubmed.ncbi.nlm.nih.gov/15063127":[635],"III.":[636],"Swedescreen":[640],"Steering":[641],"Group,":[642],"INF-gamma":[648],"concentration":[649],"[Submitted]":[662],"IV.":[663],"Sanjeevi":[668],"CB":[669],"A":[671],"relation":[681],"intraepithelial":[684],"neoplasia.":[685],"Tissue":[686],"Antigens.":[687],"65(3):":[688],"252-9.":[689],"https://pubmed.ncbi.nlm.nih.gov/15730517":[690]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}
