{"id":"https://openalex.org/W2109095052","doi":null,"title":"Sex-dependent changes in cerebellar thyroid hormone-dependent gene expression following perinatal exposure to thimerosal in rats.","display_name":"Sex-dependent changes in cerebellar thyroid hormone-dependent gene expression following perinatal exposure to thimerosal in rats.","publication_year":2012,"publication_date":"2012-06-01","ids":{"openalex":"https://openalex.org/W2109095052","mag":"2109095052","pmid":"https://pubmed.ncbi.nlm.nih.gov/22791642"},"language":"en","primary_location":{"id":"pmid:22791642","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22791642","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of physiology and pharmacology : an official journal of the Polish Physiological Society","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5017390306","display_name":"Anzalee Khan","orcid":"https://orcid.org/0000-0002-8683-2320","observed_orcids":["https://orcid.org/0000-0002-8683-2320"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"A Khan","raw_affiliation_strings":["Department of Psychiatry, Harvard Medical School/BWH, Boston, MA 02115, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, Harvard Medical School/BWH, Boston, MA 02115, USA","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080281851","display_name":"Zachary L. Sulkowski","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Z L Sulkowski","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061417025","display_name":"T Chen","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"T Chen","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058240948","display_name":"Ann Marie Zavacki","orcid":"https://orcid.org/0000-0001-5103-0937","observed_orcids":["https://orcid.org/0000-0001-5103-0937"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A M Zavacki","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5065209468","display_name":"Elizabeth M. Sajdel","orcid":"https://orcid.org/0000-0001-5821-2493","observed_orcids":["https://orcid.org/0000-0001-5821-2493"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"E M Sajdel-Sulkowska","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.0016,"has_fulltext":false,"cited_by_count":17,"citation_normalized_percentile":{"value":0.70380018,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"63","issue":"3","first_page":"277","last_page":"83"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10819","display_name":"Mercury impact and mitigation studies","score":0.38449999690055847,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10819","display_name":"Mercury impact and mitigation studies","score":0.38449999690055847,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10790","display_name":"Heavy Metal Exposure and Toxicity","score":0.22089999914169312,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10293","display_name":"Thyroid Disorders and Treatments","score":0.15520000457763672,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/thimerosal","display_name":"thimerosal","score":0.996999979019165},{"id":"https://openalex.org/keywords/ethylmercury","display_name":"ethylmercury","score":0.7760000228881836},{"id":"https://openalex.org/keywords/cerebellar-development","display_name":"cerebellar development","score":0.890999972820282},{"id":"https://openalex.org/keywords/thyroid-hormones","display_name":"thyroid hormones","score":0.6710000038146973},{"id":"https://openalex.org/keywords/sex-differences","display_name":"sex differences","score":0.7710000276565552},{"id":"https://openalex.org/keywords/deiodinase-2","display_name":"deiodinase 2","score":0.8050000071525574},{"id":"https://openalex.org/keywords/foxp4","display_name":"FOXP4","score":0.9940000176429749},{"id":"https://openalex.org/keywords/gene-expression","display_name":"gene expression","score":0.39500001072883606},{"id":"https://openalex.org/keywords/neonatal-rats","display_name":"neonatal rats","score":0.4729999899864197}],"concepts":[{"id":"https://openalex.org/C2778063154","wikidata":"https://www.wikidata.org/wiki/Q13561329","display_name":"Reelin","level":3,"score":0.7510340213775635},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.749107837677002},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.7397080659866333},{"id":"https://openalex.org/C171269688","wikidata":"https://www.wikidata.org/wiki/Q17914005","display_name":"DIO2","level":5,"score":0.6805828213691711},{"id":"https://openalex.org/C2778417266","wikidata":"https://www.wikidata.org/wiki/Q24781273","display_name":"Deiodinase","level":4,"score":0.657606303691864},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5831831693649292},{"id":"https://openalex.org/C2779652256","wikidata":"https://www.wikidata.org/wiki/Q130983","display_name":"Cerebellum","level":2,"score":0.5672267079353333},{"id":"https://openalex.org/C188209991","wikidata":"https://www.wikidata.org/wiki/Q14916487","display_name":"DAB1","level":4,"score":0.49401313066482544},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.4852457046508789},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.43368351459503174},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.3466918468475342},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.15220233798027039},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.1303895115852356},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.12674599885940552},{"id":"https://openalex.org/C2779571634","wikidata":"https://www.wikidata.org/wiki/Q422106","display_name":"Thyroid hormones","level":3,"score":0.10994276404380798}],"mesh":[{"descriptor_ui":"D000091042","descriptor_name":"Reelin Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000831","descriptor_name":"Animals, Newborn","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D000831","descriptor_name":"Animals, Newborn","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":false},{"descriptor_ui":"D000831","descriptor_name":"Animals, Newborn","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002454","descriptor_name":"Cell Differentiation","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D002454","descriptor_name":"Cell Differentiation","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002531","descriptor_name":"Cerebellum","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D002531","descriptor_name":"Cerebellum","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":true},{"descriptor_ui":"D002531","descriptor_name":"Cerebellum","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006360","descriptor_name":"Heat-Shock Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D006360","descriptor_name":"Heat-Shock Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D007453","descriptor_name":"Iodide Peroxidase","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D007453","descriptor_name":"Iodide Peroxidase","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009419","descriptor_name":"Nerve Tissue Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009419","descriptor_name":"Nerve Tissue Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011228","descriptor_name":"Prealbumin","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D011228","descriptor_name":"Prealbumin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011918","descriptor_name":"Rats, Inbred SHR","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D011918","descriptor_name":"Rats, Inbred SHR","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012697","descriptor_name":"Serine Endopeptidases","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012697","descriptor_name":"Serine Endopeptidases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012737","descriptor_name":"Sex Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013849","descriptor_name":"Thimerosal","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D013963","descriptor_name":"Thyroid Hormones","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D013963","descriptor_name":"Thyroid Hormones","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D015816","descriptor_name":"Cell Adhesion Molecules, Neuronal","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D015816","descriptor_name":"Cell Adhesion Molecules, Neuronal","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D016326","descriptor_name":"Extracellular Matrix Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D016326","descriptor_name":"Extracellular Matrix Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D018507","descriptor_name":"Gene Expression Regulation, Developmental","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D018507","descriptor_name":"Gene Expression Regulation, Developmental","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D019208","descriptor_name":"Brain-Derived Neurotrophic Factor","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D019208","descriptor_name":"Brain-Derived Neurotrophic Factor","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D049109","descriptor_name":"Cell Proliferation","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051858","descriptor_name":"Forkhead Transcription Factors","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D051858","descriptor_name":"Forkhead Transcription Factors","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:22791642","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22791642","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of physiology and pharmacology : an official journal of the Polish Physiological Society","raw_type":"Journal Article"},{"id":"mag:2109095052","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22791642","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9537000060081482,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1999216385","display_name":"Role of Deiodinases in Thyroid Hormone Homeostasis","funder_award_id":"R01DK076117","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"}],"funders":[{"id":"https://openalex.org/F4320337357","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":49,"referenced_works":["https://openalex.org/W1535627121","https://openalex.org/W1538986452","https://openalex.org/W1757429883","https://openalex.org/W1888485870","https://openalex.org/W1965462646","https://openalex.org/W1967292065","https://openalex.org/W1969635747","https://openalex.org/W1977755850","https://openalex.org/W1979082012","https://openalex.org/W1991454487","https://openalex.org/W2003093916","https://openalex.org/W2004578012","https://openalex.org/W2005453469","https://openalex.org/W2007444979","https://openalex.org/W2022316181","https://openalex.org/W2024116370","https://openalex.org/W2025660828","https://openalex.org/W2027006026","https://openalex.org/W2039996156","https://openalex.org/W2043051914","https://openalex.org/W2045153165","https://openalex.org/W2048338194","https://openalex.org/W2053451079","https://openalex.org/W2060469666","https://openalex.org/W2071628239","https://openalex.org/W2074737091","https://openalex.org/W2079635977","https://openalex.org/W2080345761","https://openalex.org/W2082068065","https://openalex.org/W2087316765","https://openalex.org/W2090755454","https://openalex.org/W2094705166","https://openalex.org/W2097440306","https://openalex.org/W2100049277","https://openalex.org/W2100963942","https://openalex.org/W2103327215","https://openalex.org/W2108528265","https://openalex.org/W2109166550","https://openalex.org/W2119375540","https://openalex.org/W2120695555","https://openalex.org/W2125767999","https://openalex.org/W2129231732","https://openalex.org/W2134088575","https://openalex.org/W2134328303","https://openalex.org/W2148124818","https://openalex.org/W2171204655","https://openalex.org/W2259685795","https://openalex.org/W2361913679","https://openalex.org/W2409405294"],"related_works":["https://openalex.org/W1967292065","https://openalex.org/W1991906891","https://openalex.org/W2091946313","https://openalex.org/W3021569638","https://openalex.org/W2908112539","https://openalex.org/W2090942924","https://openalex.org/W2011450887","https://openalex.org/W2103289239","https://openalex.org/W2103327215","https://openalex.org/W2162067251"],"abstract_inverted_index":{"Mammalian":[0],"brain":[1,51,195,298],"development":[2,103],"is":[3,37,215],"regulated":[4,133,149,290],"by":[5,134,286,291,302],"the":[6,20,33,122,236,258,271,281,313],"action":[7,310],"of":[8,67,77,127,176,212,224,238,246,253,274,296,309],"thyroid":[9],"hormone":[10],"(TH)":[11],"on":[12,32,62,73,231],"target":[13],"genes.":[14],"We":[15,54,118,241],"have":[16,55,242],"previously":[17,243],"shown":[18],"that":[19,91,125,283],"perinatal":[21,83],"exposure":[22,85],"to":[23,27,58,71,87,114,116,217],"thimerosal":[24],"(TM,":[25],"metabolized":[26],"ethylmercury)":[28],"exerts":[29],"neurotoxic":[30],"effects":[31,230],"developing":[34,314],"cerebellum":[35],"and":[36,86,106,112,158,200,220,278,304],"associated":[38],"with":[39],"a":[40,130,166,181,306],"decrease":[41],"in":[42,49,104,138,145,171,186,207,235,257,276,312],"cerebellar":[43,79,102,239],"D2":[44],"activity,":[45],"which":[46],"could":[47],"result":[48],"local":[50,297],"T3":[52],"deficiency.":[53],"also":[56,266],"begun":[57],"examine":[59,88],"TM":[60,84,259,275,287,303,311],"effect":[61],"gene":[63,80,131,213],"expression.":[64],"The":[65,174],"objective":[66],"this":[68],"study":[69],"was":[70,136,203],"expand":[72],"our":[74,294],"initial":[75],"observation":[76],"altered":[78,206,222],"expression":[81,126,170,175,223],"following":[82],"additional":[89],"genes":[90,99,233,282],"include":[92],"both":[93],"TH-dependent":[94,248],"as":[95,97],"well":[96],"other":[98],"critical":[100],"for":[101,121],"male":[105,261],"female":[107],"neonates":[108],"exposed":[109,260],"perinatally":[110],"(G10-G15":[111],"P5":[113],"P10)":[115],"TM.":[117],"report":[119],"here":[120],"first":[123],"time":[124],"suppressor-of-white-apricot-1":[128],"(SWAP-1),":[129],"negatively":[132,289],"T3,":[135],"increased":[137],"TM-exposed":[139,172,187],"males":[140,277],"(61.1%":[141],"increase),":[142],"but":[143],"not":[144,204],"females;":[146],"(p<0.05).":[147],"Positively":[148],"T3-target":[150],"genes,":[151],"Purkinje":[152],"cell":[153],"protein":[154,161],"2":[155,178],"(Pcp2;":[156],"p=0.07)":[157],"Forkhead":[159],"box":[160],"P4":[162],"(FoxP4;":[163],"p=0.08),":[164],"showed":[165,180],"trend":[167,182],"towards":[168,183],"decreased":[169],"males.":[173],"deiodinase":[177,190],"(DIO2)":[179],"an":[184],"increase":[185],"females,":[188],"while":[189],"3":[191],"(DIO3),":[192],"transthyretin":[193],"(TTR),":[194],"derived":[196],"neurotrophic":[197],"factor":[198],"(BDNF)":[199],"reelin":[201],"(RELN)":[202],"significantly":[205],"either":[208],"sex.":[209],"Since":[210],"regulation":[211,237],"splicing":[214],"vital":[216],"neuronal":[218],"proliferation":[219],"differentiation,":[221],"SWAP-1":[225],"may":[226],"exert":[227],"wide":[228],"ranging":[229],"multiple":[232],"involved":[234],"development.":[240],"identified":[244],"activation":[245],"another":[247],"gene,":[249],"outer":[250],"dense":[251],"fiber":[252],"sperm":[254],"tails":[255],"4,":[256],"pups.":[262],"Together,":[263],"these":[264],"results":[265],"show":[267],"sex-dependent":[268],"differences":[269],"between":[270],"toxic":[272],"impacts":[273],"females.":[279],"Interestingly,":[280],"were":[284],"activated":[285],"are":[288],"TH,":[292],"supporting":[293],"hypothesis":[295],"hypothyroidism":[299],"being":[300],"induced":[301],"suggesting":[305],"novel":[307],"mechanism":[308],"brain.":[315]},"counts_by_year":[{"year":2024,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":4},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}