{"id":"https://openalex.org/W2109078253","doi":"https://doi.org/10.1523/jneurosci.5619-08.2009","title":"Segregated Populations of Hippocampal Principal CA1 Neurons Mediating Conditioning and Extinction of Contextual Fear","display_name":"Segregated Populations of Hippocampal Principal CA1 Neurons Mediating Conditioning and Extinction of Contextual Fear","publication_year":2009,"publication_date":"2009-03-18","ids":{"openalex":"https://openalex.org/W2109078253","doi":"https://doi.org/10.1523/jneurosci.5619-08.2009","mag":"2109078253","pmid":"https://pubmed.ncbi.nlm.nih.gov/19295145","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2892108"},"language":"en","primary_location":{"id":"doi:10.1523/jneurosci.5619-08.2009","doi":"https://doi.org/10.1523/jneurosci.5619-08.2009","is_oa":true,"landing_page_url":"https://doi.org/10.1523/jneurosci.5619-08.2009","pdf_url":"https://www.jneurosci.org/content/jneuro/29/11/3387.full.pdf","source":{"id":"https://openalex.org/S5555990","display_name":"Journal of Neuroscience","issn_l":"0270-6474","issn":["0270-6474","1529-2401"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319739","host_organization_name":"Society for Neuroscience","host_organization_lineage":["https://openalex.org/P4310319739"],"host_organization_lineage_names":["Society for Neuroscience"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Neuroscience","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://www.jneurosci.org/content/jneuro/29/11/3387.full.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5075346690","display_name":"Natalie Celia Tronson","orcid":"https://orcid.org/0000-0001-5676-1579","observed_orcids":["https://orcid.org/0000-0001-5676-1579"]},"institutions":[{"id":"https://openalex.org/I111979921","display_name":"Northwestern University","ror":"https://ror.org/000e0be47","country_code":"US","type":"education","lineage":["https://openalex.org/I111979921"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Natalie C. Tronson","raw_affiliation_strings":["Department of Psychiatry and Behavioral Sciences, The Asher Center for the Study, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry and Behavioral Sciences, The Asher Center for the Study, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA","institution_ids":["https://openalex.org/I111979921"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080438170","display_name":"Christina Schrick","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I111979921","display_name":"Northwestern University","ror":"https://ror.org/000e0be47","country_code":"US","type":"education","lineage":["https://openalex.org/I111979921"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Christina Schrick","raw_affiliation_strings":["Department of Psychiatry and Behavioral Sciences , The Asher Center for the Study and Treatment of Depressive Disorders , and","Northwestern University****"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry and Behavioral Sciences , The Asher Center for the Study and Treatment of Depressive Disorders , and","institution_ids":[]},{"raw_affiliation_string":"Northwestern University****","institution_ids":["https://openalex.org/I111979921"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060638295","display_name":"Yomayra F. Guzm\u00e1n","orcid":"https://orcid.org/0000-0003-4802-8304","observed_orcids":["https://orcid.org/0000-0003-4802-8304"]},"institutions":[{"id":"https://openalex.org/I111979921","display_name":"Northwestern University","ror":"https://ror.org/000e0be47","country_code":"US","type":"education","lineage":["https://openalex.org/I111979921"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yomayra F. Guzman","raw_affiliation_strings":["Department of Psychiatry and Behavioral Sciences , The Asher Center for the Study and Treatment of Depressive Disorders , and","Northwestern University****"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry and Behavioral Sciences , The Asher Center for the Study and Treatment of Depressive Disorders , and","institution_ids":[]},{"raw_affiliation_string":"Northwestern University****","institution_ids":["https://openalex.org/I111979921"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002970061","display_name":"Kyu Hwan Huh","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I111979921","display_name":"Northwestern University","ror":"https://ror.org/000e0be47","country_code":"US","type":"education","lineage":["https://openalex.org/I111979921"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kyu Hwan Huh","raw_affiliation_strings":["Department of Psychiatry and Behavioral Sciences , The Asher Center for the Study and Treatment of Depressive Disorders , and","Northwestern University****"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry and Behavioral Sciences , The Asher Center for the Study and Treatment of Depressive Disorders , and","institution_ids":[]},{"raw_affiliation_string":"Northwestern University****","institution_ids":["https://openalex.org/I111979921"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061410044","display_name":"Deepak P. Srivastava","orcid":"https://orcid.org/0000-0001-6512-9065","observed_orcids":["https://orcid.org/0000-0001-6512-9065"]},"institutions":[{"id":"https://openalex.org/I111979921","display_name":"Northwestern University","ror":"https://ror.org/000e0be47","country_code":"US","type":"education","lineage":["https://openalex.org/I111979921"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Deepak P. Srivastava","raw_affiliation_strings":["Department of Physiology , Feinberg School of Medicine , Northwestern University , Chicago , Illinois 60611","Northwestern University****"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology , Feinberg School of Medicine , Northwestern University , Chicago , Illinois 60611","institution_ids":["https://openalex.org/I111979921"]},{"raw_affiliation_string":"Northwestern University****","institution_ids":["https://openalex.org/I111979921"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071692996","display_name":"Peter Penzes","orcid":"https://orcid.org/0000-0001-5449-1640","observed_orcids":["https://orcid.org/0000-0001-5449-1640"]},"institutions":[{"id":"https://openalex.org/I111979921","display_name":"Northwestern University","ror":"https://ror.org/000e0be47","country_code":"US","type":"education","lineage":["https://openalex.org/I111979921"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Peter Penzes","raw_affiliation_strings":["Department of Physiology , Feinberg School of Medicine , Northwestern University , Chicago , Illinois 60611","Northwestern University****"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology , Feinberg School of Medicine , Northwestern University , Chicago , Illinois 60611","institution_ids":["https://openalex.org/I111979921"]},{"raw_affiliation_string":"Northwestern University****","institution_ids":["https://openalex.org/I111979921"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055102546","display_name":"Anita L. Guedea","orcid":"https://orcid.org/0000-0002-9446-3668","observed_orcids":["https://orcid.org/0000-0002-9446-3668"]},"institutions":[{"id":"https://openalex.org/I111979921","display_name":"Northwestern University","ror":"https://ror.org/000e0be47","country_code":"US","type":"education","lineage":["https://openalex.org/I111979921"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Anita L. Guedea","raw_affiliation_strings":["Department of Psychiatry and Behavioral Sciences , The Asher Center for the Study and Treatment of Depressive Disorders , and","Northwestern University****"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry and Behavioral Sciences , The Asher Center for the Study and Treatment of Depressive Disorders , and","institution_ids":[]},{"raw_affiliation_string":"Northwestern University****","institution_ids":["https://openalex.org/I111979921"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071014600","display_name":"Can Gao","orcid":"https://orcid.org/0000-0001-5552-9639","observed_orcids":["https://orcid.org/0000-0001-5552-9639"]},"institutions":[{"id":"https://openalex.org/I111979921","display_name":"Northwestern University","ror":"https://ror.org/000e0be47","country_code":"US","type":"education","lineage":["https://openalex.org/I111979921"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Can Gao","raw_affiliation_strings":["Department of Psychiatry and Behavioral Sciences , The Asher Center , Feinberg School of Medicine , Northwestern University , 303 East Chicago Avenue , Ward 9-221 , Chicago , IL 60611-3008","Department of Psychiatry and Behavioral Sciences , The Asher Center for the Study and Treatment of Depressive Disorders , and","Northwestern University****"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry and Behavioral Sciences , The Asher Center , Feinberg School of Medicine , Northwestern University , 303 East Chicago Avenue , Ward 9-221 , Chicago , IL 60611-3008","institution_ids":["https://openalex.org/I111979921"]},{"raw_affiliation_string":"Department of Psychiatry and Behavioral Sciences , The Asher Center for the Study and Treatment of Depressive Disorders , and","institution_ids":[]},{"raw_affiliation_string":"Northwestern University****","institution_ids":["https://openalex.org/I111979921"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5029897160","display_name":"Jelena Radulovi\u0107","orcid":"https://orcid.org/0000-0002-0268-2426","observed_orcids":["https://orcid.org/0000-0002-0268-2426"]},"institutions":[{"id":"https://openalex.org/I111979921","display_name":"Northwestern University","ror":"https://ror.org/000e0be47","country_code":"US","type":"education","lineage":["https://openalex.org/I111979921"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jelena Radulovic","raw_affiliation_strings":["Department of Psychiatry and Behavioral Sciences , The Asher Center for the Study and Treatment of Depressive Disorders , and","Northwestern University****"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry and Behavioral Sciences , The Asher Center for the Study and Treatment of Depressive Disorders , and","institution_ids":[]},{"raw_affiliation_string":"Northwestern University****","institution_ids":["https://openalex.org/I111979921"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I111979921"],"apc_list":null,"apc_paid":null,"fwci":4.0715,"has_fulltext":true,"cited_by_count":143,"citation_normalized_percentile":{"value":0.9410217,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":93,"max":99},"biblio":{"volume":"29","issue":"11","first_page":"3387","last_page":"3394"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10448","display_name":"Memory and Neural Mechanisms","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10448","display_name":"Memory and Neural Mechanisms","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10608","display_name":"Neurogenesis and neuroplasticity mechanisms","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2806","display_name":"Developmental Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/contextual-fear","display_name":"contextual fear","score":0.8539999723434448},{"id":"https://openalex.org/keywords/fear-extinction","display_name":"fear extinction","score":0.8849999904632568},{"id":"https://openalex.org/keywords/fear-conditioning","display_name":"fear conditioning","score":0.9860000014305115},{"id":"https://openalex.org/keywords/ca1-pyramidal-neurons","display_name":"CA1 pyramidal neurons","score":0.9340000152587891},{"id":"https://openalex.org/keywords/c-fos","display_name":"c-fos","score":0.8429999947547913},{"id":"https://openalex.org/keywords/extracellular-signal-regulated-kinase","display_name":"extracellular signal-regulated kinase","score":0.9459999799728394},{"id":"https://openalex.org/keywords/erk-signaling","display_name":"ERK signaling","score":0.8050000071525574},{"id":"https://openalex.org/keywords/medial-septum","display_name":"medial septum","score":0.7639999985694885},{"id":"https://openalex.org/keywords/cholinergic-input","display_name":"cholinergic input","score":0.9440000057220459},{"id":"https://openalex.org/keywords/fear-memory-consolidation","display_name":"fear memory consolidation","score":0.7689999938011169}],"concepts":[{"id":"https://openalex.org/C16837860","wikidata":"https://www.wikidata.org/wiki/Q2079841","display_name":"Fear conditioning","level":3,"score":0.7804020643234253},{"id":"https://openalex.org/C101991246","wikidata":"https://www.wikidata.org/wiki/Q5422078","display_name":"Extinction (optical mineralogy)","level":2,"score":0.747189998626709},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.7271324992179871},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.6800879836082458},{"id":"https://openalex.org/C148762608","wikidata":"https://www.wikidata.org/wiki/Q3748185","display_name":"Hippocampal formation","level":2,"score":0.6318913698196411},{"id":"https://openalex.org/C45262634","wikidata":"https://www.wikidata.org/wiki/Q5159291","display_name":"Conditioning","level":2,"score":0.5490673780441284},{"id":"https://openalex.org/C100798922","wikidata":"https://www.wikidata.org/wiki/Q5439409","display_name":"Fear processing in the brain","level":4,"score":0.5336447954177856},{"id":"https://openalex.org/C180747234","wikidata":"https://www.wikidata.org/wiki/Q23373","display_name":"Cognitive psychology","level":1,"score":0.4486534297466278},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2792494297027588},{"id":"https://openalex.org/C2779144063","wikidata":"https://www.wikidata.org/wiki/Q338924","display_name":"Amygdala","level":2,"score":0.18350285291671753},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.0},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003213","descriptor_name":"Conditioning, Psychological","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D005108","descriptor_name":"Extinction, Psychological","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D005239","descriptor_name":"Fear","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D005239","descriptor_name":"Fear","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":false},{"descriptor_ui":"D006624","descriptor_name":"Hippocampus","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D006624","descriptor_name":"Hippocampus","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D008810","descriptor_name":"Mice, Inbred C57BL","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008822","descriptor_name":"Mice, Transgenic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1523/jneurosci.5619-08.2009","doi":"https://doi.org/10.1523/jneurosci.5619-08.2009","is_oa":true,"landing_page_url":"https://doi.org/10.1523/jneurosci.5619-08.2009","pdf_url":"https://www.jneurosci.org/content/jneuro/29/11/3387.full.pdf","source":{"id":"https://openalex.org/S5555990","display_name":"Journal of Neuroscience","issn_l":"0270-6474","issn":["0270-6474","1529-2401"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319739","host_organization_name":"Society for Neuroscience","host_organization_lineage":["https://openalex.org/P4310319739"],"host_organization_lineage_names":["Society for Neuroscience"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Neuroscience","raw_type":"journal-article"},{"id":"pmid:19295145","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19295145","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of neuroscience : the official journal of the Society for Neuroscience","raw_type":"Comparative Study"},{"id":"pmh:oai:pubmedcentral.nih.gov:2892108","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC2892108/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"J Neurosci","raw_type":"Text"},{"id":"mag:2740256978","doi":null,"is_oa":false,"landing_page_url":"https://www.jneurosci.org/content/29/11/3387.full.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"doi:10.1523/jneurosci.5619-08.2009","doi":"https://doi.org/10.1523/jneurosci.5619-08.2009","is_oa":true,"landing_page_url":"https://doi.org/10.1523/jneurosci.5619-08.2009","pdf_url":"https://www.jneurosci.org/content/jneuro/29/11/3387.full.pdf","source":{"id":"https://openalex.org/S5555990","display_name":"Journal of Neuroscience","issn_l":"0270-6474","issn":["0270-6474","1529-2401"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319739","host_organization_name":"Society for Neuroscience","host_organization_lineage":["https://openalex.org/P4310319739"],"host_organization_lineage_names":["Society for Neuroscience"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Neuroscience","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.504800021648407}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1544869584","display_name":"Hippocampal Mechanisms of Fear Extinction","funder_award_id":"R01MH073669","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"}],"funders":[{"id":"https://openalex.org/F4320309475","display_name":"Northwestern University","ror":"https://ror.org/000e0be47"},{"id":"https://openalex.org/F4320337346","display_name":"National Institute of Mental Health","ror":"https://ror.org/04xeg9z08"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2109078253.pdf","grobid_xml":"https://content.openalex.org/works/W2109078253.grobid-xml"},"referenced_works_count":47,"referenced_works":["https://openalex.org/W1527550792","https://openalex.org/W1545836459","https://openalex.org/W1562926869","https://openalex.org/W1633118497","https://openalex.org/W1670447597","https://openalex.org/W1675950512","https://openalex.org/W1801803313","https://openalex.org/W1967887989","https://openalex.org/W1967888214","https://openalex.org/W1970316545","https://openalex.org/W1972528511","https://openalex.org/W1981675681","https://openalex.org/W1989045560","https://openalex.org/W1989085266","https://openalex.org/W1992811119","https://openalex.org/W2005833530","https://openalex.org/W2009000833","https://openalex.org/W2011291368","https://openalex.org/W2019438547","https://openalex.org/W2021243967","https://openalex.org/W2026609418","https://openalex.org/W2026663553","https://openalex.org/W2036855091","https://openalex.org/W2039891360","https://openalex.org/W2042295311","https://openalex.org/W2042479971","https://openalex.org/W2046861885","https://openalex.org/W2062948660","https://openalex.org/W2065847146","https://openalex.org/W2067779334","https://openalex.org/W2071456539","https://openalex.org/W2077452637","https://openalex.org/W2082235945","https://openalex.org/W2086544038","https://openalex.org/W2092433366","https://openalex.org/W2093068062","https://openalex.org/W2101626807","https://openalex.org/W2124284324","https://openalex.org/W2145117124","https://openalex.org/W2145465887","https://openalex.org/W2154879280","https://openalex.org/W2162949605","https://openalex.org/W2162958801","https://openalex.org/W2166888266","https://openalex.org/W2169294911","https://openalex.org/W3021286032","https://openalex.org/W7096203747"],"related_works":["https://openalex.org/W1989085266","https://openalex.org/W2602469503","https://openalex.org/W2804732778","https://openalex.org/W2141638608","https://openalex.org/W2179194282","https://openalex.org/W2083759500","https://openalex.org/W4387007798","https://openalex.org/W1992811119","https://openalex.org/W2077043733","https://openalex.org/W1984029166"],"abstract_inverted_index":{"Learning":[0],"processes":[1],"mediating":[2],"conditioning":[3,26,87,134,154],"and":[4,35,44,88,102,108,121,135,194,202],"extinction":[5,89,136,195,208],"of":[6,11,31,47,62,86,90,100,119,130,137,173,180,196,218],"contextual":[7,48],"fear":[8,25,49,63,197],"require":[9],"activation":[10,30,129,193],"several":[12],"key":[13],"signaling":[14,166,213],"pathways":[15],"in":[16,76,148,170],"the":[17,97,115,188,229],"hippocampus.":[18],"Principal":[19],"hippocampal":[20,151,174],"CA1":[21,219],"neurons":[22,221],"respond":[23],"to":[24,95,146],"by":[27,110,124,156,224],"a":[28,59,215],"coordinated":[29],"multiple":[32],"protein":[33,132],"kinases":[34],"immediate":[36],"early":[37],"genes,":[38],"such":[39],"as":[40,58],"cFos,":[41],"enabling":[42],"rapid":[43],"lasting":[45],"consolidation":[46],"memory.":[50],"The":[51,161],"extracellular":[52],"signal-regulated":[53],"kinase":[54],"(Erk)":[55],"additionally":[56],"acts":[57],"central":[60],"mediator":[61],"extinction.":[64,160],"It":[65],"is":[66],"not":[67],"known":[68],"however,":[69],"whether":[70],"these":[71,165],"molecular":[72],"events":[73],"take":[74],"place":[75],"overlapping":[77],"or":[78],"nonoverlapping":[79],"neuronal":[80],"populations.":[81],"By":[82],"using":[83],"mouse":[84],"models":[85],"fear,":[91,138],"we":[92],"set":[93],"out":[94],"determine":[96],"time":[98],"course":[99],"cFos":[101,200],"Erk":[103,192,212],"activity,":[104],"their":[105],"cellular":[106],"overlap,":[107],"regulation":[109],"afferent":[111,225],"cholinergic":[112,185,226],"input":[113,186,227],"from":[114,228],"medial":[116,181,230],"septum.":[117,231],"Analyses":[118],"cFos(+)":[120],"pErk(+)":[122],"cells":[123,152],"immunofluorescence":[125],"revealed":[126],"predominant":[127],"nuclear":[128],"either":[131],"during":[133,153],"respectively.":[139],"Transgenic":[140],"cFos-LacZ":[141],"mice":[142],"were":[143,168],"further":[144],"used":[145],"label":[147],"vivo":[149],"Fos(+)":[150],"followed":[155],"pErk":[157],"immunostaining":[158],"after":[159],"results":[162,205],"showed":[163],"that":[164,207],"molecules":[167],"activated":[169],"segregated":[171],"populations":[172],"principal":[175,220],"neurons.":[176],"Furthermore,":[177],"immunotoxin-induced":[178],"lesions":[179],"septal":[182],"neurons,":[183],"providing":[184],"into":[187],"hippocampus,":[189],"selectively":[190],"abolished":[191],"without":[198],"affecting":[199],"responses":[201],"conditioning.":[203],"These":[204],"demonstrate":[206],"mechanisms":[209],"based":[210],"on":[211],"involve":[214],"specific":[216],"population":[217],"distinctively":[222],"regulated":[223]},"counts_by_year":[{"year":2026,"cited_by_count":5},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":8},{"year":2023,"cited_by_count":7},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":13},{"year":2020,"cited_by_count":11},{"year":2019,"cited_by_count":10},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":9},{"year":2016,"cited_by_count":8},{"year":2015,"cited_by_count":11},{"year":2014,"cited_by_count":8},{"year":2013,"cited_by_count":13},{"year":2012,"cited_by_count":8}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}