{"id":"https://openalex.org/W2109045926","doi":"https://doi.org/10.1016/j.jmb.2010.04.056","title":"Calcium-Induced Folding of a Beta Roll Motif Requires C-Terminal Entropic Stabilization","display_name":"Calcium-Induced Folding of a Beta Roll Motif Requires C-Terminal Entropic Stabilization","publication_year":2010,"publication_date":"2010-05-03","ids":{"openalex":"https://openalex.org/W2109045926","doi":"https://doi.org/10.1016/j.jmb.2010.04.056","mag":"2109045926","pmid":"https://pubmed.ncbi.nlm.nih.gov/20438736"},"language":"en","primary_location":{"id":"doi:10.1016/j.jmb.2010.04.056","doi":"https://doi.org/10.1016/j.jmb.2010.04.056","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jmb.2010.04.056","pdf_url":null,"source":{"id":"https://openalex.org/S46058472","display_name":"Journal of Molecular Biology","issn_l":"0022-2836","issn":["0022-2836","1089-8638"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Molecular Biology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5006285317","display_name":"Mark Blenner","orcid":"https://orcid.org/0000-0001-9274-3749","observed_orcids":["https://orcid.org/0000-0001-9274-3749"]},"institutions":[{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mark A. Blenner","raw_affiliation_strings":["Department of Chemical Engineering, Columbia University, 500 W 120th Street, New York, NY 10027, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical Engineering, Columbia University, 500 W 120th Street, New York, NY 10027, USA","institution_ids":["https://openalex.org/I78577930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034442265","display_name":"Oren Shur","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Oren Shur","raw_affiliation_strings":["Department of Chemical Engineering, Columbia University, 500 W 120th Street, New York, NY 10027, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical Engineering, Columbia University, 500 W 120th Street, New York, NY 10027, USA","institution_ids":["https://openalex.org/I78577930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088269067","display_name":"G\u00e9za R. Szilvay","orcid":"https://orcid.org/0000-0002-2718-751X","observed_orcids":["https://orcid.org/0000-0002-2718-751X"]},"institutions":[{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"G\u00e9za R. Szilvay","raw_affiliation_strings":["Department of Chemical Engineering, Columbia University, 500 W 120th Street, New York, NY 10027, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical Engineering, Columbia University, 500 W 120th Street, New York, NY 10027, USA","institution_ids":["https://openalex.org/I78577930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056535522","display_name":"Donald M. Cropek","orcid":"https://orcid.org/0000-0002-6312-5578","observed_orcids":["https://orcid.org/0000-0002-6312-5578"]},"institutions":[{"id":"https://openalex.org/I4210088792","display_name":"United States Army","ror":"https://ror.org/00afsp483","country_code":"US","type":"government","lineage":["https://openalex.org/I1304082316","https://openalex.org/I1330347796","https://openalex.org/I4210088792"]},{"id":"https://openalex.org/I4400009010","display_name":"Construction Engineering Research Laboratory","ror":"https://ror.org/003mzyg61","country_code":"US","type":"facility","lineage":["https://openalex.org/I1304082316","https://openalex.org/I1306490931","https://openalex.org/I1330347796","https://openalex.org/I4400009010","https://openalex.org/I87303767"]},{"id":"https://openalex.org/I87303767","display_name":"U.S. Army Engineer Research and Development Center","ror":"https://ror.org/027mhn368","country_code":"US","type":"facility","lineage":["https://openalex.org/I1304082316","https://openalex.org/I1306490931","https://openalex.org/I1330347796","https://openalex.org/I87303767"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Donald M. Cropek","raw_affiliation_strings":["U.S. Army Engineer Research and Development Center, Construction Engineering Research Laboratory (CERL), Champaign, IL 61822, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"U.S. Army Engineer Research and Development Center, Construction Engineering Research Laboratory (CERL), Champaign, IL 61822, USA","institution_ids":["https://openalex.org/I4210088792","https://openalex.org/I4400009010","https://openalex.org/I87303767"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5063109716","display_name":"Scott A. Banta","orcid":"https://orcid.org/0000-0001-7885-0150","observed_orcids":["https://orcid.org/0000-0001-7885-0150"]},"institutions":[{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Scott Banta","raw_affiliation_strings":["Department of Chemical Engineering, Columbia University, 500 W 120th Street, New York, NY 10027, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical Engineering, Columbia University, 500 W 120th Street, New York, NY 10027, USA","institution_ids":["https://openalex.org/I78577930"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5063109716"],"corresponding_institution_ids":["https://openalex.org/I78577930"],"apc_list":{"value":4730,"currency":"USD","value_usd":4730},"apc_paid":null,"fwci":2.0828,"has_fulltext":false,"cited_by_count":60,"citation_normalized_percentile":{"value":0.86741214,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":99},"biblio":{"volume":"400","issue":"2","first_page":"244","last_page":"256"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.98580002784729,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.98580002784729,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13326","display_name":"Biochemical and Structural Characterization","score":0.00430000014603138,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11124","display_name":"Protein purification and stability","score":0.0010999999940395355,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/type-1-secretion-system","display_name":"type 1 secretion system","score":0.8830000162124634},{"id":"https://openalex.org/keywords/protein-folding","display_name":"protein folding","score":0.3409999907016754},{"id":"https://openalex.org/keywords/calcium-binding-affinity","display_name":"calcium affinity","score":0.5619999766349792}],"concepts":[{"id":"https://openalex.org/C519063684","wikidata":"https://www.wikidata.org/wiki/Q706","display_name":"Calcium","level":2,"score":0.6472823619842529},{"id":"https://openalex.org/C49039625","wikidata":"https://www.wikidata.org/wiki/Q84230","display_name":"Secretion","level":2,"score":0.543363094329834},{"id":"https://openalex.org/C57711820","wikidata":"https://www.wikidata.org/wiki/Q310425","display_name":"C-terminus","level":3,"score":0.5386267900466919},{"id":"https://openalex.org/C204328495","wikidata":"https://www.wikidata.org/wiki/Q847556","display_name":"Protein folding","level":2,"score":0.4810962378978729},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.46771329641342163},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.4651886522769928},{"id":"https://openalex.org/C14053116","wikidata":"https://www.wikidata.org/wiki/Q284398","display_name":"N-terminus","level":4,"score":0.4338718354701996},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.4269304871559143},{"id":"https://openalex.org/C117745874","wikidata":"https://www.wikidata.org/wiki/Q901612","display_name":"Sequence motif","level":3,"score":0.41700229048728943},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.34347206354141235},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.32682740688323975},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.3218362331390381},{"id":"https://openalex.org/C167625842","wikidata":"https://www.wikidata.org/wiki/Q899763","display_name":"Peptide sequence","level":3,"score":0.310130774974823},{"id":"https://openalex.org/C515207424","wikidata":"https://www.wikidata.org/wiki/Q8066","display_name":"Amino acid","level":2,"score":0.23628643155097961},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.12246403098106384},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D002118","descriptor_name":"Calcium","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D002942","descriptor_name":"Circular Dichroism","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011092","descriptor_name":"Polyethylene Glycols","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D011993","descriptor_name":"Recombinant Fusion Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D011993","descriptor_name":"Recombinant Fusion Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011993","descriptor_name":"Recombinant Fusion Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D013057","descriptor_name":"Spectrum Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D017386","descriptor_name":"Sequence Homology, Amino Acid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017433","descriptor_name":"Protein Structure, Secondary","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017510","descriptor_name":"Protein Folding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020816","descriptor_name":"Amino Acid Motifs","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D037361","descriptor_name":"Adenylate Cyclase Toxin","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D037361","descriptor_name":"Adenylate Cyclase Toxin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D037361","descriptor_name":"Adenylate Cyclase Toxin","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.jmb.2010.04.056","doi":"https://doi.org/10.1016/j.jmb.2010.04.056","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jmb.2010.04.056","pdf_url":null,"source":{"id":"https://openalex.org/S46058472","display_name":"Journal of Molecular Biology","issn_l":"0022-2836","issn":["0022-2836","1089-8638"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Molecular Biology","raw_type":"journal-article"},{"id":"pmid:20438736","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20438736","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of molecular biology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320332186","display_name":"Defense Threat Reduction Agency","ror":"https://ror.org/04tz64554"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":51,"referenced_works":["https://openalex.org/W43726920","https://openalex.org/W1487053853","https://openalex.org/W1493603787","https://openalex.org/W1678098555","https://openalex.org/W1892148740","https://openalex.org/W1964794469","https://openalex.org/W1970505356","https://openalex.org/W1980685592","https://openalex.org/W1981045929","https://openalex.org/W1988456728","https://openalex.org/W1989270637","https://openalex.org/W1990388735","https://openalex.org/W1990659194","https://openalex.org/W1995036584","https://openalex.org/W1995838356","https://openalex.org/W1997052610","https://openalex.org/W2022959668","https://openalex.org/W2024056647","https://openalex.org/W2025551193","https://openalex.org/W2028129929","https://openalex.org/W2028320405","https://openalex.org/W2035428213","https://openalex.org/W2036846779","https://openalex.org/W2038591054","https://openalex.org/W2041918990","https://openalex.org/W2047713394","https://openalex.org/W2049291900","https://openalex.org/W2049477140","https://openalex.org/W2049994974","https://openalex.org/W2052639284","https://openalex.org/W2056399792","https://openalex.org/W2062166748","https://openalex.org/W2081843165","https://openalex.org/W2084938664","https://openalex.org/W2092390193","https://openalex.org/W2092803887","https://openalex.org/W2111433307","https://openalex.org/W2115746274","https://openalex.org/W2119827607","https://openalex.org/W2121635781","https://openalex.org/W2125022522","https://openalex.org/W2127068865","https://openalex.org/W2128055699","https://openalex.org/W2133691154","https://openalex.org/W2136617021","https://openalex.org/W2149936753","https://openalex.org/W2163268846","https://openalex.org/W2164148522","https://openalex.org/W2171810874","https://openalex.org/W2911775888","https://openalex.org/W4210968583"],"related_works":["https://openalex.org/W2145383898","https://openalex.org/W2044636054","https://openalex.org/W2040252169","https://openalex.org/W2022959668","https://openalex.org/W2784054231","https://openalex.org/W1997052610","https://openalex.org/W7008232117","https://openalex.org/W3004550763","https://openalex.org/W4385691701","https://openalex.org/W4396957106"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":5},{"year":2016,"cited_by_count":4},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":7},{"year":2013,"cited_by_count":6},{"year":2012,"cited_by_count":5}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}