{"id":"https://openalex.org/W2108907694","doi":"https://doi.org/10.5897/jmpr10.349","title":"Protective effect of Murraya koenigii (L) leaves extract in streptozotocin induced diabetics rats involving possible antioxidant mechanism","display_name":"Protective effect of Murraya koenigii (L) leaves extract in streptozotocin induced diabetics rats involving possible antioxidant mechanism","publication_year":2010,"publication_date":"2010-11-18","ids":{"openalex":"https://openalex.org/W2108907694","doi":"https://doi.org/10.5897/jmpr10.349","mag":"2108907694"},"language":"en","primary_location":{"id":"mag:2108907694","doi":"https://doi.org/10.5897/jmpr10.349","is_oa":true,"landing_page_url":"https://academicjournals.org/journal/JMPR/article-abstract/8CD692C21084","pdf_url":null,"source":{"id":"https://openalex.org/S157481311","display_name":"Journal of Medicinal Plants Research","issn_l":"1996-0875","issn":["1996-0875"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310321074","host_organization_name":"Academic Journals","host_organization_lineage":["https://openalex.org/P4310321074"],"host_organization_lineage_names":["Academic Journals"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Journal of Medicinal Plants Research","raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://academicjournals.org/journal/JMPR/article-abstract/8CD692C21084","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111661945","display_name":"S. V. Tembhurne","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"S. V. Tembhurne","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5112100755","display_name":"D. M. Sakarkar","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"D. M. Sakarkar","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.5526,"has_fulltext":false,"cited_by_count":31,"citation_normalized_percentile":{"value":0.82130794,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"4","issue":"22","first_page":"2418","last_page":"2423"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11140","display_name":"Natural Antidiabetic Agents Studies","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11140","display_name":"Natural Antidiabetic Agents Studies","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T14521","display_name":"Medicinal Plant Research","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12298","display_name":"Phytochemicals and Medicinal Plants","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/murraya-koenigii","display_name":"Murraya koenigii","score":1.0},{"id":"https://openalex.org/keywords/streptozotocin-induced-diabetes","display_name":"streptozotocin-induced diabetes","score":0.9110000133514404},{"id":"https://openalex.org/keywords/antidiabetic-activity","display_name":"antidiabetic activity","score":0.8759999871253967},{"id":"https://openalex.org/keywords/antioxidant-activity","display_name":"antioxidant activity","score":0.9160000085830688},{"id":"https://openalex.org/keywords/oxidative-stress","display_name":"oxidative stress","score":0.9129999876022339},{"id":"https://openalex.org/keywords/lipid-peroxidation","display_name":"lipid peroxidation","score":0.9810000061988831},{"id":"https://openalex.org/keywords/thiobarbituric-acid-reactive-substances","display_name":"TBARS","score":0.8870000243186951},{"id":"https://openalex.org/keywords/glycemic-control","display_name":"glycemic control","score":0.902999997138977},{"id":"https://openalex.org/keywords/glycosylated-haemoglobin","display_name":"glycosylated haemoglobin","score":0.8930000066757202},{"id":"https://openalex.org/keywords/blood-glucose","display_name":"blood glucose","score":0.7440000176429749},{"id":"https://openalex.org/keywords/glycogen","display_name":"glycogen","score":0.8809999823570251},{"id":"https://openalex.org/keywords/glibenclamide","display_name":"glibenclamide","score":0.8169999718666077},{"id":"https://openalex.org/keywords/carbazole-alkaloids","display_name":"carbazole alkaloids","score":0.8379999995231628},{"id":"https://openalex.org/keywords/phenolic-compounds","display_name":"phenolic compounds","score":0.7319999933242798},{"id":"https://openalex.org/keywords/triterpenoids","display_name":"triterpenoids","score":0.7910000085830688}],"concepts":[{"id":"https://openalex.org/C2778539424","wikidata":"https://www.wikidata.org/wiki/Q1641850","display_name":"Murraya","level":2,"score":0.9884604215621948},{"id":"https://openalex.org/C2777352226","wikidata":"https://www.wikidata.org/wiki/Q7669516","display_name":"TBARS","level":4,"score":0.9660058617591858},{"id":"https://openalex.org/C2778004101","wikidata":"https://www.wikidata.org/wiki/Q133948","display_name":"Antioxidant","level":2,"score":0.7972503900527954},{"id":"https://openalex.org/C2779280383","wikidata":"https://www.wikidata.org/wiki/Q257331","display_name":"Streptozotocin","level":3,"score":0.7441344857215881},{"id":"https://openalex.org/C2780829032","wikidata":"https://www.wikidata.org/wiki/Q898539","display_name":"Lipid peroxidation","level":3,"score":0.6542432904243469},{"id":"https://openalex.org/C2777504301","wikidata":"https://www.wikidata.org/wiki/Q418230","display_name":"Thiobarbituric acid","level":4,"score":0.6323021054267883},{"id":"https://openalex.org/C2776151105","wikidata":"https://www.wikidata.org/wiki/Q898814","display_name":"Oxidative stress","level":2,"score":0.5869152545928955},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.5792683959007263},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5602014064788818},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.5561658143997192},{"id":"https://openalex.org/C2779768347","wikidata":"https://www.wikidata.org/wiki/Q420626","display_name":"Glibenclamide","level":3,"score":0.5446712970733643},{"id":"https://openalex.org/C556039675","wikidata":"https://www.wikidata.org/wiki/Q771035","display_name":"Traditional medicine","level":1,"score":0.41558152437210083},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.33483195304870605},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.26992282271385193},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.1611185371875763}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2108907694","doi":"https://doi.org/10.5897/jmpr10.349","is_oa":true,"landing_page_url":"https://academicjournals.org/journal/JMPR/article-abstract/8CD692C21084","pdf_url":null,"source":{"id":"https://openalex.org/S157481311","display_name":"Journal of Medicinal Plants Research","issn_l":"1996-0875","issn":["1996-0875"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310321074","host_organization_name":"Academic Journals","host_organization_lineage":["https://openalex.org/P4310321074"],"host_organization_lineage_names":["Academic Journals"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Journal of Medicinal Plants Research","raw_type":null}],"best_oa_location":{"id":"mag:2108907694","doi":"https://doi.org/10.5897/jmpr10.349","is_oa":true,"landing_page_url":"https://academicjournals.org/journal/JMPR/article-abstract/8CD692C21084","pdf_url":null,"source":{"id":"https://openalex.org/S157481311","display_name":"Journal of Medicinal Plants Research","issn_l":"1996-0875","issn":["1996-0875"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310321074","host_organization_name":"Academic Journals","host_organization_lineage":["https://openalex.org/P4310321074"],"host_organization_lineage_names":["Academic Journals"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Journal of Medicinal Plants Research","raw_type":null},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9391000270843506,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":35,"referenced_works":["https://openalex.org/W259831642","https://openalex.org/W569326643","https://openalex.org/W573972951","https://openalex.org/W1505111440","https://openalex.org/W1966340295","https://openalex.org/W1971876264","https://openalex.org/W1983310681","https://openalex.org/W2000611258","https://openalex.org/W2001444091","https://openalex.org/W2007972080","https://openalex.org/W2013830975","https://openalex.org/W2018356077","https://openalex.org/W2020265334","https://openalex.org/W2020777107","https://openalex.org/W2024300266","https://openalex.org/W2036939737","https://openalex.org/W2038087749","https://openalex.org/W2051916308","https://openalex.org/W2072903912","https://openalex.org/W2073620575","https://openalex.org/W2076783987","https://openalex.org/W2086149935","https://openalex.org/W2108688009","https://openalex.org/W2111653865","https://openalex.org/W2115337518","https://openalex.org/W2124098523","https://openalex.org/W2139169583","https://openalex.org/W2156902158","https://openalex.org/W2161849974","https://openalex.org/W2184255809","https://openalex.org/W2280495395","https://openalex.org/W2330960323","https://openalex.org/W2340609789","https://openalex.org/W2401495726","https://openalex.org/W2417574190"],"related_works":["https://openalex.org/W7218228259","https://openalex.org/W2803941569","https://openalex.org/W2900513976","https://openalex.org/W2007349600","https://openalex.org/W2955419888","https://openalex.org/W3170460208","https://openalex.org/W2274773529","https://openalex.org/W3083328526","https://openalex.org/W2749468982","https://openalex.org/W2963348243"],"abstract_inverted_index":{"Diabetes":[0],"causes":[1],"increased":[2],"oxidative":[3],"stress,":[4],"which":[5,159],"is":[6],"thought":[7],"to":[8,25,41,126,132,163,188],"play":[9],"an":[10],"important":[11],"role":[12],"in":[13,67,97,119,142],"the":[14,34,37,43,64,83,146,151,164,180,189],"pathogenesis":[15],"of":[16,36,46,59,73,76,85,112,166,191],"various":[17],"diabetic":[18,70,100,120,143],"complications.":[19,32],"The":[20,109],"antioxidant":[21,44,157,193],"actions":[22],"are":[23],"keys":[24],"preventing":[26],"or":[27],"reversing":[28],"diabetes":[29],"and":[30,62,79,92,176],"its":[31,192],"Thus":[33,179],"aim":[35],"present":[38],"study":[39],"was":[40,103,185],"evaluate":[42],"potential":[45],"ethanolic\u00a0Murraya":[47],"koenigii\u00a0leaves":[48,184],"(MKL)":[49],"extract":[50,153],"on":[51,63,82,90],"Thiobarbituric":[52],"Acid":[53],"Reactive":[54],"Substances":[55],"(TBARS)":[56],"as":[57,105,171],"index":[58],"lipid":[60],"peroxidation":[61],"glycemic":[65],"control":[66,127],"streptozotocin":[68,98],"induced":[69,99],"rats.":[71,101,144],"Effect":[72],"oral":[74],"administration":[75],"MKL":[77,138],"(300":[78],"500":[80],"mg/kg)":[81],"level":[84,111,134],"blood":[86,113],"glucose,":[87,114],"glycosylated":[88,115],"haemoglobin,":[89,116],"TBARS":[91,117],"glycogen":[93],"levels":[94],"were":[95,122],"estimated":[96],"Glibenclamide":[102],"used":[104],"a":[106],"standard":[107],"drug.":[108],"elevated":[110],"observed":[118],"rats":[121],"significantly":[123],"altered":[124],"compared":[125],"but":[128],"it":[129,148],"not":[130],"come":[131],"normal":[133],"after":[135],"treatment":[136],"with":[137],"for":[139],"15":[140],"days":[141],"From":[145],"results":[147],"suggest":[149],"that":[150],"ethanolic":[152],"of\u00a0M.":[154,183],"koenigii\u00a0possessed":[155],"potent":[156],"properties":[158],"may":[160],"be":[161],"due":[162,187],"presence":[165,190],"biological":[167],"active":[168],"ingredient":[169],"such":[170],"carbazole":[172],"alkaloids,":[173],"glycoside,":[174],"triterpenoids":[175],"phenolic":[177],"compounds.":[178],"antidiabetic":[181],"activity":[182],"probably":[186],"property.\r\n\r\n\t\u00a0\r\n\r\n\tKey":[194],"words:\u00a0Diabetes":[195],"mellitus,\u00a0Murraya":[196],"koenigii,\u00a0antioxidant.":[197]},"counts_by_year":[{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2020,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":6}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}