{"id":"https://openalex.org/W2108905802","doi":"https://doi.org/10.1128/aac.44.6.1701-1704.2000","title":"Characterization of a Mycobacterium smegmatis Mutant That Is Simultaneously Resistant to d -Cycloserine and Vancomycin","display_name":"Characterization of a Mycobacterium smegmatis Mutant That Is Simultaneously Resistant to d -Cycloserine and Vancomycin","publication_year":2000,"publication_date":"2000-06-01","ids":{"openalex":"https://openalex.org/W2108905802","doi":"https://doi.org/10.1128/aac.44.6.1701-1704.2000","mag":"2108905802","pmid":"https://pubmed.ncbi.nlm.nih.gov/10817733","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/89937"},"language":"en","primary_location":{"id":"doi:10.1128/aac.44.6.1701-1704.2000","doi":"https://doi.org/10.1128/aac.44.6.1701-1704.2000","is_oa":false,"landing_page_url":"https://doi.org/10.1128/aac.44.6.1701-1704.2000","pdf_url":null,"source":{"id":"https://openalex.org/S47215897","display_name":"Antimicrobial Agents and Chemotherapy","issn_l":"0066-4804","issn":["0066-4804","1070-6283","1098-6596"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Antimicrobial Agents and Chemotherapy","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/89937","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5004844433","display_name":"Marcy Peteroy","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4402554120","display_name":"Rutgers New Jersey Medical School","ror":"https://ror.org/014ye1258","country_code":"US","type":"education","lineage":["https://openalex.org/I102322142","https://openalex.org/I4390039302","https://openalex.org/I4402554120"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Marcy Peteroy","raw_affiliation_strings":["<!--label omitted: 1-->Department of Microbiology and Molecular Genetics1 and","<!--label omitted: 2-->National Tuberculosis Center,2 Department of Medicine, UMDNJ/New Jersey Medical School, Newark, New Jersey 07103-2714;","Department of Microbiology and Molecular Genetics1 and","National Tuberculosis Center,2 Department of Medicine, UMDNJ/New Jersey Medical School, Newark, New Jersey 07103-2714;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"<!--label omitted: 1-->Department of Microbiology and Molecular Genetics1 and","institution_ids":[]},{"raw_affiliation_string":"<!--label omitted: 2-->National Tuberculosis Center,2 Department of Medicine, UMDNJ/New Jersey Medical School, Newark, New Jersey 07103-2714;","institution_ids":["https://openalex.org/I4402554120"]},{"raw_affiliation_string":"Department of Microbiology and Molecular Genetics1 and","institution_ids":[]},{"raw_affiliation_string":"National Tuberculosis Center,2 Department of Medicine, UMDNJ/New Jersey Medical School, Newark, New Jersey 07103-2714;","institution_ids":["https://openalex.org/I4402554120"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110101678","display_name":"Anatoly I. Severin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4403928396","display_name":"Wyeth","ror":"https://ror.org/035j24j42","country_code":"US","type":"company","lineage":["https://openalex.org/I180857899","https://openalex.org/I4403928396"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Anatoly Severin","raw_affiliation_strings":["<!--label omitted: 3-->Wyeth-Ayerst Research, Department of Infectious Disease, Pearl River, New York 109653;","Wyeth-Ayerst Research, Department of Infectious Disease, Pearl River, New York 109653;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"<!--label omitted: 3-->Wyeth-Ayerst Research, Department of Infectious Disease, Pearl River, New York 109653;","institution_ids":[]},{"raw_affiliation_string":"Wyeth-Ayerst Research, Department of Infectious Disease, Pearl River, New York 109653;","institution_ids":["https://openalex.org/I4403928396"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013456495","display_name":"Frances Zhao","orcid":"https://orcid.org/0000-0001-5924-987X","observed_orcids":["https://orcid.org/0000-0001-5924-987X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Frances Zhao","raw_affiliation_strings":["<!--label omitted: 1-->Department of Microbiology and Molecular Genetics1 and","Department of Microbiology and Molecular Genetics1 and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"<!--label omitted: 1-->Department of Microbiology and Molecular Genetics1 and","institution_ids":[]},{"raw_affiliation_string":"Department of Microbiology and Molecular Genetics1 and","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"Dalya Rosner","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Dalya Rosner","raw_affiliation_strings":["<!--label omitted: 1-->Department of Microbiology and Molecular Genetics1 and","Department of Microbiology and Molecular Genetics1 and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"<!--label omitted: 1-->Department of Microbiology and Molecular Genetics1 and","institution_ids":[]},{"raw_affiliation_string":"Department of Microbiology and Molecular Genetics1 and","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007895046","display_name":"Uri A. Lopatin","orcid":"https://orcid.org/0000-0002-9544-0492","observed_orcids":["https://orcid.org/0000-0002-9544-0492"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Uri Lopatin","raw_affiliation_strings":["<!--label omitted: 1-->Department of Microbiology and Molecular Genetics1 and","Department of Microbiology and Molecular Genetics1 and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"<!--label omitted: 1-->Department of Microbiology and Molecular Genetics1 and","institution_ids":[]},{"raw_affiliation_string":"Department of Microbiology and Molecular Genetics1 and","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010720436","display_name":"Hataichanouk Scherman","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I92446798","display_name":"Colorado State University","ror":"https://ror.org/03k1gpj17","country_code":"US","type":"education","lineage":["https://openalex.org/I92446798"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hataichanouk Scherman","raw_affiliation_strings":["<!--label omitted: 4-->Department of Microbiology, Colorado State University, Fort Collins, Colorado 80523-16774; and","Department of Microbiology, Colorado State University, Fort Collins, Colorado 80523-16774; and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"<!--label omitted: 4-->Department of Microbiology, Colorado State University, Fort Collins, Colorado 80523-16774; and","institution_ids":["https://openalex.org/I92446798"]},{"raw_affiliation_string":"Department of Microbiology, Colorado State University, Fort Collins, Colorado 80523-16774; and","institution_ids":["https://openalex.org/I92446798"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064429548","display_name":"Aimee E. Belanger","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Aimee Belanger","raw_affiliation_strings":["<!--label omitted: 5-->Department of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania 152605","Department of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania 152605"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"<!--label omitted: 5-->Department of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania 152605","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"Department of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania 152605","institution_ids":["https://openalex.org/I170201317"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050301543","display_name":"Bohdan P. Harvey","orcid":"https://orcid.org/0000-0001-8193-9340","observed_orcids":["https://orcid.org/0000-0001-8193-9340"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Bohdan Harvey","raw_affiliation_strings":["<!--label omitted: 1-->Department of Microbiology and Molecular Genetics1 and","Department of Microbiology and Molecular Genetics1 and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"<!--label omitted: 1-->Department of Microbiology and Molecular Genetics1 and","institution_ids":[]},{"raw_affiliation_string":"Department of Microbiology and Molecular Genetics1 and","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064400315","display_name":"Graham F. Hatfull","orcid":"https://orcid.org/0000-0002-6705-6821","observed_orcids":["https://orcid.org/0000-0002-6705-6821"]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Graham F. Hatfull","raw_affiliation_strings":["<!--label omitted: 5-->Department of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania 152605","Department of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania 152605"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"<!--label omitted: 5-->Department of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania 152605","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"Department of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania 152605","institution_ids":["https://openalex.org/I170201317"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012975065","display_name":"Patrick Joseph Brennan","orcid":"https://orcid.org/0000-0001-6935-7057","observed_orcids":["https://orcid.org/0000-0001-6935-7057"]},"institutions":[{"id":"https://openalex.org/I92446798","display_name":"Colorado State University","ror":"https://ror.org/03k1gpj17","country_code":"US","type":"education","lineage":["https://openalex.org/I92446798"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Patrick J. Brennan","raw_affiliation_strings":["<!--label omitted: 4-->Department of Microbiology, Colorado State University, Fort Collins, Colorado 80523-16774; and","Department of Microbiology, Colorado State University, Fort Collins, Colorado 80523-16774; and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"<!--label omitted: 4-->Department of Microbiology, Colorado State University, Fort Collins, Colorado 80523-16774; and","institution_ids":["https://openalex.org/I92446798"]},{"raw_affiliation_string":"Department of Microbiology, Colorado State University, Fort Collins, Colorado 80523-16774; and","institution_ids":["https://openalex.org/I92446798"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5050607880","display_name":"Nancy D Connell","orcid":"https://orcid.org/0000-0003-0489-3777","observed_orcids":["https://orcid.org/0000-0003-0489-3777"]},"institutions":[{"id":"https://openalex.org/I4402554120","display_name":"Rutgers New Jersey Medical School","ror":"https://ror.org/014ye1258","country_code":"US","type":"education","lineage":["https://openalex.org/I102322142","https://openalex.org/I4390039302","https://openalex.org/I4402554120"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nancy D. Connell","raw_affiliation_strings":["<!--label omitted: 1-->Department of Microbiology and Molecular Genetics1 and","<!--label omitted: 2-->National Tuberculosis Center,2 Department of Medicine, UMDNJ/New Jersey Medical School, Newark, New Jersey 07103-2714;","Department of Microbiology and Molecular Genetics1 and","National Tuberculosis Center,2 Department of Medicine, UMDNJ/New Jersey Medical School, Newark, New Jersey 07103-2714;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"<!--label omitted: 1-->Department of Microbiology and Molecular Genetics1 and","institution_ids":[]},{"raw_affiliation_string":"<!--label omitted: 2-->National Tuberculosis Center,2 Department of Medicine, UMDNJ/New Jersey Medical School, Newark, New Jersey 07103-2714;","institution_ids":["https://openalex.org/I4402554120"]},{"raw_affiliation_string":"Department of Microbiology and Molecular Genetics1 and","institution_ids":[]},{"raw_affiliation_string":"National Tuberculosis Center,2 Department of Medicine, UMDNJ/New Jersey Medical School, Newark, New Jersey 07103-2714;","institution_ids":["https://openalex.org/I4402554120"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.5208,"has_fulltext":false,"cited_by_count":20,"citation_normalized_percentile":{"value":0.70461187,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"44","issue":"6","first_page":"1701","last_page":"1704"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10038","display_name":"Tuberculosis Research and Epidemiology","score":0.454800009727478,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10038","display_name":"Tuberculosis Research and Epidemiology","score":0.454800009727478,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10120","display_name":"Bacterial Genetics and Biotechnology","score":0.2168000042438507,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10147","display_name":"Antibiotic Resistance in Bacteria","score":0.13779999315738678,"subfield":{"id":"https://openalex.org/subfields/1313","display_name":"Molecular Medicine"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mycobacterium-smegmatis","display_name":"Mycobacterium smegmatis","score":0.9980000257492065},{"id":"https://openalex.org/keywords/vancomycin-resistance","display_name":"vancomycin resistance","score":1.0},{"id":"https://openalex.org/keywords/multidrug-resistance","display_name":"multidrug resistance","score":0.6940000057220459},{"id":"https://openalex.org/keywords/genetic-complementation","display_name":"gene complementation","score":0.9210000038146973},{"id":"https://openalex.org/keywords/cell-surface","display_name":"cell surface","score":0.6980000138282776},{"id":"https://openalex.org/keywords/antibiotic-resistance-mechanisms","display_name":"antibiotic resistance mechanisms","score":0.4970000088214874}],"concepts":[{"id":"https://openalex.org/C2777204207","wikidata":"https://www.wikidata.org/wiki/Q606230","display_name":"Mycobacterium smegmatis","level":4,"score":0.9353557825088501},{"id":"https://openalex.org/C2781122200","wikidata":"https://www.wikidata.org/wiki/Q418508","display_name":"Cycloserine","level":3,"score":0.848293125629425},{"id":"https://openalex.org/C188082640","wikidata":"https://www.wikidata.org/wiki/Q1780899","display_name":"Complementation","level":4,"score":0.8425209522247314},{"id":"https://openalex.org/C143065580","wikidata":"https://www.wikidata.org/wiki/Q3285695","display_name":"Mutant","level":3,"score":0.8223803043365479},{"id":"https://openalex.org/C2778980435","wikidata":"https://www.wikidata.org/wiki/Q424027","display_name":"Vancomycin","level":4,"score":0.7272861003875732},{"id":"https://openalex.org/C2776634448","wikidata":"https://www.wikidata.org/wiki/Q206920","display_name":"Peptidoglycan","level":3,"score":0.6567541360855103},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.5842294692993164},{"id":"https://openalex.org/C2777975735","wikidata":"https://www.wikidata.org/wiki/Q130971","display_name":"Mycobacterium tuberculosis","level":3,"score":0.4598335921764374},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4155261516571045},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3951401114463806},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.3168564736843109},{"id":"https://openalex.org/C501593827","wikidata":"https://www.wikidata.org/wiki/Q12187","display_name":"Antibiotics","level":2,"score":0.21819382905960083},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.20119544863700867},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.1972627341747284},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0987374484539032},{"id":"https://openalex.org/C2781069245","wikidata":"https://www.wikidata.org/wiki/Q12204","display_name":"Tuberculosis","level":2,"score":0.07594943046569824},{"id":"https://openalex.org/C2779489039","wikidata":"https://www.wikidata.org/wiki/Q188121","display_name":"Staphylococcus aureus","level":3,"score":0.07084274291992188},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003523","descriptor_name":"Cycloserine","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D004352","descriptor_name":"Drug Resistance, Microbial","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014640","descriptor_name":"Vancomycin","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D016415","descriptor_name":"Sequence Alignment","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020102","descriptor_name":"Mycobacterium smegmatis","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D020102","descriptor_name":"Mycobacterium smegmatis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D020713","descriptor_name":"Vancomycin Resistance","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1128/aac.44.6.1701-1704.2000","doi":"https://doi.org/10.1128/aac.44.6.1701-1704.2000","is_oa":false,"landing_page_url":"https://doi.org/10.1128/aac.44.6.1701-1704.2000","pdf_url":null,"source":{"id":"https://openalex.org/S47215897","display_name":"Antimicrobial Agents and Chemotherapy","issn_l":"0066-4804","issn":["0066-4804","1070-6283","1098-6596"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Antimicrobial Agents and Chemotherapy","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:89937","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/89937","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Antimicrob Agents Chemother","raw_type":"Text"},{"id":"pmid:10817733","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10817733","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Antimicrobial agents and chemotherapy","raw_type":"Journal Article"},{"id":"pmh:oai:d-scholarship.pitt.edu:16637","doi":null,"is_oa":false,"landing_page_url":"https://d-scholarship.pitt.edu/16637/1/licence.txt","pdf_url":null,"source":{"id":"https://openalex.org/S4306402372","display_name":"D-Scholarship@Pitt (University of Pittsburgh)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I170201317","host_organization_name":"University of Pittsburgh","host_organization_lineage":["https://openalex.org/I170201317"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Article"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:89937","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/89937","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Antimicrob Agents Chemother","raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.8371999859809875}],"study_designs":[],"awards":[{"id":"https://openalex.org/G7390716806","display_name":"NUTRIENT TRANSPORT MECHANISMS IN MYCOBACTERIA","funder_award_id":"R29AI034436","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"}],"funders":[{"id":"https://openalex.org/F4320337355","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":17,"referenced_works":["https://openalex.org/W1512810258","https://openalex.org/W1572173025","https://openalex.org/W1879326539","https://openalex.org/W1942872363","https://openalex.org/W1975045527","https://openalex.org/W2011635923","https://openalex.org/W2025433783","https://openalex.org/W2035234659","https://openalex.org/W2053991753","https://openalex.org/W2074968287","https://openalex.org/W2090433956","https://openalex.org/W2123339235","https://openalex.org/W2131921806","https://openalex.org/W2138950134","https://openalex.org/W2155222297","https://openalex.org/W2169638198","https://openalex.org/W2418642921"],"related_works":["https://openalex.org/W2124564317","https://openalex.org/W2162983487","https://openalex.org/W2155222297","https://openalex.org/W7100037211","https://openalex.org/W2159607805","https://openalex.org/W2030376870","https://openalex.org/W2022816332","https://openalex.org/W3015503156","https://openalex.org/W3023110812","https://openalex.org/W4247954410"],"abstract_inverted_index":{"A":[0],"mutant":[1,36],"of":[2],"Mycobacterium":[3],"smegmatis":[4],"has":[5],"been":[6],"isolated":[7],"that":[8],"is":[9,37],"simultaneously":[10],"resistant":[11],"to":[12,26,30,41],"both":[13,27],"D-cycloserine":[14],"(D-CS)":[15],"and":[16,32],"vancomycin.":[17],"Genetic":[18],"complementation":[19],"with":[20],"a":[21,42],"PBP4":[22],"homolog":[23],"restores":[24],"sensitivity":[25],"drugs.":[28],"Resistance":[29],"D-CS":[31],"vancomycin":[33],"in":[34],"this":[35],"most":[38],"likely":[39],"due":[40],"novel":[43],"mechanism":[44],"involving":[45],"peptidoglycan":[46],"assembly":[47],"at":[48],"the":[49],"cell":[50],"surface.":[51]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-01T11:40:01.658920","created_date":"2016-06-24T00:00:00"}