{"id":"https://openalex.org/W2108845535","doi":null,"title":"Uso de tacrolimus en pediatr\u00eda","display_name":"Uso de tacrolimus en pediatr\u00eda","publication_year":2006,"publication_date":"2006-08-01","ids":{"openalex":"https://openalex.org/W2108845535","mag":"2108845535"},"language":"es","primary_location":{"id":"pmh:oai:bibmed.ucla.edu.ve:T070000064383/10","doi":null,"is_oa":false,"landing_page_url":"http://bibmed.ucla.edu.ve/cgi-win/be_alex.exe?Acceso=T070000064383/10&Nombrebd=bmucla","pdf_url":null,"source":{"id":"https://openalex.org/S7407064131","display_name":"UCLA - Biblioteca de Ciencias de la Salud","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I19325673","host_organization_name":"Universidad Centroccidental Lisandro Alvarado","host_organization_lineage":["https://openalex.org/I19325673"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5028069402","display_name":"C. Herlinda Reyes-Perez","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210097267","display_name":"Hospital Infantil de M\u00e9xico Federico G\u00f3mez","ror":"https://ror.org/00nzavp26","country_code":"MX","type":"healthcare","lineage":["https://openalex.org/I4210097267"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"C. Herlinda Reyes-Perez","raw_affiliation_strings":["Hospital Infantil de M\u00e9xico Federico G\u00f3mez"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hospital Infantil de M\u00e9xico Federico G\u00f3mez","institution_ids":["https://openalex.org/I4210097267"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5017027517","display_name":"Mara Medeiros-Domingo","orcid":"https://orcid.org/0000-0002-6848-8933","observed_orcids":["https://orcid.org/0000-0002-6848-8933"]},"institutions":[{"id":"https://openalex.org/I4210097267","display_name":"Hospital Infantil de M\u00e9xico Federico G\u00f3mez","ror":"https://ror.org/00nzavp26","country_code":"MX","type":"healthcare","lineage":["https://openalex.org/I4210097267"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Mara Medeiros-Domingo","raw_affiliation_strings":["Hospital Infantil de M\u00e9xico Federico G\u00f3mez, M\u00e9xico, M\u00e9xico"],"raw_orcid":"https://orcid.org/0000-0002-6848-8933","affiliations":[{"raw_affiliation_string":"Hospital Infantil de M\u00e9xico Federico G\u00f3mez, M\u00e9xico, M\u00e9xico","institution_ids":["https://openalex.org/I4210097267"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I4210097267"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"63","issue":"4","first_page":"276","last_page":"285"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10373","display_name":"Renal Transplantation Outcomes and Treatments","score":0.9574999809265137,"subfield":{"id":"https://openalex.org/subfields/2747","display_name":"Transplantation"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10373","display_name":"Renal Transplantation Outcomes and Treatments","score":0.9574999809265137,"subfield":{"id":"https://openalex.org/subfields/2747","display_name":"Transplantation"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12547","display_name":"Pharmaceutical studies and practices","score":0.005799999926239252,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T14072","display_name":"Immunotoxicology and immune responses","score":0.004399999976158142,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/tacrolimus","display_name":"tacrolimus","score":1.0},{"id":"https://openalex.org/keywords/pediatric-patients","display_name":"pediatric patients","score":0.7089999914169312},{"id":"https://openalex.org/keywords/calcineurin-inhibitors","display_name":"calcineurin inhibitors","score":0.9020000100135803},{"id":"https://openalex.org/keywords/immunosuppressive-therapy","display_name":"immunosuppressive therapy","score":0.8980000019073486},{"id":"https://openalex.org/keywords/nephrotic-syndrome","display_name":"nephrotic syndrome","score":0.8539999723434448},{"id":"https://openalex.org/keywords/systemic-lupus-erythematosus","display_name":"systemic lupus erythematosus","score":1.0},{"id":"https://openalex.org/keywords/atopic-dermatitis","display_name":"atopic dermatitis","score":0.9559999704360962},{"id":"https://openalex.org/keywords/vitiligo","display_name":"vitiligo","score":0.9990000128746033},{"id":"https://openalex.org/keywords/psoriasis","display_name":"psoriasis","score":0.9909999966621399},{"id":"https://openalex.org/keywords/pharmacokinetics","display_name":"pharmacokinetics","score":0.9980000257492065},{"id":"https://openalex.org/keywords/therapeutic-drug-monitoring","display_name":"therapeutic drug monitoring","score":0.9789999723434448},{"id":"https://openalex.org/keywords/adverse-effects","display_name":"adverse effects","score":0.7549999952316284},{"id":"https://openalex.org/keywords/drug-toxicity","display_name":"drug toxicity","score":0.7879999876022339}],"concepts":[{"id":"https://openalex.org/C15708023","wikidata":"https://www.wikidata.org/wiki/Q80083","display_name":"Humanities","level":1,"score":0.7349056005477905},{"id":"https://openalex.org/C2909675724","wikidata":"https://www.wikidata.org/wiki/Q411648","display_name":"Tacrolimus","level":3,"score":0.43428581953048706},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.41800999641418457},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.3789278566837311},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.038131505250930786},{"id":"https://openalex.org/C2911091166","wikidata":"https://www.wikidata.org/wiki/Q106419912","display_name":"Transplantation","level":2,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:bibmed.ucla.edu.ve:T070000064383/10","doi":null,"is_oa":false,"landing_page_url":"http://bibmed.ucla.edu.ve/cgi-win/be_alex.exe?Acceso=T070000064383/10&Nombrebd=bmucla","pdf_url":null,"source":{"id":"https://openalex.org/S7407064131","display_name":"UCLA - Biblioteca de Ciencias de la Salud","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I19325673","host_organization_name":"Universidad Centroccidental Lisandro Alvarado","host_organization_lineage":["https://openalex.org/I19325673"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},{"id":"mag:2108845535","doi":null,"is_oa":false,"landing_page_url":"https://www.medigraphic.com/pdfs/bmhim/hi-2006/hi064j.pdf","pdf_url":null,"source":{"id":"https://openalex.org/S2755767643","display_name":"Bolet\u00edn M\u00e9dico del Hospital Infantil de M\u00e9xico","issn_l":"0539-6115","issn":["0539-6115","1665-1146"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","medline","poland-40","russia-white-list-3","scielo"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Bolet\u00edn M\u00e9dico del Hospital Infantil de M\u00e9xico","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.98580002784729}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":72,"referenced_works":["https://openalex.org/W143318074","https://openalex.org/W145838624","https://openalex.org/W190125070","https://openalex.org/W1791766647","https://openalex.org/W1964034039","https://openalex.org/W1964887178","https://openalex.org/W1965970672","https://openalex.org/W1970924247","https://openalex.org/W1971361422","https://openalex.org/W1976220632","https://openalex.org/W1978952701","https://openalex.org/W1979262437","https://openalex.org/W1983749952","https://openalex.org/W1984346081","https://openalex.org/W1989119018","https://openalex.org/W1989192303","https://openalex.org/W1989399809","https://openalex.org/W1991992414","https://openalex.org/W1994039429","https://openalex.org/W1998131880","https://openalex.org/W2003213520","https://openalex.org/W2005328285","https://openalex.org/W2005948180","https://openalex.org/W2008423993","https://openalex.org/W2014571455","https://openalex.org/W2019431336","https://openalex.org/W2021847562","https://openalex.org/W2025752875","https://openalex.org/W2026257770","https://openalex.org/W2026360416","https://openalex.org/W2027470528","https://openalex.org/W2027774666","https://openalex.org/W2030666199","https://openalex.org/W2031138441","https://openalex.org/W2034233121","https://openalex.org/W2039643365","https://openalex.org/W2040830959","https://openalex.org/W2041961159","https://openalex.org/W2045109635","https://openalex.org/W2048441131","https://openalex.org/W2053939166","https://openalex.org/W2054580848","https://openalex.org/W2061945577","https://openalex.org/W2063916522","https://openalex.org/W2068650301","https://openalex.org/W2072295877","https://openalex.org/W2075845550","https://openalex.org/W2077799768","https://openalex.org/W2079817496","https://openalex.org/W2080483086","https://openalex.org/W2085067466","https://openalex.org/W2085516037","https://openalex.org/W2086502379","https://openalex.org/W2086575226","https://openalex.org/W2090636148","https://openalex.org/W2109917792","https://openalex.org/W2110144111","https://openalex.org/W2118111820","https://openalex.org/W2122527560","https://openalex.org/W2126811958","https://openalex.org/W2129827777","https://openalex.org/W2134477893","https://openalex.org/W2135731448","https://openalex.org/W2138407553","https://openalex.org/W2140196022","https://openalex.org/W2140576929","https://openalex.org/W2149818303","https://openalex.org/W2153323664","https://openalex.org/W2156558246","https://openalex.org/W2324012345","https://openalex.org/W2433111185","https://openalex.org/W2768259672"],"related_works":["https://openalex.org/W2184554247","https://openalex.org/W1173819154","https://openalex.org/W4255112549","https://openalex.org/W1980404865","https://openalex.org/W2936789576","https://openalex.org/W2016553001","https://openalex.org/W2375762500","https://openalex.org/W2028169376","https://openalex.org/W4250630385","https://openalex.org/W2052085261"],"abstract_inverted_index":{"El":[0],"tacrolimus":[1,62],"es":[2],"un":[3],"farmaco":[4],"inmunosupresor":[5,22],"inhibidor":[6],"de":[7,15,23,29],"calcineurina":[8],"utilizado":[9],"principalmente":[10],"para":[11],"prevenir":[12],"el":[13],"rechazo":[14],"organos":[16],"solidos.":[17],"Tambien":[18],"se":[19,51],"emplea":[20],"como":[21],"segunda":[24],"linea":[25],"en":[26,63,68,71],"otras":[27],"enfermedades":[28],"origen":[30],"inmunologico":[31],"entre":[32,46],"las":[33],"que":[34,73],"destacan:":[35],"sindrome":[36],"nefrotico,":[37],"lupus":[38],"eritematoso":[39],"sistemico,":[40],"dermatitis":[41],"atopica,":[42],"vitiligo":[43],"y":[44,59],"psoriasis":[45],"otras.":[47],"En":[48],"este":[49],"articulo":[50],"revisa":[52],"la":[53],"farmacocinetica,":[54],"monitoreo":[55],"terapeutico,":[56],"efectos":[57],"adversos":[58],"toxicidad":[60],"del":[61],"pacientes":[64],"pediatricos,":[65],"haciendo":[66],"enfasis":[67],"los":[69,72],"padecimientos":[70],"ha":[74],"demostrado":[75],"utilidad.":[76]},"counts_by_year":[{"year":2013,"cited_by_count":1}],"updated_date":"2026-11-05T12:25:35.769452","created_date":"2016-06-24T00:00:00"}