{"id":"https://openalex.org/W2108746111","doi":"https://doi.org/10.3389/fpsyg.2015.01569","title":"Genetic influences on insight problem solving: the role of catechol-O-methyltransferase (COMT) gene polymorphisms","display_name":"Genetic influences on insight problem solving: the role of catechol-O-methyltransferase (COMT) gene polymorphisms","publication_year":2015,"publication_date":"2015-10-13","ids":{"openalex":"https://openalex.org/W2108746111","doi":"https://doi.org/10.3389/fpsyg.2015.01569","mag":"2108746111","pmid":"https://pubmed.ncbi.nlm.nih.gov/26528222","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4602104"},"language":"en","primary_location":{"id":"doi:10.3389/fpsyg.2015.01569","doi":"https://doi.org/10.3389/fpsyg.2015.01569","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fpsyg.2015.01569","pdf_url":"https://www.frontiersin.org/articles/10.3389/fpsyg.2015.01569/pdf","source":{"id":"https://openalex.org/S9692511","display_name":"Frontiers in Psychology","issn_l":"1664-1078","issn":["1664-1078"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","erih-plus","jufo-1","ki-jl-1","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Psychology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","datacite","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.frontiersin.org/articles/10.3389/fpsyg.2015.01569/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Weili Jiang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I20231570","display_name":"Peking University","ror":"https://ror.org/02v51f717","country_code":"CN","type":"education","lineage":["https://openalex.org/I20231570"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Weili Jiang","raw_affiliation_strings":["Department of Psychology and Beijing Key Laboratory of Behavior and Mental Health, Peking University, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychology and Beijing Key Laboratory of Behavior and Mental Health, Peking University, Beijing, China","institution_ids":["https://openalex.org/I20231570"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112652496","display_name":"Siyuan Shang","orcid":"https://orcid.org/0009-0001-2114-1326","observed_orcids":["https://orcid.org/0009-0001-2114-1326"]},"institutions":[{"id":"https://openalex.org/I20231570","display_name":"Peking University","ror":"https://ror.org/02v51f717","country_code":"CN","type":"education","lineage":["https://openalex.org/I20231570"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Siyuan Shang","raw_affiliation_strings":["Department of Psychology and Beijing Key Laboratory of Behavior and Mental Health, Peking University, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychology and Beijing Key Laboratory of Behavior and Mental Health, Peking University, Beijing, China","institution_ids":["https://openalex.org/I20231570"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5064821749","display_name":"Yanjie Su","orcid":"https://orcid.org/0000-0003-3508-8674","observed_orcids":["https://orcid.org/0000-0003-3508-8674"]},"institutions":[{"id":"https://openalex.org/I20231570","display_name":"Peking University","ror":"https://ror.org/02v51f717","country_code":"CN","type":"education","lineage":["https://openalex.org/I20231570"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Yanjie Su","raw_affiliation_strings":["Department of Psychology and Beijing Key Laboratory of Behavior and Mental Health, Peking University, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychology and Beijing Key Laboratory of Behavior and Mental Health, Peking University, Beijing, China","institution_ids":["https://openalex.org/I20231570"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5064821749"],"corresponding_institution_ids":["https://openalex.org/I20231570"],"apc_list":{"value":3150,"currency":"CHF","value_usd":3801},"apc_paid":{"value":3150,"currency":"CHF","value_usd":3801},"fwci":4.0612,"has_fulltext":true,"cited_by_count":33,"citation_normalized_percentile":{"value":0.92893334,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"6","issue":null,"first_page":"1569","last_page":"1569"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11079","display_name":"Creativity in Education and Neuroscience","score":0.9320999979972839,"subfield":{"id":"https://openalex.org/subfields/3205","display_name":"Experimental and Cognitive Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},"topics":[{"id":"https://openalex.org/T11079","display_name":"Creativity in Education and Neuroscience","score":0.9320999979972839,"subfield":{"id":"https://openalex.org/subfields/3205","display_name":"Experimental and Cognitive Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T10056","display_name":"Neurotransmitter Receptor Influence on Behavior","score":0.03929999843239784,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.008700000122189522,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/insight-problem-solving","display_name":"insight problem solving","score":0.9990000128746033},{"id":"https://openalex.org/keywords/catechol-o-methyltransferase","display_name":"catechol-O-methyltransferase","score":0.9570000171661377},{"id":"https://openalex.org/keywords/comt-gene","display_name":"COMT gene","score":0.921999990940094},{"id":"https://openalex.org/keywords/single-nucleotide-polymorphisms","display_name":"single nucleotide polymorphisms","score":0.9900000095367432},{"id":"https://openalex.org/keywords/gender-differences","display_name":"gender differences","score":0.6439999938011169},{"id":"https://openalex.org/keywords/comt-val158met-polymorphism","display_name":"COMT Val158Met polymorphism","score":0.906000018119812},{"id":"https://openalex.org/keywords/aha-moments","display_name":"aha moments","score":0.6850000023841858},{"id":"https://openalex.org/keywords/catecholamines","display_name":"catecholamines","score":0.8360000252723694}],"concepts":[{"id":"https://openalex.org/C2778524067","wikidata":"https://www.wikidata.org/wiki/Q17142059","display_name":"rs4680","level":5,"score":0.9816024303436279},{"id":"https://openalex.org/C185361966","wikidata":"https://www.wikidata.org/wiki/Q94291140","display_name":"Catechol-O-methyl transferase","level":4,"score":0.8702804446220398},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.5648643970489502},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.5612847805023193},{"id":"https://openalex.org/C180754005","wikidata":"https://www.wikidata.org/wiki/Q80726","display_name":"Allele","level":3,"score":0.5037652850151062},{"id":"https://openalex.org/C153209595","wikidata":"https://www.wikidata.org/wiki/Q501128","display_name":"Single-nucleotide polymorphism","level":4,"score":0.4601834714412689},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.4354850947856903},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.32816118001937866},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.15086302161216736}],"mesh":[],"locations_count":7,"locations":[{"id":"doi:10.3389/fpsyg.2015.01569","doi":"https://doi.org/10.3389/fpsyg.2015.01569","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fpsyg.2015.01569","pdf_url":"https://www.frontiersin.org/articles/10.3389/fpsyg.2015.01569/pdf","source":{"id":"https://openalex.org/S9692511","display_name":"Frontiers in Psychology","issn_l":"1664-1078","issn":["1664-1078"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","erih-plus","jufo-1","ki-jl-1","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Psychology","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:3604380","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4602104","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmid:26528222","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/26528222","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in psychology","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:4602104","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC4602104/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Front Psychol","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:ad5d00f5438947a0b53a0b909a327bf2","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/ad5d00f5438947a0b53a0b909a327bf2","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Frontiers in Psychology, Vol 6 (2015)","raw_type":"article"},{"id":"doi:10.60692/4dkjz-sqq94","doi":"https://doi.org/10.60692/4dkjz-sqq94","is_oa":true,"landing_page_url":"https://doi.org/10.60692/4dkjz-sqq94","pdf_url":null,"source":{"id":"https://openalex.org/S7407051682","display_name":"Greater South Information System","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article-journal"},{"id":"doi:10.60692/7k3tn-jk115","doi":"https://doi.org/10.60692/7k3tn-jk115","is_oa":true,"landing_page_url":"https://doi.org/10.60692/7k3tn-jk115","pdf_url":null,"source":{"id":"https://openalex.org/S7407051682","display_name":"Greater South Information System","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article-journal"}],"best_oa_location":{"id":"doi:10.3389/fpsyg.2015.01569","doi":"https://doi.org/10.3389/fpsyg.2015.01569","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fpsyg.2015.01569","pdf_url":"https://www.frontiersin.org/articles/10.3389/fpsyg.2015.01569/pdf","source":{"id":"https://openalex.org/S9692511","display_name":"Frontiers in Psychology","issn_l":"1664-1078","issn":["1664-1078"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","erih-plus","jufo-1","ki-jl-1","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Psychology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.6240000128746033}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[{"id":"https://openalex.org/G179005647","display_name":"\u5171\u60c5\u4e24\u6210\u5206\u53d1\u5c55\u7684\u5fc3\u7406\u673a\u5236\uff1a\u5bb6\u5ead\u6559\u517b\u73af\u5883\u548c\u57fa\u56e0\u591a\u6001\u6027\u7684\u5171\u540c\u4f5c\u7528","funder_award_id":"31371040","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G543775419","display_name":null,"funder_award_id":"31170995","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G5924476998","display_name":null,"funder_award_id":"31571134","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2108746111.pdf","grobid_xml":"https://content.openalex.org/works/W2108746111.grobid-xml"},"referenced_works_count":59,"referenced_works":["https://openalex.org/W1499959058","https://openalex.org/W1512357812","https://openalex.org/W1966427346","https://openalex.org/W1969754328","https://openalex.org/W1971179664","https://openalex.org/W1973197709","https://openalex.org/W1979449422","https://openalex.org/W1982342057","https://openalex.org/W1983261488","https://openalex.org/W1996314002","https://openalex.org/W1997753459","https://openalex.org/W2002920339","https://openalex.org/W2003627105","https://openalex.org/W2003753278","https://openalex.org/W2011855964","https://openalex.org/W2011987775","https://openalex.org/W2013250252","https://openalex.org/W2018591558","https://openalex.org/W2021133623","https://openalex.org/W2024699871","https://openalex.org/W2028422459","https://openalex.org/W2030493818","https://openalex.org/W2032866243","https://openalex.org/W2035043103","https://openalex.org/W2035268471","https://openalex.org/W2038282880","https://openalex.org/W2049839400","https://openalex.org/W2050074375","https://openalex.org/W2052265523","https://openalex.org/W2054217820","https://openalex.org/W2054856852","https://openalex.org/W2060860789","https://openalex.org/W2061285076","https://openalex.org/W2070400779","https://openalex.org/W2071902433","https://openalex.org/W2076094898","https://openalex.org/W2076817195","https://openalex.org/W2078504022","https://openalex.org/W2086438570","https://openalex.org/W2087983258","https://openalex.org/W2094134651","https://openalex.org/W2094758440","https://openalex.org/W2100040984","https://openalex.org/W2104363283","https://openalex.org/W2112804921","https://openalex.org/W2115223032","https://openalex.org/W2118554553","https://openalex.org/W2119305161","https://openalex.org/W2122945950","https://openalex.org/W2127054206","https://openalex.org/W2132569582","https://openalex.org/W2137603333","https://openalex.org/W2140657757","https://openalex.org/W2151331628","https://openalex.org/W2167201634","https://openalex.org/W4212923520","https://openalex.org/W4242698167","https://openalex.org/W4250454983","https://openalex.org/W4256201318"],"related_works":["https://openalex.org/W2940258028","https://openalex.org/W2936916381","https://openalex.org/W2040107567","https://openalex.org/W2551895962","https://openalex.org/W7005790636","https://openalex.org/W7097973703","https://openalex.org/W2354230820","https://openalex.org/W2104523457","https://openalex.org/W2100040984","https://openalex.org/W2061006420"],"abstract_inverted_index":{"People":[0],"may":[1,28],"experience":[2,16],"an":[3],"\"aha\"":[4],"moment,":[5],"when":[6],"suddenly":[7],"realizing":[8],"a":[9,12],"solution":[10],"of":[11,82,87,108,129],"puzzling":[13],"problem.":[14],"This":[15,123],"is":[17,40],"called":[18],"insight":[19,31,67,93,109,118,134,150],"problem":[20,32,135,151],"solving.":[21,152],"Several":[22],"findings":[23],"suggest":[24],"that":[25,77,113,140,144],"catecholamine-related":[26],"genes":[27],"contribute":[29],"to":[30,52],"solving,":[33],"among":[34],"which":[35],"the":[36,41,54,63,97,126,130,142,145],"catechol-O-methyltransferase":[37],"(COMT)":[38],"gene":[39,65,99,115,147],"most":[42],"promising":[43],"candidate.":[44],"The":[45,74],"current":[46],"study":[47,124],"examined":[48],"753":[49],"healthy":[50],"individuals":[51,78],"determine":[53],"associations":[55],"between":[56],"7":[57],"candidate":[58],"single":[59],"nucleotide":[60],"polymorphisms":[61],"on":[62,92,133],"COMT":[64,98,146],"and":[66,96,137],"problem-solving":[68,94,119],"performance,":[69],"while":[70],"considering":[71],"gender":[72,103],"differences.":[73],"results":[75],"showed":[76],"carrying":[79],"A":[80],"allele":[81,86],"rs4680":[83],"or":[84],"T":[85],"rs4633":[88],"scored":[89],"significantly":[90],"higher":[91],"tasks,":[95],"rs5993883":[100],"combined":[101],"with":[102,105],"interacted":[104],"correct":[106],"solutions":[107],"problems,":[110],"specifically":[111],"showing":[112],"this":[114],"only":[116],"influenced":[117],"performance":[120],"in":[121,149],"males.":[122],"presents":[125],"first":[127],"investigation":[128],"genetic":[131],"impact":[132],"solving":[136],"provides":[138],"evidence":[139],"highlights":[141],"role":[143],"plays":[148]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":5},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":5},{"year":2018,"cited_by_count":11},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}