{"id":"https://openalex.org/W2108643149","doi":"https://doi.org/10.1007/s00280-014-2429-5","title":"A phase II trial of prolonged, continuous infusion of low-dose gemcitabine plus cisplatin in patients with advanced malignant pleural mesothelioma","display_name":"A phase II trial of prolonged, continuous infusion of low-dose gemcitabine plus cisplatin in patients with advanced malignant pleural mesothelioma","publication_year":2014,"publication_date":"2014-03-31","ids":{"openalex":"https://openalex.org/W2108643149","doi":"https://doi.org/10.1007/s00280-014-2429-5","mag":"2108643149","pmid":"https://pubmed.ncbi.nlm.nih.gov/24687408"},"language":"en","primary_location":{"id":"doi:10.1007/s00280-014-2429-5","doi":"https://doi.org/10.1007/s00280-014-2429-5","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s00280-014-2429-5","pdf_url":null,"source":{"id":"https://openalex.org/S117498271","display_name":"Cancer Chemotherapy and Pharmacology","issn_l":"0344-5704","issn":["0344-5704","1432-0843"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Chemotherapy and Pharmacology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5035063101","display_name":"Oscar G. Arrieta","orcid":"https://orcid.org/0000-0002-1164-3779","observed_orcids":["https://orcid.org/0000-0002-1164-3779"]},"institutions":[{"id":"https://openalex.org/I4210119015","display_name":"Instituto Nacional de Cancerolog\u00eda","ror":"https://ror.org/02hdnbe80","country_code":"CO","type":"healthcare","lineage":["https://openalex.org/I4210119015"]},{"id":"https://openalex.org/I4210153971","display_name":"Instituto Nacional de Cancerolog\u00eda","ror":"https://ror.org/04z3afh10","country_code":"MX","type":"government","lineage":["https://openalex.org/I4210095685","https://openalex.org/I4210153971"]}],"countries":["CO","MX"],"is_corresponding":true,"raw_author_name":"Oscar Arrieta","raw_affiliation_strings":["Thoracic Oncology Unit, Experimental Oncology Laboratory, Instituto Nacional de Cancerolog\u00eda (INCan), San Fernando # 22, Col. Secci\u00f3n XVI, Tlalpan, C.P. 14080, Mexico, D.F., Mexico, ogarrieta@gmail.com","Instituto Nacional de Cancerolog\u00eda (INCan)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Thoracic Oncology Unit, Experimental Oncology Laboratory, Instituto Nacional de Cancerolog\u00eda (INCan), San Fernando # 22, Col. Secci\u00f3n XVI, Tlalpan, C.P. 14080, Mexico, D.F., Mexico, ogarrieta@gmail.com","institution_ids":["https://openalex.org/I4210153971"]},{"raw_affiliation_string":"Instituto Nacional de Cancerolog\u00eda (INCan)","institution_ids":["https://openalex.org/I4210119015","https://openalex.org/I4210153971"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008515444","display_name":"Diego L\u00f3pez-Mac\u00edas","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210119015","display_name":"Instituto Nacional de Cancerolog\u00eda","ror":"https://ror.org/02hdnbe80","country_code":"CO","type":"healthcare","lineage":["https://openalex.org/I4210119015"]},{"id":"https://openalex.org/I4210153971","display_name":"Instituto Nacional de Cancerolog\u00eda","ror":"https://ror.org/04z3afh10","country_code":"MX","type":"government","lineage":["https://openalex.org/I4210095685","https://openalex.org/I4210153971"]}],"countries":["CO","MX"],"is_corresponding":false,"raw_author_name":"Diego L\u00f3pez-Mac\u00edas","raw_affiliation_strings":["Thoracic Oncology Unit, Experimental Oncology Laboratory, Instituto Nacional de Cancerolog\u00eda (INCan), San Fernando # 22, Col. Secci\u00f3n XVI, Tlalpan, C.P. 14080, Mexico, D.F., Mexico","Instituto Nacional de Cancerolog\u00eda (INCan)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Thoracic Oncology Unit, Experimental Oncology Laboratory, Instituto Nacional de Cancerolog\u00eda (INCan), San Fernando # 22, Col. Secci\u00f3n XVI, Tlalpan, C.P. 14080, Mexico, D.F., Mexico","institution_ids":["https://openalex.org/I4210153971"]},{"raw_affiliation_string":"Instituto Nacional de Cancerolog\u00eda (INCan)","institution_ids":["https://openalex.org/I4210119015","https://openalex.org/I4210153971"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112394910","display_name":"V\u00edctor Osvaldo Mendoza-Garc\u00eda","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210119015","display_name":"Instituto Nacional de Cancerolog\u00eda","ror":"https://ror.org/02hdnbe80","country_code":"CO","type":"healthcare","lineage":["https://openalex.org/I4210119015"]},{"id":"https://openalex.org/I4210153971","display_name":"Instituto Nacional de Cancerolog\u00eda","ror":"https://ror.org/04z3afh10","country_code":"MX","type":"government","lineage":["https://openalex.org/I4210095685","https://openalex.org/I4210153971"]}],"countries":["CO","MX"],"is_corresponding":false,"raw_author_name":"V\u00edctor-Osvaldo Mendoza-Garc\u00eda","raw_affiliation_strings":["Thoracic Oncology Unit, Experimental Oncology Laboratory, Instituto Nacional de Cancerolog\u00eda (INCan), San Fernando # 22, Col. Secci\u00f3n XVI, Tlalpan, C.P. 14080, Mexico, D.F., Mexico","Instituto Nacional de Cancerolog\u00eda (INCan)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Thoracic Oncology Unit, Experimental Oncology Laboratory, Instituto Nacional de Cancerolog\u00eda (INCan), San Fernando # 22, Col. Secci\u00f3n XVI, Tlalpan, C.P. 14080, Mexico, D.F., Mexico","institution_ids":["https://openalex.org/I4210153971"]},{"raw_affiliation_string":"Instituto Nacional de Cancerolog\u00eda (INCan)","institution_ids":["https://openalex.org/I4210119015","https://openalex.org/I4210153971"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054926040","display_name":"Ludwing Bacon-Fonseca","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210119015","display_name":"Instituto Nacional de Cancerolog\u00eda","ror":"https://ror.org/02hdnbe80","country_code":"CO","type":"healthcare","lineage":["https://openalex.org/I4210119015"]},{"id":"https://openalex.org/I4210153971","display_name":"Instituto Nacional de Cancerolog\u00eda","ror":"https://ror.org/04z3afh10","country_code":"MX","type":"government","lineage":["https://openalex.org/I4210095685","https://openalex.org/I4210153971"]}],"countries":["CO","MX"],"is_corresponding":false,"raw_author_name":"Ludwing Bacon-Fonseca","raw_affiliation_strings":["Thoracic Oncology Unit, Experimental Oncology Laboratory, Instituto Nacional de Cancerolog\u00eda (INCan), San Fernando # 22, Col. Secci\u00f3n XVI, Tlalpan, C.P. 14080, Mexico, D.F., Mexico","Instituto Nacional de Cancerolog\u00eda (INCan)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Thoracic Oncology Unit, Experimental Oncology Laboratory, Instituto Nacional de Cancerolog\u00eda (INCan), San Fernando # 22, Col. Secci\u00f3n XVI, Tlalpan, C.P. 14080, Mexico, D.F., Mexico","institution_ids":["https://openalex.org/I4210153971"]},{"raw_affiliation_string":"Instituto Nacional de Cancerolog\u00eda (INCan)","institution_ids":["https://openalex.org/I4210119015","https://openalex.org/I4210153971"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058226044","display_name":"Wendy Munoz-Mo\u00f1tano","orcid":"https://orcid.org/0000-0003-2269-2354","observed_orcids":["https://orcid.org/0000-0003-2269-2354"]},"institutions":[{"id":"https://openalex.org/I4210119015","display_name":"Instituto Nacional de Cancerolog\u00eda","ror":"https://ror.org/02hdnbe80","country_code":"CO","type":"healthcare","lineage":["https://openalex.org/I4210119015"]},{"id":"https://openalex.org/I4210153971","display_name":"Instituto Nacional de Cancerolog\u00eda","ror":"https://ror.org/04z3afh10","country_code":"MX","type":"government","lineage":["https://openalex.org/I4210095685","https://openalex.org/I4210153971"]}],"countries":["CO","MX"],"is_corresponding":false,"raw_author_name":"Wendy Mu\u00f1oz-Monta\u00f1o","raw_affiliation_strings":["Thoracic Oncology Unit, Experimental Oncology Laboratory, Instituto Nacional de Cancerolog\u00eda (INCan), San Fernando # 22, Col. Secci\u00f3n XVI, Tlalpan, C.P. 14080, Mexico, D.F., Mexico","Instituto Nacional de Cancerolog\u00eda (INCan)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Thoracic Oncology Unit, Experimental Oncology Laboratory, Instituto Nacional de Cancerolog\u00eda (INCan), San Fernando # 22, Col. Secci\u00f3n XVI, Tlalpan, C.P. 14080, Mexico, D.F., Mexico","institution_ids":["https://openalex.org/I4210153971"]},{"raw_affiliation_string":"Instituto Nacional de Cancerolog\u00eda (INCan)","institution_ids":["https://openalex.org/I4210119015","https://openalex.org/I4210153971"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112333461","display_name":"Eleazar Omar Macedo-P\u00e9rez","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210119015","display_name":"Instituto Nacional de Cancerolog\u00eda","ror":"https://ror.org/02hdnbe80","country_code":"CO","type":"healthcare","lineage":["https://openalex.org/I4210119015"]},{"id":"https://openalex.org/I4210153971","display_name":"Instituto Nacional de Cancerolog\u00eda","ror":"https://ror.org/04z3afh10","country_code":"MX","type":"government","lineage":["https://openalex.org/I4210095685","https://openalex.org/I4210153971"]}],"countries":["CO","MX"],"is_corresponding":false,"raw_author_name":"Eleazar-Omar Macedo-P\u00e9rez","raw_affiliation_strings":["Thoracic Oncology Unit, Experimental Oncology Laboratory, Instituto Nacional de Cancerolog\u00eda (INCan), San Fernando # 22, Col. Secci\u00f3n XVI, Tlalpan, C.P. 14080, Mexico, D.F., Mexico","Instituto Nacional de Cancerolog\u00eda (INCan)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Thoracic Oncology Unit, Experimental Oncology Laboratory, Instituto Nacional de Cancerolog\u00eda (INCan), San Fernando # 22, Col. Secci\u00f3n XVI, Tlalpan, C.P. 14080, Mexico, D.F., Mexico","institution_ids":["https://openalex.org/I4210153971"]},{"raw_affiliation_string":"Instituto Nacional de Cancerolog\u00eda (INCan)","institution_ids":["https://openalex.org/I4210119015","https://openalex.org/I4210153971"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085085777","display_name":"Sa\u00e9 Mu\u00f1iz\u2010Hern\u00e1ndez","orcid":"https://orcid.org/0000-0002-6702-4010","observed_orcids":["https://orcid.org/0000-0002-6702-4010"]},"institutions":[{"id":"https://openalex.org/I4210119015","display_name":"Instituto Nacional de Cancerolog\u00eda","ror":"https://ror.org/02hdnbe80","country_code":"CO","type":"healthcare","lineage":["https://openalex.org/I4210119015"]},{"id":"https://openalex.org/I4210153971","display_name":"Instituto Nacional de Cancerolog\u00eda","ror":"https://ror.org/04z3afh10","country_code":"MX","type":"government","lineage":["https://openalex.org/I4210095685","https://openalex.org/I4210153971"]}],"countries":["CO","MX"],"is_corresponding":false,"raw_author_name":"Sa\u00e9 Mu\u00f1iz-Hern\u00e1ndez","raw_affiliation_strings":["Thoracic Oncology Unit, Experimental Oncology Laboratory, Instituto Nacional de Cancerolog\u00eda (INCan), San Fernando # 22, Col. Secci\u00f3n XVI, Tlalpan, C.P. 14080, Mexico, D.F., Mexico","Instituto Nacional de Cancerolog\u00eda (INCan)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Thoracic Oncology Unit, Experimental Oncology Laboratory, Instituto Nacional de Cancerolog\u00eda (INCan), San Fernando # 22, Col. Secci\u00f3n XVI, Tlalpan, C.P. 14080, Mexico, D.F., Mexico","institution_ids":["https://openalex.org/I4210153971"]},{"raw_affiliation_string":"Instituto Nacional de Cancerolog\u00eda (INCan)","institution_ids":["https://openalex.org/I4210119015","https://openalex.org/I4210153971"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071108397","display_name":"M\u00f3nika Blake-Cerda","orcid":"https://orcid.org/0000-0002-8696-928X","observed_orcids":["https://orcid.org/0000-0002-8696-928X"]},"institutions":[{"id":"https://openalex.org/I4210119015","display_name":"Instituto Nacional de Cancerolog\u00eda","ror":"https://ror.org/02hdnbe80","country_code":"CO","type":"healthcare","lineage":["https://openalex.org/I4210119015"]},{"id":"https://openalex.org/I4210153971","display_name":"Instituto Nacional de Cancerolog\u00eda","ror":"https://ror.org/04z3afh10","country_code":"MX","type":"government","lineage":["https://openalex.org/I4210095685","https://openalex.org/I4210153971"]}],"countries":["CO","MX"],"is_corresponding":false,"raw_author_name":"Monika Blake-Cerda","raw_affiliation_strings":["Thoracic Oncology Unit, Experimental Oncology Laboratory, Instituto Nacional de Cancerolog\u00eda (INCan), San Fernando # 22, Col. Secci\u00f3n XVI, Tlalpan, C.P. 14080, Mexico, D.F., Mexico","Instituto Nacional de Cancerolog\u00eda (INCan)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Thoracic Oncology Unit, Experimental Oncology Laboratory, Instituto Nacional de Cancerolog\u00eda (INCan), San Fernando # 22, Col. Secci\u00f3n XVI, Tlalpan, C.P. 14080, Mexico, D.F., Mexico","institution_ids":["https://openalex.org/I4210153971"]},{"raw_affiliation_string":"Instituto Nacional de Cancerolog\u00eda (INCan)","institution_ids":["https://openalex.org/I4210119015","https://openalex.org/I4210153971"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5058899614","display_name":"Jos\u00e9 Francisco Corona-Cruz","orcid":"https://orcid.org/0000-0001-5887-8834","observed_orcids":["https://orcid.org/0000-0001-5887-8834"]},"institutions":[{"id":"https://openalex.org/I4210119015","display_name":"Instituto Nacional de Cancerolog\u00eda","ror":"https://ror.org/02hdnbe80","country_code":"CO","type":"healthcare","lineage":["https://openalex.org/I4210119015"]},{"id":"https://openalex.org/I4210153971","display_name":"Instituto Nacional de Cancerolog\u00eda","ror":"https://ror.org/04z3afh10","country_code":"MX","type":"government","lineage":["https://openalex.org/I4210095685","https://openalex.org/I4210153971"]}],"countries":["CO","MX"],"is_corresponding":false,"raw_author_name":"Jos\u00e9-Francisco Corona-Cruz","raw_affiliation_strings":["Thoracic Oncology Unit, Experimental Oncology Laboratory, Instituto Nacional de Cancerolog\u00eda (INCan), San Fernando # 22, Col. Secci\u00f3n XVI, Tlalpan, C.P. 14080, Mexico, D.F., Mexico","Instituto Nacional de Cancerolog\u00eda (INCan)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Thoracic Oncology Unit, Experimental Oncology Laboratory, Instituto Nacional de Cancerolog\u00eda (INCan), San Fernando # 22, Col. Secci\u00f3n XVI, Tlalpan, C.P. 14080, Mexico, D.F., Mexico","institution_ids":["https://openalex.org/I4210153971"]},{"raw_affiliation_string":"Instituto Nacional de Cancerolog\u00eda (INCan)","institution_ids":["https://openalex.org/I4210119015","https://openalex.org/I4210153971"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5035063101"],"corresponding_institution_ids":["https://openalex.org/I4210119015","https://openalex.org/I4210153971"],"apc_list":{"value":4390,"currency":"USD","value_usd":4390},"apc_paid":null,"fwci":3.1496,"has_fulltext":false,"cited_by_count":33,"citation_normalized_percentile":{"value":0.91707281,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"73","issue":"5","first_page":"975","last_page":"982"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11026","display_name":"Occupational and environmental lung diseases","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11026","display_name":"Occupational and environmental lung diseases","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12064","display_name":"Intraperitoneal and Appendiceal Malignancies","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10202","display_name":"Lung Cancer Diagnosis and Treatment","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/malignant-pleural-mesothelioma","display_name":"malignant pleural mesothelioma","score":0.9829999804496765},{"id":"https://openalex.org/keywords/gemcitabine","display_name":"gemcitabine","score":0.8980000019073486},{"id":"https://openalex.org/keywords/cisplatin","display_name":"cisplatin","score":0.9789999723434448},{"id":"https://openalex.org/keywords/chemotherapy-toxicity","display_name":"chemotherapy toxicity","score":0.6169999837875366},{"id":"https://openalex.org/keywords/neutropenia","display_name":"neutropenia","score":0.8600000143051147},{"id":"https://openalex.org/keywords/lymphopenia","display_name":"lymphopenia","score":0.7149999737739563},{"id":"https://openalex.org/keywords/thrombocytopenia","display_name":"thrombocytopenia","score":0.9319999814033508},{"id":"https://openalex.org/keywords/anemia","display_name":"anemia","score":0.8619999885559082},{"id":"https://openalex.org/keywords/progression-free-survival","display_name":"progression-free survival","score":0.8100000023841858},{"id":"https://openalex.org/keywords/overall-survival","display_name":"overall survival","score":0.984000027179718},{"id":"https://openalex.org/keywords/quality-of-life","display_name":"quality of life","score":0.8600000143051147}],"concepts":[{"id":"https://openalex.org/C2780258809","wikidata":"https://www.wikidata.org/wiki/Q414143","display_name":"Gemcitabine","level":3,"score":0.9105837345123291},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8877452611923218},{"id":"https://openalex.org/C2777063308","wikidata":"https://www.wikidata.org/wiki/Q1435822","display_name":"Neutropenia","level":3,"score":0.5966424942016602},{"id":"https://openalex.org/C2777407522","wikidata":"https://www.wikidata.org/wiki/Q1077603","display_name":"Mesothelioma","level":2,"score":0.596504271030426},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5909350514411926},{"id":"https://openalex.org/C2778239845","wikidata":"https://www.wikidata.org/wiki/Q412415","display_name":"Cisplatin","level":3,"score":0.5576810836791992},{"id":"https://openalex.org/C2781413609","wikidata":"https://www.wikidata.org/wiki/Q7308373","display_name":"Regimen","level":2,"score":0.4969768822193146},{"id":"https://openalex.org/C2777240266","wikidata":"https://www.wikidata.org/wiki/Q415220","display_name":"Pemetrexed","level":4,"score":0.4787099361419678},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.4721940755844116},{"id":"https://openalex.org/C31760486","wikidata":"https://www.wikidata.org/wiki/Q7180990","display_name":"Phases of clinical research","level":3,"score":0.4492449164390564},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.4450991749763489},{"id":"https://openalex.org/C29730261","wikidata":"https://www.wikidata.org/wiki/Q274160","display_name":"Toxicity","level":2,"score":0.44190889596939087},{"id":"https://openalex.org/C2778397455","wikidata":"https://www.wikidata.org/wiki/Q50429865","display_name":"Antimetabolite","level":3,"score":0.41986024379730225},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.4002312123775482},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.3644048571586609},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.35656195878982544},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.14047366380691528},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000086002","descriptor_name":"Mesothelioma, Malignant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000093542","descriptor_name":"Gemcitabine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000964","descriptor_name":"Antimetabolites, Antineoplastic","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D000964","descriptor_name":"Antimetabolites, Antineoplastic","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D000964","descriptor_name":"Antimetabolites, Antineoplastic","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D002945","descriptor_name":"Cisplatin","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D002945","descriptor_name":"Cisplatin","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D002945","descriptor_name":"Cisplatin","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D003841","descriptor_name":"Deoxycytidine","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D003841","descriptor_name":"Deoxycytidine","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D003841","descriptor_name":"Deoxycytidine","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":true},{"descriptor_ui":"D003841","descriptor_name":"Deoxycytidine","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008654","descriptor_name":"Mesothelioma","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D008654","descriptor_name":"Mesothelioma","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011788","descriptor_name":"Quality of Life","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016019","descriptor_name":"Survival Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018572","descriptor_name":"Disease-Free Survival","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1007/s00280-014-2429-5","doi":"https://doi.org/10.1007/s00280-014-2429-5","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s00280-014-2429-5","pdf_url":null,"source":{"id":"https://openalex.org/S117498271","display_name":"Cancer Chemotherapy and Pharmacology","issn_l":"0344-5704","issn":["0344-5704","1432-0843"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Chemotherapy and Pharmacology","raw_type":"journal-article"},{"id":"pmid:24687408","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24687408","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer chemotherapy and pharmacology","raw_type":"Clinical Trial, Phase II"}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Clinical Trial","id":"https://openalex.org/study-designs/clinical-trial"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":45,"referenced_works":["https://openalex.org/W104179928","https://openalex.org/W1542563774","https://openalex.org/W1577877585","https://openalex.org/W1890647543","https://openalex.org/W1966598565","https://openalex.org/W1977376622","https://openalex.org/W1977874536","https://openalex.org/W1984478923","https://openalex.org/W1990104009","https://openalex.org/W1992389777","https://openalex.org/W1994277837","https://openalex.org/W1999209492","https://openalex.org/W2000556721","https://openalex.org/W2010146492","https://openalex.org/W2033599472","https://openalex.org/W2043913125","https://openalex.org/W2048035888","https://openalex.org/W2050291724","https://openalex.org/W2054602186","https://openalex.org/W2055194877","https://openalex.org/W2063525152","https://openalex.org/W2064280679","https://openalex.org/W2064862277","https://openalex.org/W2066575491","https://openalex.org/W2072620049","https://openalex.org/W2075407720","https://openalex.org/W2095824051","https://openalex.org/W2102627969","https://openalex.org/W2115425935","https://openalex.org/W2129374599","https://openalex.org/W2129967236","https://openalex.org/W2136053992","https://openalex.org/W2136813803","https://openalex.org/W2146260418","https://openalex.org/W2150001460","https://openalex.org/W2151960370","https://openalex.org/W2156148371","https://openalex.org/W2163456861","https://openalex.org/W2165221672","https://openalex.org/W2171227985","https://openalex.org/W2171446101","https://openalex.org/W2189806579","https://openalex.org/W2284799106","https://openalex.org/W2321293883","https://openalex.org/W3125565612"],"related_works":["https://openalex.org/W2054602186","https://openalex.org/W2018900164","https://openalex.org/W2050014528","https://openalex.org/W2010146492","https://openalex.org/W2163456861","https://openalex.org/W2075407720","https://openalex.org/W1999139343","https://openalex.org/W2469640064","https://openalex.org/W1999209492","https://openalex.org/W2006884367"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":2}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}