{"id":"https://openalex.org/W2108023939","doi":null,"title":"White matter lesions in panencephalopathic type of Creutzfeldt-Jakob disease: MR imaging and pathologic correlations.","display_name":"White matter lesions in panencephalopathic type of Creutzfeldt-Jakob disease: MR imaging and pathologic correlations.","publication_year":2004,"publication_date":"2004-06-01","ids":{"openalex":"https://openalex.org/W2108023939","mag":"2108023939","pmid":"https://pubmed.ncbi.nlm.nih.gov/15205123","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/7975660"},"language":"en","primary_location":{"id":"pmh:oai:pubmedcentral.nih.gov:7975660","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7975660","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"AJNR Am J Neuroradiol","raw_type":"Text"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7975660","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5036231585","display_name":"Eiji Matsusue","orcid":"https://orcid.org/0000-0002-0411-1600","observed_orcids":["https://orcid.org/0000-0002-0411-1600"]},"institutions":[{"id":"https://openalex.org/I4588055","display_name":"Tottori University","ror":"https://ror.org/024yc3q36","country_code":"JP","type":"education","lineage":["https://openalex.org/I4588055"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Eiji Matsusue","raw_affiliation_strings":["Division of Radiology, Department of Pathophysiological and Therapeutic Science, Faculty of Medicine, Tottori University, Yonago, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Radiology, Department of Pathophysiological and Therapeutic Science, Faculty of Medicine, Tottori University, Yonago, Japan","institution_ids":["https://openalex.org/I4588055"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109351508","display_name":"Toshibumi Kinoshita","orcid":"https://orcid.org/0000-0002-6210-6199","observed_orcids":["https://orcid.org/0000-0002-6210-6199"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Toshibumi Kinoshita","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110337665","display_name":"Shuji Sugihara","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Shuji Sugihara","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032979860","display_name":"Shinya Fujii","orcid":"https://orcid.org/0000-0002-6680-9932","observed_orcids":["https://orcid.org/0000-0002-6680-9932"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Shinya Fujii","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071522706","display_name":"Toshihide Ogawa","orcid":"https://orcid.org/0000-0001-8986-8452","observed_orcids":["https://orcid.org/0000-0001-8986-8452"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Toshihide Ogawa","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5056296430","display_name":"Eisaku Ohama","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Eisaku Ohama","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.0736,"has_fulltext":false,"cited_by_count":31,"citation_normalized_percentile":{"value":0.72419576,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"25","issue":"6","first_page":"910","last_page":"8"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11335","display_name":"Prion Diseases and Protein Misfolding","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11335","display_name":"Prion Diseases and Protein Misfolding","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10086","display_name":"Alzheimer's disease research and treatments","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10949","display_name":"Genetic Neurodegenerative Diseases","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/creutzfeldt-jakob-disease","display_name":"Creutzfeldt-Jakob disease","score":0.9300000071525574},{"id":"https://openalex.org/keywords/white-matter-lesions","display_name":"white matter lesions","score":0.9330000281333923},{"id":"https://openalex.org/keywords/t2-hyperintensity","display_name":"T2 hyperintensity","score":0.8970000147819519},{"id":"https://openalex.org/keywords/corticospinal-tract-degeneration","display_name":"corticospinal tract degeneration","score":0.800000011920929},{"id":"https://openalex.org/keywords/fibrillary-gliosis","display_name":"fibrillary gliosis","score":0.828000009059906},{"id":"https://openalex.org/keywords/demyelination","display_name":"demyelination","score":0.8790000081062317},{"id":"https://openalex.org/keywords/axonal-loss","display_name":"axonal loss","score":0.675000011920929},{"id":"https://openalex.org/keywords/spongy-degeneration","display_name":"spongy degeneration","score":0.6959999799728394},{"id":"https://openalex.org/keywords/histopathological-correlation","display_name":"histopathological correlation","score":0.367000013589859}],"concepts":[{"id":"https://openalex.org/C146638467","wikidata":"https://www.wikidata.org/wiki/Q10529587","display_name":"Hyperintensity","level":3,"score":0.8554983139038086},{"id":"https://openalex.org/C2781192897","wikidata":"https://www.wikidata.org/wiki/Q822050","display_name":"White matter","level":3,"score":0.8154299259185791},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.7321202158927917},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7316814064979553},{"id":"https://openalex.org/C2908656565","wikidata":"https://www.wikidata.org/wiki/Q4811564","display_name":"Astrocytosis","level":3,"score":0.6444659233093262},{"id":"https://openalex.org/C2777682930","wikidata":"https://www.wikidata.org/wiki/Q1531490","display_name":"Gliosis","level":2,"score":0.6351108551025391},{"id":"https://openalex.org/C2777796809","wikidata":"https://www.wikidata.org/wiki/Q604747","display_name":"Internal capsule","level":4,"score":0.5237277150154114},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.4482561945915222},{"id":"https://openalex.org/C2779281540","wikidata":"https://www.wikidata.org/wiki/Q5062122","display_name":"Central nervous system disease","level":2,"score":0.44050735235214233},{"id":"https://openalex.org/C2779504383","wikidata":"https://www.wikidata.org/wiki/Q41482","display_name":"Autopsy","level":2,"score":0.43036195635795593},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.13864359259605408},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.0694640576839447},{"id":"https://openalex.org/C204232928","wikidata":"https://www.wikidata.org/wiki/Q899285","display_name":"Immunohistochemistry","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001344","descriptor_name":"Autopsy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007562","descriptor_name":"Creutzfeldt-Jakob Syndrome","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"pmh:oai:pubmedcentral.nih.gov:7975660","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7975660","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"AJNR Am J Neuroradiol","raw_type":"Text"},{"id":"pmid:15205123","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15205123","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"AJNR. American journal of neuroradiology","raw_type":"Journal Article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.509.7609","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.509.7609","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://www.ajnr.org/content/25/6/910.full.pdf","raw_type":"text"},{"id":"pmh:oai:repository.lib.tottori-u.ac.jp:4257","doi":null,"is_oa":false,"landing_page_url":"http://repository.lib.tottori-u.ac.jp/4257","pdf_url":null,"source":{"id":"https://openalex.org/S4306400575","display_name":"Tottori University research result repository (Tottori University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4588055","host_organization_name":"Tottori University","host_organization_lineage":["https://openalex.org/I4588055"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":null},{"id":"mag:2108023939","doi":null,"is_oa":false,"landing_page_url":"http://www.ajnr.org/content/25/6/910.full.pdf","pdf_url":null,"source":{"id":"https://openalex.org/S101278519","display_name":"American Journal of Neuroradiology","issn_l":"0195-6108","issn":["0195-6108","1936-959X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310316165","host_organization_name":"American Society of Neuroradiology","host_organization_lineage":["https://openalex.org/P4310316165"],"host_organization_lineage_names":["American Society of Neuroradiology"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"American Journal of Neuroradiology","raw_type":null}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:7975660","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7975660","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"AJNR Am J Neuroradiol","raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9537000060081482,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/case-report","display_name":"Case Report"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":30,"referenced_works":["https://openalex.org/W36502386","https://openalex.org/W206874940","https://openalex.org/W1556206104","https://openalex.org/W1963773413","https://openalex.org/W1968139107","https://openalex.org/W1970326657","https://openalex.org/W1972293625","https://openalex.org/W1988323217","https://openalex.org/W1990148513","https://openalex.org/W1996461056","https://openalex.org/W1999992836","https://openalex.org/W2021204133","https://openalex.org/W2024737263","https://openalex.org/W2031088948","https://openalex.org/W2036396605","https://openalex.org/W2036846324","https://openalex.org/W2051391548","https://openalex.org/W2077932434","https://openalex.org/W2087634212","https://openalex.org/W2096736542","https://openalex.org/W2129725719","https://openalex.org/W2148999800","https://openalex.org/W2149472811","https://openalex.org/W2167983339","https://openalex.org/W2184529280","https://openalex.org/W2186362659","https://openalex.org/W2407098675","https://openalex.org/W2407633305","https://openalex.org/W2410206674","https://openalex.org/W2416569375"],"related_works":["https://openalex.org/W2077932434","https://openalex.org/W1988323217","https://openalex.org/W2407633305","https://openalex.org/W1985686048","https://openalex.org/W2009595384","https://openalex.org/W1556206104","https://openalex.org/W2008045578","https://openalex.org/W1996461056","https://openalex.org/W2417233558","https://openalex.org/W1510199282"],"abstract_inverted_index":{"BACKGROUND":[0],"AND":[1],"PURPOSE:":[2],"A":[3],"panencephalopathic":[4],"type":[5],"of":[6,16,33,48,76,82,86,95,157,176,184,211,236,242],"Creutzfeldt-Jakob":[7],"disease":[8],"(pCJD)":[9],"is":[10],"characterized":[11],"by":[12,54,98,216],"the":[13,17,24,37,62,106,116,121,139,146,158,177,181,197,201,237,240,243],"extensive":[14],"involvement":[15,175],"cerebral":[18,25,107,117,148,251],"white":[19,38,63,118,136,149,159,178,225,254],"matter":[20,39,64,109,119,137,150,160,226,255],"as":[21,23],"well":[22],"gray":[26,108],"matter.":[27,179],"It":[28],"has":[29],"been":[30],"a":[31,187],"point":[32],"controversy,":[34],"however,":[35],"whether":[36,61],"changes":[40,75,164,235],"represent":[41],"primary":[42,69,174,234],"or":[43,70,165,250,252],"secondary":[44,71,221,247],"degeneration.":[45,72,222],"The":[46],"aim":[47],"this":[49],"study":[50],"was":[51],"to":[52,132,145,232,248],"elucidate,":[53],"using":[55],"MR":[56,93,191],"images":[57,94,192],"and":[58,79,114,134,143,204,213],"histologic":[59,80],"examinations,":[60],"lesions":[65,161,227,241],"in":[66,105,115,196,200,228],"pCJD":[67,87,99,229],"are":[68],"METHODS:":[73],"Serial":[74,92],"T2":[77,102,194],"hyperintensities":[78,103,195],"findings":[81],"six":[83],"autopsy-proved":[84],"cases":[85,185],"were":[88,230,246],"retrospectively":[89],"analyzed.":[90],"RESULTS:":[91],"brains":[96],"affected":[97],"revealed":[100,162],"that":[101,219],"appeared":[104],"2-5":[110],"months":[111,126,142,152],"after":[112,127,153],"onset":[113],"around":[120],"lateral":[122],"ventricles":[123],"approximately":[124],"5":[125],"onset.":[128,154],"They":[129],"rapidly":[130],"extended":[131],"deep":[133],"subcortical":[135],"during":[138],"next":[140],"several":[141],"then":[144],"entire":[147],"10":[151],"Histologic":[155],"examination":[156],"spongy":[163],"tissue":[166],"rarefaction":[167],"associated":[168],"with":[169,186],"gemistocytic":[170],"astrocytosis,":[171],"which":[172,207],"indicates":[173,220],"At":[180],"terminal":[182],"stages":[183],"longer":[188],"clinical":[189],"course,":[190],"showed":[193],"corticospinal":[198,244],"tracts":[199,245],"internal":[202],"capsule":[203],"brain":[205],"stem,":[206],"histologically":[208],"disclosed":[209],"loss":[210],"myelin":[212],"axons":[214],"accompanied":[215],"fibrillary":[217],"gliosis":[218],"CONCLUSION:":[223],"Cerebral":[224],"considered":[231],"be":[233],"disease,":[238],"but":[239],"cortical":[249],"both":[253],"lesions.":[256]},"counts_by_year":[{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}