{"id":"https://openalex.org/W2107926040","doi":"https://doi.org/10.1142/s0192415x05002928","title":"Atropine-Induced HRV Alteration is Not Amended by Electroacupuncture on Zusanli","display_name":"Atropine-Induced HRV Alteration is Not Amended by Electroacupuncture on Zusanli","publication_year":2005,"publication_date":"2005-01-01","ids":{"openalex":"https://openalex.org/W2107926040","doi":"https://doi.org/10.1142/s0192415x05002928","mag":"2107926040","pmid":"https://pubmed.ncbi.nlm.nih.gov/15974489"},"language":"en","primary_location":{"id":"doi:10.1142/s0192415x05002928","doi":"https://doi.org/10.1142/s0192415x05002928","is_oa":false,"landing_page_url":"https://doi.org/10.1142/s0192415x05002928","pdf_url":null,"source":{"id":"https://openalex.org/S118315377","display_name":"The American Journal of Chinese Medicine","issn_l":"0090-2942","issn":["0090-2942","0192-415X","1793-6853"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319815","host_organization_name":"World Scientific","host_organization_lineage":["https://openalex.org/P4310319815"],"host_organization_lineage_names":["World Scientific"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American Journal of Chinese Medicine","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5113662647","display_name":"Chi-Hsien Chang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I162838928","display_name":"National Chung Hsing University","ror":"https://ror.org/05vn3ca78","country_code":"TW","type":"education","lineage":["https://openalex.org/I162838928"]},{"id":"https://openalex.org/I4210091773","display_name":"Taichung Veterans General Hospital","ror":"https://ror.org/00e87hq62","country_code":"TW","type":"healthcare","lineage":["https://openalex.org/I4210091773"]},{"id":"https://openalex.org/I91279580","display_name":"Chung Shan Medical University","ror":"https://ror.org/059ryjv25","country_code":"TW","type":"education","lineage":["https://openalex.org/I91279580"]},{"id":"https://openalex.org/I99613584","display_name":"National Taipei University","ror":"https://ror.org/03e29r284","country_code":"TW","type":"education","lineage":["https://openalex.org/I99613584"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Chi-Hsien Chang","raw_affiliation_strings":["Division of Gastroenterology, Taichung Veterans General Hospital, ROC","Institute of Food Science, National Chung Hsing University, ROC","Institute of Internal Medicine, Chung Shan Medical University, Taichung, Taiwan, ROC","Institute of Food Science, National Chung Hsing University, Taipei, Taiwan. changcs@vghtc.gov.tw"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Gastroenterology, Taichung Veterans General Hospital, ROC","institution_ids":["https://openalex.org/I4210091773"]},{"raw_affiliation_string":"Institute of Food Science, National Chung Hsing University, ROC","institution_ids":["https://openalex.org/I162838928"]},{"raw_affiliation_string":"Institute of Internal Medicine, Chung Shan Medical University, Taichung, Taiwan, ROC","institution_ids":["https://openalex.org/I91279580"]},{"raw_affiliation_string":"Institute of Food Science, National Chung Hsing University, Taipei, Taiwan. changcs@vghtc.gov.tw","institution_ids":["https://openalex.org/I162838928","https://openalex.org/I99613584"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090509650","display_name":"Jin\u2010Long Huang","orcid":"https://orcid.org/0000-0001-6566-5546","observed_orcids":["https://orcid.org/0000-0001-6566-5546"]},"institutions":[{"id":"https://openalex.org/I4210091773","display_name":"Taichung Veterans General Hospital","ror":"https://ror.org/00e87hq62","country_code":"TW","type":"healthcare","lineage":["https://openalex.org/I4210091773"]},{"id":"https://openalex.org/I4387156312","display_name":"National Yang Ming University","ror":"https://ror.org/009h5ks85","country_code":"TW","type":"education","lineage":["https://openalex.org/I148366613","https://openalex.org/I4387156312"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Jin-Long Huang","raw_affiliation_strings":["Division of Cardiology, Taichung Veterans General Hospital, ROC","Institute of Clinical Medicine, National Yang-Min University, Taipei, Taiwan, ROC"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology, Taichung Veterans General Hospital, ROC","institution_ids":["https://openalex.org/I4210091773"]},{"raw_affiliation_string":"Institute of Clinical Medicine, National Yang-Min University, Taipei, Taiwan, ROC","institution_ids":["https://openalex.org/I4387156312"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064286188","display_name":"Chih-Tai Ting","orcid":"https://orcid.org/0000-0003-4909-3001","observed_orcids":["https://orcid.org/0000-0003-4909-3001"]},"institutions":[{"id":"https://openalex.org/I4210091773","display_name":"Taichung Veterans General Hospital","ror":"https://ror.org/00e87hq62","country_code":"TW","type":"healthcare","lineage":["https://openalex.org/I4210091773"]},{"id":"https://openalex.org/I4387156312","display_name":"National Yang Ming University","ror":"https://ror.org/009h5ks85","country_code":"TW","type":"education","lineage":["https://openalex.org/I148366613","https://openalex.org/I4387156312"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Chih-Tai Ting","raw_affiliation_strings":["Division of Cardiology, Taichung Veterans General Hospital, ROC","Institute of Clinical Medicine, National Yang-Min University, Taipei, Taiwan, ROC"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology, Taichung Veterans General Hospital, ROC","institution_ids":["https://openalex.org/I4210091773"]},{"raw_affiliation_string":"Institute of Clinical Medicine, National Yang-Min University, Taipei, Taiwan, ROC","institution_ids":["https://openalex.org/I4387156312"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045659664","display_name":"Chi\u2010Sen Chang","orcid":"https://orcid.org/0000-0002-1192-030X","observed_orcids":["https://orcid.org/0000-0002-1192-030X"]},"institutions":[{"id":"https://openalex.org/I162838928","display_name":"National Chung Hsing University","ror":"https://ror.org/05vn3ca78","country_code":"TW","type":"education","lineage":["https://openalex.org/I162838928"]},{"id":"https://openalex.org/I4210091773","display_name":"Taichung Veterans General Hospital","ror":"https://ror.org/00e87hq62","country_code":"TW","type":"healthcare","lineage":["https://openalex.org/I4210091773"]},{"id":"https://openalex.org/I91279580","display_name":"Chung Shan Medical University","ror":"https://ror.org/059ryjv25","country_code":"TW","type":"education","lineage":["https://openalex.org/I91279580"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Chi-Sen Chang","raw_affiliation_strings":["Division of Gastroenterology, Taichung Veterans General Hospital, ROC","Institute of Food Science, National Chung Hsing University, ROC","Institute of Internal Medicine, Chung Shan Medical University, Taichung, Taiwan, ROC"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Gastroenterology, Taichung Veterans General Hospital, ROC","institution_ids":["https://openalex.org/I4210091773"]},{"raw_affiliation_string":"Institute of Food Science, National Chung Hsing University, ROC","institution_ids":["https://openalex.org/I162838928"]},{"raw_affiliation_string":"Institute of Internal Medicine, Chung Shan Medical University, Taichung, Taiwan, ROC","institution_ids":["https://openalex.org/I91279580"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5016663943","display_name":"Gran\u2010Hum Chen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210091773","display_name":"Taichung Veterans General Hospital","ror":"https://ror.org/00e87hq62","country_code":"TW","type":"healthcare","lineage":["https://openalex.org/I4210091773"]},{"id":"https://openalex.org/I4387156312","display_name":"National Yang Ming University","ror":"https://ror.org/009h5ks85","country_code":"TW","type":"education","lineage":["https://openalex.org/I148366613","https://openalex.org/I4387156312"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Gran-Hum Chen","raw_affiliation_strings":["Division of Gastroenterology, Taichung Veterans General Hospital, ROC","Institute of Clinical Medicine, National Yang-Min University, Taipei, Taiwan, ROC"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Gastroenterology, Taichung Veterans General Hospital, ROC","institution_ids":["https://openalex.org/I4210091773"]},{"raw_affiliation_string":"Institute of Clinical Medicine, National Yang-Min University, Taipei, Taiwan, ROC","institution_ids":["https://openalex.org/I4387156312"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":8.8602,"has_fulltext":false,"cited_by_count":37,"citation_normalized_percentile":{"value":0.96783254,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"33","issue":"02","first_page":"307","last_page":"314"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11327","display_name":"Acupuncture Treatment Research Studies","score":0.9951000213623047,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11327","display_name":"Acupuncture Treatment Research Studies","score":0.9951000213623047,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10745","display_name":"Heart Rate Variability and Autonomic Control","score":0.0019000000320374966,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12580","display_name":"Vagus Nerve Stimulation Research","score":0.0012000000569969416,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/electroacupuncture","display_name":"electroacupuncture","score":0.984000027179718},{"id":"https://openalex.org/keywords/zusanli-st36","display_name":"Zusanli (ST36)","score":0.9100000262260437},{"id":"https://openalex.org/keywords/atropine","display_name":"atropine","score":0.9449999928474426},{"id":"https://openalex.org/keywords/heart-rate-variability","display_name":"heart rate variability","score":0.9990000128746033},{"id":"https://openalex.org/keywords/vagal-pathway","display_name":"vagal pathway","score":0.8080000281333923},{"id":"https://openalex.org/keywords/autonomic-nervous-system","display_name":"autonomic nervous system","score":0.8510000109672546},{"id":"https://openalex.org/keywords/sympathetic-nerve-activity","display_name":"sympathetic activity","score":0.7540000081062317},{"id":"https://openalex.org/keywords/lf-hf-ratio","display_name":"LF/HF ratio","score":0.8840000033378601},{"id":"https://openalex.org/keywords/gastric-myoelectrical-activity","display_name":"gastric myoelectrical activity","score":0.7570000290870667},{"id":"https://openalex.org/keywords/gastric-emptying","display_name":"gastric emptying","score":0.7630000114440918},{"id":"https://openalex.org/keywords/gastrin","display_name":"gastrin","score":0.8889999985694885},{"id":"https://openalex.org/keywords/motilin","display_name":"motilin","score":0.9980000257492065},{"id":"https://openalex.org/keywords/pancreatic-polypeptide","display_name":"pancreatic polypeptide","score":0.9990000128746033}],"concepts":[{"id":"https://openalex.org/C2779504368","wikidata":"https://www.wikidata.org/wiki/Q10972389","display_name":"Zusanli","level":5,"score":0.990653395652771},{"id":"https://openalex.org/C2776202274","wikidata":"https://www.wikidata.org/wiki/Q11784952","display_name":"Electroacupuncture","level":4,"score":0.957764208316803},{"id":"https://openalex.org/C2775859210","wikidata":"https://www.wikidata.org/wiki/Q26272","display_name":"Atropine","level":2,"score":0.7820335626602173},{"id":"https://openalex.org/C56837625","wikidata":"https://www.wikidata.org/wiki/Q121713","display_name":"Acupuncture","level":3,"score":0.7189828157424927},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6770780086517334},{"id":"https://openalex.org/C131793682","wikidata":"https://www.wikidata.org/wiki/Q126440","display_name":"Motilin","level":2,"score":0.6102014780044556},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.6097174882888794},{"id":"https://openalex.org/C71635504","wikidata":"https://www.wikidata.org/wiki/Q933954","display_name":"Heart rate variability","level":4,"score":0.5587681531906128},{"id":"https://openalex.org/C2778300832","wikidata":"https://www.wikidata.org/wiki/Q1589604","display_name":"Premedication","level":2,"score":0.4415462613105774},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3888888359069824},{"id":"https://openalex.org/C2777953023","wikidata":"https://www.wikidata.org/wiki/Q1073121","display_name":"Heart rate","level":3,"score":0.22255784273147583},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.07456034421920776},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000889","descriptor_name":"Anti-Arrhythmia Agents","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D000889","descriptor_name":"Anti-Arrhythmia Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D001285","descriptor_name":"Atropine","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D001285","descriptor_name":"Atropine","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D001341","descriptor_name":"Autonomic Nervous System","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D006339","descriptor_name":"Heart Rate","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007262","descriptor_name":"Infusions, Intravenous","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010919","descriptor_name":"Placebos","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015671","descriptor_name":"Electroacupuncture","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1142/s0192415x05002928","doi":"https://doi.org/10.1142/s0192415x05002928","is_oa":false,"landing_page_url":"https://doi.org/10.1142/s0192415x05002928","pdf_url":null,"source":{"id":"https://openalex.org/S118315377","display_name":"The American Journal of Chinese Medicine","issn_l":"0090-2942","issn":["0090-2942","0192-415X","1793-6853"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319815","host_organization_name":"World Scientific","host_organization_lineage":["https://openalex.org/P4310319815"],"host_organization_lineage_names":["World Scientific"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American Journal of Chinese Medicine","raw_type":"journal-article"},{"id":"pmid:15974489","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15974489","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American journal of Chinese medicine","raw_type":"Clinical Trial"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9907000064849854,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320326232","display_name":"Taichung Veterans General Hospital","ror":"https://ror.org/00e87hq62"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":19,"referenced_works":["https://openalex.org/W67248436","https://openalex.org/W199464057","https://openalex.org/W1483080261","https://openalex.org/W1863864373","https://openalex.org/W2008545940","https://openalex.org/W2025784853","https://openalex.org/W2027153376","https://openalex.org/W2029187825","https://openalex.org/W2040183537","https://openalex.org/W2049455604","https://openalex.org/W2087220596","https://openalex.org/W2088575453","https://openalex.org/W2125710946","https://openalex.org/W2133589238","https://openalex.org/W2147293330","https://openalex.org/W2167262287","https://openalex.org/W2178951657","https://openalex.org/W2285072859","https://openalex.org/W2416989585"],"related_works":["https://openalex.org/W2127808585","https://openalex.org/W199464057","https://openalex.org/W2062627365","https://openalex.org/W2416809673","https://openalex.org/W2124198680","https://openalex.org/W2358206712","https://openalex.org/W1969415393","https://openalex.org/W2749215556","https://openalex.org/W2365045774","https://openalex.org/W2794857281"],"abstract_inverted_index":{"Acupuncture":[0,8],"is":[1,238],"known":[2],"to":[3,15,40],"influence":[4],"autonomic":[5,44],"nervous":[6,45],"activity.":[7],"on":[9,58,88,103,158,243],"Zusanli":[10,59,90,160,244],"points":[11,93],"has":[12],"been":[13],"shown":[14],"enhance":[16],"the":[17,29,89,141,149,159,169,176,183,196,200,214,231],"regularity":[18],"of":[19,36,98,108,125,155],"gastric":[20,25],"myoelectrical":[21],"activity":[22],"and":[23,71,100,115,128,179,185,202],"accelerate":[24],"emptying,":[26],"partly":[27],"through":[28],"vagal":[30,232],"pathway,":[31],"in":[32,65,81,140,175,195,210,213],"dogs.":[33],"The":[34,106],"aim":[35],"this":[37],"study":[38],"was":[39,76,137,165,172,191,206],"evaluate":[41],"whether":[42],"atropine-induced":[43,224,235],"alteration,":[46],"measured":[47],"by":[48,56,241],"heart":[49],"rate":[50],"variability":[51],"(HRV),":[52],"could":[53],"be":[54,228],"amended":[55,240],"electroacupuncture":[57,87,242],"points.":[60,245],"HRV":[61,225,236],"measurements":[62],"were":[63,118,133],"recorded":[64],"15":[66],"healthy":[67],"volunteers":[68],"before,":[69],"during":[70,148,182,199],"after":[72,217],"electroacupuncture.":[73],"Each":[74],"subject":[75],"studied":[77],"for":[78],"three":[79],"sessions":[80],"a":[82,104,173,192,207],"randomized":[83],"sequence,":[84],"which":[85],"included":[86],"(St":[91],"36)":[92],"with":[94,152,219],"or":[95],"without":[96],"premedication":[97,218],"atropine":[99,164],"placebo":[101],"stimulation":[102,157],"non-acupoint.":[105],"analysis":[107],"low":[109],"frequency":[110,113],"(LF),":[111],"high":[112],"(HF)":[114],"LF/HF":[116,142,197],"ratios":[117],"compared":[119],"between":[120],"different":[121],"sessions.":[122],"Serum":[123],"levels":[124,132],"gastrin,":[126],"motilin":[127],"pancreatic":[129],"polypeptide":[130],"(PP)":[131],"also":[134],"measured.":[135],"There":[136,205],"an":[138],"increase":[139,194],"ratio":[143,198],"(indicating":[144],"increased":[145],"sympathetic":[146],"activity)":[147],"post-acupuncture":[150,186,203,215],"period":[151,216],"2":[153],"Hz":[154],"electrical":[156],"acupoints.":[161],"When":[162],"IV":[163,220],"used":[166],"immediately":[167],"before":[168],"electroacupuncture,":[170],"there":[171,190],"decrease":[174,209],"LF":[177],"power":[178,181],"HF":[180],"acupuncture":[184,201],"periods.":[187,204],"In":[188,222],"addition,":[189],"significant":[193,208],"serum":[211],"PP":[212],"atropine.":[221],"conclusion,":[223],"change":[226],"might":[227],"mediated":[229],"via":[230],"pathway.":[233],"However,":[234],"alteration":[237],"not":[239]},"counts_by_year":[{"year":2021,"cited_by_count":3},{"year":2019,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":6}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}