{"id":"https://openalex.org/W2107924152","doi":"https://doi.org/10.2217/nnm.14.36","title":"3D Nano/Microfabrication Techniques and Nanobiomaterials for Neural Tissue Regeneration","display_name":"3D Nano/Microfabrication Techniques and Nanobiomaterials for Neural Tissue Regeneration","publication_year":2014,"publication_date":"2014-05-01","ids":{"openalex":"https://openalex.org/W2107924152","doi":"https://doi.org/10.2217/nnm.14.36","mag":"2107924152","pmid":"https://pubmed.ncbi.nlm.nih.gov/24981651"},"language":"en","primary_location":{"id":"doi:10.2217/nnm.14.36","doi":"https://doi.org/10.2217/nnm.14.36","is_oa":false,"landing_page_url":"https://doi.org/10.2217/nnm.14.36","pdf_url":null,"source":{"id":"https://openalex.org/S4210216406","display_name":"Nanomedicine","issn_l":"1743-5889","issn":["1743-5889","1748-6963"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310321119","host_organization_name":"Future Medicine","host_organization_lineage":["https://openalex.org/P4310321119"],"host_organization_lineage_names":["Future Medicine"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nanomedicine","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101415381","display_name":"Wei Zhu","orcid":"https://orcid.org/0000-0003-1809-3578","observed_orcids":["https://orcid.org/0000-0003-1809-3578"]},"institutions":[{"id":"https://openalex.org/I193531525","display_name":"George Washington University","ror":"https://ror.org/00y4zzh67","country_code":"US","type":"education","lineage":["https://openalex.org/I193531525"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Wei Zhu","raw_affiliation_strings":["Department of Mechanical & Aerospace Engineering, The George Washington University, Washington, DC20052, USA","[Department of Mechanical and Aerospace Engineering, The George Washington University, Washington, DC 20052, USA]"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Mechanical & Aerospace Engineering, The George Washington University, Washington, DC20052, USA","institution_ids":["https://openalex.org/I193531525"]},{"raw_affiliation_string":"[Department of Mechanical and Aerospace Engineering, The George Washington University, Washington, DC 20052, USA]","institution_ids":["https://openalex.org/I193531525"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109006503","display_name":"Christopher O\u2019Brien","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I193531525","display_name":"George Washington University","ror":"https://ror.org/00y4zzh67","country_code":"US","type":"education","lineage":["https://openalex.org/I193531525"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Christopher O'Brien","raw_affiliation_strings":["Department of Mechanical & Aerospace Engineering, The George Washington University, Washington, DC20052, USA","[Department of Mechanical and Aerospace Engineering, The George Washington University, Washington, DC 20052, USA]"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Mechanical & Aerospace Engineering, The George Washington University, Washington, DC20052, USA","institution_ids":["https://openalex.org/I193531525"]},{"raw_affiliation_string":"[Department of Mechanical and Aerospace Engineering, The George Washington University, Washington, DC 20052, USA]","institution_ids":["https://openalex.org/I193531525"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101987144","display_name":"Joseph R O'Brien","orcid":"https://orcid.org/0000-0001-9559-0338","observed_orcids":["https://orcid.org/0000-0001-9559-0338"]},"institutions":[{"id":"https://openalex.org/I193531525","display_name":"George Washington University","ror":"https://ror.org/00y4zzh67","country_code":"US","type":"education","lineage":["https://openalex.org/I193531525"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Joseph R O'Brien","raw_affiliation_strings":["Departments of Orthopedic Surgery & Neurological Surgery, The George Washington University, Washington, DC20052, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Orthopedic Surgery & Neurological Surgery, The George Washington University, Washington, DC20052, USA","institution_ids":["https://openalex.org/I193531525"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5082297222","display_name":"Lijie Grace Zhang","orcid":"https://orcid.org/0000-0003-3009-045X","observed_orcids":["https://orcid.org/0000-0003-3009-045X"]},"institutions":[{"id":"https://openalex.org/I193531525","display_name":"George Washington University","ror":"https://ror.org/00y4zzh67","country_code":"US","type":"education","lineage":["https://openalex.org/I193531525"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lijie Grace Zhang","raw_affiliation_strings":["Department of Mechanical & Aerospace Engineering, The George Washington University, Washington, DC20052, USA","Department of Medicine, The George Washington University, Washington, DC20052, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Mechanical & Aerospace Engineering, The George Washington University, Washington, DC20052, USA","institution_ids":["https://openalex.org/I193531525"]},{"raw_affiliation_string":"Department of Medicine, The George Washington University, Washington, DC20052, USA","institution_ids":["https://openalex.org/I193531525"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I193531525"],"apc_list":null,"apc_paid":null,"fwci":0.9585,"has_fulltext":false,"cited_by_count":122,"citation_normalized_percentile":{"value":0.68615984,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":100},"biblio":{"volume":"9","issue":"6","first_page":"859","last_page":"875"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10729","display_name":"Electrospun Nanofibers in Biomedical Applications","score":0.7651000022888184,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10729","display_name":"Electrospun Nanofibers in Biomedical Applications","score":0.7651000022888184,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10483","display_name":"Nerve injury and regeneration","score":0.18950000405311584,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11601","display_name":"Neuroscience and Neural Engineering","score":0.017100000753998756,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/neural-tissue-regeneration","display_name":"neural tissue regeneration","score":0.9559999704360962},{"id":"https://openalex.org/keywords/nerve-injury","display_name":"nerve injury","score":0.6679999828338623},{"id":"https://openalex.org/keywords/nerve-guidance-conduits","display_name":"nerve conduits","score":0.8659999966621399},{"id":"https://openalex.org/keywords/nerve-scaffolds","display_name":"neural scaffolds","score":0.8579999804496765},{"id":"https://openalex.org/keywords/nanobiomaterials","display_name":"nanobiomaterials","score":0.9020000100135803},{"id":"https://openalex.org/keywords/electrospinning","display_name":"electrospinning","score":0.8180000185966492},{"id":"https://openalex.org/keywords/3d-printing","display_name":"3D printing","score":0.8999999761581421},{"id":"https://openalex.org/keywords/self-assembly","display_name":"self-assembly","score":0.9929999709129333},{"id":"https://openalex.org/keywords/biomimetic-scaffolds","display_name":"biomimetic scaffolds","score":0.8109999895095825},{"id":"https://openalex.org/keywords/tissue-engineering","display_name":"tissue engineering","score":0.5989999771118164}],"concepts":[{"id":"https://openalex.org/C187761678","wikidata":"https://www.wikidata.org/wiki/Q7002068","display_name":"Neural tissue engineering","level":3,"score":0.8653138279914856},{"id":"https://openalex.org/C171056886","wikidata":"https://www.wikidata.org/wiki/Q193119","display_name":"Regeneration (biology)","level":2,"score":0.6994276642799377},{"id":"https://openalex.org/C49892992","wikidata":"https://www.wikidata.org/wiki/Q1540285","display_name":"Tissue engineering","level":2,"score":0.6959512233734131},{"id":"https://openalex.org/C2779343474","wikidata":"https://www.wikidata.org/wiki/Q3109175","display_name":"Context (archaeology)","level":2,"score":0.6363855600357056},{"id":"https://openalex.org/C527607","wikidata":"https://www.wikidata.org/wiki/Q175538","display_name":"Microfabrication","level":4,"score":0.6269397735595703},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.5317054390907288},{"id":"https://openalex.org/C144796933","wikidata":"https://www.wikidata.org/wiki/Q1533542","display_name":"Electrospinning","level":3,"score":0.4762026071548462},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.45313966274261475},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.442754864692688},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.34435558319091797},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.19439810514450073},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.13394248485565186},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.11014875769615173},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.07122007012367249},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0},{"id":"https://openalex.org/C159985019","wikidata":"https://www.wikidata.org/wiki/Q181790","display_name":"Composite material","level":1,"score":0.0},{"id":"https://openalex.org/C136525101","wikidata":"https://www.wikidata.org/wiki/Q5428139","display_name":"Fabrication","level":3,"score":0.0},{"id":"https://openalex.org/C521977710","wikidata":"https://www.wikidata.org/wiki/Q81163","display_name":"Polymer","level":2,"score":0.0},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001672","descriptor_name":"Biocompatible Materials","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D001672","descriptor_name":"Biocompatible Materials","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D004867","descriptor_name":"Equipment Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009416","descriptor_name":"Nerve Regeneration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D023822","descriptor_name":"Tissue Engineering","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D036103","descriptor_name":"Nanotechnology","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D036103","descriptor_name":"Nanotechnology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D048091","descriptor_name":"Guided Tissue Regeneration","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D049329","descriptor_name":"Nanostructures","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D049329","descriptor_name":"Nanostructures","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D049329","descriptor_name":"Nanostructures","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D054457","descriptor_name":"Tissue Scaffolds","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D055616","descriptor_name":"Microtechnology","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D055616","descriptor_name":"Microtechnology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.2217/nnm.14.36","doi":"https://doi.org/10.2217/nnm.14.36","is_oa":false,"landing_page_url":"https://doi.org/10.2217/nnm.14.36","pdf_url":null,"source":{"id":"https://openalex.org/S4210216406","display_name":"Nanomedicine","issn_l":"1743-5889","issn":["1743-5889","1748-6963"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310321119","host_organization_name":"Future Medicine","host_organization_lineage":["https://openalex.org/P4310321119"],"host_organization_lineage_names":["Future Medicine"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nanomedicine","raw_type":"journal-article"},{"id":"pmid:24981651","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24981651","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nanomedicine (London, England)","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.46810001134872437,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":115,"referenced_works":["https://openalex.org/W28689500","https://openalex.org/W1517550653","https://openalex.org/W1964387551","https://openalex.org/W1966848625","https://openalex.org/W1969158381","https://openalex.org/W1970435814","https://openalex.org/W1974587859","https://openalex.org/W1976632391","https://openalex.org/W1977232263","https://openalex.org/W1979079389","https://openalex.org/W1979169277","https://openalex.org/W1981481147","https://openalex.org/W1981722629","https://openalex.org/W1982397697","https://openalex.org/W1984417662","https://openalex.org/W1985316276","https://openalex.org/W1988343344","https://openalex.org/W1989093439","https://openalex.org/W1990764536","https://openalex.org/W1990836922","https://openalex.org/W1991914157","https://openalex.org/W1993817314","https://openalex.org/W1997028439","https://openalex.org/W1997193051","https://openalex.org/W1997552417","https://openalex.org/W2001784553","https://openalex.org/W2009514460","https://openalex.org/W2010294852","https://openalex.org/W2011318299","https://openalex.org/W2011546412","https://openalex.org/W2012768695","https://openalex.org/W2014891480","https://openalex.org/W2017208938","https://openalex.org/W2017545194","https://openalex.org/W2018858346","https://openalex.org/W2019043097","https://openalex.org/W2021643587","https://openalex.org/W2022577997","https://openalex.org/W2023599099","https://openalex.org/W2023913887","https://openalex.org/W2025606893","https://openalex.org/W2026688829","https://openalex.org/W2028631399","https://openalex.org/W2028814484","https://openalex.org/W2029039324","https://openalex.org/W2029124160","https://openalex.org/W2030221933","https://openalex.org/W2030495029","https://openalex.org/W2030496781","https://openalex.org/W2030744048","https://openalex.org/W2033406893","https://openalex.org/W2033699260","https://openalex.org/W2039497282","https://openalex.org/W2040048481","https://openalex.org/W2040855747","https://openalex.org/W2045744140","https://openalex.org/W2048903275","https://openalex.org/W2058841553","https://openalex.org/W2058854067","https://openalex.org/W2060250281","https://openalex.org/W2060300022","https://openalex.org/W2061073729","https://openalex.org/W2063056421","https://openalex.org/W2063992448","https://openalex.org/W2064496774","https://openalex.org/W2065613288","https://openalex.org/W2066303539","https://openalex.org/W2066648103","https://openalex.org/W2067065320","https://openalex.org/W2067994009","https://openalex.org/W2069183513","https://openalex.org/W2072193382","https://openalex.org/W2073795835","https://openalex.org/W2075477218","https://openalex.org/W2080468808","https://openalex.org/W2080558953","https://openalex.org/W2081924426","https://openalex.org/W2083457177","https://openalex.org/W2085424855","https://openalex.org/W2085530837","https://openalex.org/W2087131768","https://openalex.org/W2090991686","https://openalex.org/W2093483666","https://openalex.org/W2096214578","https://openalex.org/W2099995006","https://openalex.org/W2100663189","https://openalex.org/W2107514110","https://openalex.org/W2109613040","https://openalex.org/W2111411042","https://openalex.org/W2112026052","https://openalex.org/W2113230122","https://openalex.org/W2116800744","https://openalex.org/W2118545851","https://openalex.org/W2121238039","https://openalex.org/W2126974532","https://openalex.org/W2130119039","https://openalex.org/W2130985015","https://openalex.org/W2134418903","https://openalex.org/W2135799879","https://openalex.org/W2136511265","https://openalex.org/W2142720627","https://openalex.org/W2142998520","https://openalex.org/W2146276847","https://openalex.org/W2157908104","https://openalex.org/W2158748999","https://openalex.org/W2164939852","https://openalex.org/W2165685541","https://openalex.org/W2166204670","https://openalex.org/W2167445451","https://openalex.org/W2168528461","https://openalex.org/W2168893672","https://openalex.org/W2169327044","https://openalex.org/W2592718512","https://openalex.org/W4211147424","https://openalex.org/W4250113749"],"related_works":["https://openalex.org/W2481996014","https://openalex.org/W4214878994","https://openalex.org/W4230620701","https://openalex.org/W2525968609","https://openalex.org/W2087131768","https://openalex.org/W2898483217","https://openalex.org/W4408740957","https://openalex.org/W2604370702","https://openalex.org/W4416542726","https://openalex.org/W2804715340"],"abstract_inverted_index":{"Injuries":[0],"of":[1,9,34,59,82,114],"the":[2,39,80],"nervous":[3],"system":[4],"occur":[5],"commonly":[6],"among":[7],"people":[8],"many":[10,35],"different":[11],"ages":[12],"and":[13,57,84,93,137,141],"backgrounds.":[14],"Currently,":[15],"there":[16],"are":[17],"no":[18],"effective":[19],"strategies":[20],"to":[21,69,101,110],"improve":[22],"neural":[23,40,74,106,130,146],"regeneration;":[24],"however,":[25],"tissue":[26,36,47,95,147],"engineering":[27,48,96],"provides":[28,76],"a":[29,66,111],"promising":[30],"avenue":[31],"for":[32,55,79,104,144],"regeneration":[33],"types,":[37],"including":[38],"context.":[41],"Functional":[42],"nerve":[43,86],"conduits":[44,89],"derived":[45,90],"from":[46,91],"techniques":[49,97],"present":[50],"bioengineered":[51],"3D":[52,128,135],"artificial":[53],"substitutes":[54],"implantation":[56],"rehabilitation":[58],"injured":[60],"nerves.":[61],"In":[62,117],"particular,":[63],"nanotechnology":[64],"as":[65],"versatile":[67],"vehicle":[68],"create":[70],"biomimetic":[71,115],"nanostructured":[72],"tissue-engineered":[73],"scaffolds":[75,131],"great":[77],"potential":[78],"development":[81],"innovative":[83],"successful":[85,105],"grafts.":[87],"Nanostructured":[88],"traditional":[92],"novel":[94],"have":[98],"been":[99],"shown":[100],"be":[102],"superior":[103],"function":[107],"construction":[108],"due":[109],"high":[112],"degree":[113],"character.":[116],"this":[118],"paper,":[119],"we":[120],"will":[121],"focus":[122],"on":[123],"current":[124],"progress":[125],"in":[126],"developing":[127],"nano/microstructured":[129],"via":[132],"electrospinning,":[133],"emerging":[134],"printing":[136],"self-assembly":[138],"techniques,":[139],"nanobiomaterials":[140],"bioactive":[142],"cues":[143],"enhanced":[145],"regeneration.":[148]},"counts_by_year":[{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":15},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":10},{"year":2020,"cited_by_count":11},{"year":2019,"cited_by_count":12},{"year":2018,"cited_by_count":19},{"year":2017,"cited_by_count":20},{"year":2016,"cited_by_count":10},{"year":2015,"cited_by_count":10},{"year":2014,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}