{"id":"https://openalex.org/W2107784598","doi":"https://doi.org/10.1371/journal.pone.0124395","title":"Targets of Wnt/\u00df-Catenin Transcription in Penile Carcinoma","display_name":"Targets of Wnt/\u00df-Catenin Transcription in Penile Carcinoma","publication_year":2015,"publication_date":"2015-04-22","ids":{"openalex":"https://openalex.org/W2107784598","doi":"https://doi.org/10.1371/journal.pone.0124395","mag":"2107784598","pmid":"https://pubmed.ncbi.nlm.nih.gov/25901368","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4406530"},"language":"en","primary_location":{"id":"doi:10.1371/journal.pone.0124395","doi":"https://doi.org/10.1371/journal.pone.0124395","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pone.0124395","pdf_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0124395&type=printable","source":{"id":"https://openalex.org/S202381698","display_name":"PLoS ONE","issn_l":"1932-6203","issn":["1932-6203"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS ONE","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0124395&type=printable","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5072038658","display_name":"Manit Arya","orcid":"https://orcid.org/0000-0002-5122-6881","observed_orcids":["https://orcid.org/0000-0002-5122-6881"]},"institutions":[{"id":"https://openalex.org/I1289784979","display_name":"University College Hospital","ror":"https://ror.org/00wrevg56","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1289784979","https://openalex.org/I1340918713"]},{"id":"https://openalex.org/I166337079","display_name":"Queen Mary University of London","ror":"https://ror.org/026zzn846","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I166337079"]},{"id":"https://openalex.org/I4405264518","display_name":"Barts Cancer Institute","ror":"https://ror.org/0266wrt04","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I166337079","https://openalex.org/I4405264518"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Manit Arya","raw_affiliation_strings":["Division of Surgery, University College Hospital, London, United Kingdom and The Barts Cancer Institute, Queen Mary University of London, London, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Surgery, University College Hospital, London, United Kingdom and The Barts Cancer Institute, Queen Mary University of London, London, United Kingdom","institution_ids":["https://openalex.org/I1289784979","https://openalex.org/I166337079","https://openalex.org/I4405264518"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027951737","display_name":"Christopher Thrasivoulou","orcid":"https://orcid.org/0000-0001-9425-8624","observed_orcids":["https://orcid.org/0000-0001-9425-8624"]},"institutions":[{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Christopher Thrasivoulou","raw_affiliation_strings":["Research Department of Cell and Developmental Biology, The Centre for Cell and Molecular Dynamics, Rockefeller Building, University College London, London, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Department of Cell and Developmental Biology, The Centre for Cell and Molecular Dynamics, Rockefeller Building, University College London, London, United Kingdom","institution_ids":["https://openalex.org/I45129253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057879270","display_name":"Rui Henrique","orcid":"https://orcid.org/0000-0003-3171-4666","observed_orcids":["https://orcid.org/0000-0003-3171-4666"]},"institutions":[{"id":"https://openalex.org/I182534213","display_name":"Universidade do Porto","ror":"https://ror.org/043pwc612","country_code":"PT","type":"education","lineage":["https://openalex.org/I182534213"]},{"id":"https://openalex.org/I4405263123","display_name":"Instituto de Ci\u00eancias Biom\u00e9dicas Albel Salazar","ror":"https://ror.org/02trb6b02","country_code":"PT","type":"education","lineage":["https://openalex.org/I182534213","https://openalex.org/I4405263123"]}],"countries":["PT"],"is_corresponding":false,"raw_author_name":"Rui Henrique","raw_affiliation_strings":["Department of Pathology, Portuguese Oncology Institute and Department of Pathology and Molecular Immunology, Abel Salazar Institute of Biomedical Sciences, University of Porto, Porto, Portugal"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Portuguese Oncology Institute and Department of Pathology and Molecular Immunology, Abel Salazar Institute of Biomedical Sciences, University of Porto, Porto, Portugal","institution_ids":["https://openalex.org/I182534213","https://openalex.org/I4405263123"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Michael Millar","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210164624","display_name":"The Queen's Medical Research Institute","ror":"https://ror.org/059zxg644","country_code":"GB","type":"government","lineage":["https://openalex.org/I4210164624","https://openalex.org/I98677209"]},{"id":"https://openalex.org/I98677209","display_name":"University of Edinburgh","ror":"https://ror.org/01nrxwf90","country_code":"GB","type":"education","lineage":["https://openalex.org/I98677209"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Michael Millar","raw_affiliation_strings":["Queen's Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Queen's Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom","institution_ids":["https://openalex.org/I4210164624","https://openalex.org/I98677209"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090670165","display_name":"Ruth Hamblin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210164624","display_name":"The Queen's Medical Research Institute","ror":"https://ror.org/059zxg644","country_code":"GB","type":"government","lineage":["https://openalex.org/I4210164624","https://openalex.org/I98677209"]},{"id":"https://openalex.org/I98677209","display_name":"University of Edinburgh","ror":"https://ror.org/01nrxwf90","country_code":"GB","type":"education","lineage":["https://openalex.org/I98677209"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Ruth Hamblin","raw_affiliation_strings":["Queen's Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Queen's Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom","institution_ids":["https://openalex.org/I4210164624","https://openalex.org/I98677209"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087688913","display_name":"Reena Davda","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Reena Davda","raw_affiliation_strings":["Prostate Cancer Research Centre, Division of Surgery, University College London, London, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Prostate Cancer Research Centre, Division of Surgery, University College London, London, United Kingdom","institution_ids":["https://openalex.org/I45129253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075286886","display_name":"Kristina Aare","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Kristina Aare","raw_affiliation_strings":["Prostate Cancer Research Centre, Division of Surgery, University College London, London, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Prostate Cancer Research Centre, Division of Surgery, University College London, London, United Kingdom","institution_ids":["https://openalex.org/I45129253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109164028","display_name":"John R. Masters","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"John R. Masters","raw_affiliation_strings":["Prostate Cancer Research Centre, Division of Surgery, University College London, London, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Prostate Cancer Research Centre, Division of Surgery, University College London, London, United Kingdom","institution_ids":["https://openalex.org/I45129253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091901286","display_name":"Calum Thomson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I177639307","display_name":"University of Dundee","ror":"https://ror.org/03h2bxq36","country_code":"GB","type":"education","lineage":["https://openalex.org/I177639307"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Calum Thomson","raw_affiliation_strings":["Dundee Imaging Facility, College of Life Sciences, University of Dundee, Dundee, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dundee Imaging Facility, College of Life Sciences, University of Dundee, Dundee, United Kingdom","institution_ids":["https://openalex.org/I177639307"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085174316","display_name":"As\u0131f Muneer","orcid":"https://orcid.org/0000-0003-2958-1614","observed_orcids":["https://orcid.org/0000-0003-2958-1614"]},"institutions":[{"id":"https://openalex.org/I1289784979","display_name":"University College Hospital","ror":"https://ror.org/00wrevg56","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1289784979","https://openalex.org/I1340918713"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Asif Muneer","raw_affiliation_strings":["Department of Urology, University College Hospital, London, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, University College Hospital, London, United Kingdom","institution_ids":["https://openalex.org/I1289784979"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011795090","display_name":"HITENDRA R.H. PATEL","orcid":"https://orcid.org/0000-0001-8746-2600","observed_orcids":["https://orcid.org/0000-0001-8746-2600"]},"institutions":[{"id":"https://openalex.org/I1298853749","display_name":"University Hospital of North Norway","ror":"https://ror.org/030v5kp38","country_code":"NO","type":"healthcare","lineage":["https://openalex.org/I1298853749","https://openalex.org/I63903255"]}],"countries":["NO"],"is_corresponding":false,"raw_author_name":"Hitendra R. H. Patel","raw_affiliation_strings":["Division of Surgery, Oncology, Urology and Women's Health, University Hospital of Northern Norway, Tromso, Norway"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Surgery, Oncology, Urology and Women's Health, University Hospital of Northern Norway, Tromso, Norway","institution_ids":["https://openalex.org/I1298853749"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5058579733","display_name":"Aamir Ahmed","orcid":"https://orcid.org/0000-0001-7405-5336","observed_orcids":["https://orcid.org/0000-0001-7405-5336"]},"institutions":[{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Aamir Ahmed","raw_affiliation_strings":["Prostate Cancer Research Centre, Division of Surgery, University College London, London, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Prostate Cancer Research Centre, Division of Surgery, University College London, London, United Kingdom","institution_ids":["https://openalex.org/I45129253"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":10,"corresponding_author_ids":["https://openalex.org/A5058579733"],"corresponding_institution_ids":["https://openalex.org/I45129253"],"apc_list":{"value":2382,"currency":"USD","value_usd":2382},"apc_paid":{"value":2382,"currency":"USD","value_usd":2382},"fwci":2.4664,"has_fulltext":true,"cited_by_count":37,"citation_normalized_percentile":{"value":0.87116117,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"10","issue":"4","first_page":"e0124395","last_page":"e0124395"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11713","display_name":"Genital Health and Disease","score":0.6596999764442444,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11713","display_name":"Genital Health and Disease","score":0.6596999764442444,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10929","display_name":"Wnt/\u03b2-catenin signaling in development and cancer","score":0.31839999556541443,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11306","display_name":"Nonmelanoma Skin Cancer Studies","score":0.0024999999441206455,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/penile-squamous-cell-carcinoma","display_name":"penile squamous cell carcinoma","score":0.996999979019165},{"id":"https://openalex.org/keywords/wnt-signaling","display_name":"Wnt signaling","score":0.8830000162124634},{"id":"https://openalex.org/keywords/beta-catenin","display_name":"\u03b2-catenin","score":0.9160000085830688},{"id":"https://openalex.org/keywords/wnt4","display_name":"Wnt4","score":0.921999990940094},{"id":"https://openalex.org/keywords/mmp-7","display_name":"MMP-7","score":0.9909999966621399},{"id":"https://openalex.org/keywords/cyclin-d1","display_name":"cyclin D1","score":0.9929999709129333},{"id":"https://openalex.org/keywords/c-myc","display_name":"c-Myc","score":0.996999979019165},{"id":"https://openalex.org/keywords/protein-colocalization","display_name":"protein colocalization","score":0.8999999761581421},{"id":"https://openalex.org/keywords/tumor-grade","display_name":"tumor grade","score":0.9399999976158142},{"id":"https://openalex.org/keywords/carcinogenesis","display_name":"carcinogenesis","score":0.6610000133514404},{"id":"https://openalex.org/keywords/diagnostic-biomarkers","display_name":"diagnostic biomarkers","score":0.6919999718666077},{"id":"https://openalex.org/keywords/prognostic-stratification","display_name":"prognostic stratification","score":0.9829999804496765}],"concepts":[{"id":"https://openalex.org/C137620995","wikidata":"https://www.wikidata.org/wiki/Q155769","display_name":"Wnt signaling pathway","level":3,"score":0.8841196298599243},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6548100113868713},{"id":"https://openalex.org/C555283112","wikidata":"https://www.wikidata.org/wiki/Q1637543","display_name":"Carcinogenesis","level":3,"score":0.5840566158294678},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.5227144360542297},{"id":"https://openalex.org/C204232928","wikidata":"https://www.wikidata.org/wiki/Q899285","display_name":"Immunohistochemistry","level":2,"score":0.43584734201431274},{"id":"https://openalex.org/C86339819","wikidata":"https://www.wikidata.org/wiki/Q407384","display_name":"Transcription factor","level":3,"score":0.4278075397014618},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.36017799377441406},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.34122592210769653},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.3135891258716583},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.24323126673698425},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.17476415634155273},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.15780174732208252},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.1423124372959137},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.12069040536880493}],"mesh":[{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009363","descriptor_name":"Neoplasm Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D010412","descriptor_name":"Penile Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D010412","descriptor_name":"Penile Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D014158","descriptor_name":"Transcription, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015972","descriptor_name":"Gene Expression Regulation, Neoplastic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016022","descriptor_name":"Case-Control Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016271","descriptor_name":"Proto-Oncogene Proteins c-myc","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D018949","descriptor_name":"Antigens, CD1","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D020783","descriptor_name":"Matrix Metalloproteinase 7","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D051176","descriptor_name":"beta Catenin","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D051176","descriptor_name":"beta Catenin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D060528","descriptor_name":"Wnt4 Protein","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D060528","descriptor_name":"Wnt4 Protein","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D060787","descriptor_name":"Neoplasm Grading","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":10,"locations":[{"id":"doi:10.1371/journal.pone.0124395","doi":"https://doi.org/10.1371/journal.pone.0124395","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pone.0124395","pdf_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0124395&type=printable","source":{"id":"https://openalex.org/S202381698","display_name":"PLoS ONE","issn_l":"1932-6203","issn":["1932-6203"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS ONE","raw_type":"journal-article"},{"id":"pmid:25901368","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25901368","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PloS one","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:4406530","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC4406530/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS One","raw_type":"Text"},{"id":"pmh:oai:pure.ed.ac.uk:openaire/4b85233b-7d43-444e-90f5-7c6efe82472b","doi":null,"is_oa":true,"landing_page_url":"https://www.research.ed.ac.uk/en/publications/4b85233b-7d43-444e-90f5-7c6efe82472b","pdf_url":"https://www.research.ed.ac.uk/files/19508283/Targets_of_wnt_catenin_transcription_in_penile_carcinoma.pdf","source":{"id":"https://openalex.org/S4306400321","display_name":"Edinburgh Research Explorer (University of Edinburgh)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I98677209","host_organization_name":"University of Edinburgh","host_organization_lineage":["https://openalex.org/I98677209"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Arya, M, Thrasivoulou, C, Henrique, R, Millar, M, Hamblin, R, Davda, R, Aare, K, Masters, J R, Thomson, C, Muneer, A, Patel, H R H & Ahmed, A 2015, 'Targets of wnt/\u00df-catenin transcription in penile carcinoma', PLoS ONE, vol. 10, no. 4, pp. e0124395. https://doi.org/10.1371/journal.pone.0124395","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.769.9242","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.769.9242","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/4e/1e/pone.0124395.PMC4406530.pdf","raw_type":"text"},{"id":"pmh:oai:doaj.org/article:90c4f3713f4045b2a18a94fd5ab23d23","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/90c4f3713f4045b2a18a94fd5ab23d23","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS ONE, Vol 10, Iss 4, p e0124395 (2015)","raw_type":"article"},{"id":"pmh:oai:eprints.ucl.ac.uk.OAI2:1470085","doi":null,"is_oa":false,"landing_page_url":"https://discovery.ucl.ac.uk/id/eprint/1470085/","pdf_url":null,"source":{"id":"https://openalex.org/S4306400024","display_name":"UCL Discovery (University College London)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I45129253","host_organization_name":"University College London","host_organization_lineage":["https://openalex.org/I45129253"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS One , 10 (4) , Article e0124395. (2015)","raw_type":"Article"},{"id":"pmh:oai:figshare.com:article/1390831","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/dataset/_Targets_of_Wnt_223_Catenin_Transcription_in_Penile_Carcinoma_/1390831","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Dataset"},{"id":"pmh:oai:kclpure.kcl.ac.uk:openaire/1e444abe-9ce7-4d4b-a928-aafad8f7c5a4","doi":null,"is_oa":true,"landing_page_url":"https://kclpure.kcl.ac.uk/portal/files/123112373/Targets_of_Wnt_Catenin_ARYA_Acc13Mar2015Epub22Apr2015_GOLD_VoR_CC_BY_.PDF","pdf_url":null,"source":{"id":"https://openalex.org/S4306400216","display_name":"Research Portal (King's College London)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I183935753","host_organization_name":"King's College London","host_organization_lineage":["https://openalex.org/I183935753"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Arya, M, Thrasivoulou, C, Henrique, R, Millar, M, Hamblin, R, Davda, R, Aare, K, Masters, J R, Thomson, C, Muneer, A, Patel, H R H & Ahmed, A 2015, 'Targets of Wnt/beta-Catenin Transcription in Penile Carcinoma', PL o S One , vol. 10, no. 4. https://doi.org/10.1371/journal.pone.0124395","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:munin.uit.no:10037/9601","doi":null,"is_oa":true,"landing_page_url":"https://hdl.handle.net/10037/9601","pdf_url":null,"source":{"id":"https://openalex.org/S7407064446","display_name":"NORA - Norwegian Open Research Archives","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1371/journal.pone.0124395","doi":"https://doi.org/10.1371/journal.pone.0124395","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pone.0124395","pdf_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0124395&type=printable","source":{"id":"https://openalex.org/S202381698","display_name":"PLoS ONE","issn_l":"1932-6203","issn":["1932-6203"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS ONE","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9391000270843506,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320320360","display_name":"University of Bristol","ror":"https://ror.org/0524sp257"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2107784598.pdf","grobid_xml":"https://content.openalex.org/works/W2107784598.grobid-xml"},"referenced_works_count":49,"referenced_works":["https://openalex.org/W1517653371","https://openalex.org/W1532880128","https://openalex.org/W1554815317","https://openalex.org/W1670270353","https://openalex.org/W1880424969","https://openalex.org/W1963539523","https://openalex.org/W1965421782","https://openalex.org/W1977874696","https://openalex.org/W1981953083","https://openalex.org/W1984313735","https://openalex.org/W1987708512","https://openalex.org/W1989365861","https://openalex.org/W1990053396","https://openalex.org/W1992595726","https://openalex.org/W2002404925","https://openalex.org/W2005325790","https://openalex.org/W2006419043","https://openalex.org/W2006955307","https://openalex.org/W2010559811","https://openalex.org/W2014923657","https://openalex.org/W2018868898","https://openalex.org/W2023097206","https://openalex.org/W2024849327","https://openalex.org/W2029857102","https://openalex.org/W2042850301","https://openalex.org/W2044127568","https://openalex.org/W2044531485","https://openalex.org/W2069733731","https://openalex.org/W2071642351","https://openalex.org/W2072473431","https://openalex.org/W2079177032","https://openalex.org/W2091956988","https://openalex.org/W2093699479","https://openalex.org/W2105924489","https://openalex.org/W2110278085","https://openalex.org/W2111251544","https://openalex.org/W2117730523","https://openalex.org/W2126490519","https://openalex.org/W2134977493","https://openalex.org/W2143831002","https://openalex.org/W2146812359","https://openalex.org/W2149598894","https://openalex.org/W2152482858","https://openalex.org/W2156924387","https://openalex.org/W2168450176","https://openalex.org/W2183215207","https://openalex.org/W2401850424","https://openalex.org/W2416258921","https://openalex.org/W2470793866"],"related_works":["https://openalex.org/W7099840796","https://openalex.org/W6946500479","https://openalex.org/W4409353786","https://openalex.org/W7160716387","https://openalex.org/W4400825022","https://openalex.org/W2508560490","https://openalex.org/W2357521861","https://openalex.org/W3141067002","https://openalex.org/W892477874","https://openalex.org/W573095460"],"abstract_inverted_index":{"Penile":[0],"squamous":[1],"cell":[2],"carcinoma":[3],"(PeCa)":[4],"is":[5,11,35],"a":[6,32,36,64,124],"rare":[7],"malignancy":[8],"and":[9,42,53,67,78,164,173,184,197],"little":[10],"known":[12],"regarding":[13],"the":[14,27,60,148,160,167,187],"molecular":[15],"mechanisms":[16],"involved":[17],"in":[18,43,80,104,127,145,182],"carcinogenesis":[19],"of":[20,62,70,91,118,159,162,166,186,200],"PeCa.":[21],"The":[22,89],"Wnt":[23,65,93,175,188],"signaling":[24,94,176,189],"pathway,":[25],"with":[26],"transcription":[28,72],"activator":[29],"\u00df-catenin":[30],"as":[31],"major":[33],"transducer,":[34],"key":[37],"cellular":[38],"pathway":[39],"during":[40],"development":[41],"disease,":[44],"particularly":[45],"cancer.":[46],"We":[47],"have":[48],"used":[49,141],"PeCa":[50,105,183],"tissue":[51,83,110,168],"arrays":[52],"multi-fluorophore":[54],"labelled,":[55],"quantitative,":[56],"immunohistochemistry":[57],"to":[58,101,108,131,142],"interrogate":[59],"expression":[61,90],"WNT4,":[63],"ligand,":[66],"three":[68],"targets":[69,194],"Wnt-\u00df-catenin":[71],"activation,":[73],"namely,":[74],"MMP7,":[75],"cyclinD1":[76],"(CD1)":[77],"c-MYC":[79],"141":[81],"penile":[82],"cores":[84],"from":[85],"101":[86],"unique":[87],"samples.":[88],"all":[92,119],"proteins":[95,163,185],"tested":[96],"was":[97],"increased":[98],"by":[99],"1.6":[100],"3":[102],"fold":[103],"samples":[106,115],"compared":[107,130],"control":[109],"(normal":[111],"or":[112],"cancer":[113],"adjacent)":[114],"(p<0.01).":[116],"Expression":[117],"proteins,":[120],"except":[121],"CD1,":[122],"showed":[123],"significant":[125],"decrease":[126],"grade":[128,132],"II":[129],"I":[133,172],"tumors.":[134],"High":[135],"magnification,":[136],"deconvolved":[137],"confocal":[138],"images":[139],"were":[140,154],"measure":[143],"differences":[144,153],"co-localization":[146],"between":[147],"four":[149],"proteins.":[150],"Significant":[151],"(p<0.04-0.0001)":[152],"observed":[155],"for":[156,195],"various":[157],"permutations":[158],"combinations":[161],"state":[165],"(control,":[169],"tumor":[170],"grades":[171],"II).":[174],"may":[177],"play":[178],"an":[179],"important":[180],"role":[181],"network":[190],"could":[191],"be":[192],"useful":[193],"diagnosis":[196],"prognostic":[198],"stratification":[199],"disease.":[201]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":7},{"year":2020,"cited_by_count":5},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":2}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}