{"id":"https://openalex.org/W2107515880","doi":"https://doi.org/10.1093/alcalc/agn109","title":"In vitro Neurogenesis from Neural Progenitor Cells Isolated from the Hippocampus Region of the Brain of Adult Rats Exposed to Ethanol during Early Development through Their Alcohol-Drinking Mothers","display_name":"In vitro Neurogenesis from Neural Progenitor Cells Isolated from the Hippocampus Region of the Brain of Adult Rats Exposed to Ethanol during Early Development through Their Alcohol-Drinking Mothers","publication_year":2009,"publication_date":"2009-01-10","ids":{"openalex":"https://openalex.org/W2107515880","doi":"https://doi.org/10.1093/alcalc/agn109","mag":"2107515880","pmid":"https://pubmed.ncbi.nlm.nih.gov/19136496"},"language":"en","primary_location":{"id":"doi:10.1093/alcalc/agn109","doi":"https://doi.org/10.1093/alcalc/agn109","is_oa":false,"landing_page_url":"https://doi.org/10.1093/alcalc/agn109","pdf_url":null,"source":{"id":"https://openalex.org/S102424854","display_name":"Alcohol and Alcoholism","issn_l":"0735-0414","issn":["0735-0414","1464-3502"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Alcohol and Alcoholism","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101806646","display_name":"Ashok Kumar Singh","orcid":"https://orcid.org/0000-0001-9211-7772","observed_orcids":["https://orcid.org/0000-0001-9211-7772"]},"institutions":[{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"A. K. Singh","raw_affiliation_strings":["Department of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, Twin Cities campus, St Paul, MN 55108, USA. singh001@umn.edu","Department of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, Twin Cities Campus, St. Paul, MN 55108, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, Twin Cities campus, St Paul, MN 55108, USA. singh001@umn.edu","institution_ids":["https://openalex.org/I130238516"]},{"raw_affiliation_string":"Department of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, Twin Cities Campus, St. Paul, MN 55108, USA","institution_ids":["https://openalex.org/I130238516"]}]},{"author_position":"middle","author":{"id":null,"display_name":"S. Gupta","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"S. Gupta","raw_affiliation_strings":["Department of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, Twin Cities Campus, St. Paul, MN 55108, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, Twin Cities Campus, St. Paul, MN 55108, USA","institution_ids":["https://openalex.org/I130238516"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113662402","display_name":"Yunhua Jiang","orcid":"https://orcid.org/0000-0002-7867-4780","observed_orcids":["https://orcid.org/0000-0002-7867-4780"]},"institutions":[{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Y. Jiang","raw_affiliation_strings":["Department of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, Twin Cities Campus, St. Paul, MN 55108, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, Twin Cities Campus, St. Paul, MN 55108, USA","institution_ids":["https://openalex.org/I130238516"]}]},{"author_position":"middle","author":{"id":null,"display_name":"M. Younus","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"M. Younus","raw_affiliation_strings":["Department of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, Twin Cities Campus, St. Paul, MN 55108, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, Twin Cities Campus, St. Paul, MN 55108, USA","institution_ids":["https://openalex.org/I130238516"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5101581594","display_name":"Muhammad Ramzan","orcid":"https://orcid.org/0000-0002-4061-0642","observed_orcids":["https://orcid.org/0000-0002-4061-0642"]},"institutions":[{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"M. Ramzan","raw_affiliation_strings":["Department of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, Twin Cities Campus, St. Paul, MN 55108, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, Twin Cities Campus, St. Paul, MN 55108, USA","institution_ids":["https://openalex.org/I130238516"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5101806646"],"corresponding_institution_ids":["https://openalex.org/I130238516"],"apc_list":{"value":3250,"currency":"GBP","value_usd":4286},"apc_paid":null,"fwci":1.7555,"has_fulltext":false,"cited_by_count":53,"citation_normalized_percentile":{"value":0.82101167,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"44","issue":"2","first_page":"185","last_page":"198"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10608","display_name":"Neurogenesis and neuroplasticity mechanisms","score":0.9829000234603882,"subfield":{"id":"https://openalex.org/subfields/2806","display_name":"Developmental Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10608","display_name":"Neurogenesis and neuroplasticity mechanisms","score":0.9829000234603882,"subfield":{"id":"https://openalex.org/subfields/2806","display_name":"Developmental Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11633","display_name":"Prenatal Substance Exposure Effects","score":0.016100000590085983,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12963","display_name":"Anesthesia and Neurotoxicity Research","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2806","display_name":"Developmental Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/prenatal-alcohol-exposure","display_name":"prenatal alcohol exposure","score":0.824999988079071},{"id":"https://openalex.org/keywords/neural-progenitor-cells","display_name":"neural progenitor cells","score":0.8349999785423279},{"id":"https://openalex.org/keywords/hippocampus","display_name":"hippocampus","score":0.7850000262260437},{"id":"https://openalex.org/keywords/neurogenesis","display_name":"neurogenesis","score":0.7670000195503235},{"id":"https://openalex.org/keywords/neuronal-maturation","display_name":"neuronal maturation","score":0.9490000009536743},{"id":"https://openalex.org/keywords/beta-catenin","display_name":"\u03b2-catenin","score":0.8539999723434448},{"id":"https://openalex.org/keywords/wnt-signaling","display_name":"Wnt signaling","score":0.968999981880188},{"id":"https://openalex.org/keywords/gaba-response","display_name":"GABA response","score":0.8059999942779541},{"id":"https://openalex.org/keywords/glutamate-response","display_name":"glutamate response","score":0.9480000138282776},{"id":"https://openalex.org/keywords/calcium-signaling","display_name":"calcium signaling","score":0.6650000214576721},{"id":"https://openalex.org/keywords/synaptogenesis","display_name":"synaptogenesis","score":0.9330000281333923},{"id":"https://openalex.org/keywords/developmental-programming","display_name":"developmental programming","score":0.3230000138282776}],"concepts":[{"id":"https://openalex.org/C4746552","wikidata":"https://www.wikidata.org/wiki/Q1456827","display_name":"Neurogenesis","level":2,"score":0.7979950904846191},{"id":"https://openalex.org/C136834591","wikidata":"https://www.wikidata.org/wiki/Q2944097","display_name":"Neural stem cell","level":3,"score":0.6348743438720703},{"id":"https://openalex.org/C148762608","wikidata":"https://www.wikidata.org/wiki/Q3748185","display_name":"Hippocampal formation","level":2,"score":0.6153540015220642},{"id":"https://openalex.org/C201750760","wikidata":"https://www.wikidata.org/wiki/Q1896218","display_name":"Progenitor cell","level":3,"score":0.5774776935577393},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5680975914001465},{"id":"https://openalex.org/C2780161600","wikidata":"https://www.wikidata.org/wiki/Q153","display_name":"Ethanol","level":2,"score":0.5679352283477783},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.5620875358581543},{"id":"https://openalex.org/C2781161787","wikidata":"https://www.wikidata.org/wiki/Q48360","display_name":"Hippocampus","level":2,"score":0.5297152996063232},{"id":"https://openalex.org/C2776659692","wikidata":"https://www.wikidata.org/wiki/Q719426","display_name":"Lactation","level":3,"score":0.4632026255130768},{"id":"https://openalex.org/C61174792","wikidata":"https://www.wikidata.org/wiki/Q420510","display_name":"Glutamate receptor","level":3,"score":0.4556562900543213},{"id":"https://openalex.org/C2780655333","wikidata":"https://www.wikidata.org/wiki/Q333203","display_name":"Weaning","level":2,"score":0.42104238271713257},{"id":"https://openalex.org/C137620995","wikidata":"https://www.wikidata.org/wiki/Q155769","display_name":"Wnt signaling pathway","level":3,"score":0.420012891292572},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3982023596763611},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.37587177753448486},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.30197563767433167},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.27468451857566833},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.26831692457199097},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.21548357605934143},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.15368804335594177},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.14564546942710876},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.1157655119895935},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000079","descriptor_name":"Acetaldehyde","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D000431","descriptor_name":"Ethanol","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D000431","descriptor_name":"Ethanol","qualifier_ui":"Q000633","qualifier_name":"toxicity","is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000963","descriptor_name":"Antimetabolites","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001973","descriptor_name":"Bromodeoxyuridine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002452","descriptor_name":"Cell Count","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002454","descriptor_name":"Cell Differentiation","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D002492","descriptor_name":"Central Nervous System Depressants","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D002492","descriptor_name":"Central Nervous System Depressants","qualifier_ui":"Q000633","qualifier_name":"toxicity","is_major_topic":true},{"descriptor_ui":"D003346","descriptor_name":"Corticotropin-Releasing Hormone","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006624","descriptor_name":"Hippocampus","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D006624","descriptor_name":"Hippocampus","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D011247","descriptor_name":"Pregnancy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012313","descriptor_name":"RNA","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D012313","descriptor_name":"RNA","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D013234","descriptor_name":"Stem Cells","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D013569","descriptor_name":"Synapses","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D014162","descriptor_name":"Transfection","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016704","descriptor_name":"Synapsins","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D016704","descriptor_name":"Synapsins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D017207","descriptor_name":"Rats, Sprague-Dawley","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020013","descriptor_name":"Calcium Signaling","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D020013","descriptor_name":"Calcium Signaling","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D020133","descriptor_name":"Reverse Transcriptase Polymerase Chain Reaction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D024202","descriptor_name":"Electrophoretic Mobility Shift Assay","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D049109","descriptor_name":"Cell Proliferation","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D063647","descriptor_name":"Fetal Alcohol Spectrum Disorders","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D063647","descriptor_name":"Fetal Alcohol Spectrum Disorders","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1093/alcalc/agn109","doi":"https://doi.org/10.1093/alcalc/agn109","is_oa":false,"landing_page_url":"https://doi.org/10.1093/alcalc/agn109","pdf_url":null,"source":{"id":"https://openalex.org/S102424854","display_name":"Alcohol and Alcoholism","issn_l":"0735-0414","issn":["0735-0414","1464-3502"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Alcohol and Alcoholism","raw_type":"journal-article"},{"id":"pmid:19136496","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19136496","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Alcohol and alcoholism (Oxford, Oxfordshire)","raw_type":"Journal Article"},{"id":"mag:2291587852","doi":null,"is_oa":false,"landing_page_url":"http://alcalc.oxfordjournals.org/content/alcalc/44/2/185.full.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.979200005531311,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":108,"referenced_works":["https://openalex.org/W66831461","https://openalex.org/W96656099","https://openalex.org/W1603850560","https://openalex.org/W1608349175","https://openalex.org/W1737744869","https://openalex.org/W1936725718","https://openalex.org/W1963940970","https://openalex.org/W1968049209","https://openalex.org/W1968222832","https://openalex.org/W1969892000","https://openalex.org/W1974810606","https://openalex.org/W1975382606","https://openalex.org/W1975391983","https://openalex.org/W1975544734","https://openalex.org/W1976887222","https://openalex.org/W1978891587","https://openalex.org/W1982266611","https://openalex.org/W1983712244","https://openalex.org/W1985122965","https://openalex.org/W1985298323","https://openalex.org/W1985395951","https://openalex.org/W1986105284","https://openalex.org/W1986205528","https://openalex.org/W1990962744","https://openalex.org/W1992359455","https://openalex.org/W1999922261","https://openalex.org/W2001344057","https://openalex.org/W2003432553","https://openalex.org/W2004320707","https://openalex.org/W2006374456","https://openalex.org/W2009947065","https://openalex.org/W2015890115","https://openalex.org/W2016425872","https://openalex.org/W2018414679","https://openalex.org/W2020374419","https://openalex.org/W2023099007","https://openalex.org/W2025385962","https://openalex.org/W2030338901","https://openalex.org/W2033223071","https://openalex.org/W2035252744","https://openalex.org/W2037701234","https://openalex.org/W2039827448","https://openalex.org/W2040692117","https://openalex.org/W2041371211","https://openalex.org/W2041816554","https://openalex.org/W2042154782","https://openalex.org/W2043429907","https://openalex.org/W2043516590","https://openalex.org/W2045945377","https://openalex.org/W2046208726","https://openalex.org/W2046450144","https://openalex.org/W2046501984","https://openalex.org/W2047925020","https://openalex.org/W2050959099","https://openalex.org/W2056564132","https://openalex.org/W2061111257","https://openalex.org/W2062612730","https://openalex.org/W2065737043","https://openalex.org/W2071318481","https://openalex.org/W2072786445","https://openalex.org/W2075798186","https://openalex.org/W2083435127","https://openalex.org/W2083678523","https://openalex.org/W2084081279","https://openalex.org/W2085986920","https://openalex.org/W2087186148","https://openalex.org/W2087404902","https://openalex.org/W2087418408","https://openalex.org/W2088452641","https://openalex.org/W2092964316","https://openalex.org/W2106537812","https://openalex.org/W2106565832","https://openalex.org/W2110722854","https://openalex.org/W2110909720","https://openalex.org/W2112015741","https://openalex.org/W2112877380","https://openalex.org/W2113210947","https://openalex.org/W2117329255","https://openalex.org/W2121849565","https://openalex.org/W2122591546","https://openalex.org/W2124555430","https://openalex.org/W2126356122","https://openalex.org/W2128351119","https://openalex.org/W2131306660","https://openalex.org/W2133769699","https://openalex.org/W2139481908","https://openalex.org/W2139565721","https://openalex.org/W2145050029","https://openalex.org/W2151014587","https://openalex.org/W2153533547","https://openalex.org/W2160164511","https://openalex.org/W2162713173","https://openalex.org/W2163170981","https://openalex.org/W2164425920","https://openalex.org/W2167447234","https://openalex.org/W2168714984","https://openalex.org/W2169508667","https://openalex.org/W2169603159","https://openalex.org/W2170582708","https://openalex.org/W2215753586","https://openalex.org/W2396468088","https://openalex.org/W2402904085","https://openalex.org/W2404160182","https://openalex.org/W2412095815","https://openalex.org/W2500943739","https://openalex.org/W4236670183","https://openalex.org/W4248436058","https://openalex.org/W4253992140"],"related_works":["https://openalex.org/W2291587852","https://openalex.org/W4214634622","https://openalex.org/W3199174875","https://openalex.org/W2013812890","https://openalex.org/W2106537812","https://openalex.org/W2064515004","https://openalex.org/W2066909890","https://openalex.org/W1988075389","https://openalex.org/W28589715","https://openalex.org/W1570708643"],"abstract_inverted_index":{"AIMS:":[0],"This":[1,216],"study":[2],"was":[3,115],"aimed":[4],"to":[5,124,139,148,175,230],"determine":[6],"whether":[7],"ethanol":[8,56,231],"exposure":[9],"during":[10,40],"early":[11,233],"development":[12,234],"altered":[13],"neurogenesis":[14,222],"in":[15,99,118,135,181,207,221,226],"the":[16,46,70,79,155,201,208],"brain":[17],"of":[18,86,127,146,158,173,184,192,197,210],"adult":[19,227],"rats.":[20,120],"METHODS:":[21],"Pregnant":[22],"rats":[23,71,228],"were":[24,72,76,82,96],"given":[25],"either":[26],"ethanol-mixed":[27],"or":[28],"mannose-mixed":[29],"(for":[30],"control)":[31],"rodent":[32],"liquid":[33],"diet":[34,61],"ad":[35,64],"libitum.":[36],"Ethanol":[37],"drinking":[38],"continued":[39],"pregnancy":[41],"and":[42,62,78,93,108,144,154,177,199,213,223],"nursing.":[43],"After":[44],"weaning,":[45],"pups":[47,49,54],"(AC(o):":[48],"from":[50,55],"control":[51],"mothers,":[52],"AE(o):":[53],"exposed":[57,138,229],"mothers)":[58],"received":[59],"normal":[60],"water":[63],"libitum":[65],"for":[66,84],"11":[67],"weeks.":[68],"Then":[69],"anesthetized,":[73],"their":[74,236],"brains":[75],"collected":[77],"hippocampal":[80],"samples":[81],"processed":[83],"isolation":[85],"neural":[87],"progenitor":[88],"cells":[89],"(NPCs).":[90],"AC(o)":[91,121,162],"NPCs":[92,95,186],"AE(o)":[94,185],"sequentially":[97],"grown":[98],"media":[100],"containing":[101],"different":[102],"growth":[103],"factors":[104],"that":[105],"induced":[106],"proliferation":[107],"differentiation.":[109],"RESULTS":[110],"AND":[111],"CONCLUSIONS:":[112],"Neuronal":[113],"maturation":[114],"significantly":[116],"delayed":[117,202],"ethanol-exposed":[119],"NPCs,":[122,163],"up":[123],"day":[125,166,204],"7":[126],"culture,":[128],"exhibited":[129,168],"high":[130,169],"beta-catenin-probe":[131,170,214],"binding,":[132,171],"an":[133,188],"increase":[134,180,206],"Ca(2+)":[136],"when":[137],"gamma-amino":[140],"butyric":[141],"acid":[142],"(GABA)":[143],"lack":[145,172],"response":[147,174],"glutamate":[149],"(Glu)":[150],"exposure.":[151],"beta-Catenin-probe":[152],"binding":[153],"stimulatory":[156,190,195],"effects":[157,191,196],"GABA":[159,176],"declined":[160],"thereafter.":[161],"at":[164,232],"culture":[165],"29,":[167],"elevated":[178],"Glu-induced":[179],"Ca(2+i).":[182],"Cultures":[183],"showed":[187],"amplified":[189],"GABA,":[193],"attenuated":[194,200],"Glu":[198],"(culture":[203],"29)":[205],"expression":[209],"Wnt":[211],"proteins":[212],"binding.":[215],"suggests":[217],"a":[218],"significant":[219],"alteration":[220],"synapse":[224],"formation":[225],"through":[235],"alcohol-drinking":[237],"mothers.":[238]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":7},{"year":2015,"cited_by_count":6},{"year":2014,"cited_by_count":4},{"year":2013,"cited_by_count":4},{"year":2012,"cited_by_count":4}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}