{"id":"https://openalex.org/W2107440833","doi":"https://doi.org/10.1093/nar/gkq433","title":"Convergent donor and acceptor substrate utilization among kinase ribozymes","display_name":"Convergent donor and acceptor substrate utilization among kinase ribozymes","publication_year":2010,"publication_date":"2010-05-28","ids":{"openalex":"https://openalex.org/W2107440833","doi":"https://doi.org/10.1093/nar/gkq433","mag":"2107440833","pmid":"https://pubmed.ncbi.nlm.nih.gov/20511589","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2965213"},"language":"en","primary_location":{"id":"doi:10.1093/nar/gkq433","doi":"https://doi.org/10.1093/nar/gkq433","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkq433","pdf_url":null,"source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1093/nar/gkq433","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5070183152","display_name":"Elisa Biondi","orcid":"https://orcid.org/0000-0002-3660-2607","observed_orcids":["https://orcid.org/0000-0002-3660-2607"]},"institutions":[{"id":"https://openalex.org/I76835614","display_name":"University of Missouri","ror":"https://ror.org/02ymw8z06","country_code":"US","type":"education","lineage":["https://openalex.org/I76835614"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Elisa Biondi","raw_affiliation_strings":["Department of Molecular Microbiology and Immunology, Bond Life Sciences Center, University of Missouri, Columbia, MO 65211, USA. biondie@missouri.edu","Department of Molecular Microbiology and Immunology, Bond Life Sciences Center, University of Missouri, Columbia, MO 65211, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Microbiology and Immunology, Bond Life Sciences Center, University of Missouri, Columbia, MO 65211, USA. biondie@missouri.edu","institution_ids":["https://openalex.org/I76835614"]},{"raw_affiliation_string":"Department of Molecular Microbiology and Immunology, Bond Life Sciences Center, University of Missouri, Columbia, MO 65211, USA","institution_ids":["https://openalex.org/I76835614"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028783197","display_name":"David G. Nickens","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210119109","display_name":"Indiana University Bloomington","ror":"https://ror.org/02k40bc56","country_code":"US","type":"education","lineage":["https://openalex.org/I4210119109","https://openalex.org/I592451"]},{"id":"https://openalex.org/I592451","display_name":"Indiana University","ror":"https://ror.org/01kg8sb98","country_code":"US","type":"education","lineage":["https://openalex.org/I592451"]},{"id":"https://openalex.org/I76835614","display_name":"University of Missouri","ror":"https://ror.org/02ymw8z06","country_code":"US","type":"education","lineage":["https://openalex.org/I76835614"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David G. Nickens","raw_affiliation_strings":["Department of Molecular Microbiology and Immunology, 2 Department of Biochemistry, 3 Bond Life Sciences Center, University of Missouri, Columbia, MO 65211, 4 Department of Chemistry and 5 Department of Biology, Indiana University, Bloomington, IN 47401, USA","University of Missouri, Columbia, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Microbiology and Immunology, 2 Department of Biochemistry, 3 Bond Life Sciences Center, University of Missouri, Columbia, MO 65211, 4 Department of Chemistry and 5 Department of Biology, Indiana University, Bloomington, IN 47401, USA","institution_ids":["https://openalex.org/I4210119109","https://openalex.org/I592451","https://openalex.org/I76835614"]},{"raw_affiliation_string":"University of Missouri, Columbia, United States","institution_ids":["https://openalex.org/I76835614"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042128403","display_name":"Samantha Warren","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210119109","display_name":"Indiana University Bloomington","ror":"https://ror.org/02k40bc56","country_code":"US","type":"education","lineage":["https://openalex.org/I4210119109","https://openalex.org/I592451"]},{"id":"https://openalex.org/I592451","display_name":"Indiana University","ror":"https://ror.org/01kg8sb98","country_code":"US","type":"education","lineage":["https://openalex.org/I592451"]},{"id":"https://openalex.org/I76835614","display_name":"University of Missouri","ror":"https://ror.org/02ymw8z06","country_code":"US","type":"education","lineage":["https://openalex.org/I76835614"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Samantha Warren","raw_affiliation_strings":["Department of Molecular Microbiology and Immunology, 2 Department of Biochemistry, 3 Bond Life Sciences Center, University of Missouri, Columbia, MO 65211, 4 Department of Chemistry and 5 Department of Biology, Indiana University, Bloomington, IN 47401, USA","University of Missouri, Columbia, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Microbiology and Immunology, 2 Department of Biochemistry, 3 Bond Life Sciences Center, University of Missouri, Columbia, MO 65211, 4 Department of Chemistry and 5 Department of Biology, Indiana University, Bloomington, IN 47401, USA","institution_ids":["https://openalex.org/I4210119109","https://openalex.org/I592451","https://openalex.org/I76835614"]},{"raw_affiliation_string":"University of Missouri, Columbia, United States","institution_ids":["https://openalex.org/I76835614"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069255477","display_name":"Dayal Saran","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210119109","display_name":"Indiana University Bloomington","ror":"https://ror.org/02k40bc56","country_code":"US","type":"education","lineage":["https://openalex.org/I4210119109","https://openalex.org/I592451"]},{"id":"https://openalex.org/I592451","display_name":"Indiana University","ror":"https://ror.org/01kg8sb98","country_code":"US","type":"education","lineage":["https://openalex.org/I592451"]},{"id":"https://openalex.org/I76835614","display_name":"University of Missouri","ror":"https://ror.org/02ymw8z06","country_code":"US","type":"education","lineage":["https://openalex.org/I76835614"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dayal Saran","raw_affiliation_strings":["Department of Molecular Microbiology and Immunology, 2 Department of Biochemistry, 3 Bond Life Sciences Center, University of Missouri, Columbia, MO 65211, 4 Department of Chemistry and 5 Department of Biology, Indiana University, Bloomington, IN 47401, USA","University of Missouri, Columbia, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Microbiology and Immunology, 2 Department of Biochemistry, 3 Bond Life Sciences Center, University of Missouri, Columbia, MO 65211, 4 Department of Chemistry and 5 Department of Biology, Indiana University, Bloomington, IN 47401, USA","institution_ids":["https://openalex.org/I4210119109","https://openalex.org/I592451","https://openalex.org/I76835614"]},{"raw_affiliation_string":"University of Missouri, Columbia, United States","institution_ids":["https://openalex.org/I76835614"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5018442903","display_name":"Donald H. Burke","orcid":"https://orcid.org/0000-0001-6513-8391","observed_orcids":["https://orcid.org/0000-0001-6513-8391"]},"institutions":[{"id":"https://openalex.org/I4210119109","display_name":"Indiana University Bloomington","ror":"https://ror.org/02k40bc56","country_code":"US","type":"education","lineage":["https://openalex.org/I4210119109","https://openalex.org/I592451"]},{"id":"https://openalex.org/I592451","display_name":"Indiana University","ror":"https://ror.org/01kg8sb98","country_code":"US","type":"education","lineage":["https://openalex.org/I592451"]},{"id":"https://openalex.org/I76835614","display_name":"University of Missouri","ror":"https://ror.org/02ymw8z06","country_code":"US","type":"education","lineage":["https://openalex.org/I76835614"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Donald H. Burke","raw_affiliation_strings":["Department of Molecular Microbiology and Immunology, 2 Department of Biochemistry, 3 Bond Life Sciences Center, University of Missouri, Columbia, MO 65211, 4 Department of Chemistry and 5 Department of Biology, Indiana University, Bloomington, IN 47401, USA","University of Missouri, Columbia, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Microbiology and Immunology, 2 Department of Biochemistry, 3 Bond Life Sciences Center, University of Missouri, Columbia, MO 65211, 4 Department of Chemistry and 5 Department of Biology, Indiana University, Bloomington, IN 47401, USA","institution_ids":["https://openalex.org/I4210119109","https://openalex.org/I592451","https://openalex.org/I76835614"]},{"raw_affiliation_string":"University of Missouri, Columbia, United States","institution_ids":["https://openalex.org/I76835614"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5018442903","https://openalex.org/A5070183152"],"corresponding_institution_ids":["https://openalex.org/I4210119109","https://openalex.org/I592451","https://openalex.org/I76835614"],"apc_list":{"value":3992,"currency":"USD","value_usd":3992},"apc_paid":{"value":3992,"currency":"USD","value_usd":3992},"fwci":1.0765,"has_fulltext":false,"cited_by_count":19,"citation_normalized_percentile":{"value":0.74038747,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"38","issue":"19","first_page":"6785","last_page":"6795"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.9901999831199646,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.9901999831199646,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10432","display_name":"DNA and Nucleic Acid Chemistry","score":0.0052999998442828655,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12827","display_name":"Biochemical and Molecular Research","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/atpgammas","display_name":"ATP gamma S","score":0.5019999742507935},{"id":"https://openalex.org/keywords/gtpgammas","display_name":"GTP gamma S","score":0.9980000257492065}],"concepts":[{"id":"https://openalex.org/C76346623","wikidata":"https://www.wikidata.org/wiki/Q205858","display_name":"Ribozyme","level":4,"score":0.9329015612602234},{"id":"https://openalex.org/C512185932","wikidata":"https://www.wikidata.org/wiki/Q28745","display_name":"Nucleotide","level":3,"score":0.6773325204849243},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6483972072601318},{"id":"https://openalex.org/C2777995097","wikidata":"https://www.wikidata.org/wiki/Q422462","display_name":"Guanosine","level":2,"score":0.5137122869491577},{"id":"https://openalex.org/C41183919","wikidata":"https://www.wikidata.org/wiki/Q423026","display_name":"Active site","level":3,"score":0.47050589323043823},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.4635348320007324},{"id":"https://openalex.org/C11960822","wikidata":"https://www.wikidata.org/wiki/Q242736","display_name":"Phosphorylation","level":2,"score":0.4345320463180542},{"id":"https://openalex.org/C2781253882","wikidata":"https://www.wikidata.org/wiki/Q770860","display_name":"Thio-","level":2,"score":0.42996761202812195},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.4176425635814667},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.24950706958770752},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.22938868403434753},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.20298299193382263},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.1579877734184265}],"mesh":[{"descriptor_ui":"D000255","descriptor_name":"Adenosine Triphosphate","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":false},{"descriptor_ui":"D000255","descriptor_name":"Adenosine Triphosphate","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007700","descriptor_name":"Kinetics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009690","descriptor_name":"Nucleic Acid Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010766","descriptor_name":"Phosphorylation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010770","descriptor_name":"Phosphotransferases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D010770","descriptor_name":"Phosphotransferases","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D013379","descriptor_name":"Substrate Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016244","descriptor_name":"Guanosine 5'-O-(3-Thiotriphosphate)","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D016337","descriptor_name":"RNA, Catalytic","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D016337","descriptor_name":"RNA, Catalytic","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D055162","descriptor_name":"Biocatalysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":6,"locations":[{"id":"doi:10.1093/nar/gkq433","doi":"https://doi.org/10.1093/nar/gkq433","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkq433","pdf_url":null,"source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:1778866","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2965213","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:2965213","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2965213","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Res","raw_type":"Text"},{"id":"pmid:20511589","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20511589","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic acids research","raw_type":"Journal Article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.351.3853","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.351.3853","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/a7/5f/Nucleic_Acids_Res_2010_Oct_28_38(19)_6785-6795.tar.gz","raw_type":"text"},{"id":"pmh:oai:open-archive.highwire.org:nar:38/19/6785","doi":null,"is_oa":false,"landing_page_url":"http://nar.oxfordjournals.org/cgi/content/short/38/19/6785","pdf_url":null,"source":{"id":"https://openalex.org/S4406923041","display_name":"HighWire Press Open Archive","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"TEXT"}],"best_oa_location":{"id":"doi:10.1093/nar/gkq433","doi":"https://doi.org/10.1093/nar/gkq433","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkq433","pdf_url":null,"source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":62,"referenced_works":["https://openalex.org/W1487241221","https://openalex.org/W1612553237","https://openalex.org/W1922238526","https://openalex.org/W1964261732","https://openalex.org/W1967803927","https://openalex.org/W1970478438","https://openalex.org/W1971168553","https://openalex.org/W1976082767","https://openalex.org/W1977233251","https://openalex.org/W1980410097","https://openalex.org/W1980461160","https://openalex.org/W1985250489","https://openalex.org/W1988349747","https://openalex.org/W1988409793","https://openalex.org/W1992966156","https://openalex.org/W1998894699","https://openalex.org/W2002511038","https://openalex.org/W2009138444","https://openalex.org/W2013795932","https://openalex.org/W2015654189","https://openalex.org/W2019309102","https://openalex.org/W2021688648","https://openalex.org/W2024377181","https://openalex.org/W2025653565","https://openalex.org/W2026368455","https://openalex.org/W2033046940","https://openalex.org/W2040592774","https://openalex.org/W2045058197","https://openalex.org/W2046880909","https://openalex.org/W2047292646","https://openalex.org/W2048602141","https://openalex.org/W2050603450","https://openalex.org/W2053237622","https://openalex.org/W2054292245","https://openalex.org/W2056572820","https://openalex.org/W2060841907","https://openalex.org/W2073925095","https://openalex.org/W2079794747","https://openalex.org/W2080371573","https://openalex.org/W2082844730","https://openalex.org/W2084002725","https://openalex.org/W2085488263","https://openalex.org/W2087177471","https://openalex.org/W2091139369","https://openalex.org/W2091535033","https://openalex.org/W2091982417","https://openalex.org/W2095239103","https://openalex.org/W2097654784","https://openalex.org/W2106769579","https://openalex.org/W2112939263","https://openalex.org/W2118203264","https://openalex.org/W2128066019","https://openalex.org/W2132589661","https://openalex.org/W2141157874","https://openalex.org/W2147675827","https://openalex.org/W2153461732","https://openalex.org/W2154379876","https://openalex.org/W2159859043","https://openalex.org/W2162296614","https://openalex.org/W2168048890","https://openalex.org/W2320322570","https://openalex.org/W2336152627"],"related_works":["https://openalex.org/W2085488263","https://openalex.org/W2143265630","https://openalex.org/W2009138444","https://openalex.org/W1948103171","https://openalex.org/W2048602141","https://openalex.org/W2152559557","https://openalex.org/W2116564713","https://openalex.org/W1986863698","https://openalex.org/W839402279","https://openalex.org/W7098106346"],"abstract_inverted_index":{"Accommodation":[0],"of":[1,11,22,102,116,140,172],"donor":[2,23,71,103,122,147],"and":[3,29,74,126],"acceptor":[4],"substrates":[5],"is":[6,31],"critical":[7,107],"to":[8,109,157],"the":[9,36,113,117,132,159,163,173],"catalysis":[10],"(thio)phosphoryl":[12],"group":[13],"transfer,":[14],"but":[15,170],"there":[16,30],"has":[17],"been":[18],"no":[19,129],"systematic":[20],"study":[21],"nucleotide":[24,72,96,123],"recognition":[25,73,104,110],"by":[26,112],"kinase":[27,194],"ribozymes,":[28],"relatively":[32],"little":[33,127],"known":[34],"about":[35],"structural":[37,185,191],"requirements":[38],"for":[39,57,79,89,166,193],"phosphorylating":[40],"internal":[41,182],"2'OH.":[42],"To":[43],"address":[44],"these":[45],"questions,":[46],"new":[47],"self-phosphorylating":[48],"ribozymes":[49,137,153],"were":[50,64,77],"selected":[51],"that":[52],"utilize":[53],"ATP(gammaS)":[54],"or":[55,128,145],"GTP(gammaS)":[56],"2'OH":[58],"(thio)phosphorylation.":[59],"Eight":[60],"independent":[61],"sequence":[62],"families":[63],"identified":[65,187],"among":[66],"57":[67],"sequenced":[68],"isolates.":[69],"Kinetics,":[70],"secondary":[75],"structures":[76],"analyzed":[78],"representatives":[80],"from":[81,121,131],"each":[82],"family.":[83],"Each":[84],"ribozyme":[85,195],"was":[86],"highly":[87],"specific":[88],"its":[90],"cognate":[91],"donor.":[92],"Competition":[93],"assays":[94],"with":[95,106,143],"analogs":[97],"showed":[98,138],"a":[99],"remarkable":[100],"convergence":[101],"requirements,":[105],"contributions":[108,120],"provided":[111],"Watson-Crick":[114],"face":[115],"nucleobase,":[118],"lesser":[119],"ribose":[124],"hydroxyls,":[125],"contribution":[130],"Hoogsteen":[133],"face.":[134],"Importantly,":[135],"most":[136,151],"evidence":[139],"significant":[141],"interaction":[142],"one":[144,171],"more":[146],"phosphates,":[148],"suggesting":[149],"that-unlike":[150],"aptamers-these":[152],"use":[154],"phosphate":[155,161],"interactions":[156],"orient":[158],"gamma":[160],"within":[162,181],"active":[164,196],"site":[165],"in-line":[167],"displacement.":[168],"All":[169],"mapped":[174],"(thio)phosphorylation":[175],"sites":[176],"are":[177],"on":[178],"unpaired":[179],"guanosines":[180],"bulges.":[183],"Comparative":[184],"analysis":[186],"three":[188],"loosely-defined":[189],"consensus":[190],"motifs":[192],"sites.":[197]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2016,"cited_by_count":3},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":4}],"updated_date":"2026-11-05T12:25:35.769452","created_date":"2016-06-24T00:00:00"}