{"id":"https://openalex.org/W2107072249","doi":"https://doi.org/10.1016/s0002-9610(97)00231-6","title":"Gut Bacterial Translocation during Total Parenteral Nutrition in Experimental Rats and Its Countermeasure","display_name":"Gut Bacterial Translocation during Total Parenteral Nutrition in Experimental Rats and Its Countermeasure","publication_year":1998,"publication_date":"1998-01-01","ids":{"openalex":"https://openalex.org/W2107072249","doi":"https://doi.org/10.1016/s0002-9610(97)00231-6","mag":"2107072249","pmid":"https://pubmed.ncbi.nlm.nih.gov/9445237"},"language":"en","primary_location":{"id":"doi:10.1016/s0002-9610(97)00231-6","doi":"https://doi.org/10.1016/s0002-9610(97)00231-6","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0002-9610(97)00231-6","pdf_url":null,"source":{"id":"https://openalex.org/S101510409","display_name":"The American Journal of Surgery","issn_l":"0002-9610","issn":["0002-9610","1879-1883"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American Journal of Surgery","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5076728126","display_name":"Hisao Nakasaki","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210114625","display_name":"Shonan Oiso Hospital","ror":"https://ror.org/02dx51s73","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210114625"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Hisao Nakasaki","raw_affiliation_strings":["Department of Surgery, Tokai University Oiso Hospital, Kanagawa, Japan","Department of Surgery (HN), Tokai University Oiso Hospital, Oiso, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, Tokai University Oiso Hospital, Kanagawa, Japan","institution_ids":["https://openalex.org/I4210114625"]},{"raw_affiliation_string":"Department of Surgery (HN), Tokai University Oiso Hospital, Oiso, Japan","institution_ids":["https://openalex.org/I4210114625"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061332860","display_name":"Toshio Mitomi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1314466530","display_name":"Tokai University","ror":"https://ror.org/01p7qe739","country_code":"JP","type":"education","lineage":["https://openalex.org/I1314466530"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Toshio Mitomi","raw_affiliation_strings":["Department of Surgery (TM, KF), Tokai University School of Medicine, Oiso, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery (TM, KF), Tokai University School of Medicine, Oiso, Japan","institution_ids":["https://openalex.org/I1314466530"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028923848","display_name":"Tomoo Tajima","orcid":"https://orcid.org/0009-0003-2426-6073","observed_orcids":["https://orcid.org/0009-0003-2426-6073"]},"institutions":[{"id":"https://openalex.org/I4387153864","display_name":"Tokai University Tokyo Hospital","ror":"https://ror.org/034kd8j82","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4387153864"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Tomoo Tajima","raw_affiliation_strings":["Department of Surgery (TT), Tokai University Tokyo Hospital, Oiso, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery (TT), Tokai University Tokyo Hospital, Oiso, Japan","institution_ids":["https://openalex.org/I4387153864"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109180795","display_name":"Nobuhiko Ohnishi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1314466530","display_name":"Tokai University","ror":"https://ror.org/01p7qe739","country_code":"JP","type":"education","lineage":["https://openalex.org/I1314466530"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Nobuhiko Ohnishi","raw_affiliation_strings":["Department of Infectious Diseases (NO), Tokai University School of Medicine, Oiso, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Infectious Diseases (NO), Tokai University School of Medicine, Oiso, Japan","institution_ids":["https://openalex.org/I1314466530"]}]},{"author_position":"last","author":{"id":null,"display_name":"Koichi Fujii","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1314466530","display_name":"Tokai University","ror":"https://ror.org/01p7qe739","country_code":"JP","type":"education","lineage":["https://openalex.org/I1314466530"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Koichi Fujii","raw_affiliation_strings":["Department of Surgery (TM, KF), Tokai University School of Medicine, Oiso, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery (TM, KF), Tokai University School of Medicine, Oiso, Japan","institution_ids":["https://openalex.org/I1314466530"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5076728126"],"corresponding_institution_ids":["https://openalex.org/I4210114625"],"apc_list":{"value":3830,"currency":"USD","value_usd":3830},"apc_paid":null,"fwci":2.2543,"has_fulltext":false,"cited_by_count":40,"citation_normalized_percentile":{"value":0.8663091,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"175","issue":"1","first_page":"38","last_page":"43"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10858","display_name":"Clinical Nutrition and Gastroenterology","score":0.9937000274658203,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10858","display_name":"Clinical Nutrition and Gastroenterology","score":0.9937000274658203,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10365","display_name":"Gastrointestinal motility and disorders","score":0.001500000013038516,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10371","display_name":"Immune Response and Inflammation","score":0.0010999999940395355,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/total-parenteral-nutrition","display_name":"total parenteral nutrition","score":0.8270000219345093},{"id":"https://openalex.org/keywords/bacterial-translocation","display_name":"bacterial translocation","score":0.9350000023841858},{"id":"https://openalex.org/keywords/gut-associated-lymphoid-tissue","display_name":"gut-associated lymphoid tissue","score":0.9710000157356262},{"id":"https://openalex.org/keywords/psk","display_name":"PSK","score":0.7590000033378601},{"id":"https://openalex.org/keywords/proteoglycans","display_name":"proteoglycans","score":0.9110000133514404},{"id":"https://openalex.org/keywords/biological-response-modifiers","display_name":"biological response modifiers","score":0.8410000205039978},{"id":"https://openalex.org/keywords/secretory-iga","display_name":"secretory IgA","score":0.8560000061988831},{"id":"https://openalex.org/keywords/mesenteric-lymph-nodes","display_name":"mesenteric lymph nodes","score":0.8849999904632568},{"id":"https://openalex.org/keywords/peyer-s-patches","display_name":"Peyer's patches","score":0.9300000071525574},{"id":"https://openalex.org/keywords/local-immunity","display_name":"local immunity","score":0.6480000019073486},{"id":"https://openalex.org/keywords/interleukin-2","display_name":"interleukin-2","score":0.8349999785423279},{"id":"https://openalex.org/keywords/t-helper-cells","display_name":"T helper cells","score":0.7409999966621399},{"id":"https://openalex.org/keywords/mhc-class-i-and-ii","display_name":"MHC class I and II","score":0.8700000047683716}],"concepts":[{"id":"https://openalex.org/C2779237934","wikidata":"https://www.wikidata.org/wiki/Q7643652","display_name":"Mesenteric lymph nodes","level":3,"score":0.8078750371932983},{"id":"https://openalex.org/C138626823","wikidata":"https://www.wikidata.org/wiki/Q916504","display_name":"Chromosomal translocation","level":3,"score":0.6495926976203918},{"id":"https://openalex.org/C2779720271","wikidata":"https://www.wikidata.org/wiki/Q179422","display_name":"Lymph","level":2,"score":0.5149596333503723},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5116434693336487},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.47838249802589417},{"id":"https://openalex.org/C204232928","wikidata":"https://www.wikidata.org/wiki/Q899285","display_name":"Immunohistochemistry","level":2,"score":0.47615620493888855},{"id":"https://openalex.org/C2779341262","wikidata":"https://www.wikidata.org/wiki/Q182581","display_name":"Immunity","level":3,"score":0.4558064937591553},{"id":"https://openalex.org/C2780512811","wikidata":"https://www.wikidata.org/wiki/Q11829360","display_name":"Gastrointestinal tract","level":2,"score":0.45525726675987244},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.38290145993232727},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.35693907737731934},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.34897375106811523},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2976266145706177},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000284","descriptor_name":"Administration, Oral","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000911","descriptor_name":"Antibodies, Monoclonal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001420","descriptor_name":"Bacteria, Aerobic","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D001421","descriptor_name":"Bacteria, Anaerobic","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D001431","descriptor_name":"Bacteriological Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001646","descriptor_name":"Bile","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D003627","descriptor_name":"Data Interpretation, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004797","descriptor_name":"Enzyme-Linked Immunosorbent Assay","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006652","descriptor_name":"Histological Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007071","descriptor_name":"Immunoglobulin A, Secretory","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D007071","descriptor_name":"Immunoglobulin A, Secretory","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D007150","descriptor_name":"Immunohistochemistry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007376","descriptor_name":"Interleukin-2","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D007422","descriptor_name":"Intestines","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D007422","descriptor_name":"Intestines","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":true},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D008198","descriptor_name":"Lymph Nodes","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D008198","descriptor_name":"Lymph Nodes","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D008221","descriptor_name":"Lymphoid Tissue","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D008221","descriptor_name":"Lymphoid Tissue","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D008285","descriptor_name":"Major Histocompatibility Complex","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008643","descriptor_name":"Mesentery","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D008643","descriptor_name":"Mesentery","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D010289","descriptor_name":"Parenteral Nutrition, Total","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D010581","descriptor_name":"Peyer's Patches","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D010581","descriptor_name":"Peyer's Patches","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D011169","descriptor_name":"Portal Vein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011509","descriptor_name":"Proteoglycans","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D011509","descriptor_name":"Proteoglycans","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D013154","descriptor_name":"Spleen","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D013234","descriptor_name":"Stem Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017208","descriptor_name":"Rats, Wistar","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D046508","descriptor_name":"Culture Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1016/s0002-9610(97)00231-6","doi":"https://doi.org/10.1016/s0002-9610(97)00231-6","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0002-9610(97)00231-6","pdf_url":null,"source":{"id":"https://openalex.org/S101510409","display_name":"The American Journal of Surgery","issn_l":"0002-9610","issn":["0002-9610","1879-1883"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American Journal of Surgery","raw_type":"journal-article"},{"id":"pmid:9445237","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9445237","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American journal of surgery","raw_type":"Comparative Study"},{"id":"mag:3200705919","doi":null,"is_oa":false,"landing_page_url":"http://www.infona.pl/resource/bwmeta1.element.elsevier-74773974-6e75-3e8f-93ae-4c11fd2cb4c8","pdf_url":null,"source":{"id":"https://openalex.org/S101510409","display_name":"The American Journal of Surgery","issn_l":"0002-9610","issn":["0002-9610","1879-1883"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"The American Journal of Surgery","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":28,"referenced_works":["https://openalex.org/W8587632","https://openalex.org/W112984908","https://openalex.org/W322070215","https://openalex.org/W1777407783","https://openalex.org/W1980613460","https://openalex.org/W1987673472","https://openalex.org/W2003158706","https://openalex.org/W2011402444","https://openalex.org/W2019460870","https://openalex.org/W2026072775","https://openalex.org/W2029889596","https://openalex.org/W2034160802","https://openalex.org/W2034636095","https://openalex.org/W2035142804","https://openalex.org/W2043686140","https://openalex.org/W2044615898","https://openalex.org/W2057553935","https://openalex.org/W2072304449","https://openalex.org/W2076213629","https://openalex.org/W2077963610","https://openalex.org/W2088295190","https://openalex.org/W2125376637","https://openalex.org/W2133851674","https://openalex.org/W2162523534","https://openalex.org/W2339081458","https://openalex.org/W2396085907","https://openalex.org/W2404266960","https://openalex.org/W2419360016"],"related_works":["https://openalex.org/W2058934302","https://openalex.org/W81494798","https://openalex.org/W2386103533","https://openalex.org/W1995131286","https://openalex.org/W2409380895","https://openalex.org/W2489236255","https://openalex.org/W3200705919","https://openalex.org/W6922083932","https://openalex.org/W2409040095","https://openalex.org/W2069636061"],"abstract_inverted_index":null,"counts_by_year":[{"year":2024,"cited_by_count":2},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}