{"id":"https://openalex.org/W2106995992","doi":"https://doi.org/10.1002/9780470682531.pat0363","title":"Biomimetic Fe ( II ) Chemistry and Synthetic Studies on Antimalarial and Antitumour Endoperoxides","display_name":"Biomimetic Fe ( II ) Chemistry and Synthetic Studies on Antimalarial and Antitumour Endoperoxides","publication_year":2009,"publication_date":"2009-12-14","ids":{"openalex":"https://openalex.org/W2106995992","doi":"https://doi.org/10.1002/9780470682531.pat0363","mag":"2106995992"},"language":"en","primary_location":{"id":"doi:10.1002/9780470682531.pat0363","doi":"https://doi.org/10.1002/9780470682531.pat0363","is_oa":false,"landing_page_url":"https://doi.org/10.1002/9780470682531.pat0363","pdf_url":null,"source":{"id":"https://openalex.org/S4210173804","display_name":"Patai's chemistry of functional groups","issn_l":"2042-5643","issn":["2042-5643","2042-5651"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PATAI'S Chemistry of Functional Groups","raw_type":"other"},"volume":{"id":"https://openalex.org/W4252681471","display_name":"PATAI'S Chemistry of Functional Groups"},"type":"other","is_traditional":false,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5030009340","display_name":"Paul M. O\u2019Neill","orcid":"https://orcid.org/0000-0003-4338-0317","observed_orcids":["https://orcid.org/0000-0003-4338-0317"]},"institutions":[{"id":"https://openalex.org/I146655781","display_name":"University of Liverpool","ror":"https://ror.org/04xs57h96","country_code":"GB","type":"education","lineage":["https://openalex.org/I146655781"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Paul M. O'Neill","raw_affiliation_strings":["University of Liverpool, Department of Chemistry, The Robert Robinson Laboratories, Liverpool, UK, L69 7ZD","University of Liverpool Department of Chemistry The Robert Robinson Laboratories Liverpool UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Liverpool, Department of Chemistry, The Robert Robinson Laboratories, Liverpool, UK, L69 7ZD","institution_ids":["https://openalex.org/I146655781"]},{"raw_affiliation_string":"University of Liverpool Department of Chemistry The Robert Robinson Laboratories Liverpool UK","institution_ids":["https://openalex.org/I146655781"]}]},{"author_position":"middle","author":{"id":null,"display_name":"James Chadwick","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I146655781","display_name":"University of Liverpool","ror":"https://ror.org/04xs57h96","country_code":"GB","type":"education","lineage":["https://openalex.org/I146655781"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"James Chadwick","raw_affiliation_strings":["University of Liverpool, Department of Chemistry, The Robert Robinson Laboratories, Liverpool, UK, L69 7ZD","University of Liverpool Department of Chemistry The Robert Robinson Laboratories Liverpool UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Liverpool, Department of Chemistry, The Robert Robinson Laboratories, Liverpool, UK, L69 7ZD","institution_ids":["https://openalex.org/I146655781"]},{"raw_affiliation_string":"University of Liverpool Department of Chemistry The Robert Robinson Laboratories Liverpool UK","institution_ids":["https://openalex.org/I146655781"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5038788848","display_name":"Sarah Louise Rawe","orcid":"https://orcid.org/0000-0003-0940-8371","observed_orcids":["https://orcid.org/0000-0003-0940-8371"]},"institutions":[{"id":"https://openalex.org/I146655781","display_name":"University of Liverpool","ror":"https://ror.org/04xs57h96","country_code":"GB","type":"education","lineage":["https://openalex.org/I146655781"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Sarah L. Rawe","raw_affiliation_strings":["University of Liverpool, Department of Chemistry, The Robert Robinson Laboratories, Liverpool, UK, L69 7ZD","University of Liverpool Department of Chemistry The Robert Robinson Laboratories Liverpool UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Liverpool, Department of Chemistry, The Robert Robinson Laboratories, Liverpool, UK, L69 7ZD","institution_ids":["https://openalex.org/I146655781"]},{"raw_affiliation_string":"University of Liverpool Department of Chemistry The Robert Robinson Laboratories Liverpool UK","institution_ids":["https://openalex.org/I146655781"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5030009340"],"corresponding_institution_ids":["https://openalex.org/I146655781"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":5,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10091","display_name":"Malaria Research and Control","score":0.5557000041007996,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10091","display_name":"Malaria Research and Control","score":0.5557000041007996,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11547","display_name":"Sesquiterpenes and Asteraceae Studies","score":0.09809999912977219,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11747","display_name":"Metal-Catalyzed Oxygenation Mechanisms","score":0.07079999893903732,"subfield":{"id":"https://openalex.org/subfields/1604","display_name":"Inorganic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/endoperoxides","display_name":"endoperoxides","score":0.9259999990463257},{"id":"https://openalex.org/keywords/antimalarial-drugs","display_name":"antimalarial drugs","score":0.7770000100135803},{"id":"https://openalex.org/keywords/anticancer-agents","display_name":"anticancer agents","score":0.9520000219345093},{"id":"https://openalex.org/keywords/biomimetic-synthesis","display_name":"biomimetic synthesis","score":0.7919999957084656},{"id":"https://openalex.org/keywords/artemisinin-derivatives","display_name":"artemisinin derivatives","score":0.9710000157356262},{"id":"https://openalex.org/keywords/bioactivity","display_name":"biological activity","score":0.35100001096725464}],"concepts":[{"id":"https://openalex.org/C2776120307","wikidata":"https://www.wikidata.org/wiki/Q426921","display_name":"Artemisinin","level":4,"score":0.8710821866989136},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.795528769493103},{"id":"https://openalex.org/C21951064","wikidata":"https://www.wikidata.org/wiki/Q899212","display_name":"Combinatorial chemistry","level":1,"score":0.5461394190788269},{"id":"https://openalex.org/C2778371730","wikidata":"https://www.wikidata.org/wiki/Q311383","display_name":"Plasmodium falciparum","level":3,"score":0.46230024099349976},{"id":"https://openalex.org/C2778048844","wikidata":"https://www.wikidata.org/wiki/Q12156","display_name":"Malaria","level":2,"score":0.2751550078392029},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.06986802816390991},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1002/9780470682531.pat0363","doi":"https://doi.org/10.1002/9780470682531.pat0363","is_oa":false,"landing_page_url":"https://doi.org/10.1002/9780470682531.pat0363","pdf_url":null,"source":{"id":"https://openalex.org/S4210173804","display_name":"Patai's chemistry of functional groups","issn_l":"2042-5643","issn":["2042-5643","2042-5651"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PATAI'S Chemistry of Functional Groups","raw_type":"other"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.46810001134872437}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":156,"referenced_works":["https://openalex.org/W140864706","https://openalex.org/W1503809876","https://openalex.org/W1966004165","https://openalex.org/W1966866648","https://openalex.org/W1970327668","https://openalex.org/W1970370517","https://openalex.org/W1970980118","https://openalex.org/W1971229041","https://openalex.org/W1971874117","https://openalex.org/W1972419523","https://openalex.org/W1972596256","https://openalex.org/W1975741996","https://openalex.org/W1979439391","https://openalex.org/W1981147578","https://openalex.org/W1983041781","https://openalex.org/W1984525563","https://openalex.org/W1985210291","https://openalex.org/W1985372630","https://openalex.org/W1986200067","https://openalex.org/W1987213888","https://openalex.org/W1987576287","https://openalex.org/W1988588948","https://openalex.org/W1989272325","https://openalex.org/W1990245654","https://openalex.org/W1994671589","https://openalex.org/W1994951045","https://openalex.org/W1994957329","https://openalex.org/W1995685700","https://openalex.org/W1995829664","https://openalex.org/W1996340610","https://openalex.org/W2004990303","https://openalex.org/W2005898614","https://openalex.org/W2007060738","https://openalex.org/W2008241968","https://openalex.org/W2008246758","https://openalex.org/W2008759881","https://openalex.org/W2009012286","https://openalex.org/W2009200252","https://openalex.org/W2009793758","https://openalex.org/W2012421045","https://openalex.org/W2013090067","https://openalex.org/W2014387796","https://openalex.org/W2015244174","https://openalex.org/W2018979780","https://openalex.org/W2019647403","https://openalex.org/W2020560798","https://openalex.org/W2022163469","https://openalex.org/W2025547647","https://openalex.org/W2030428837","https://openalex.org/W2031646125","https://openalex.org/W2033721665","https://openalex.org/W2035131056","https://openalex.org/W2035183545","https://openalex.org/W2036394277","https://openalex.org/W2038553016","https://openalex.org/W2038910771","https://openalex.org/W2039223509","https://openalex.org/W2040694163","https://openalex.org/W2043048828","https://openalex.org/W2043645060","https://openalex.org/W2045334758","https://openalex.org/W2045615815","https://openalex.org/W2050506991","https://openalex.org/W2051527241","https://openalex.org/W2051544667","https://openalex.org/W2053727204","https://openalex.org/W2054247807","https://openalex.org/W2054288813","https://openalex.org/W2060937624","https://openalex.org/W2065179734","https://openalex.org/W2066645579","https://openalex.org/W2067051421","https://openalex.org/W2067629859","https://openalex.org/W2070339172","https://openalex.org/W2070457129","https://openalex.org/W2070828985","https://openalex.org/W2072246224","https://openalex.org/W2072856997","https://openalex.org/W2073246085","https://openalex.org/W2075346972","https://openalex.org/W2075373708","https://openalex.org/W2075522979","https://openalex.org/W2075750584","https://openalex.org/W2076384378","https://openalex.org/W2077188352","https://openalex.org/W2077980976","https://openalex.org/W2079456758","https://openalex.org/W2079682999","https://openalex.org/W2080892289","https://openalex.org/W2081374507","https://openalex.org/W2082187092","https://openalex.org/W2082266887","https://openalex.org/W2082601154","https://openalex.org/W2086845707","https://openalex.org/W2086952922","https://openalex.org/W2089288068","https://openalex.org/W2090870675","https://openalex.org/W2090895142","https://openalex.org/W2092370541","https://openalex.org/W2094716499","https://openalex.org/W2094912915","https://openalex.org/W2095186445","https://openalex.org/W2097652471","https://openalex.org/W2098184601","https://openalex.org/W2098683826","https://openalex.org/W2107214072","https://openalex.org/W2108523194","https://openalex.org/W2114840690","https://openalex.org/W2116580779","https://openalex.org/W2119899406","https://openalex.org/W2124634290","https://openalex.org/W2128371334","https://openalex.org/W2130860350","https://openalex.org/W2131661896","https://openalex.org/W2133374792","https://openalex.org/W2133603173","https://openalex.org/W2133990790","https://openalex.org/W2135804394","https://openalex.org/W2139878820","https://openalex.org/W2140124435","https://openalex.org/W2140543961","https://openalex.org/W2148219772","https://openalex.org/W2152183134","https://openalex.org/W2153177866","https://openalex.org/W2154357207","https://openalex.org/W2155885136","https://openalex.org/W2157746626","https://openalex.org/W2162079763","https://openalex.org/W2163501491","https://openalex.org/W2168360270","https://openalex.org/W2169938865","https://openalex.org/W2170408451","https://openalex.org/W2171440126","https://openalex.org/W2172195638","https://openalex.org/W2172596822","https://openalex.org/W2172767377","https://openalex.org/W2175198823","https://openalex.org/W2178553174","https://openalex.org/W2181657564","https://openalex.org/W2208706575","https://openalex.org/W2300598875","https://openalex.org/W2418515930","https://openalex.org/W2525415376","https://openalex.org/W2949649852","https://openalex.org/W2949934562","https://openalex.org/W2950131186","https://openalex.org/W2950181738","https://openalex.org/W2951199707","https://openalex.org/W2951719767","https://openalex.org/W2952293578","https://openalex.org/W2952760861","https://openalex.org/W2952882676","https://openalex.org/W2952992350","https://openalex.org/W4245250389","https://openalex.org/W4250817567","https://openalex.org/W4315563426"],"related_works":["https://openalex.org/W3192862420","https://openalex.org/W2130051189","https://openalex.org/W2118637056","https://openalex.org/W2951827875","https://openalex.org/W2020477416","https://openalex.org/W2181657564","https://openalex.org/W2949708978","https://openalex.org/W1992388085","https://openalex.org/W2018533686","https://openalex.org/W2169718709"],"abstract_inverted_index":{"Abstract":[0],"Introduction":[1],"Endoperoxide\u2010Containing":[2],"Antimalarials":[3,24],"The":[4,8],"Role":[5],"of":[6,11,21],"Iron":[7],"Biological":[9],"Targets":[10],"Antimalarial":[12,19],"Endoperoxides":[13,18],"Semi\u2010Synthetic":[14],"Artemisinin":[15],"Derivatives":[16],"Synthetic":[17,22],"Activities":[20],"Endoperoxide":[23,25],"Containing":[26],"Compounds":[27],"with":[28],"Antitumour":[29],"Activity":[30]},"counts_by_year":[{"year":2018,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-10-14T16:39:01.820549","created_date":"2016-06-24T00:00:00"}