{"id":"https://openalex.org/W2106877752","doi":null,"title":"PERIPARTUM CARDIOMYOPATHY - AN AUTOIMMUNE DISEASE?","display_name":"PERIPARTUM CARDIOMYOPATHY - AN AUTOIMMUNE DISEASE?","publication_year":2008,"publication_date":"2008-07-09","ids":{"openalex":"https://openalex.org/W2106877752","mag":"2106877752"},"language":"fi","primary_location":{"id":"pmh:oai:wiredspace.wits.ac.za:10539/5011","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10539/5011","pdf_url":"http://hdl.handle.net/10539/5011","source":{"id":"https://openalex.org/S4306400603","display_name":"University of the Witwatersrand, Johannesburg Institutional Repository on DSpace (University of the Witwatersrand, Johannesburg)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I192619145","host_organization_name":"University of the Witwatersrand","host_organization_lineage":["https://openalex.org/I192619145"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Thesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://hdl.handle.net/10539/5011","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5072441627","display_name":"Olaf F\u00f6rster","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Olaf F\u00f6rster","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5072441627"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":5,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12230","display_name":"Cardiovascular Issues in Pregnancy","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12230","display_name":"Cardiovascular Issues in Pregnancy","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12082","display_name":"Takotsubo Cardiomyopathy and Associated Phenomena","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11112","display_name":"Viral Infections and Immunology Research","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/peripartum-cardiomyopathy","display_name":"peripartum cardiomyopathy","score":0.9990000128746033},{"id":"https://openalex.org/keywords/autoimmune-hypothesis","display_name":"autoimmune hypothesis","score":0.7910000085830688},{"id":"https://openalex.org/keywords/fas-apo-1","display_name":"Fas/APO-1","score":0.765999972820282},{"id":"https://openalex.org/keywords/pro-inflammatory-cytokines","display_name":"inflammatory cytokines","score":0.796999990940094},{"id":"https://openalex.org/keywords/left-ventricular-ejection-fraction","display_name":"left ventricular ejection fraction","score":0.7739999890327454},{"id":"https://openalex.org/keywords/left-ventricular-remodeling","display_name":"left ventricular remodeling","score":0.6959999799728394},{"id":"https://openalex.org/keywords/prolactin","display_name":"prolactin","score":0.9210000038146973},{"id":"https://openalex.org/keywords/carvedilol","display_name":"carvedilol","score":0.7540000081062317},{"id":"https://openalex.org/keywords/ace-inhibitors","display_name":"ACE inhibitors","score":0.5820000171661377},{"id":"https://openalex.org/keywords/diuretics","display_name":"diuretics","score":0.6819999814033508},{"id":"https://openalex.org/keywords/risk-factors-for-mortality","display_name":"mortality risk factors","score":0.5320000052452087},{"id":"https://openalex.org/keywords/nyha-functional-class","display_name":"NYHA functional class","score":0.7170000076293945},{"id":"https://openalex.org/keywords/african-patients","display_name":"African patients","score":0.42899999022483826},{"id":"https://openalex.org/keywords/pathogenesis","display_name":"pathogenesis","score":0.4819999933242798},{"id":"https://openalex.org/keywords/prognosis","display_name":"prognosis","score":0.4779999852180481},{"id":"https://openalex.org/keywords/treatment-outcomes","display_name":"treatment outcomes","score":0.47600001096725464},{"id":"https://openalex.org/keywords/echocardiography","display_name":"echocardiography","score":0.5270000100135803}],"concepts":[{"id":"https://openalex.org/C2778490853","wikidata":"https://www.wikidata.org/wiki/Q2938089","display_name":"Peripartum cardiomyopathy","level":4,"score":0.9141025543212891},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5641920566558838},{"id":"https://openalex.org/C2778797674","wikidata":"https://www.wikidata.org/wiki/Q847583","display_name":"Cardiomyopathy","level":3,"score":0.5557260513305664},{"id":"https://openalex.org/C2779075594","wikidata":"https://www.wikidata.org/wiki/Q8084905","display_name":"Autoimmune disease","level":3,"score":0.5128922462463379},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.47484448552131653},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.3621768653392792},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3441534638404846},{"id":"https://openalex.org/C2778198053","wikidata":"https://www.wikidata.org/wiki/Q181754","display_name":"Heart failure","level":2,"score":0.14935800433158875}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:wiredspace.wits.ac.za:10539/5011","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10539/5011","pdf_url":"http://hdl.handle.net/10539/5011","source":{"id":"https://openalex.org/S4306400603","display_name":"University of the Witwatersrand, Johannesburg Institutional Repository on DSpace (University of the Witwatersrand, Johannesburg)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I192619145","host_organization_name":"University of the Witwatersrand","host_organization_lineage":["https://openalex.org/I192619145"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Thesis"},{"id":"mag:2106877752","doi":null,"is_oa":false,"landing_page_url":"https://wiredspace.wits.ac.za/bitstream/10539/5011/1/PhD%20Thesis%20final.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:wiredspace.wits.ac.za:10539/5011","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10539/5011","pdf_url":"http://hdl.handle.net/10539/5011","source":{"id":"https://openalex.org/S4306400603","display_name":"University of the Witwatersrand, Johannesburg Institutional Repository on DSpace (University of the Witwatersrand, Johannesburg)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I192619145","host_organization_name":"University of the Witwatersrand","host_organization_lineage":["https://openalex.org/I192619145"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Thesis"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2106877752.pdf","grobid_xml":"https://content.openalex.org/works/W2106877752.grobid-xml"},"referenced_works_count":285,"referenced_works":["https://openalex.org/W90205127","https://openalex.org/W104425974","https://openalex.org/W137510100","https://openalex.org/W143607315","https://openalex.org/W197144613","https://openalex.org/W199042638","https://openalex.org/W1033997842","https://openalex.org/W1504326672","https://openalex.org/W1523893866","https://openalex.org/W1536727395","https://openalex.org/W1537173083","https://openalex.org/W1543098232","https://openalex.org/W1546282296","https://openalex.org/W1549631663","https://openalex.org/W1554696140","https://openalex.org/W1570888300","https://openalex.org/W1580440762","https://openalex.org/W1583233550","https://openalex.org/W1651870498","https://openalex.org/W1716116231","https://openalex.org/W1765860681","https://openalex.org/W1835992833","https://openalex.org/W1839417550","https://openalex.org/W1875039943","https://openalex.org/W1889478346","https://openalex.org/W1942737913","https://openalex.org/W1965229834","https://openalex.org/W1965346652","https://openalex.org/W1965575731","https://openalex.org/W1965881193","https://openalex.org/W1966957841","https://openalex.org/W1967128858","https://openalex.org/W1967826895","https://openalex.org/W1969017761","https://openalex.org/W1970474122","https://openalex.org/W1971340914","https://openalex.org/W1972209585","https://openalex.org/W1973192479","https://openalex.org/W1974643351","https://openalex.org/W1974718574","https://openalex.org/W1975086901","https://openalex.org/W1976605490","https://openalex.org/W1977720615","https://openalex.org/W1978018492","https://openalex.org/W1978628324","https://openalex.org/W1979420668","https://openalex.org/W1980486708","https://openalex.org/W1981027292","https://openalex.org/W1981785818","https://openalex.org/W1983166456","https://openalex.org/W1983223570","https://openalex.org/W1984915036","https://openalex.org/W1985072137","https://openalex.org/W1985166433","https://openalex.org/W1985429918","https://openalex.org/W1986638254","https://openalex.org/W1987226971","https://openalex.org/W1988555532","https://openalex.org/W1988773159","https://openalex.org/W1991115595","https://openalex.org/W1992060545","https://openalex.org/W1992477495","https://openalex.org/W1992742904","https://openalex.org/W1994426704","https://openalex.org/W1994549439","https://openalex.org/W1995997868","https://openalex.org/W1996479248","https://openalex.org/W1997311041","https://openalex.org/W1997462209","https://openalex.org/W1998031269","https://openalex.org/W1998486839","https://openalex.org/W2000107356","https://openalex.org/W2000862529","https://openalex.org/W2000911441","https://openalex.org/W2001926769","https://openalex.org/W2002991079","https://openalex.org/W2003148209","https://openalex.org/W2003652884","https://openalex.org/W2003721105","https://openalex.org/W2004445097","https://openalex.org/W2004561538","https://openalex.org/W2004666693","https://openalex.org/W2005060225","https://openalex.org/W2005497837","https://openalex.org/W2006431355","https://openalex.org/W2007209818","https://openalex.org/W2007843799","https://openalex.org/W2009202939","https://openalex.org/W2012299887","https://openalex.org/W2012711566","https://openalex.org/W2013272468","https://openalex.org/W2015260577","https://openalex.org/W2015708271","https://openalex.org/W2015844170","https://openalex.org/W2016646689","https://openalex.org/W2019712429","https://openalex.org/W2020135856","https://openalex.org/W2020451618","https://openalex.org/W2021680265","https://openalex.org/W2023391583","https://openalex.org/W2023582771","https://openalex.org/W2024456541","https://openalex.org/W2026706036","https://openalex.org/W2027068762","https://openalex.org/W2027540929","https://openalex.org/W2028741040","https://openalex.org/W2029654767","https://openalex.org/W2031037863","https://openalex.org/W2031247901","https://openalex.org/W2032198859","https://openalex.org/W2032413810","https://openalex.org/W2032511198","https://openalex.org/W2033288293","https://openalex.org/W2034163879","https://openalex.org/W2034211901","https://openalex.org/W2034925125","https://openalex.org/W2035756092","https://openalex.org/W2037218561","https://openalex.org/W2038114873","https://openalex.org/W2038412204","https://openalex.org/W2038794532","https://openalex.org/W2039612376","https://openalex.org/W2041729900","https://openalex.org/W2043374524","https://openalex.org/W2046123379","https://openalex.org/W2046275929","https://openalex.org/W2046494837","https://openalex.org/W2048711081","https://openalex.org/W2048748125","https://openalex.org/W2049348368","https://openalex.org/W2050649115","https://openalex.org/W2051233933","https://openalex.org/W2051636000","https://openalex.org/W2053021150","https://openalex.org/W2053848519","https://openalex.org/W2055590153","https://openalex.org/W2057625875","https://openalex.org/W2058561523","https://openalex.org/W2059086489","https://openalex.org/W2060171803","https://openalex.org/W2061952905","https://openalex.org/W2063311461","https://openalex.org/W2063379753","https://openalex.org/W2063774663","https://openalex.org/W2065447230","https://openalex.org/W2065601509","https://openalex.org/W2065724905","https://openalex.org/W2065769644","https://openalex.org/W2066605855","https://openalex.org/W2068742355","https://openalex.org/W2068785830","https://openalex.org/W2068888013","https://openalex.org/W2069485793","https://openalex.org/W2070446231","https://openalex.org/W2070578868","https://openalex.org/W2070821163","https://openalex.org/W2071485583","https://openalex.org/W2075417545","https://openalex.org/W2075820472","https://openalex.org/W2076815041","https://openalex.org/W2078014987","https://openalex.org/W2078055222","https://openalex.org/W2079217588","https://openalex.org/W2079892115","https://openalex.org/W2080856124","https://openalex.org/W2082163559","https://openalex.org/W2082692470","https://openalex.org/W2083376390","https://openalex.org/W2084475107","https://openalex.org/W2084685244","https://openalex.org/W2085758985","https://openalex.org/W2086177904","https://openalex.org/W2086194897","https://openalex.org/W2087522976","https://openalex.org/W2087695885","https://openalex.org/W2087714532","https://openalex.org/W2088749722","https://openalex.org/W2089343531","https://openalex.org/W2090375690","https://openalex.org/W2091287469","https://openalex.org/W2091429277","https://openalex.org/W2093131177","https://openalex.org/W2093706823","https://openalex.org/W2093852655","https://openalex.org/W2093900936","https://openalex.org/W2093958208","https://openalex.org/W2095050384","https://openalex.org/W2095106505","https://openalex.org/W2096073058","https://openalex.org/W2097841516","https://openalex.org/W2098656972","https://openalex.org/W2098812736","https://openalex.org/W2099084751","https://openalex.org/W2100390013","https://openalex.org/W2102959694","https://openalex.org/W2103042940","https://openalex.org/W2103529976","https://openalex.org/W2107548301","https://openalex.org/W2108420416","https://openalex.org/W2110760761","https://openalex.org/W2111630252","https://openalex.org/W2113162775","https://openalex.org/W2114076717","https://openalex.org/W2115635074","https://openalex.org/W2116267505","https://openalex.org/W2118161860","https://openalex.org/W2119299191","https://openalex.org/W2122095615","https://openalex.org/W2123939166","https://openalex.org/W2124312719","https://openalex.org/W2126834790","https://openalex.org/W2130207729","https://openalex.org/W2130727497","https://openalex.org/W2131687335","https://openalex.org/W2135456817","https://openalex.org/W2136094484","https://openalex.org/W2137412139","https://openalex.org/W2138018919","https://openalex.org/W2139367661","https://openalex.org/W2141971127","https://openalex.org/W2143634855","https://openalex.org/W2145450205","https://openalex.org/W2146361868","https://openalex.org/W2146429955","https://openalex.org/W2146902372","https://openalex.org/W2147145830","https://openalex.org/W2148001793","https://openalex.org/W2150184024","https://openalex.org/W2151911209","https://openalex.org/W2152325558","https://openalex.org/W2152658552","https://openalex.org/W2152907499","https://openalex.org/W2153104756","https://openalex.org/W2153263323","https://openalex.org/W2153704552","https://openalex.org/W2156116460","https://openalex.org/W2156275638","https://openalex.org/W2156720518","https://openalex.org/W2157332614","https://openalex.org/W2158439676","https://openalex.org/W2158716848","https://openalex.org/W2159513257","https://openalex.org/W2161501502","https://openalex.org/W2166377192","https://openalex.org/W2167141086","https://openalex.org/W2167259218","https://openalex.org/W2167504169","https://openalex.org/W2169059936","https://openalex.org/W2169410058","https://openalex.org/W2169835977","https://openalex.org/W2170192667","https://openalex.org/W2172111517","https://openalex.org/W2172466148","https://openalex.org/W2186852052","https://openalex.org/W2216806740","https://openalex.org/W2229802783","https://openalex.org/W2240064990","https://openalex.org/W2319459971","https://openalex.org/W2320264340","https://openalex.org/W2324841714","https://openalex.org/W2361880524","https://openalex.org/W2362891015","https://openalex.org/W2398924956","https://openalex.org/W2401802475","https://openalex.org/W2404828974","https://openalex.org/W2405420978","https://openalex.org/W2409572372","https://openalex.org/W2410676200","https://openalex.org/W2411709627","https://openalex.org/W2412197530","https://openalex.org/W2413089723","https://openalex.org/W2413248475","https://openalex.org/W2413482117","https://openalex.org/W2413502482","https://openalex.org/W2413717828","https://openalex.org/W2414008377","https://openalex.org/W2414837252","https://openalex.org/W2415002250","https://openalex.org/W2419835186","https://openalex.org/W2420839279","https://openalex.org/W2461799632","https://openalex.org/W2464479696","https://openalex.org/W2471241722","https://openalex.org/W2473119043","https://openalex.org/W3142596652"],"related_works":["https://openalex.org/W1983219569","https://openalex.org/W1491519846","https://openalex.org/W2068742355","https://openalex.org/W1965559802","https://openalex.org/W2911641611","https://openalex.org/W243677591","https://openalex.org/W2324489689","https://openalex.org/W4234552221","https://openalex.org/W2313406197","https://openalex.org/W4242152072"],"abstract_inverted_index":{"ABSTRACT":[0],"\\nIntroduction:":[1],"Peripartum":[2],"cardiomyopathy":[3],"(PPCM)":[4],"is":[5,49],"defined":[6],"as":[7,542,544,778],"a":[8,124,136,225,394,400,450,454,475,512,549,635,807,859],"disorder":[9],"of":[10,32,78,83,92,98,105,112,131,141,183,190,200,222,228,258,267,273,295,330,354,359,367,375,406,414,417,445,461,467,472,495,516,521,535,552,569,662,678,686,723,732,754,770,797,820,864,871,903],"unknown":[11],"aetiology":[12],"that":[13,349,391,739,816,836],"\\noccurs":[14],"between":[15,37,70,403,587,638],"one":[16,813],"month":[17],"antepartum":[18],"and":[19,40,72,114,122,166,175,187,203,234,239,282,299,313,318,333,380,410,518,539,557,591,615,625,641,692,746,822,850,875,890],"five":[20],"months":[21,189,202,221,425],"postpartum":[22],"in":[23,44,103,116,128,237,264,325,352,365,373,386,443,453,478,483,499,506,563,575,601,623,657,666,711,715,720,743,799,806,830,847,861,868,888],"women":[24],"without":[25],"pre-existing":[26],"heart":[27,229,503,528,803],"\\ndisease.":[28],"While":[29],"the":[30,45,52,89,129,161,197,268,310,331,343,360,404,407,415,436,465,468,493,496,576,579,619,639,670,674,684,693,721,736,768,795,827,862,900],"incidence":[31,57],"PPCM":[33,94,326,355,368,377,392,446,455,479,508,565,658,712,744,771,904],"has":[34,833],"been":[35,834],"reported":[36],"1:":[38,60,63],"2392":[39],"15000":[41],"live":[42],"births":[43],"USA,":[46],"\\nthe":[47,785],"disease":[48,396,602,725,846],"ubiquitous":[50],"on":[51,309,526],"African":[53],"continent":[54],"with":[55,157,388,511,735,893],"an":[56,609,616,758],"ranging":[58],"from":[59,303,338,421],"100":[61,93,142],"to":[62,76,87,214,307,342,423,433,501,524,618,627,701,730,750,762,773,781,793,801,882],"1000":[64],"\\ndeliveries.":[65],"The":[66,320,362],"mortality":[67],"rate":[68],"ranges":[69],"15":[71],"40.7%,":[73],"while":[74,301,336],"23":[75],"54%":[77],"patients":[79,145,152,194,305,327,356,369,387,523,566,659,745,756,892],"recover":[80],"completely.":[81],"\\nAim":[82],"this":[84],"thesis":[85],"was":[86,261,717,787],"describe":[88],"clinical":[90,490,517,810],"profile":[91],"patients,":[95,447,480,509],"identify":[96],"predictors":[97,294],"negative":[99],"\\noutcome,":[100],"analyze":[101],"differences":[102,584],"kinetics":[104],"cardiac":[106,117,418,555,588,620,763],"function":[107,118,419,541,589],"biomarkers,":[108],"pro-inflammatory":[109,558,707],"cytokines,":[110],"\\nmarkers":[111],"re-modeling":[113],"prolactin":[115,440,473,655,817,839,854,884],"improvers":[119,590],"versus":[120],"non-improvers":[121],"investigate":[123,794],"\\npossible":[125],"autoimmune":[126,613,695,724,845],"component":[127],"pathogenesis":[130,769,863,902],"PPCM.":[132,150,679],"\\nMethods:":[133],"We":[134,398],"conducted":[135],"single":[137],"centre,":[138],"prospective":[139],"study":[140,883],"newly":[143],"diagnosed":[144],"meeting":[146],"\\ndiagnostic":[147],"criteria":[148],"for":[149,208,243,438],"All":[151],"received":[153],"standard":[154,502,802],"anti-failure":[155],"therapy":[156,505,530,805],"diuretics":[158],"(furosemide,":[159],"\\naldactone),":[160],"\u03b2-blocker":[162],"carvedilol,":[163],"ACE-inhibitor":[164],"perindopril":[165],"digoxin":[167],"if":[168],"indicated.":[169,906],"Clinical":[170],"assessment,":[171],"\\n2-dimensional":[172],"echocardiographic":[173,519],"studies":[174,898],"blood":[176],"analysis":[177],"were":[178,205,292,370],"systematically":[179],"performed":[180],"at":[181,567,660],"time":[182,568,586,661],"\\npresentation,":[184],"after":[185],"six":[186,201,220],"twelve":[188,424],"therapy.":[191],"\\nFindings:":[192],"Fifteen":[193],"died":[195],"within":[196],"follow-up":[198,210],"period":[199],"eight":[204],"not":[206,371,482,856],"available":[207],"\\nfull":[209],"since":[211],"they":[212],"moved":[213],"remote":[215],"areas.":[216],"Patients":[217],"who":[218],"completed":[219],"treatment":[223],"showed":[224],"\\nsignificant":[226],"reduction":[227],"rate,":[230],"left":[231,244,536,629],"ventricular":[232,245,537,630],"dimensions":[233,538],"significant":[235,583],"improvement":[236,534],"\\nscintigraphically":[238],"echocardiographically":[240],"derived":[241],"values":[242],"ejection":[246],"fraction":[247],"(p<":[248,254],"0.0001)":[249],"\\nand":[250,726],"NYHA":[251,283,545],"functional":[252],"class":[253],"0.001).":[255],"However,":[256],"normalization":[257],"LVEF":[259],"(>50%)":[260],"only":[262,857],"observed":[263],"18":[265],"\\n(23%)":[266],"patients.":[269],"Baseline":[270],"plasma":[271],"levels":[272,413,442,460,887],"Fas/Apo-1":[274],"(OR":[275],"=":[276,280,286,290],"3.56,":[277],"CI":[278,288,431],"95%":[279,289,430],"1.35\u20139.42)":[281],"FC":[284],"\\n(OR":[285],"2.67,":[287],"1.04\u20136.83)":[291],"independent":[293],"death.extra-cellular":[296],"loop":[297,316],"(RAESDE":[298],"DEARRCY),":[300],"those":[302,337,384],"DCMO":[304,339],"bind":[306],"epitopes":[308],"\\nfirst":[311],"(30%)":[312],"second":[314],"extra-cellular":[315],"(ARRCYND":[317],"PKCCDF).":[319],"\u03b21-adrenoreceptor":[321,350,363,408,737],"agonist-like":[322],"\\nantibodies":[323],"identified":[324,449,742],"are":[328,381,841,905],"part":[329],"IgG2":[332,344],"IgG3":[334],"subclass,":[335],"\\npatients":[340],"belong":[341],"subclass.":[345],"Furthermore":[346],"we":[347,448,581,649,740],"demonstrated":[348,531,748],"antibodies":[351,364,409],"\\nserum":[353,366],"prevented":[357],"desensitization":[358,731],"receptor.":[361],"detectable":[372],"serum":[374,411,444,596,654,838,885],"non":[376],"peripartum":[378,667],"controls":[379],"different":[382],"\\nfrom":[383],"found":[385,582,650],"DCMO,":[389],"suggesting":[390,598,669],"forms":[393,870],"distinct":[395],"entity.":[397],"\\ndemonstrated":[399],"positive":[401],"correlation":[402],"activity":[405],"\\nexpression":[412],"marker":[416],"NT-proBNP":[420],"baseline":[422],"(rs=0.58,":[426],"2-":[427],"\\ntailed":[428],"P=0.0228),":[429],"(0.10":[432],"0.84).":[434],"\\nInvestigating":[435],"cause":[437,464],"high":[439,710],"expression":[441,606,819,886],"\\nSTAT3":[451],"deficit":[452],"mouse":[456],"model.":[457],"Significantly":[458],"increased":[459],"cathepsin":[462],"D":[463],"cleavage":[466],"physiological":[469],"23-kDa":[470],"form":[471,477],"into":[474,899],"16-kDa":[476],"but":[481,866],"non-PPCM":[484],"\\nperipartum":[485],"controls.":[486],"This":[487,706],"initiated":[488],"another":[489],"study,":[491],"investigating":[492],"effect":[494],"prolactin-inhibitor":[497],"\\nbromocriptine":[498],"addition":[500],"failure":[504,529,804],"known":[507],"presenting":[510],"\\nsubsequent":[513],"pregnancy.":[514],"Comparison":[515],"data":[520],"these":[522],"others":[525],"\\nstandard":[527],"preservation":[532],"or":[533],"\\nsystolic":[540],"well":[543],"FC.":[546],"\\nConclusion:":[547],"\\nWhile":[548,767],"wide":[550],"range":[551],"parameters,":[553],"reflecting":[554],"dysfunction":[556],"immune":[559,642],"activation,":[560],"\\nwere":[561],"elevated":[562,837],"all":[564],"first":[570,663],"presentation,":[571],"indicating":[572],"their":[573,599,747],"involvement":[574],"initiation":[577],"\\nof":[578],"disease,":[580],"over":[585],"nonimprovers":[592],"\\nfor":[593],"\u0394IFN-gamma":[594],"(P=0.0181)":[595],"levels,":[597],"role":[600],"progression.":[603],"\\nHeightened":[604],"IFN-gamma":[605,687,821],"could":[607,814],"indicate":[608],"ongoing":[610,694],"T-cell":[611],"mediated":[612],"response":[614],"\\ninsult":[617],"muscle,":[621],"resulting":[622],"fibrosis":[624],"inability":[626],"improve":[628],"systolic":[631],"function.":[632],"\\nProlactin":[633],"represents":[634],"stimulatory":[636],"link":[637],"neuroendocrine":[640],"systems,":[643],"promoting":[644],"proinflammatory":[645],"\\nimmune":[646],"responses.":[647],"Interestingly,":[648],"significantly":[651],"higher":[652],"(P<0.0001)":[653],"\\nlevels":[656],"presentation":[664],"than":[665],"controls,":[668],"hormone\u2019s":[671],"\\nrole":[672,860],"during":[673],"initial":[675],"acute":[676],"phase":[677],"Several":[680],"authors":[681],"have":[682,741],"described":[683],"induction":[685],"by":[688,697,704],"\\nprolactin.":[689],"Disease":[690],"progression":[691],"insult":[696],"beta1-adrenergic":[698],"autoantibodies":[699],"\\nappear":[700],"be":[702,774,880],"driven":[703],"IFN-gamma.":[705],"cytokine":[708],"remained":[709],"nonimprovers,":[713],"\\ndecreased":[714],"improvers,":[716],"previously":[718],"implicated":[719],"development":[722],"its":[727],"suppression":[728],"leads":[729],"\u03b2-adrenoreceptors.":[733],"Together":[734],"\\nautoantibodies":[738],"property":[749],"also":[751,867],"prevent":[752],"\\ndesensitization":[753],"\u03b21-adrenoreceptors,":[755],"experience":[757],"adrenergic":[759],"overdrive,":[760],"leading":[761],"\\nmyocyte":[764],"insult.":[765],"\\n10":[766],"appears":[772,791],"multifactorial,":[775],"our":[776],"task":[777],"scientists":[779],"remains":[780],"find":[782],"out,":[783],"how":[784],"monolith":[786],"erected.":[788],"Specifically,":[789],"it":[790,832],"promising":[792],"effects":[796],"bromocriptine":[798],"\\naddition":[800],"randomised,":[808],"double-blinded":[809],"study.":[811],"Although":[812],"\\nargue":[815],"regulated":[818],"other":[823,869],"cytokines":[824],"may":[825],"explain":[826],"gender-specific":[828],"\\ndifferences":[829],"autoimmunity,":[831],"shown":[835],"concentrations":[840],"associated":[842],"\\nwith":[843],"accelerated":[844],"both":[848],"female":[849,891],"male":[851,889],"mice.":[852],"Possibly,":[853],"does":[855],"play":[858],"PPCM,":[865],"cardiomyopathy,":[872],"affecting":[873],"males":[874],"females":[876],"\\nalike.":[877],"It":[878],"would":[879],"interesting":[881],"\\nidiopathic":[894],"DCMO.":[895],"Clearly,":[896],"further":[897],"unfolding":[901]},"counts_by_year":[{"year":2017,"cited_by_count":2},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}
