{"id":"https://openalex.org/W2106434503","doi":"https://doi.org/10.1128/aem.01058-07","title":"N-Glycan Modification in Aspergillus Species","display_name":"N-Glycan Modification in Aspergillus Species","publication_year":2007,"publication_date":"2007-12-15","ids":{"openalex":"https://openalex.org/W2106434503","doi":"https://doi.org/10.1128/aem.01058-07","mag":"2106434503","pmid":"https://pubmed.ncbi.nlm.nih.gov/18083888","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2258586"},"language":"en","primary_location":{"id":"doi:10.1128/aem.01058-07","doi":"https://doi.org/10.1128/aem.01058-07","is_oa":false,"landing_page_url":"https://doi.org/10.1128/aem.01058-07","pdf_url":null,"source":{"id":"https://openalex.org/S158228368","display_name":"Applied and Environmental Microbiology","issn_l":"0099-2240","issn":["0099-2240","1070-6291","1098-5336"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Applied and Environmental Microbiology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2258586","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5051253276","display_name":"Elke Kainz","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I132118926","display_name":"AIT Austrian Institute of Technology GmbH","ror":"https://ror.org/04knbh022","country_code":"AT","type":"facility","lineage":["https://openalex.org/I132118926"]},{"id":"https://openalex.org/I92869138","display_name":"BOKU University","ror":"https://ror.org/057ff4y42","country_code":"AT","type":"education","lineage":["https://openalex.org/I92869138"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Elke Kainz","raw_affiliation_strings":["Fungal Genomics Unit, Austrian Research Centers and BOKU Vienna, Muthgasse 18, A-1190 Vienna, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Fungal Genomics Unit, Austrian Research Centers and BOKU Vienna, Muthgasse 18, A-1190 Vienna, Austria","institution_ids":["https://openalex.org/I132118926","https://openalex.org/I92869138"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081564443","display_name":"Andreas Gallmetzer","orcid":"https://orcid.org/0000-0002-9416-2080","observed_orcids":["https://orcid.org/0000-0002-9416-2080"]},"institutions":[{"id":"https://openalex.org/I132118926","display_name":"AIT Austrian Institute of Technology GmbH","ror":"https://ror.org/04knbh022","country_code":"AT","type":"facility","lineage":["https://openalex.org/I132118926"]},{"id":"https://openalex.org/I92869138","display_name":"BOKU University","ror":"https://ror.org/057ff4y42","country_code":"AT","type":"education","lineage":["https://openalex.org/I92869138"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Andreas Gallmetzer","raw_affiliation_strings":["Fungal Genomics Unit, Austrian Research Centers and BOKU Vienna, Muthgasse 18, A-1190 Vienna, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Fungal Genomics Unit, Austrian Research Centers and BOKU Vienna, Muthgasse 18, A-1190 Vienna, Austria","institution_ids":["https://openalex.org/I132118926","https://openalex.org/I92869138"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035667534","display_name":"Christian Hatzl","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I132118926","display_name":"AIT Austrian Institute of Technology GmbH","ror":"https://ror.org/04knbh022","country_code":"AT","type":"facility","lineage":["https://openalex.org/I132118926"]},{"id":"https://openalex.org/I92869138","display_name":"BOKU University","ror":"https://ror.org/057ff4y42","country_code":"AT","type":"education","lineage":["https://openalex.org/I92869138"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Christian Hatzl","raw_affiliation_strings":["Fungal Genomics Unit, Austrian Research Centers and BOKU Vienna, Muthgasse 18, A-1190 Vienna, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Fungal Genomics Unit, Austrian Research Centers and BOKU Vienna, Muthgasse 18, A-1190 Vienna, Austria","institution_ids":["https://openalex.org/I132118926","https://openalex.org/I92869138"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053763145","display_name":"Juergen H. Nett","orcid":"https://orcid.org/0000-0002-1410-683X","observed_orcids":["https://orcid.org/0000-0002-1410-683X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Juergen H. Nett","raw_affiliation_strings":["GlycoFi, Inc., 21 Lafayette Street, Lebanon, New Hampshire 03766"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"GlycoFi, Inc., 21 Lafayette Street, Lebanon, New Hampshire 03766","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109968138","display_name":"Huijuan Li","orcid":"https://orcid.org/0000-0003-4789-2926","observed_orcids":["https://orcid.org/0000-0003-4789-2926","https://orcid.org/0009-0008-4500-7341","https://orcid.org/0009-0009-8875-8994"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Huijuan Li","raw_affiliation_strings":["GlycoFi, Inc., 21 Lafayette Street, Lebanon, New Hampshire 03766"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"GlycoFi, Inc., 21 Lafayette Street, Lebanon, New Hampshire 03766","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066627641","display_name":"Thorsten Schinko","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I132118926","display_name":"AIT Austrian Institute of Technology GmbH","ror":"https://ror.org/04knbh022","country_code":"AT","type":"facility","lineage":["https://openalex.org/I132118926"]},{"id":"https://openalex.org/I92869138","display_name":"BOKU University","ror":"https://ror.org/057ff4y42","country_code":"AT","type":"education","lineage":["https://openalex.org/I92869138"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Thorsten Schinko","raw_affiliation_strings":["Fungal Genomics Unit, Austrian Research Centers and BOKU Vienna, Muthgasse 18, A-1190 Vienna, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Fungal Genomics Unit, Austrian Research Centers and BOKU Vienna, Muthgasse 18, A-1190 Vienna, Austria","institution_ids":["https://openalex.org/I132118926","https://openalex.org/I92869138"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020842238","display_name":"Robert Pachlinger","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I132118926","display_name":"AIT Austrian Institute of Technology GmbH","ror":"https://ror.org/04knbh022","country_code":"AT","type":"facility","lineage":["https://openalex.org/I132118926"]},{"id":"https://openalex.org/I92869138","display_name":"BOKU University","ror":"https://ror.org/057ff4y42","country_code":"AT","type":"education","lineage":["https://openalex.org/I92869138"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Robert Pachlinger","raw_affiliation_strings":["Fungal Genomics Unit, Austrian Research Centers and BOKU Vienna, Muthgasse 18, A-1190 Vienna, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Fungal Genomics Unit, Austrian Research Centers and BOKU Vienna, Muthgasse 18, A-1190 Vienna, Austria","institution_ids":["https://openalex.org/I132118926","https://openalex.org/I92869138"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103274544","display_name":"Harald Berger","orcid":"https://orcid.org/0000-0002-0413-7763","observed_orcids":["https://orcid.org/0000-0002-0413-7763"]},"institutions":[{"id":"https://openalex.org/I132118926","display_name":"AIT Austrian Institute of Technology GmbH","ror":"https://ror.org/04knbh022","country_code":"AT","type":"facility","lineage":["https://openalex.org/I132118926"]},{"id":"https://openalex.org/I92869138","display_name":"BOKU University","ror":"https://ror.org/057ff4y42","country_code":"AT","type":"education","lineage":["https://openalex.org/I92869138"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Harald Berger","raw_affiliation_strings":["Fungal Genomics Unit, Austrian Research Centers and BOKU Vienna, Muthgasse 18, A-1190 Vienna, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Fungal Genomics Unit, Austrian Research Centers and BOKU Vienna, Muthgasse 18, A-1190 Vienna, Austria","institution_ids":["https://openalex.org/I132118926","https://openalex.org/I92869138"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044858728","display_name":"Yazmid Reyes-Dom\u00ednguez","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I132118926","display_name":"AIT Austrian Institute of Technology GmbH","ror":"https://ror.org/04knbh022","country_code":"AT","type":"facility","lineage":["https://openalex.org/I132118926"]},{"id":"https://openalex.org/I92869138","display_name":"BOKU University","ror":"https://ror.org/057ff4y42","country_code":"AT","type":"education","lineage":["https://openalex.org/I92869138"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Yazmid Reyes-Dominguez","raw_affiliation_strings":["Fungal Genomics Unit, Austrian Research Centers and BOKU Vienna, Muthgasse 18, A-1190 Vienna, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Fungal Genomics Unit, Austrian Research Centers and BOKU Vienna, Muthgasse 18, A-1190 Vienna, Austria","institution_ids":["https://openalex.org/I132118926","https://openalex.org/I92869138"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040993791","display_name":"Andreas Bernreiter","orcid":"https://orcid.org/0000-0001-8233-5274","observed_orcids":["https://orcid.org/0000-0001-8233-5274"]},"institutions":[{"id":"https://openalex.org/I132118926","display_name":"AIT Austrian Institute of Technology GmbH","ror":"https://ror.org/04knbh022","country_code":"AT","type":"facility","lineage":["https://openalex.org/I132118926"]},{"id":"https://openalex.org/I92869138","display_name":"BOKU University","ror":"https://ror.org/057ff4y42","country_code":"AT","type":"education","lineage":["https://openalex.org/I92869138"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Andreas Bernreiter","raw_affiliation_strings":["Fungal Genomics Unit, Austrian Research Centers and BOKU Vienna, Muthgasse 18, A-1190 Vienna, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Fungal Genomics Unit, Austrian Research Centers and BOKU Vienna, Muthgasse 18, A-1190 Vienna, Austria","institution_ids":["https://openalex.org/I132118926","https://openalex.org/I92869138"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073447905","display_name":"Tillman U. Gerngross","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I107672454","display_name":"Dartmouth College","ror":"https://ror.org/049s0rh22","country_code":"US","type":"education","lineage":["https://openalex.org/I107672454"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tillmann Gerngross","raw_affiliation_strings":["GlycoFi, Inc., 21 Lafayette Street, Lebanon, New Hampshire 03766","Thayer School of Engineering, Dartmouth College, 8000 Cummings Hall, Hanover, New Hampshire 03755"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"GlycoFi, Inc., 21 Lafayette Street, Lebanon, New Hampshire 03766","institution_ids":[]},{"raw_affiliation_string":"Thayer School of Engineering, Dartmouth College, 8000 Cummings Hall, Hanover, New Hampshire 03755","institution_ids":["https://openalex.org/I107672454"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030674338","display_name":"Stefan Wildt","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Stefan Wildt","raw_affiliation_strings":["GlycoFi, Inc., 21 Lafayette Street, Lebanon, New Hampshire 03766"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"GlycoFi, Inc., 21 Lafayette Street, Lebanon, New Hampshire 03766","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5023933418","display_name":"Joseph Strauss","orcid":"https://orcid.org/0000-0003-0474-6267","observed_orcids":["https://orcid.org/0000-0003-0474-6267"]},"institutions":[{"id":"https://openalex.org/I132118926","display_name":"AIT Austrian Institute of Technology GmbH","ror":"https://ror.org/04knbh022","country_code":"AT","type":"facility","lineage":["https://openalex.org/I132118926"]},{"id":"https://openalex.org/I92869138","display_name":"BOKU University","ror":"https://ror.org/057ff4y42","country_code":"AT","type":"education","lineage":["https://openalex.org/I92869138"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Joseph Strauss","raw_affiliation_strings":["Fungal Genomics Unit, Austrian Research Centers and BOKU Vienna, Muthgasse 18, A-1190 Vienna, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Fungal Genomics Unit, Austrian Research Centers and BOKU Vienna, Muthgasse 18, A-1190 Vienna, Austria","institution_ids":["https://openalex.org/I132118926","https://openalex.org/I92869138"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.0877,"has_fulltext":false,"cited_by_count":58,"citation_normalized_percentile":{"value":0.72340852,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"74","issue":"4","first_page":"1076","last_page":"1086"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10497","display_name":"Fungal and yeast genetics research","score":0.7113999724388123,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10497","display_name":"Fungal and yeast genetics research","score":0.7113999724388123,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10602","display_name":"Glycosylation and Glycoproteins Research","score":0.26440000534057617,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11663","display_name":"Viral Infectious Diseases and Gene Expression in Insects","score":0.019300000742077827,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/aspergillus","display_name":"Aspergillus","score":0.9890000224113464},{"id":"https://openalex.org/keywords/fungal-glycosylation","display_name":"fungal glycosylation","score":0.7630000114440918},{"id":"https://openalex.org/keywords/heterologous-expression","display_name":"heterologous expression","score":0.7009999752044678},{"id":"https://openalex.org/keywords/alpha-1-2-mannosidase","display_name":"alpha-1,2-mannosidase","score":0.8999999761581421},{"id":"https://openalex.org/keywords/man5glcnac2","display_name":"Man5GlcNAc2","score":0.8320000171661377},{"id":"https://openalex.org/keywords/therapeutic-glycoproteins","display_name":"therapeutic glycoproteins","score":0.746999979019165},{"id":"https://openalex.org/keywords/chimeric-fusion-protein","display_name":"chimeric fusion protein","score":0.8009999990463257},{"id":"https://openalex.org/keywords/glycosylation-pathway","display_name":"glycosylation pathway","score":0.5460000038146973}],"concepts":[{"id":"https://openalex.org/C206212055","wikidata":"https://www.wikidata.org/wiki/Q2553138","display_name":"Glycan","level":3,"score":0.7814819812774658},{"id":"https://openalex.org/C2779175654","wikidata":"https://www.wikidata.org/wiki/Q335130","display_name":"Aspergillus","level":2,"score":0.6250401139259338},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.465705931186676},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.46437326073646545},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.43311935663223267},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3698723614215851},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.2796398401260376},{"id":"https://openalex.org/C108625454","wikidata":"https://www.wikidata.org/wiki/Q187126","display_name":"Glycoprotein","level":2,"score":0.0924929678440094}],"mesh":[{"descriptor_ui":"D001230","descriptor_name":"Aspergillus","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003001","descriptor_name":"Cloning, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008364","descriptor_name":"Mannosyltransferases","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011134","descriptor_name":"Polysaccharides","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":true},{"descriptor_ui":"D011134","descriptor_name":"Polysaccharides","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D011993","descriptor_name":"Recombinant Fusion Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014169","descriptor_name":"Transformation, Bacterial","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D015202","descriptor_name":"Protein Engineering","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D017422","descriptor_name":"Sequence Analysis, DNA","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017931","descriptor_name":"DNA Primers","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D018014","descriptor_name":"Gene Transfer Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019032","descriptor_name":"Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020133","descriptor_name":"Reverse Transcriptase Polymerase Chain Reaction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D043323","descriptor_name":"alpha-Mannosidase","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1128/aem.01058-07","doi":"https://doi.org/10.1128/aem.01058-07","is_oa":false,"landing_page_url":"https://doi.org/10.1128/aem.01058-07","pdf_url":null,"source":{"id":"https://openalex.org/S158228368","display_name":"Applied and Environmental Microbiology","issn_l":"0099-2240","issn":["0099-2240","1070-6291","1098-5336"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Applied and Environmental Microbiology","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:1833607","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2258586","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmid:18083888","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18083888","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Applied and environmental microbiology","raw_type":"Comparative Study"},{"id":"pmh:oai:pubmedcentral.nih.gov:2258586","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC2258586/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Appl Environ Microbiol","raw_type":"Text"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.336.732","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.336.732","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://aem.asm.org/content/74/4/1076.full.pdf","raw_type":"text"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:1833607","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2258586","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.5683000087738037}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":49,"referenced_works":["https://openalex.org/W17439892","https://openalex.org/W175636568","https://openalex.org/W307068203","https://openalex.org/W561951869","https://openalex.org/W1426890344","https://openalex.org/W1892238403","https://openalex.org/W1967649036","https://openalex.org/W1975044278","https://openalex.org/W1975351631","https://openalex.org/W1985282072","https://openalex.org/W1987164215","https://openalex.org/W1991109615","https://openalex.org/W1998373746","https://openalex.org/W1999196262","https://openalex.org/W2001614383","https://openalex.org/W2002707187","https://openalex.org/W2003520957","https://openalex.org/W2004984207","https://openalex.org/W2007432405","https://openalex.org/W2008693575","https://openalex.org/W2027848320","https://openalex.org/W2034194918","https://openalex.org/W2034766668","https://openalex.org/W2034969165","https://openalex.org/W2035542094","https://openalex.org/W2039722369","https://openalex.org/W2061897068","https://openalex.org/W2062451682","https://openalex.org/W2068718117","https://openalex.org/W2069851790","https://openalex.org/W2077005247","https://openalex.org/W2082771996","https://openalex.org/W2084735047","https://openalex.org/W2086616742","https://openalex.org/W2094341257","https://openalex.org/W2094945468","https://openalex.org/W2095830750","https://openalex.org/W2107632694","https://openalex.org/W2110796052","https://openalex.org/W2119861230","https://openalex.org/W2129875490","https://openalex.org/W2134566626","https://openalex.org/W2147483959","https://openalex.org/W2153157597","https://openalex.org/W2171121268","https://openalex.org/W2239054664","https://openalex.org/W2314761304","https://openalex.org/W2399400267","https://openalex.org/W2407995105"],"related_works":["https://openalex.org/W3174898703","https://openalex.org/W3116105068","https://openalex.org/W2004984207","https://openalex.org/W2048087531","https://openalex.org/W4399368082","https://openalex.org/W2002707187","https://openalex.org/W2187122410","https://openalex.org/W2006403630","https://openalex.org/W7112303249","https://openalex.org/W2095830750"],"abstract_inverted_index":{"The":[0],"production":[1],"by":[2,16,24,92],"filamentous":[3,147],"fungi":[4],"of":[5,27,71,81,83,95,119,129],"therapeutic":[6,144],"glycoproteins":[7],"intended":[8],"for":[9,111],"use":[10],"in":[11,20,44,51,115,146],"mammals":[12],"is":[13,132],"held":[14],"back":[15],"the":[17,25,28,52,69,84,93,120,136],"inherent":[18],"difference":[19],"protein":[21,41],"N-glycosylation":[22],"and":[23,63],"inability":[26],"fungal":[29,53,121,130],"cell":[30],"to":[31,138],"modify":[32],"proteins":[33,58,145],"with":[34,74],"mammalian":[35],"glycosylation":[36,122,131],"structures.":[37],"Here,":[38],"we":[39,106],"report":[40],"N-glycan":[42],"engineering":[43],"two":[45],"Aspergillus":[46],"species.":[47],"We":[48],"functionally":[49],"expressed":[50],"hosts":[54],"heterologous":[55],"chimeric":[56],"fusion":[57],"containing":[59],"different":[60],"localization":[61],"peptides":[62],"catalytic":[64],"domains.":[65],"This":[66,87,127],"strategy":[67],"allowed":[68],"isolation":[70],"a":[72,75,96,133],"strain":[73,88],"functional":[76,97],"alpha-1,2-mannosidase":[77],"producing":[78],"increased":[79],"amounts":[80],"N-glycans":[82,142],"Man5GlcNAc2":[85],"type.":[86],"was":[89],"further":[90],"engineered":[91],"introduction":[94],"GlcNAc":[98],"transferase":[99],"I":[100],"construct":[101],"yielding":[102,124],"GlcNAcMan5GlcNac2":[103],"N-glycans.":[104,126],"Additionally,":[105],"deleted":[107],"algC":[108],"genes":[109],"coding":[110],"an":[112,116],"enzyme":[113],"involved":[114],"early":[117],"step":[118,134],"pathway":[123],"Man3GlcNAc2":[125],"modification":[128],"toward":[135],"ability":[137],"produce":[139],"humanized":[140],"complex":[141],"on":[143],"fungi.":[148]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":5},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":4},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":5},{"year":2015,"cited_by_count":6},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":5},{"year":2012,"cited_by_count":5}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}