{"id":"https://openalex.org/W2106055152","doi":"https://doi.org/10.1002/art.39436","title":"Patterns of Coexisting Lesions Detected on Magnetic Resonance Imaging and Relationship to Incident Knee Osteoarthritis: The Multicenter Osteoarthritis Study","display_name":"Patterns of Coexisting Lesions Detected on Magnetic Resonance Imaging and Relationship to Incident Knee Osteoarthritis: The Multicenter Osteoarthritis Study","publication_year":2015,"publication_date":"2015-09-28","ids":{"openalex":"https://openalex.org/W2106055152","doi":"https://doi.org/10.1002/art.39436","mag":"2106055152","pmid":"https://pubmed.ncbi.nlm.nih.gov/26414125"},"language":"en","primary_location":{"id":"doi:10.1002/art.39436","doi":"https://doi.org/10.1002/art.39436","is_oa":false,"landing_page_url":"https://doi.org/10.1002/art.39436","pdf_url":null,"source":{"id":"https://openalex.org/S4210186158","display_name":"Arthritis & Rheumatology","issn_l":"2326-5191","issn":["2326-5191","2326-5205"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Arthritis & Rheumatology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4661091","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5042059087","display_name":"Jingbo Niu","orcid":"https://orcid.org/0000-0002-6170-1965","observed_orcids":["https://orcid.org/0000-0002-6170-1965"]},"institutions":[{"id":"https://openalex.org/I111088046","display_name":"Boston University","ror":"https://ror.org/05qwgg493","country_code":"US","type":"education","lineage":["https://openalex.org/I111088046"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Jingbo Niu","raw_affiliation_strings":["Boston University School of Medicine Boston Massachusetts","Boston University, School of Medicine, Boston, Massachusetts"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Boston University School of Medicine Boston Massachusetts","institution_ids":["https://openalex.org/I111088046"]},{"raw_affiliation_string":"Boston University, School of Medicine, Boston, Massachusetts","institution_ids":["https://openalex.org/I111088046"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023227957","display_name":"David T. Felson","orcid":"https://orcid.org/0000-0002-2668-2447","observed_orcids":["https://orcid.org/0000-0002-2668-2447"]},"institutions":[{"id":"https://openalex.org/I111088046","display_name":"Boston University","ror":"https://ror.org/05qwgg493","country_code":"US","type":"education","lineage":["https://openalex.org/I111088046"]},{"id":"https://openalex.org/I28407311","display_name":"University of Manchester","ror":"https://ror.org/027m9bs27","country_code":"GB","type":"education","lineage":["https://openalex.org/I28407311"]}],"countries":["GB","US"],"is_corresponding":false,"raw_author_name":"David T. Felson","raw_affiliation_strings":["Boston University School of Medicine, Boston, Massachusetts, and University of Manchester Manchester UK","Boston University School of Medicine, Boston, Massachusetts, and University of Manchester, Manchester, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Boston University School of Medicine, Boston, Massachusetts, and University of Manchester Manchester UK","institution_ids":["https://openalex.org/I111088046","https://openalex.org/I28407311"]},{"raw_affiliation_string":"Boston University School of Medicine, Boston, Massachusetts, and University of Manchester, Manchester, UK","institution_ids":["https://openalex.org/I111088046","https://openalex.org/I28407311"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046252909","display_name":"Tuhina Neogi","orcid":"https://orcid.org/0000-0002-9515-1711","observed_orcids":["https://orcid.org/0000-0002-9515-1711"]},"institutions":[{"id":"https://openalex.org/I111088046","display_name":"Boston University","ror":"https://ror.org/05qwgg493","country_code":"US","type":"education","lineage":["https://openalex.org/I111088046"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tuhina Neogi","raw_affiliation_strings":["Boston University School of Medicine Boston Massachusetts","Boston University, School of Medicine, Boston, Massachusetts"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Boston University School of Medicine Boston Massachusetts","institution_ids":["https://openalex.org/I111088046"]},{"raw_affiliation_string":"Boston University, School of Medicine, Boston, Massachusetts","institution_ids":["https://openalex.org/I111088046"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008680318","display_name":"Michael C. Nevitt","orcid":"https://orcid.org/0000-0002-6988-7530","observed_orcids":["https://orcid.org/0000-0002-6988-7530"]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael C. Nevitt","raw_affiliation_strings":["University of California San Francisco"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of California San Francisco","institution_ids":["https://openalex.org/I180670191"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069018938","display_name":"Ali Guermazi","orcid":"https://orcid.org/0000-0002-9374-8266","observed_orcids":["https://orcid.org/0000-0002-9374-8266"]},"institutions":[{"id":"https://openalex.org/I111088046","display_name":"Boston University","ror":"https://ror.org/05qwgg493","country_code":"US","type":"education","lineage":["https://openalex.org/I111088046"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ali Guermazi","raw_affiliation_strings":["Boston University School of Medicine and Boston Core Imaging Lab, LLC Boston Massachusetts"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Boston University School of Medicine and Boston Core Imaging Lab, LLC Boston Massachusetts","institution_ids":["https://openalex.org/I111088046"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057463669","display_name":"Frank W. Roemer","orcid":"https://orcid.org/0000-0001-9238-7350","observed_orcids":["https://orcid.org/0000-0001-9238-7350","https://orcid.org/0000-0003-4684-8675"]},"institutions":[{"id":"https://openalex.org/I111088046","display_name":"Boston University","ror":"https://ror.org/05qwgg493","country_code":"US","type":"education","lineage":["https://openalex.org/I111088046"]},{"id":"https://openalex.org/I181369854","display_name":"Friedrich-Alexander-Universit\u00e4t Erlangen-N\u00fcrnberg","ror":"https://ror.org/00f7hpc57","country_code":"DE","type":"education","lineage":["https://openalex.org/I181369854"]}],"countries":["DE","US"],"is_corresponding":false,"raw_author_name":"Frank Roemer","raw_affiliation_strings":["Boston University School of Medicine and Boston Core Imaging Lab, LLC, Boston, Massachusetts, and University of Erlangen\u2013Nuremberg Erlangen, Germany","Boston University School of Medicine and Boston Core Imaging Lab, LLC, Boston, Massachusetts, and University of Erlangen-Nuremberg; Erlangen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Boston University School of Medicine and Boston Core Imaging Lab, LLC, Boston, Massachusetts, and University of Erlangen\u2013Nuremberg Erlangen, Germany","institution_ids":["https://openalex.org/I111088046","https://openalex.org/I181369854"]},{"raw_affiliation_string":"Boston University School of Medicine and Boston Core Imaging Lab, LLC, Boston, Massachusetts, and University of Erlangen-Nuremberg; Erlangen, Germany","institution_ids":["https://openalex.org/I111088046","https://openalex.org/I181369854"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069988352","display_name":"Cora Elizabeth Lewis","orcid":"https://orcid.org/0000-0002-2301-5796","observed_orcids":["https://orcid.org/0000-0002-2301-5796"]},"institutions":[{"id":"https://openalex.org/I17301866","display_name":"University of Alabama","ror":"https://ror.org/03xrrjk67","country_code":"US","type":"education","lineage":["https://openalex.org/I17301866"]},{"id":"https://openalex.org/I32389192","display_name":"University of Alabama at Birmingham","ror":"https://ror.org/008s83205","country_code":"US","type":"education","lineage":["https://openalex.org/I32389192"]},{"id":"https://openalex.org/I4390039250","display_name":"UAB Medicine","ror":"https://ror.org/036554539","country_code":null,"type":"healthcare","lineage":["https://openalex.org/I4390039250"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Cora E. Lewis","raw_affiliation_strings":["University of Alabama School of Medicine Birmingham","University of Alabama School of Medicine; Birmingham"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Alabama School of Medicine Birmingham","institution_ids":["https://openalex.org/I17301866","https://openalex.org/I32389192","https://openalex.org/I4390039250"]},{"raw_affiliation_string":"University of Alabama School of Medicine; Birmingham","institution_ids":["https://openalex.org/I32389192","https://openalex.org/I4390039250"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050556211","display_name":"James C. Torner","orcid":"https://orcid.org/0000-0003-0979-4874","observed_orcids":["https://orcid.org/0000-0003-0979-4874"]},"institutions":[{"id":"https://openalex.org/I126307644","display_name":"University of Iowa","ror":"https://ror.org/036jqmy94","country_code":"US","type":"education","lineage":["https://openalex.org/I126307644"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"James Torner","raw_affiliation_strings":["University of Iowa Iowa City","University of Iowa, Iowa City"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Iowa Iowa City","institution_ids":["https://openalex.org/I126307644"]},{"raw_affiliation_string":"University of Iowa, Iowa City","institution_ids":["https://openalex.org/I126307644"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5015051319","display_name":"Yuqing Zhang","orcid":"https://orcid.org/0000-0001-7638-0888","observed_orcids":["https://orcid.org/0000-0001-7638-0888","https://orcid.org/0000-0001-7954-1149","https://orcid.org/0000-0002-7218-7201","https://orcid.org/0000-0002-6318-3575"]},"institutions":[{"id":"https://openalex.org/I111088046","display_name":"Boston University","ror":"https://ror.org/05qwgg493","country_code":"US","type":"education","lineage":["https://openalex.org/I111088046"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yuqing Zhang","raw_affiliation_strings":["Boston University School of Medicine Boston Massachusetts","Boston University, School of Medicine, Boston, Massachusetts"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Boston University School of Medicine Boston Massachusetts","institution_ids":["https://openalex.org/I111088046"]},{"raw_affiliation_string":"Boston University, School of Medicine, Boston, Massachusetts","institution_ids":["https://openalex.org/I111088046"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":8,"corresponding_author_ids":["https://openalex.org/A5042059087"],"corresponding_institution_ids":["https://openalex.org/I111088046"],"apc_list":{"value":5190,"currency":"USD","value_usd":5190},"apc_paid":null,"fwci":1.94,"has_fulltext":false,"cited_by_count":32,"citation_normalized_percentile":{"value":0.84913641,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"67","issue":"12","first_page":"3158","last_page":"3165"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10105","display_name":"Osteoarthritis Treatment and Mechanisms","score":0.986299991607666,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10105","display_name":"Osteoarthritis Treatment and Mechanisms","score":0.986299991607666,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11218","display_name":"Hip disorders and treatments","score":0.0024999999441206455,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10442","display_name":"Knee injuries and reconstruction techniques","score":0.002400000113993883,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/knee-osteoarthritis","display_name":"knee osteoarthritis","score":0.9980000257492065},{"id":"https://openalex.org/keywords/incident-osteoarthritis","display_name":"incident osteoarthritis","score":0.8709999918937683},{"id":"https://openalex.org/keywords/latent-class-analysis","display_name":"latent class analysis","score":0.7889999747276306},{"id":"https://openalex.org/keywords/tibiofemoral-joint","display_name":"tibiofemoral joint","score":0.878000020980835},{"id":"https://openalex.org/keywords/patellofemoral-joint","display_name":"patellofemoral joint","score":1.0},{"id":"https://openalex.org/keywords/meniscus-injury","display_name":"meniscal injury","score":0.6959999799728394},{"id":"https://openalex.org/keywords/meniscus-tear","display_name":"meniscal tears","score":0.8100000023841858},{"id":"https://openalex.org/keywords/meniscal-extrusion","display_name":"meniscal extrusion","score":0.9509999752044678},{"id":"https://openalex.org/keywords/bone-marrow-lesions","display_name":"bone marrow lesions","score":0.7490000128746033},{"id":"https://openalex.org/keywords/synovitis","display_name":"synovitis","score":0.8980000019073486},{"id":"https://openalex.org/keywords/cartilage-damage","display_name":"cartilage damage","score":0.7480000257492065},{"id":"https://openalex.org/keywords/synovial-effusion","display_name":"synovial effusion","score":0.7749999761581421},{"id":"https://openalex.org/keywords/osteoarthritis-risk-factors","display_name":"osteoarthritis risk factors","score":0.722000002861023}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.911663293838501},{"id":"https://openalex.org/C2776164576","wikidata":"https://www.wikidata.org/wiki/Q62736","display_name":"Osteoarthritis","level":3,"score":0.8143845796585083},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.6612218618392944},{"id":"https://openalex.org/C2779244835","wikidata":"https://www.wikidata.org/wiki/Q538432","display_name":"Synovitis","level":3,"score":0.6438860297203064},{"id":"https://openalex.org/C156957248","wikidata":"https://www.wikidata.org/wiki/Q1862216","display_name":"Odds ratio","level":2,"score":0.5840471386909485},{"id":"https://openalex.org/C36454342","wikidata":"https://www.wikidata.org/wiki/Q245341","display_name":"Radiography","level":2,"score":0.5832211971282959},{"id":"https://openalex.org/C2908736133","wikidata":"https://www.wikidata.org/wiki/Q37425","display_name":"Knee Joint","level":2,"score":0.5418416261672974},{"id":"https://openalex.org/C2778573185","wikidata":"https://www.wikidata.org/wiki/Q1499629","display_name":"Joint effusion","level":3,"score":0.5349757671356201},{"id":"https://openalex.org/C188816634","wikidata":"https://www.wikidata.org/wiki/Q2113324","display_name":"Prospective cohort study","level":2,"score":0.44561177492141724},{"id":"https://openalex.org/C189178095","wikidata":"https://www.wikidata.org/wiki/Q15834833","display_name":"Meniscus","level":3,"score":0.4340876042842865},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.41039901971817017},{"id":"https://openalex.org/C2777077863","wikidata":"https://www.wikidata.org/wiki/Q170990","display_name":"Arthritis","level":2,"score":0.3943250775337219},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3686571717262268},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.2896016240119934},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.1926274597644806},{"id":"https://openalex.org/C61511704","wikidata":"https://www.wikidata.org/wiki/Q1671857","display_name":"Incidence (geometry)","level":2,"score":0.06850877404212952},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001853","descriptor_name":"Bone Marrow","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D001853","descriptor_name":"Bone Marrow","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D001853","descriptor_name":"Bone Marrow","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D002358","descriptor_name":"Cartilage, Articular","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D002358","descriptor_name":"Cartilage, Articular","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D002358","descriptor_name":"Cartilage, Articular","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007719","descriptor_name":"Knee Joint","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D007719","descriptor_name":"Knee Joint","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D007719","descriptor_name":"Knee Joint","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008592","descriptor_name":"Menisci, Tibial","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D008592","descriptor_name":"Menisci, Tibial","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D008592","descriptor_name":"Menisci, Tibial","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011859","descriptor_name":"Radiography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011859","descriptor_name":"Radiography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011859","descriptor_name":"Radiography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013585","descriptor_name":"Synovitis","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D013585","descriptor_name":"Synovitis","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D013585","descriptor_name":"Synovitis","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D015331","descriptor_name":"Cohort Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015331","descriptor_name":"Cohort Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015331","descriptor_name":"Cohort Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016015","descriptor_name":"Logistic Models","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016015","descriptor_name":"Logistic Models","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016015","descriptor_name":"Logistic Models","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018450","descriptor_name":"Disease Progression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018450","descriptor_name":"Disease Progression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018450","descriptor_name":"Disease Progression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020370","descriptor_name":"Osteoarthritis, Knee","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D020370","descriptor_name":"Osteoarthritis, Knee","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D020370","descriptor_name":"Osteoarthritis, Knee","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D020370","descriptor_name":"Osteoarthritis, Knee","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D020370","descriptor_name":"Osteoarthritis, Knee","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D020370","descriptor_name":"Osteoarthritis, Knee","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D042241","descriptor_name":"Early Diagnosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D042241","descriptor_name":"Early Diagnosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D042241","descriptor_name":"Early Diagnosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057071","descriptor_name":"Patellofemoral Joint","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D057071","descriptor_name":"Patellofemoral Joint","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D057071","descriptor_name":"Patellofemoral Joint","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1002/art.39436","doi":"https://doi.org/10.1002/art.39436","is_oa":false,"landing_page_url":"https://doi.org/10.1002/art.39436","pdf_url":null,"source":{"id":"https://openalex.org/S4210186158","display_name":"Arthritis & Rheumatology","issn_l":"2326-5191","issn":["2326-5191","2326-5205"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Arthritis & Rheumatology","raw_type":"journal-article"},{"id":"pmid:26414125","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/26414125","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Arthritis & rheumatology (Hoboken, N.J.)","raw_type":"Journal Article"},{"id":"pmh:oai:pure.atira.dk:openaire_cris_publications/3344ebd5-37a8-46cf-a6d9-4e0548216aa0","doi":null,"is_oa":false,"landing_page_url":"https://research.manchester.ac.uk/en/publications/3344ebd5-37a8-46cf-a6d9-4e0548216aa0","pdf_url":null,"source":{"id":"https://openalex.org/S4306400662","display_name":"Research Explorer (The University of Manchester)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I28407311","host_organization_name":"University of Manchester","host_organization_lineage":["https://openalex.org/I28407311"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Niu, J, Felson, D T, Neogi, T, Nevitt, M C, Guermazi, A, Roemer, F, Lewis, C E, Torner, J & Zhang, Y 2015, 'Patterns of Co-existing MRI lesions and incident knee osteoarthritis: The MOST Study.', Arthritis & rheumatology (Hoboken, N.J.), vol. 67, no. 12, pp. 3158-3165. https://doi.org/10.1002/art.39436","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:pubmedcentral.nih.gov:4661091","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4661091","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Arthritis Rheumatol","raw_type":"Text"},{"id":"pmh:oai:escholarship.org:ark:/13030/qt01q5d530","doi":null,"is_oa":false,"landing_page_url":"https://escholarship.org/uc/item/01q5d530","pdf_url":null,"source":{"id":"https://openalex.org/S4306400115","display_name":"eScholarship (California Digital Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2801248553","host_organization_name":"California Digital Library","host_organization_lineage":["https://openalex.org/I2801248553"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Arthritis & Rheumatology, vol 67, iss 12","raw_type":"article"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:4661091","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4661091","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Arthritis Rheumatol","raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9763000011444092}],"sustainable_development_goals_aurora":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.6700000166893005}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1006268158","display_name":null,"funder_award_id":"U01-AG-1-8832","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"},{"id":"https://openalex.org/G1385035505","display_name":null,"funder_award_id":"U01-AG-18820","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"},{"id":"https://openalex.org/G158963981","display_name":null,"funder_award_id":"P60 AR 47785","funder_id":"https://openalex.org/F4320337362","funder_display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases"},{"id":"https://openalex.org/G1931028181","display_name":"Central Sensitization in Post-Knee Replacement Pain and Relation to OA Pathology","funder_award_id":"4r01ar062506-05","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G2031867652","display_name":null,"funder_award_id":"U01 AG19079","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"},{"id":"https://openalex.org/G307378974","display_name":null,"funder_award_id":"R01-AR-062506","funder_id":"https://openalex.org/F4320337362","funder_display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases"},{"id":"https://openalex.org/G3306721896","display_name":null,"funder_award_id":"P60 AR047785","funder_id":"https://openalex.org/F4320337362","funder_display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases"},{"id":"https://openalex.org/G333184648","display_name":null,"funder_award_id":"U01\u2010AG\u201018947","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"},{"id":"https://openalex.org/G4619403859","display_name":"Multicenter Osteoarthritis Study (MOST) Second Renewal - UAB Clinical Center","funder_award_id":"5u01ag018947-18","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G4993145128","display_name":null,"funder_award_id":"U01AG018832","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"},{"id":"https://openalex.org/G501991607","display_name":null,"funder_award_id":"(U01 AG018947","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"},{"id":"https://openalex.org/G5090531137","display_name":"Multicenter Osteoarthritis Study (MOST) Second Renewal","funder_award_id":"U01AG019069","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"},{"id":"https://openalex.org/G8728304151","display_name":"Multicenter Osteoarthritis Study (MOST) Second Renewal - Boston University","funder_award_id":"U01AG018820","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337337","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11"},{"id":"https://openalex.org/F4320337362","display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases","ror":"https://ror.org/006zn3t30"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":20,"referenced_works":["https://openalex.org/W1538222952","https://openalex.org/W1545129952","https://openalex.org/W1598612182","https://openalex.org/W1967057044","https://openalex.org/W1987537066","https://openalex.org/W1991947119","https://openalex.org/W1992691752","https://openalex.org/W2018819772","https://openalex.org/W2020632067","https://openalex.org/W2022306341","https://openalex.org/W2030138474","https://openalex.org/W2045767667","https://openalex.org/W2088697515","https://openalex.org/W2098835452","https://openalex.org/W2107657275","https://openalex.org/W2109228592","https://openalex.org/W2112870271","https://openalex.org/W2118903184","https://openalex.org/W2138008655","https://openalex.org/W2140513563"],"related_works":["https://openalex.org/W2365087054","https://openalex.org/W142113884","https://openalex.org/W2183091916","https://openalex.org/W2909283968","https://openalex.org/W2137934350","https://openalex.org/W1991977691","https://openalex.org/W2020615358","https://openalex.org/W2289149327","https://openalex.org/W2368891483","https://openalex.org/W2419263421"],"abstract_inverted_index":{"OBJECTIVE:":[0],"To":[1],"identify":[2],"patterns":[3,258],"of":[4,18,27,90,113,117,182,211,232,259,271,287],"coexisting":[5,260],"lesions":[6,30,92,171,198],"seen":[7],"on":[8],"magnetic":[9],"resonance":[10],"imaging":[11],"(MRI)":[12],"in":[13,40,54,60,93,124,142,150,157,187,214,235,244,284,290],"knees":[14,137,195],"that":[15,221],"are":[16],"free":[17],"radiographic":[19,56,122],"osteoarthritis":[20],"(OA)":[21],"and":[22,64,107,176,205,242,252],"to":[23,31,86,193,269,279],"examine":[24],"the":[25,41,62,88,125,143,151,158,188,194,200,215,222,236,245,285],"relationship":[26],"these":[28,118],"MRI-detected":[29],"incident":[32,121,140,148,183,233,288],"OA.":[33],"METHODS:":[34],"Study":[35],"subjects":[36],"were":[37,161,202,239,274],"individuals":[38],"enrolled":[39],"Multicenter":[42],"Osteoarthritis":[43],"Study,":[44],"a":[45,80,110,281],"prospective":[46],"cohort":[47],"study.":[48],"In":[49],"each":[50,94],"subject,":[51],"1":[52],"knee":[53,272],"which":[55,263],"OA":[57,123,186],"was":[58,69,128,218],"absent":[59],"both":[61],"tibiofemoral":[63,144,159,184,291],"patellofemoral":[65,152,216,237,293],"joints":[66],"at":[67],"baseline":[68],"selected":[70],"for":[71,75],"study,":[72],"with":[73,120,139,147,196,247,267],"followup":[74],"84":[76],"months.":[77],"We":[78],"used":[79],"novel":[81],"approach,":[82],"latent":[83,155],"class":[84],"analysis,":[85],"group":[87],"constellation":[89],"MRI":[91,261],"joint,":[95,145],"i.e.,":[96],"cartilage":[97],"damage,":[98],"bone":[99],"marrow":[100],"lesion,":[101],"meniscal":[102,104,174,227],"tear,":[103],"extrusion,":[105],"synovitis,":[106],"effusion,":[108],"into":[109],"manageable":[111],"number":[112],"subgroups.":[114],"The":[115,179,229],"association":[116],"subgroups":[119,156,191,213,246],"same":[126],"joint":[127,160,185,217,238],"assessed":[129],"using":[130],"logistic":[131],"regression.":[132],"RESULTS:":[133],"Among":[134],"885":[135],"eligible":[136],"(203":[138],"disease":[141,149,234,289],"64":[146],"joint),":[153],"4":[154,212],"identified":[162],"(described":[163],"briefly":[164],"as":[165,199],"minimal":[166,197],"lesions,":[167,169,249,251,254,262],"mild":[168,248],"moderate":[170,250],"[but":[172],"limited":[173,226],"lesions],":[175],"severe":[177,253],"lesions).":[178],"odds":[180,230],"ratios":[181,231],"latter":[189],"3":[190],"(compared":[192],"referent)":[201],"5.6,":[203],"1.8,":[204],"5.0,":[206],"respectively.":[207,255],"A":[208],"similar":[209],"set":[210],"identified,":[219],"except":[220],"fourth":[223],"subgroup":[224],"had":[225],"lesions.":[228],"3.8,":[240],"5.1,":[241],"13.7":[243],"CONCLUSION:":[256],"Different":[257],"have":[264],"different":[265,282],"implications":[266],"regard":[268],"risk":[270],"OA,":[273],"identified.":[275],"Meniscal":[276],"damage":[277],"seemed":[278],"play":[280],"role":[283],"development":[286],"versus":[292],"joints.":[294]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":5},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2016-06-24T00:00:00"}