{"id":"https://openalex.org/W2105923985","doi":"https://doi.org/10.1007/s00011-012-0529-4","title":"Liver X receptor activation attenuates plaque formation and improves vasomotor function of the aortic artery in atherosclerotic ApoE\u2212/\u2212 mice","display_name":"Liver X receptor activation attenuates plaque formation and improves vasomotor function of the aortic artery in atherosclerotic ApoE\u2212/\u2212 mice","publication_year":2012,"publication_date":"2012-07-25","ids":{"openalex":"https://openalex.org/W2105923985","doi":"https://doi.org/10.1007/s00011-012-0529-4","mag":"2105923985","pmid":"https://pubmed.ncbi.nlm.nih.gov/22833121"},"language":"en","primary_location":{"id":"doi:10.1007/s00011-012-0529-4","doi":"https://doi.org/10.1007/s00011-012-0529-4","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s00011-012-0529-4","pdf_url":null,"source":{"id":"https://openalex.org/S55943811","display_name":"Inflammation Research","issn_l":"1023-3830","issn":["1023-3830","1420-908X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Inflammation Research","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5057220805","display_name":"Jianghong Chen","orcid":"https://orcid.org/0000-0003-4734-4559","observed_orcids":["https://orcid.org/0000-0003-4734-4559"]},"institutions":[{"id":"https://openalex.org/I4210158926","display_name":"Xijing Hospital","ror":"https://ror.org/05cqe9350","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210158926"]},{"id":"https://openalex.org/I9916479","display_name":"Air Force Medical University","ror":"https://ror.org/00ms48f15","country_code":"CN","type":"education","lineage":["https://openalex.org/I9916479"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jianghong Chen","raw_affiliation_strings":["Department of Cardiology, Xijing Hospital, Fourth Military Medical University, Xi'an 710032, Shaanxi, China","Fourth Military Medical University#TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, Xijing Hospital, Fourth Military Medical University, Xi'an 710032, Shaanxi, China","institution_ids":["https://openalex.org/I4210158926","https://openalex.org/I9916479"]},{"raw_affiliation_string":"Fourth Military Medical University#TAB#","institution_ids":["https://openalex.org/I9916479"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034916375","display_name":"Li Zhao","orcid":"https://orcid.org/0000-0002-1318-3833","observed_orcids":["https://orcid.org/0000-0002-1318-3833"]},"institutions":[{"id":"https://openalex.org/I4210158926","display_name":"Xijing Hospital","ror":"https://ror.org/05cqe9350","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210158926"]},{"id":"https://openalex.org/I9916479","display_name":"Air Force Medical University","ror":"https://ror.org/00ms48f15","country_code":"CN","type":"education","lineage":["https://openalex.org/I9916479"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Li Zhao","raw_affiliation_strings":["Department of Cardiology, Xijing Hospital, Fourth Military Medical University, Xi\u2019an, 710032, Shaanxi, China","Fourth Military Medical University#TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, Xijing Hospital, Fourth Military Medical University, Xi\u2019an, 710032, Shaanxi, China","institution_ids":["https://openalex.org/I4210158926","https://openalex.org/I9916479"]},{"raw_affiliation_string":"Fourth Military Medical University#TAB#","institution_ids":["https://openalex.org/I9916479"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100732038","display_name":"Dongdong Sun","orcid":"https://orcid.org/0000-0003-2147-3977","observed_orcids":["https://orcid.org/0000-0003-2147-3977"]},"institutions":[{"id":"https://openalex.org/I4210158926","display_name":"Xijing Hospital","ror":"https://ror.org/05cqe9350","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210158926"]},{"id":"https://openalex.org/I9916479","display_name":"Air Force Medical University","ror":"https://ror.org/00ms48f15","country_code":"CN","type":"education","lineage":["https://openalex.org/I9916479"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Dongdong Sun","raw_affiliation_strings":["Department of Cardiology, Xijing Hospital, Fourth Military Medical University, Xi\u2019an, 710032, Shaanxi, China","Fourth Military Medical University#TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, Xijing Hospital, Fourth Military Medical University, Xi\u2019an, 710032, Shaanxi, China","institution_ids":["https://openalex.org/I4210158926","https://openalex.org/I9916479"]},{"raw_affiliation_string":"Fourth Military Medical University#TAB#","institution_ids":["https://openalex.org/I9916479"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029305030","display_name":"Kazim H Narsinh","orcid":"https://orcid.org/0000-0002-2019-5461","observed_orcids":["https://orcid.org/0000-0002-2019-5461"]},"institutions":[{"id":"https://openalex.org/I4210137306","display_name":"Stanford Medicine","ror":"https://ror.org/03mtd9a03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]},{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kazim Narsinh","raw_affiliation_strings":["Department of Radiology, Stanford Medical Center, Stanford University, Stanford, USA","Stanford University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, Stanford Medical Center, Stanford University, Stanford, USA","institution_ids":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]},{"raw_affiliation_string":"Stanford University","institution_ids":["https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100703436","display_name":"Chunhong Li","orcid":"https://orcid.org/0000-0002-5164-2527","observed_orcids":["https://orcid.org/0000-0002-5164-2527"]},"institutions":[{"id":"https://openalex.org/I4210158926","display_name":"Xijing Hospital","ror":"https://ror.org/05cqe9350","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210158926"]},{"id":"https://openalex.org/I9916479","display_name":"Air Force Medical University","ror":"https://ror.org/00ms48f15","country_code":"CN","type":"education","lineage":["https://openalex.org/I9916479"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chunhong Li","raw_affiliation_strings":["Department of Cardiology, Xijing Hospital, Fourth Military Medical University, Xi\u2019an, 710032, Shaanxi, China","Fourth Military Medical University#TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, Xijing Hospital, Fourth Military Medical University, Xi\u2019an, 710032, Shaanxi, China","institution_ids":["https://openalex.org/I4210158926","https://openalex.org/I9916479"]},{"raw_affiliation_string":"Fourth Military Medical University#TAB#","institution_ids":["https://openalex.org/I9916479"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100459127","display_name":"Zheng Zhang","orcid":"https://orcid.org/0000-0002-5561-7601","observed_orcids":["https://orcid.org/0000-0002-5561-7601"]},"institutions":[{"id":"https://openalex.org/I4210158926","display_name":"Xijing Hospital","ror":"https://ror.org/05cqe9350","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210158926"]},{"id":"https://openalex.org/I9916479","display_name":"Air Force Medical University","ror":"https://ror.org/00ms48f15","country_code":"CN","type":"education","lineage":["https://openalex.org/I9916479"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zheng Zhang","raw_affiliation_strings":["Department of Cardiology, Xijing Hospital, Fourth Military Medical University, Xi\u2019an, 710032, Shaanxi, China","Fourth Military Medical University#TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, Xijing Hospital, Fourth Military Medical University, Xi\u2019an, 710032, Shaanxi, China","institution_ids":["https://openalex.org/I4210158926","https://openalex.org/I9916479"]},{"raw_affiliation_string":"Fourth Military Medical University#TAB#","institution_ids":["https://openalex.org/I9916479"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075563793","display_name":"Shun Qi","orcid":"https://orcid.org/0000-0002-2158-7061","observed_orcids":["https://orcid.org/0000-0002-2158-7061"]},"institutions":[{"id":"https://openalex.org/I4210158926","display_name":"Xijing Hospital","ror":"https://ror.org/05cqe9350","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210158926"]},{"id":"https://openalex.org/I9916479","display_name":"Air Force Medical University","ror":"https://ror.org/00ms48f15","country_code":"CN","type":"education","lineage":["https://openalex.org/I9916479"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shun Qi","raw_affiliation_strings":["Department of Radiology, Xijing Hospital, Fourth Military Medical University, Xi\u2019an, 710032, Shaanxi, China","Fourth Military Medical University#TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, Xijing Hospital, Fourth Military Medical University, Xi\u2019an, 710032, Shaanxi, China","institution_ids":["https://openalex.org/I4210158926","https://openalex.org/I9916479"]},{"raw_affiliation_string":"Fourth Military Medical University#TAB#","institution_ids":["https://openalex.org/I9916479"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111763366","display_name":"Guangquan Wei","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210158926","display_name":"Xijing Hospital","ror":"https://ror.org/05cqe9350","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210158926"]},{"id":"https://openalex.org/I9916479","display_name":"Air Force Medical University","ror":"https://ror.org/00ms48f15","country_code":"CN","type":"education","lineage":["https://openalex.org/I9916479"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Guangquan Wei","raw_affiliation_strings":["Department of Radiology, Xijing Hospital, Fourth Military Medical University, Xi\u2019an, 710032, Shaanxi, China","Fourth Military Medical University#TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, Xijing Hospital, Fourth Military Medical University, Xi\u2019an, 710032, Shaanxi, China","institution_ids":["https://openalex.org/I4210158926","https://openalex.org/I9916479"]},{"raw_affiliation_string":"Fourth Military Medical University#TAB#","institution_ids":["https://openalex.org/I9916479"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Weijie Li","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210158926","display_name":"Xijing Hospital","ror":"https://ror.org/05cqe9350","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210158926"]},{"id":"https://openalex.org/I9916479","display_name":"Air Force Medical University","ror":"https://ror.org/00ms48f15","country_code":"CN","type":"education","lineage":["https://openalex.org/I9916479"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Weijie Li","raw_affiliation_strings":["Department of Cardiology, Xijing Hospital, Fourth Military Medical University, Xi\u2019an, 710032, Shaanxi, China","Fourth Military Medical University#TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, Xijing Hospital, Fourth Military Medical University, Xi\u2019an, 710032, Shaanxi, China","institution_ids":["https://openalex.org/I4210158926","https://openalex.org/I9916479"]},{"raw_affiliation_string":"Fourth Military Medical University#TAB#","institution_ids":["https://openalex.org/I9916479"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101843576","display_name":"Wenyi Guo","orcid":"https://orcid.org/0000-0002-5334-1883","observed_orcids":["https://orcid.org/0000-0002-5334-1883"]},"institutions":[{"id":"https://openalex.org/I4210158926","display_name":"Xijing Hospital","ror":"https://ror.org/05cqe9350","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210158926"]},{"id":"https://openalex.org/I9916479","display_name":"Air Force Medical University","ror":"https://ror.org/00ms48f15","country_code":"CN","type":"education","lineage":["https://openalex.org/I9916479"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Wenyi Guo","raw_affiliation_strings":["Department of Cardiology, Xijing Hospital, Fourth Military Medical University, Xi\u2019an, 710032, Shaanxi, China","Fourth Military Medical University#TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, Xijing Hospital, Fourth Military Medical University, Xi\u2019an, 710032, Shaanxi, China","institution_ids":["https://openalex.org/I4210158926","https://openalex.org/I9916479"]},{"raw_affiliation_string":"Fourth Military Medical University#TAB#","institution_ids":["https://openalex.org/I9916479"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100705984","display_name":"Feng Cao","orcid":"https://orcid.org/0000-0002-1010-6429","observed_orcids":["https://orcid.org/0000-0002-1010-6429"]},"institutions":[{"id":"https://openalex.org/I4210158926","display_name":"Xijing Hospital","ror":"https://ror.org/05cqe9350","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210158926"]},{"id":"https://openalex.org/I9916479","display_name":"Air Force Medical University","ror":"https://ror.org/00ms48f15","country_code":"CN","type":"education","lineage":["https://openalex.org/I9916479"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Feng Cao","raw_affiliation_strings":["Department of Cardiology, Xijing Hospital, Fourth Military Medical University, Xi\u2019an, 710032, Shaanxi, China","Fourth Military Medical University#TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, Xijing Hospital, Fourth Military Medical University, Xi\u2019an, 710032, Shaanxi, China","institution_ids":["https://openalex.org/I4210158926","https://openalex.org/I9916479"]},{"raw_affiliation_string":"Fourth Military Medical University#TAB#","institution_ids":["https://openalex.org/I9916479"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5100705984","https://openalex.org/A5100732038","https://openalex.org/A5101843576"],"corresponding_institution_ids":["https://openalex.org/I4210158926","https://openalex.org/I9916479"],"apc_list":{"value":4790,"currency":"USD","value_usd":4790},"apc_paid":null,"fwci":0.7604,"has_fulltext":false,"cited_by_count":27,"citation_normalized_percentile":{"value":0.60996033,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":98},"biblio":{"volume":"61","issue":"12","first_page":"1299","last_page":"1307"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11618","display_name":"Cholesterol and Lipid Metabolism","score":0.5967000126838684,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11618","display_name":"Cholesterol and Lipid Metabolism","score":0.5967000126838684,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12955","display_name":"Atherosclerosis and Cardiovascular Diseases","score":0.3801000118255615,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10394","display_name":"Lipoproteins and Cardiovascular Health","score":0.0052999998442828655,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/liver-x-receptor","display_name":"liver X receptor","score":0.9269999861717224},{"id":"https://openalex.org/keywords/atherosclerosis","display_name":"atherosclerosis","score":0.9860000014305115},{"id":"https://openalex.org/keywords/atherosclerotic-plaque","display_name":"atherosclerotic plaque","score":0.8320000171661377},{"id":"https://openalex.org/keywords/apoe-deficient-mice","display_name":"ApoE-deficient mice","score":0.7770000100135803},{"id":"https://openalex.org/keywords/endothelial-function","display_name":"endothelial function","score":0.9169999957084656},{"id":"https://openalex.org/keywords/vasomotor-function","display_name":"vasomotor function","score":0.8709999918937683},{"id":"https://openalex.org/keywords/abca1","display_name":"ABCA1","score":0.9919999837875366},{"id":"https://openalex.org/keywords/abcg1","display_name":"ABCG1","score":1.0},{"id":"https://openalex.org/keywords/akt-phosphorylation","display_name":"Akt phosphorylation","score":0.8349999785423279},{"id":"https://openalex.org/keywords/enos-phosphorylation","display_name":"eNOS phosphorylation","score":0.9909999966621399},{"id":"https://openalex.org/keywords/lipid-profile","display_name":"lipid profile","score":0.7710000276565552},{"id":"https://openalex.org/keywords/triglycerides","display_name":"triglycerides","score":0.7590000033378601},{"id":"https://openalex.org/keywords/aortic-endothelial-cells","display_name":"aortic endothelial cells","score":0.6549999713897705}],"concepts":[{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.7217989563941956},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.7130586504936218},{"id":"https://openalex.org/C167400880","wikidata":"https://www.wikidata.org/wiki/Q3454539","display_name":"Liver X receptor","level":5,"score":0.611915647983551},{"id":"https://openalex.org/C2776330080","wikidata":"https://www.wikidata.org/wiki/Q21113668","display_name":"ABCG1","level":5,"score":0.5836951732635498},{"id":"https://openalex.org/C2778326061","wikidata":"https://www.wikidata.org/wiki/Q1761022","display_name":"Enos","level":4,"score":0.581256628036499},{"id":"https://openalex.org/C57089818","wikidata":"https://www.wikidata.org/wiki/Q424728","display_name":"Apolipoprotein E","level":3,"score":0.5804558396339417},{"id":"https://openalex.org/C2777704780","wikidata":"https://www.wikidata.org/wiki/Q21115210","display_name":"ABCA1","level":4,"score":0.5382205843925476},{"id":"https://openalex.org/C2779980429","wikidata":"https://www.wikidata.org/wiki/Q101004","display_name":"Aorta","level":2,"score":0.49697044491767883},{"id":"https://openalex.org/C2778938600","wikidata":"https://www.wikidata.org/wiki/Q389934","display_name":"Agonist","level":3,"score":0.4960084855556488},{"id":"https://openalex.org/C2780972559","wikidata":"https://www.wikidata.org/wiki/Q550061","display_name":"Endothelial dysfunction","level":2,"score":0.4948388934135437},{"id":"https://openalex.org/C2776992346","wikidata":"https://www.wikidata.org/wiki/Q111140","display_name":"Endothelium","level":2,"score":0.473678857088089},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4480403959751129},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.3352184593677521},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.2687804102897644},{"id":"https://openalex.org/C519581460","wikidata":"https://www.wikidata.org/wiki/Q207843","display_name":"Nitric oxide","level":2,"score":0.16527605056762695},{"id":"https://openalex.org/C2777622882","wikidata":"https://www.wikidata.org/wiki/Q417619","display_name":"Nitric oxide synthase","level":3,"score":0.12571802735328674},{"id":"https://openalex.org/C63932345","wikidata":"https://www.wikidata.org/wiki/Q422500","display_name":"Nuclear receptor","level":4,"score":0.09589836001396179},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.07944709062576294},{"id":"https://openalex.org/C149011108","wikidata":"https://www.wikidata.org/wiki/Q652985","display_name":"Transporter","level":3,"score":0.0},{"id":"https://openalex.org/C86339819","wikidata":"https://www.wikidata.org/wiki/Q407384","display_name":"Transcription factor","level":3,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000070998","descriptor_name":"ATP Binding Cassette Transporter, Subfamily G, Member 1","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000071518","descriptor_name":"Liver X Receptors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000096926","descriptor_name":"Benzenesulfonamides","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001013","descriptor_name":"Aorta, Thoracic","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D001013","descriptor_name":"Aorta, Thoracic","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D001013","descriptor_name":"Aorta, Thoracic","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D001057","descriptor_name":"Apolipoproteins E","qualifier_ui":"Q000172","qualifier_name":"deficiency","is_major_topic":false},{"descriptor_ui":"D001057","descriptor_name":"Apolipoproteins E","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004730","descriptor_name":"Endothelium, Vascular","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D004730","descriptor_name":"Endothelium, Vascular","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D004730","descriptor_name":"Endothelium, Vascular","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D005466","descriptor_name":"Fluorocarbons","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006845","descriptor_name":"Hydrocarbons, Fluorinated","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D006845","descriptor_name":"Hydrocarbons, Fluorinated","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D008055","descriptor_name":"Lipids","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D008074","descriptor_name":"Lipoproteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008810","descriptor_name":"Mice, Inbred C57BL","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013449","descriptor_name":"Sulfonamides","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D013449","descriptor_name":"Sulfonamides","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D014661","descriptor_name":"Vasoconstriction","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D014664","descriptor_name":"Vasodilation","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D018345","descriptor_name":"Mice, Knockout","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018528","descriptor_name":"ATP-Binding Cassette Transporters","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D050197","descriptor_name":"Atherosclerosis","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D050197","descriptor_name":"Atherosclerosis","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D050197","descriptor_name":"Atherosclerosis","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D051058","descriptor_name":"Oncogene Protein v-akt","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D052250","descriptor_name":"Nitric Oxide Synthase Type III","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D057093","descriptor_name":"Orphan Nuclear Receptors","qualifier_ui":"Q000819","qualifier_name":"agonists","is_major_topic":true},{"descriptor_ui":"D058226","descriptor_name":"Plaque, Atherosclerotic","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D058226","descriptor_name":"Plaque, Atherosclerotic","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D058226","descriptor_name":"Plaque, Atherosclerotic","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D064286","descriptor_name":"ATP Binding Cassette Transporter 1","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1007/s00011-012-0529-4","doi":"https://doi.org/10.1007/s00011-012-0529-4","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s00011-012-0529-4","pdf_url":null,"source":{"id":"https://openalex.org/S55943811","display_name":"Inflammation Research","issn_l":"1023-3830","issn":["1023-3830","1420-908X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Inflammation Research","raw_type":"journal-article"},{"id":"pmid:22833121","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22833121","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Inflammation research : official journal of the European Histamine Research Society ... [et al.]","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":30,"referenced_works":["https://openalex.org/W326686267","https://openalex.org/W1860908381","https://openalex.org/W1966920769","https://openalex.org/W1979674730","https://openalex.org/W1986524045","https://openalex.org/W1990800912","https://openalex.org/W1996263427","https://openalex.org/W1996457468","https://openalex.org/W2007363852","https://openalex.org/W2026587556","https://openalex.org/W2036087773","https://openalex.org/W2043805010","https://openalex.org/W2046907879","https://openalex.org/W2059526592","https://openalex.org/W2075252151","https://openalex.org/W2081919183","https://openalex.org/W2108823809","https://openalex.org/W2109855608","https://openalex.org/W2111733232","https://openalex.org/W2112632255","https://openalex.org/W2115955355","https://openalex.org/W2119344085","https://openalex.org/W2135806933","https://openalex.org/W2146864851","https://openalex.org/W2153673003","https://openalex.org/W2159332620","https://openalex.org/W2168019510","https://openalex.org/W2178902387","https://openalex.org/W2340104535","https://openalex.org/W4230088158"],"related_works":["https://openalex.org/W2059526592","https://openalex.org/W2369412515","https://openalex.org/W2030806403","https://openalex.org/W2021996396","https://openalex.org/W1978810982","https://openalex.org/W1996635841","https://openalex.org/W2026587556","https://openalex.org/W2373587963","https://openalex.org/W3007996048","https://openalex.org/W2160015677"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":5},{"year":2013,"cited_by_count":1}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}