{"id":"https://openalex.org/W2105769864","doi":"https://doi.org/10.1016/0002-9343(92)90574-u","title":"Response of latent syphilis or neurosyphilis to ceftriaxone therapy in persons infected with human immunodeficiency virus","display_name":"Response of latent syphilis or neurosyphilis to ceftriaxone therapy in persons infected with human immunodeficiency virus","publication_year":1992,"publication_date":"1992-11-01","ids":{"openalex":"https://openalex.org/W2105769864","doi":"https://doi.org/10.1016/0002-9343(92)90574-u","mag":"2105769864","pmid":"https://pubmed.ncbi.nlm.nih.gov/1442850"},"language":"en","primary_location":{"id":"doi:10.1016/0002-9343(92)90574-u","doi":"https://doi.org/10.1016/0002-9343(92)90574-u","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0002-9343(92)90574-u","pdf_url":null,"source":{"id":"https://openalex.org/S186920367","display_name":"The American Journal of Medicine","issn_l":"0002-9343","issn":["0002-9343","1555-7162"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American Journal of Medicine","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5057535003","display_name":"Mark E. Dowell","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1322918889","display_name":"United States Department of Veterans Affairs","ror":"https://ror.org/05rsv9s98","country_code":"US","type":"government","lineage":["https://openalex.org/I1322918889"]},{"id":"https://openalex.org/I181547552","display_name":"Baylor College of Medicine","ror":"https://ror.org/02pttbw34","country_code":"US","type":"education","lineage":["https://openalex.org/I181547552","https://openalex.org/I2801539370"]},{"id":"https://openalex.org/I2799886695","display_name":"Veterans Health Administration","ror":"https://ror.org/05eq41471","country_code":"US","type":"government","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mark E. Dowell","raw_affiliation_strings":["Infectious Disease Section, Veterans Affairs Medical Center, Houston, Texas 77030","Baylor College of Medicine, Houston, Texas, USA","Infectious Disease Section and the Syphilis Research Laboratory, Veterans Affairs Medical Center Houston, Texas, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Infectious Disease Section, Veterans Affairs Medical Center, Houston, Texas 77030","institution_ids":["https://openalex.org/I2799886695"]},{"raw_affiliation_string":"Baylor College of Medicine, Houston, Texas, USA","institution_ids":["https://openalex.org/I181547552"]},{"raw_affiliation_string":"Infectious Disease Section and the Syphilis Research Laboratory, Veterans Affairs Medical Center Houston, Texas, USA","institution_ids":["https://openalex.org/I1322918889","https://openalex.org/I2799886695"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086176162","display_name":"Paul G. Ross","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2801539370","display_name":"Harris Health System","ror":"https://ror.org/04m8z4n60","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2801539370"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Paul G. Ross","raw_affiliation_strings":["The Thomas Street Clinic of the Harris County Medical District Houston, Texas, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Thomas Street Clinic of the Harris County Medical District Houston, Texas, USA","institution_ids":["https://openalex.org/I2801539370"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033234911","display_name":"Daniel M. Musher","orcid":"https://orcid.org/0000-0002-7571-066X","observed_orcids":["https://orcid.org/0000-0002-7571-066X"]},"institutions":[{"id":"https://openalex.org/I1322918889","display_name":"United States Department of Veterans Affairs","ror":"https://ror.org/05rsv9s98","country_code":"US","type":"government","lineage":["https://openalex.org/I1322918889"]},{"id":"https://openalex.org/I181547552","display_name":"Baylor College of Medicine","ror":"https://ror.org/02pttbw34","country_code":"US","type":"education","lineage":["https://openalex.org/I181547552","https://openalex.org/I2801539370"]},{"id":"https://openalex.org/I2799886695","display_name":"Veterans Health Administration","ror":"https://ror.org/05eq41471","country_code":"US","type":"government","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Daniel M. Musher","raw_affiliation_strings":["Baylor College of Medicine, Houston, Texas, USA","Infectious Disease Section and the Syphilis Research Laboratory, Veterans Affairs Medical Center Houston, Texas, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Baylor College of Medicine, Houston, Texas, USA","institution_ids":["https://openalex.org/I181547552"]},{"raw_affiliation_string":"Infectious Disease Section and the Syphilis Research Laboratory, Veterans Affairs Medical Center Houston, Texas, USA","institution_ids":["https://openalex.org/I1322918889","https://openalex.org/I2799886695"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110900252","display_name":"Thomas R. Cate","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I181547552","display_name":"Baylor College of Medicine","ror":"https://ror.org/02pttbw34","country_code":"US","type":"education","lineage":["https://openalex.org/I181547552","https://openalex.org/I2801539370"]},{"id":"https://openalex.org/I2801539370","display_name":"Harris Health System","ror":"https://ror.org/04m8z4n60","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2801539370"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Thomas R. Cate","raw_affiliation_strings":["Baylor College of Medicine, Houston, Texas, USA","The Thomas Street Clinic of the Harris County Medical District Houston, Texas, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Baylor College of Medicine, Houston, Texas, USA","institution_ids":["https://openalex.org/I181547552"]},{"raw_affiliation_string":"The Thomas Street Clinic of the Harris County Medical District Houston, Texas, USA","institution_ids":["https://openalex.org/I2801539370"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5108375643","display_name":"ROBERT E. BAUGHN","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1322918889","display_name":"United States Department of Veterans Affairs","ror":"https://ror.org/05rsv9s98","country_code":"US","type":"government","lineage":["https://openalex.org/I1322918889"]},{"id":"https://openalex.org/I181547552","display_name":"Baylor College of Medicine","ror":"https://ror.org/02pttbw34","country_code":"US","type":"education","lineage":["https://openalex.org/I181547552","https://openalex.org/I2801539370"]},{"id":"https://openalex.org/I2799886695","display_name":"Veterans Health Administration","ror":"https://ror.org/05eq41471","country_code":"US","type":"government","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert E. Baughn","raw_affiliation_strings":["Baylor College of Medicine, Houston, Texas, USA","Infectious Disease Section and the Syphilis Research Laboratory, Veterans Affairs Medical Center Houston, Texas, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Baylor College of Medicine, Houston, Texas, USA","institution_ids":["https://openalex.org/I181547552"]},{"raw_affiliation_string":"Infectious Disease Section and the Syphilis Research Laboratory, Veterans Affairs Medical Center Houston, Texas, USA","institution_ids":["https://openalex.org/I1322918889","https://openalex.org/I2799886695"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5033234911"],"corresponding_institution_ids":["https://openalex.org/I1322918889","https://openalex.org/I181547552","https://openalex.org/I2799886695"],"apc_list":{"value":3770,"currency":"USD","value_usd":3770},"apc_paid":null,"fwci":4.8539,"has_fulltext":false,"cited_by_count":129,"citation_normalized_percentile":{"value":0.95184621,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"93","issue":"5","first_page":"481","last_page":"488"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11934","display_name":"Syphilis Diagnosis and Treatment","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11934","display_name":"Syphilis Diagnosis and Treatment","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T14275","display_name":"Historical Medical Research and Treatments","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11381","display_name":"Infectious Diseases and Tuberculosis","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ceftriaxone","display_name":"ceftriaxone","score":0.8920000195503235},{"id":"https://openalex.org/keywords/latent-syphilis","display_name":"latent syphilis","score":0.9810000061988831},{"id":"https://openalex.org/keywords/neurosyphilis","display_name":"neurosyphilis","score":0.8980000019073486},{"id":"https://openalex.org/keywords/hiv-infection","display_name":"HIV infection","score":0.890999972820282},{"id":"https://openalex.org/keywords/benzathine-penicillin","display_name":"benzathine penicillin","score":0.9160000085830688},{"id":"https://openalex.org/keywords/treatment-response","display_name":"treatment response","score":0.6299999952316284},{"id":"https://openalex.org/keywords/cd4-count","display_name":"CD4 count","score":0.7749999761581421},{"id":"https://openalex.org/keywords/cerebrospinal-fluid","display_name":"cerebrospinal fluid","score":0.7360000014305115},{"id":"https://openalex.org/keywords/syphilis-screening","display_name":"syphilis screening","score":0.5059999823570251},{"id":"https://openalex.org/keywords/treatment-failure","display_name":"treatment failure","score":0.4189999997615814},{"id":"https://openalex.org/keywords/hiv-associated-neurosyphilis","display_name":"HIV-associated neurosyphilis","score":0.4650000035762787},{"id":"https://openalex.org/keywords/vdrl-serology","display_name":"VDRL serology","score":0.5730000138282776},{"id":"https://openalex.org/keywords/lumbar-puncture","display_name":"lumbar puncture","score":0.6499999761581421},{"id":"https://openalex.org/keywords/treatment-duration","display_name":"treatment duration","score":0.32199999690055847},{"id":"https://openalex.org/keywords/benzathine","display_name":"benzathine","score":0.45899999141693115}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9738710522651672},{"id":"https://openalex.org/C2781319584","wikidata":"https://www.wikidata.org/wiki/Q7888578","display_name":"Neurosyphilis","level":4,"score":0.9014033079147339},{"id":"https://openalex.org/C2776520383","wikidata":"https://www.wikidata.org/wiki/Q421713","display_name":"Ceftriaxone","level":3,"score":0.8130747079849243},{"id":"https://openalex.org/C2776983459","wikidata":"https://www.wikidata.org/wiki/Q41083","display_name":"Syphilis","level":3,"score":0.7801178693771362},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.5785877108573914},{"id":"https://openalex.org/C3013748606","wikidata":"https://www.wikidata.org/wiki/Q15787","display_name":"Human immunodeficiency virus (HIV)","level":2,"score":0.5454840660095215},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.42626142501831055},{"id":"https://openalex.org/C501593827","wikidata":"https://www.wikidata.org/wiki/Q12187","display_name":"Antibiotics","level":2,"score":0.21926695108413696},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.08805704116821289},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002443","descriptor_name":"Ceftriaxone","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009494","descriptor_name":"Neurosyphilis","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D009494","descriptor_name":"Neurosyphilis","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D009494","descriptor_name":"Neurosyphilis","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D010401","descriptor_name":"Penicillin G Benzathine","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D013588","descriptor_name":"Syphilis Serodiagnosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013592","descriptor_name":"Syphilis, Latent","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D013592","descriptor_name":"Syphilis, Latent","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D013592","descriptor_name":"Syphilis, Latent","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/0002-9343(92)90574-u","doi":"https://doi.org/10.1016/0002-9343(92)90574-u","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0002-9343(92)90574-u","pdf_url":null,"source":{"id":"https://openalex.org/S186920367","display_name":"The American Journal of Medicine","issn_l":"0002-9343","issn":["0002-9343","1555-7162"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American Journal of Medicine","raw_type":"journal-article"},{"id":"pmid:1442850","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1442850","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American journal of medicine","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":56,"referenced_works":["https://openalex.org/W91604092","https://openalex.org/W948813433","https://openalex.org/W1598409743","https://openalex.org/W1599394302","https://openalex.org/W1833207062","https://openalex.org/W1970843824","https://openalex.org/W1973567284","https://openalex.org/W1979052204","https://openalex.org/W1985490269","https://openalex.org/W1988917007","https://openalex.org/W1990798314","https://openalex.org/W1991693687","https://openalex.org/W1993034558","https://openalex.org/W1993600579","https://openalex.org/W2007404003","https://openalex.org/W2007435037","https://openalex.org/W2013970703","https://openalex.org/W2019651984","https://openalex.org/W2023234240","https://openalex.org/W2026173561","https://openalex.org/W2039033109","https://openalex.org/W2053057103","https://openalex.org/W2053980330","https://openalex.org/W2056330847","https://openalex.org/W2057877183","https://openalex.org/W2059068497","https://openalex.org/W2061964917","https://openalex.org/W2064108494","https://openalex.org/W2064975309","https://openalex.org/W2071000306","https://openalex.org/W2071759463","https://openalex.org/W2075352426","https://openalex.org/W2079059511","https://openalex.org/W2099891923","https://openalex.org/W2130355588","https://openalex.org/W2132855724","https://openalex.org/W2136440312","https://openalex.org/W2142870332","https://openalex.org/W2145251415","https://openalex.org/W2145642064","https://openalex.org/W2167964088","https://openalex.org/W2169350771","https://openalex.org/W2232250499","https://openalex.org/W2315065641","https://openalex.org/W2316392967","https://openalex.org/W2320103161","https://openalex.org/W2330788102","https://openalex.org/W2399001425","https://openalex.org/W2401654393","https://openalex.org/W2408748158","https://openalex.org/W2418938475","https://openalex.org/W4206800441","https://openalex.org/W4245126352","https://openalex.org/W4299576523","https://openalex.org/W6648566737","https://openalex.org/W6724406648"],"related_works":["https://openalex.org/W2139553095","https://openalex.org/W2025120726","https://openalex.org/W2323588299","https://openalex.org/W2903523424","https://openalex.org/W4415147576","https://openalex.org/W2019956301","https://openalex.org/W2070714605","https://openalex.org/W2038198113","https://openalex.org/W2093379777","https://openalex.org/W2144107718"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":7},{"year":2020,"cited_by_count":3},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":9},{"year":2014,"cited_by_count":8},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2016-06-24T00:00:00"}