{"id":"https://openalex.org/W2104871682","doi":"https://doi.org/10.1084/jem.152.1.41","title":"Studies of the antibody-dependent killing of schistosomula of Schistosoma mansoni employing haptenic target antigens. I. Evidence that the loss in susceptibility to immune damage undergone by developing schistosomula involves a change unrelated to the masking of parasite antigens by host molecules.","display_name":"Studies of the antibody-dependent killing of schistosomula of Schistosoma mansoni employing haptenic target antigens. I. Evidence that the loss in susceptibility to immune damage undergone by developing schistosomula involves a change unrelated to the masking of parasite antigens by host molecules.","publication_year":1980,"publication_date":"1980-07-01","ids":{"openalex":"https://openalex.org/W2104871682","doi":"https://doi.org/10.1084/jem.152.1.41","mag":"2104871682","pmid":"https://pubmed.ncbi.nlm.nih.gov/7400756","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2185897"},"language":"en","primary_location":{"id":"doi:10.1084/jem.152.1.41","doi":"https://doi.org/10.1084/jem.152.1.41","is_oa":true,"landing_page_url":"https://doi.org/10.1084/jem.152.1.41","pdf_url":"https://rupress.org/jem/article-pdf/152/1/41/1090950/41.pdf","source":{"id":"https://openalex.org/S22947807","display_name":"The Journal of Experimental Medicine","issn_l":"0022-1007","issn":["0022-1007","1540-9538"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315676","host_organization_name":"Rockefeller University Press","host_organization_lineage":["https://openalex.org/P4310315676"],"host_organization_lineage_names":["Rockefeller University Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of experimental medicine","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://rupress.org/jem/article-pdf/152/1/41/1090950/41.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5090947528","display_name":"G Moser","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"G Moser","raw_affiliation_strings":["From the Departments of Medicine and Pathology , Harvard Medical School and the Robert B. Brigham Division of the","From the Departments of Medicine and Pathology, Harvard Medical School and the Robert B. Brigham Division of the Affiliated Hospitals Center, Inc., Boston, Massachusetts 02115;","the Department of Medicine and Immunology, Mayo Foundation, Rochester, Minnesota 55901"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Departments of Medicine and Pathology , Harvard Medical School and the Robert B. Brigham Division of the","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"From the Departments of Medicine and Pathology, Harvard Medical School and the Robert B. Brigham Division of the Affiliated Hospitals Center, Inc., Boston, Massachusetts 02115;","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"the Department of Medicine and Immunology, Mayo Foundation, Rochester, Minnesota 55901","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024094839","display_name":"Donald L. Wassom","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"D L Wassom","raw_affiliation_strings":["Affiliated Hospitals Center, Inc. , Boston , Massachusetts 02115 ; and the Department of Medicine and Immunology ,","From the Departments of Medicine and Pathology , Harvard Medical School and the Robert B. Brigham Division of the","From the Departments of Medicine and Pathology, Harvard Medical School and the Robert B. Brigham Division of the Affiliated Hospitals Center, Inc., Boston, Massachusetts 02115;","the Department of Medicine and Immunology, Mayo Foundation, Rochester, Minnesota 55901"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Affiliated Hospitals Center, Inc. , Boston , Massachusetts 02115 ; and the Department of Medicine and Immunology ,","institution_ids":[]},{"raw_affiliation_string":"From the Departments of Medicine and Pathology , Harvard Medical School and the Robert B. Brigham Division of the","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"From the Departments of Medicine and Pathology, Harvard Medical School and the Robert B. Brigham Division of the Affiliated Hospitals Center, Inc., Boston, Massachusetts 02115;","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"the Department of Medicine and Immunology, Mayo Foundation, Rochester, Minnesota 55901","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5016487212","display_name":"Alan Sher","orcid":"https://orcid.org/0000-0001-7053-2895","observed_orcids":["https://orcid.org/0000-0001-7053-2895"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"A Sher","raw_affiliation_strings":["Mayo Foundation , Rochester , Minnesota 55901","From the Departments of Medicine and Pathology, Harvard Medical School and the Robert B. Brigham Division of the Affiliated Hospitals Center, Inc., Boston, Massachusetts 02115;","the Department of Medicine and Immunology, Mayo Foundation, Rochester, Minnesota 55901"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Mayo Foundation , Rochester , Minnesota 55901","institution_ids":["https://openalex.org/I1330342723"]},{"raw_affiliation_string":"From the Departments of Medicine and Pathology, Harvard Medical School and the Robert B. Brigham Division of the Affiliated Hospitals Center, Inc., Boston, Massachusetts 02115;","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"the Department of Medicine and Immunology, Mayo Foundation, Rochester, Minnesota 55901","institution_ids":["https://openalex.org/I1330342723"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":10.2507,"has_fulltext":true,"cited_by_count":59,"citation_normalized_percentile":{"value":0.98591549,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":94},"biblio":{"volume":"152","issue":"1","first_page":"41","last_page":"53"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10695","display_name":"Parasites and Host Interactions","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2405","display_name":"Parasitology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10695","display_name":"Parasites and Host Interactions","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2405","display_name":"Parasitology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12234","display_name":"Mollusks and Parasites Studies","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1109","display_name":"Insect Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11403","display_name":"Invertebrate Immune Response Mechanisms","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/schistosoma-mansoni","display_name":"Schistosoma mansoni","score":0.9959999918937683},{"id":"https://openalex.org/keywords/schistosomula","display_name":"schistosomula","score":0.9169999957084656},{"id":"https://openalex.org/keywords/antibody-dependent-cellular-cytotoxicity","display_name":"antibody-dependent cellular cytotoxicity","score":0.8600000143051147},{"id":"https://openalex.org/keywords/complement-mediated-killing","display_name":"complement-mediated killing","score":0.7039999961853027},{"id":"https://openalex.org/keywords/eosinophils","display_name":"eosinophils","score":0.9359999895095825},{"id":"https://openalex.org/keywords/immune-evasion","display_name":"immune evasion","score":0.6100000143051147},{"id":"https://openalex.org/keywords/antigen-masking","display_name":"antigen masking","score":0.843999981880188},{"id":"https://openalex.org/keywords/larval-development","display_name":"larval development","score":0.5199999809265137},{"id":"https://openalex.org/keywords/host-parasite-interactions","display_name":"host-parasite interactions","score":0.6200000047683716},{"id":"https://openalex.org/keywords/anti-tnp-antibodies","display_name":"anti-TNP antibodies","score":0.527999997138977}],"concepts":[{"id":"https://openalex.org/C2776863245","wikidata":"https://www.wikidata.org/wiki/Q2324689","display_name":"Schistosoma mansoni","level":4,"score":0.8827807903289795},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7812554836273193},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.6552267670631409},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.6469859480857849},{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.6193891763687134},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.5737457871437073},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.548195481300354},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.4751453399658203},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.35821032524108887},{"id":"https://openalex.org/C2776225656","wikidata":"https://www.wikidata.org/wiki/Q221159","display_name":"Schistosomiasis","level":3,"score":0.1971077024936676},{"id":"https://openalex.org/C165901193","wikidata":"https://www.wikidata.org/wiki/Q3129936","display_name":"Helminths","level":2,"score":0.1434701383113861},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.07942354679107666},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000920","descriptor_name":"Antibody-Dependent Cell Cytotoxicity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000941","descriptor_name":"Antigens","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D003165","descriptor_name":"Complement System Proteins","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D004804","descriptor_name":"Eosinophils","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006241","descriptor_name":"Haptens","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D007114","descriptor_name":"Immunization","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008168","descriptor_name":"Lung","qualifier_ui":"Q000469","qualifier_name":"parasitology","is_major_topic":false},{"descriptor_ui":"D009578","descriptor_name":"Nitrobenzenes","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D012550","descriptor_name":"Schistosoma mansoni","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D012867","descriptor_name":"Skin","qualifier_ui":"Q000469","qualifier_name":"parasitology","is_major_topic":false},{"descriptor_ui":"D014301","descriptor_name":"Trinitrobenzenes","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1084/jem.152.1.41","doi":"https://doi.org/10.1084/jem.152.1.41","is_oa":true,"landing_page_url":"https://doi.org/10.1084/jem.152.1.41","pdf_url":"https://rupress.org/jem/article-pdf/152/1/41/1090950/41.pdf","source":{"id":"https://openalex.org/S22947807","display_name":"The Journal of Experimental Medicine","issn_l":"0022-1007","issn":["0022-1007","1540-9538"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315676","host_organization_name":"Rockefeller University Press","host_organization_lineage":["https://openalex.org/P4310315676"],"host_organization_lineage_names":["Rockefeller University Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of experimental medicine","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:2185897","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2185897","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Exp Med","raw_type":"Text"},{"id":"pmid:7400756","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/7400756","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of experimental medicine","raw_type":"Journal Article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.285.5238","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.285.5238","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/a6/21/J_Exp_Med_1980_Jul_1_152(1)_41-53.tar.gz","raw_type":"text"}],"best_oa_location":{"id":"doi:10.1084/jem.152.1.41","doi":"https://doi.org/10.1084/jem.152.1.41","is_oa":true,"landing_page_url":"https://doi.org/10.1084/jem.152.1.41","pdf_url":"https://rupress.org/jem/article-pdf/152/1/41/1090950/41.pdf","source":{"id":"https://openalex.org/S22947807","display_name":"The Journal of Experimental Medicine","issn_l":"0022-1007","issn":["0022-1007","1540-9538"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315676","host_organization_name":"Rockefeller University Press","host_organization_lineage":["https://openalex.org/P4310315676"],"host_organization_lineage_names":["Rockefeller University Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of experimental medicine","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.8048999905586243,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320306149","display_name":"Rockefeller Foundation","ror":"https://ror.org/03sfkwk85"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2104871682.pdf","grobid_xml":"https://content.openalex.org/works/W2104871682.grobid-xml"},"referenced_works_count":29,"referenced_works":["https://openalex.org/W7192042","https://openalex.org/W1513425511","https://openalex.org/W1537722281","https://openalex.org/W1544525315","https://openalex.org/W1549521886","https://openalex.org/W1551461025","https://openalex.org/W1554912114","https://openalex.org/W1577982459","https://openalex.org/W1589105822","https://openalex.org/W1839437408","https://openalex.org/W1846602472","https://openalex.org/W1964532737","https://openalex.org/W1974690528","https://openalex.org/W1997133987","https://openalex.org/W2026780245","https://openalex.org/W2033299582","https://openalex.org/W2065196424","https://openalex.org/W2067515857","https://openalex.org/W2085758614","https://openalex.org/W2092067692","https://openalex.org/W2095425835","https://openalex.org/W2099039056","https://openalex.org/W2127376452","https://openalex.org/W2145095193","https://openalex.org/W2150135081","https://openalex.org/W2151030698","https://openalex.org/W2157945936","https://openalex.org/W2301365634","https://openalex.org/W2401034493"],"related_works":["https://openalex.org/W7098987281","https://openalex.org/W2038204816","https://openalex.org/W1553671974","https://openalex.org/W1564834275","https://openalex.org/W2106526347","https://openalex.org/W1987730353","https://openalex.org/W1482593695","https://openalex.org/W1518585060","https://openalex.org/W2018238528","https://openalex.org/W1667168945"],"abstract_inverted_index":{"A":[0],"method":[1],"was":[2],"developed":[3],"for":[4,54,190],"coupling":[5],"a":[6,21,183],"hapten,":[7],"trinitrophenyl":[8],"(TNP),":[9],"to":[10,57,89,111,115,125,128,148],"the":[11,117,131,143,163,166,174],"surface":[12,46],"of":[13,15,145,165,176,185],"schistosomula":[14,45,147],"Schistosoma":[16],"mansoni":[17],"which":[18,106],"results":[19],"in":[20,24,32,38,48,65,68,76,100,133,136,155,162],"minimal":[22],"loss":[23],"their":[25,55],"viability":[26],"as":[27,120],"judged":[28],"by":[29,59,94,109,130,173,179],"morphological":[30],"examination":[31],"vitro":[33,137],"and":[34,42,67,85,135,168],"survival":[35],"after":[36],"injection":[37],"vivo.":[39],"Skin-stage":[40],"(3-h-old)":[41],"lung-stage":[43],"(5-d-old)":[44],"labeled":[47],"this":[49],"manner":[50],"were":[51,73,86,107,123],"then":[52],"compared":[53],"susceptibility":[56],"killing":[58,91,129,150],"anti-TNP":[60,113],"antibody-dependent":[61,149],"effector":[62],"mechanisms":[63],"both":[64],"vivo":[66,134],"vitro.":[69,101],"TNP":[70,81],"skin-stage":[71,121],"larvae":[72],"readily":[74],"rejected":[75],"mice":[77],"actively":[78],"immunized":[79],"against":[80],"bovine":[82],"gamma":[83],"globulin":[84],"highly":[87],"susceptible":[88],"anti-TNP-dependent":[90],"mediated":[92],"either":[93],"complement":[95],"or":[96],"purified":[97],"human":[98],"eosinophils":[99],"In":[102],"contrast,":[103],"TNP-lung-stage":[104],"schistosomula,":[105,122],"shown":[108],"microfluorimetry":[110],"bind":[112],"antibody":[114],"approximately":[116],"same":[118,132],"extent":[119],"found":[124],"be":[126,170],"resistant":[127],"mechanisms.":[138],"These":[139],"findings":[140],"suggest":[141],"that":[142],"insusceptibility":[144],"postskin-stage":[146],"must":[151],"result":[152],"at":[153],"least":[154],"part":[156],"from":[157],"an":[158],"intrinsic":[159],"structural":[160],"change":[161],"integument":[164],"parasite":[167,177],"cannot":[169],"caused":[171],"solely":[172],"masking":[175],"antigens":[178],"acquired":[180],"host":[181],"molecules,":[182],"mechanism":[184],"immune":[186],"evasion":[187],"previously":[188],"proposed":[189],"schistosomes.":[191]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}