{"id":"https://openalex.org/W2104697158","doi":"https://doi.org/10.1002/chem.201503253","title":"Intramolecular OH\u22c5\u22c5\u22c5Fluorine Hydrogen Bonding in Saturated, Acyclic Fluorohydrins: The \u03b3\u2010Fluoropropanol Motif","display_name":"Intramolecular OH\u22c5\u22c5\u22c5Fluorine Hydrogen Bonding in Saturated, Acyclic Fluorohydrins: The \u03b3\u2010Fluoropropanol Motif","publication_year":2015,"publication_date":"2015-10-23","ids":{"openalex":"https://openalex.org/W2104697158","doi":"https://doi.org/10.1002/chem.201503253","mag":"2104697158","pmid":"https://pubmed.ncbi.nlm.nih.gov/26494542","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4676915"},"language":"en","primary_location":{"id":"doi:10.1002/chem.201503253","doi":"https://doi.org/10.1002/chem.201503253","is_oa":true,"landing_page_url":"https://doi.org/10.1002/chem.201503253","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/chem.201503253","source":{"id":"https://openalex.org/S68911691","display_name":"Chemistry - A European Journal","issn_l":"0947-6539","issn":["0947-6539","1521-3765"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chemistry \u2013 A European Journal","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/chem.201503253","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5024989967","display_name":"Bruno Linclau","orcid":"https://orcid.org/0000-0001-8762-0170","observed_orcids":["https://orcid.org/0000-0001-8762-0170"]},"institutions":[{"id":"https://openalex.org/I43439940","display_name":"University of Southampton","ror":"https://ror.org/01ryk1543","country_code":"GB","type":"education","lineage":["https://openalex.org/I43439940"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Bruno Linclau","raw_affiliation_strings":["Department of Chemistry, University of Southampton, Highfield, Southampton SO17 1BJ (UK), Fax: (+44)\u200923-8059-6805. bruno.linclau@soton.ac.uk","School of Chemistry [Southampton, UK] (University of Southampton Southampton, Hants, SO17 1BJ, United Kingdom - United Kingdom)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, University of Southampton, Highfield, Southampton SO17 1BJ (UK), Fax: (+44)\u200923-8059-6805. bruno.linclau@soton.ac.uk","institution_ids":["https://openalex.org/I43439940"]},{"raw_affiliation_string":"School of Chemistry [Southampton, UK] (University of Southampton Southampton, Hants, SO17 1BJ, United Kingdom - United Kingdom)","institution_ids":["https://openalex.org/I43439940"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087843917","display_name":"Florent P\u00e9ron","orcid":"https://orcid.org/0000-0002-5146-3182","observed_orcids":["https://orcid.org/0000-0002-5146-3182"]},"institutions":[{"id":"https://openalex.org/I43439940","display_name":"University of Southampton","ror":"https://ror.org/01ryk1543","country_code":"GB","type":"education","lineage":["https://openalex.org/I43439940"]},{"id":"https://openalex.org/I4392021217","display_name":"Centre d'Etudes et de Recherche sur le M\u00e9dicament de Normandie","ror":"https://ror.org/012jsqx30","country_code":"FR","type":"facility","lineage":["https://openalex.org/I4210105918","https://openalex.org/I4392021217","https://openalex.org/I98702875"]}],"countries":["FR","GB"],"is_corresponding":false,"raw_author_name":"Florent Peron","raw_affiliation_strings":["Department of Chemistry, University of Southampton, Highfield, Southampton SO17 1BJ (UK), Fax: (+44)\u200923-8059-6805","CERMN - Centre d'Etudes et de Recherche sur le M\u00e9dicament de Normandie (Boulevard Becquerel 14032 Caen cedex - France)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, University of Southampton, Highfield, Southampton SO17 1BJ (UK), Fax: (+44)\u200923-8059-6805","institution_ids":["https://openalex.org/I43439940"]},{"raw_affiliation_string":"CERMN - Centre d'Etudes et de Recherche sur le M\u00e9dicament de Normandie (Boulevard Becquerel 14032 Caen cedex - France)","institution_ids":["https://openalex.org/I4392021217"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059350133","display_name":"Elena Bogdan","orcid":"https://orcid.org/0000-0003-2282-3350","observed_orcids":["https://orcid.org/0000-0003-2282-3350","https://orcid.org/0000-0002-8196-1123"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I4210138474","display_name":"Chimie et Interdisciplinarit\u00e9, Synth\u00e8se, Analyse, Mod\u00e9lisation","ror":"https://ror.org/04ysg2a58","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I4210128300","https://openalex.org/I4210138474","https://openalex.org/I97188460"]},{"id":"https://openalex.org/I4405260337","display_name":"Universit\u00e9 de Nantes","ror":"https://ror.org/03kjmz544","country_code":"FR","type":"education","lineage":["https://openalex.org/I4405260337","https://openalex.org/I97188460"]},{"id":"https://openalex.org/I97188460","display_name":"Nantes Universit\u00e9","ror":"https://ror.org/03gnr7b55","country_code":"FR","type":"education","lineage":["https://openalex.org/I97188460"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Elena Bogdan","raw_affiliation_strings":["CEISAM UMR CNRS 6230, Facult\u00e9 des Sciences et des Techniques, Universit\u00e9 de Nantes, 2, rue de la Houssini\u00e8re - BP 92208, 44322 NANTES Cedex 3 (France), Fax: (+3)\u20092-51-12-54-02","CEISAM - Chimie Et Interdisciplinarit\u00e9 : Synth\u00e8se, Analyse, Mod\u00e9lisation (UFR des Sciences et des Techniques - 2 rue de la Houssiniere BP 92208 - 44322 NANTES Cedex 3 - France)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CEISAM UMR CNRS 6230, Facult\u00e9 des Sciences et des Techniques, Universit\u00e9 de Nantes, 2, rue de la Houssini\u00e8re - BP 92208, 44322 NANTES Cedex 3 (France), Fax: (+3)\u20092-51-12-54-02","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I4210138474","https://openalex.org/I4405260337","https://openalex.org/I97188460"]},{"raw_affiliation_string":"CEISAM - Chimie Et Interdisciplinarit\u00e9 : Synth\u00e8se, Analyse, Mod\u00e9lisation (UFR des Sciences et des Techniques - 2 rue de la Houssiniere BP 92208 - 44322 NANTES Cedex 3 - France)","institution_ids":["https://openalex.org/I4210138474","https://openalex.org/I97188460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035854377","display_name":"Neil J. Wells","orcid":"https://orcid.org/0000-0002-4607-5791","observed_orcids":["https://orcid.org/0000-0002-4607-5791"]},"institutions":[{"id":"https://openalex.org/I43439940","display_name":"University of Southampton","ror":"https://ror.org/01ryk1543","country_code":"GB","type":"education","lineage":["https://openalex.org/I43439940"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Neil Wells","raw_affiliation_strings":["Department of Chemistry, University of Southampton, Highfield, Southampton SO17 1BJ (UK), Fax: (+44)\u200923-8059-6805","University of Southampton (University Road, Southampton SO17 1BJ - United Kingdom)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, University of Southampton, Highfield, Southampton SO17 1BJ (UK), Fax: (+44)\u200923-8059-6805","institution_ids":["https://openalex.org/I43439940"]},{"raw_affiliation_string":"University of Southampton (University Road, Southampton SO17 1BJ - United Kingdom)","institution_ids":["https://openalex.org/I43439940"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076419989","display_name":"Zhong Wang","orcid":"https://orcid.org/0000-0002-6144-4022","observed_orcids":["https://orcid.org/0000-0002-6144-4022"]},"institutions":[{"id":"https://openalex.org/I43439940","display_name":"University of Southampton","ror":"https://ror.org/01ryk1543","country_code":"GB","type":"education","lineage":["https://openalex.org/I43439940"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Zhong Wang","raw_affiliation_strings":["Department of Chemistry, University of Southampton, Highfield, Southampton SO17 1BJ (UK), Fax: (+44)\u200923-8059-6805","School of Chemistry [Southampton, UK] (University of Southampton Southampton, Hants, SO17 1BJ, United Kingdom - United Kingdom)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, University of Southampton, Highfield, Southampton SO17 1BJ (UK), Fax: (+44)\u200923-8059-6805","institution_ids":["https://openalex.org/I43439940"]},{"raw_affiliation_string":"School of Chemistry [Southampton, UK] (University of Southampton Southampton, Hants, SO17 1BJ, United Kingdom - United Kingdom)","institution_ids":["https://openalex.org/I43439940"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065545390","display_name":"Guillaume Compain","orcid":"https://orcid.org/0000-0002-9556-1016","observed_orcids":["https://orcid.org/0000-0002-9556-1016"]},"institutions":[{"id":"https://openalex.org/I32881790","display_name":"Universit\u00e9 de Poitiers","ror":"https://ror.org/04xhy8q59","country_code":"FR","type":"education","lineage":["https://openalex.org/I32881790"]},{"id":"https://openalex.org/I4210087837","display_name":"Institut de Chimie des Milieux et des Mat\u00e9riaux de Poitiers","ror":"https://ror.org/001n7ee52","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I32881790","https://openalex.org/I4210087837","https://openalex.org/I4210128300"]},{"id":"https://openalex.org/I43439940","display_name":"University of Southampton","ror":"https://ror.org/01ryk1543","country_code":"GB","type":"education","lineage":["https://openalex.org/I43439940"]}],"countries":["FR","GB"],"is_corresponding":false,"raw_author_name":"Guillaume Compain","raw_affiliation_strings":["Department of Chemistry, University of Southampton, Highfield, Southampton SO17 1BJ (UK), Fax: (+44)\u200923-8059-6805","IC2MP [Poitiers] - Institut de chimie des milieux et mat\u00e9riaux de Poitiers [UMR 7285] (Universit\u00e9 de Poitiers \u2013 4 rue Michel brunet \u2013 B\u00e2timent B27 \u2013 TSA 51106 \u2013 86073 Poitiers Cedex 9 \u2013 France - France)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, University of Southampton, Highfield, Southampton SO17 1BJ (UK), Fax: (+44)\u200923-8059-6805","institution_ids":["https://openalex.org/I43439940"]},{"raw_affiliation_string":"IC2MP [Poitiers] - Institut de chimie des milieux et mat\u00e9riaux de Poitiers [UMR 7285] (Universit\u00e9 de Poitiers \u2013 4 rue Michel brunet \u2013 B\u00e2timent B27 \u2013 TSA 51106 \u2013 86073 Poitiers Cedex 9 \u2013 France - France)","institution_ids":["https://openalex.org/I32881790","https://openalex.org/I4210087837"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021927236","display_name":"Cl\u00e9ment Q. Fontenelle","orcid":"https://orcid.org/0000-0002-1630-3407","observed_orcids":["https://orcid.org/0000-0002-1630-3407"]},"institutions":[{"id":"https://openalex.org/I43439940","display_name":"University of Southampton","ror":"https://ror.org/01ryk1543","country_code":"GB","type":"education","lineage":["https://openalex.org/I43439940"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Clement Q. Fontenelle","raw_affiliation_strings":["Department of Chemistry, University of Southampton, Highfield, Southampton SO17 1BJ (UK), Fax: (+44)\u200923-8059-6805","University of Southampton (University Road, Southampton SO17 1BJ - United Kingdom)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, University of Southampton, Highfield, Southampton SO17 1BJ (UK), Fax: (+44)\u200923-8059-6805","institution_ids":["https://openalex.org/I43439940"]},{"raw_affiliation_string":"University of Southampton (University Road, Southampton SO17 1BJ - United Kingdom)","institution_ids":["https://openalex.org/I43439940"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038967647","display_name":"Nicolas Galland","orcid":"https://orcid.org/0000-0001-5618-226X","observed_orcids":["https://orcid.org/0000-0001-5618-226X"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I4210138474","display_name":"Chimie et Interdisciplinarit\u00e9, Synth\u00e8se, Analyse, Mod\u00e9lisation","ror":"https://ror.org/04ysg2a58","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I4210128300","https://openalex.org/I4210138474","https://openalex.org/I97188460"]},{"id":"https://openalex.org/I4405260337","display_name":"Universit\u00e9 de Nantes","ror":"https://ror.org/03kjmz544","country_code":"FR","type":"education","lineage":["https://openalex.org/I4405260337","https://openalex.org/I97188460"]},{"id":"https://openalex.org/I97188460","display_name":"Nantes Universit\u00e9","ror":"https://ror.org/03gnr7b55","country_code":"FR","type":"education","lineage":["https://openalex.org/I97188460"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Nicolas Galland","raw_affiliation_strings":["CEISAM UMR CNRS 6230, Facult\u00e9 des Sciences et des Techniques, Universit\u00e9 de Nantes, 2, rue de la Houssini\u00e8re - BP 92208, 44322 NANTES Cedex 3 (France), Fax: (+3)\u20092-51-12-54-02","CEISAM - Chimie Et Interdisciplinarit\u00e9 : Synth\u00e8se, Analyse, Mod\u00e9lisation (UFR des Sciences et des Techniques - 2 rue de la Houssiniere BP 92208 - 44322 NANTES Cedex 3 - France)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CEISAM UMR CNRS 6230, Facult\u00e9 des Sciences et des Techniques, Universit\u00e9 de Nantes, 2, rue de la Houssini\u00e8re - BP 92208, 44322 NANTES Cedex 3 (France), Fax: (+3)\u20092-51-12-54-02","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I4210138474","https://openalex.org/I4405260337","https://openalex.org/I97188460"]},{"raw_affiliation_string":"CEISAM - Chimie Et Interdisciplinarit\u00e9 : Synth\u00e8se, Analyse, Mod\u00e9lisation (UFR des Sciences et des Techniques - 2 rue de la Houssiniere BP 92208 - 44322 NANTES Cedex 3 - France)","institution_ids":["https://openalex.org/I4210138474","https://openalex.org/I97188460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012378549","display_name":"Jean\u2010Yves Le Questel","orcid":"https://orcid.org/0000-0001-5307-2137","observed_orcids":["https://orcid.org/0000-0001-5307-2137"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I4210138474","display_name":"Chimie et Interdisciplinarit\u00e9, Synth\u00e8se, Analyse, Mod\u00e9lisation","ror":"https://ror.org/04ysg2a58","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I4210128300","https://openalex.org/I4210138474","https://openalex.org/I97188460"]},{"id":"https://openalex.org/I4405260337","display_name":"Universit\u00e9 de Nantes","ror":"https://ror.org/03kjmz544","country_code":"FR","type":"education","lineage":["https://openalex.org/I4405260337","https://openalex.org/I97188460"]},{"id":"https://openalex.org/I97188460","display_name":"Nantes Universit\u00e9","ror":"https://ror.org/03gnr7b55","country_code":"FR","type":"education","lineage":["https://openalex.org/I97188460"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Jean\u2010Yves Le\u2005Questel","raw_affiliation_strings":["CEISAM UMR CNRS 6230, Facult\u00e9 des Sciences et des Techniques, Universit\u00e9 de Nantes, 2, rue de la Houssini\u00e8re - BP 92208, 44322 NANTES Cedex 3 (France), Fax: (+3)\u20092-51-12-54-02","CEISAM - Chimie Et Interdisciplinarit\u00e9 : Synth\u00e8se, Analyse, Mod\u00e9lisation (UFR des Sciences et des Techniques - 2 rue de la Houssiniere BP 92208 - 44322 NANTES Cedex 3 - France)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CEISAM UMR CNRS 6230, Facult\u00e9 des Sciences et des Techniques, Universit\u00e9 de Nantes, 2, rue de la Houssini\u00e8re - BP 92208, 44322 NANTES Cedex 3 (France), Fax: (+3)\u20092-51-12-54-02","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I4210138474","https://openalex.org/I4405260337","https://openalex.org/I97188460"]},{"raw_affiliation_string":"CEISAM - Chimie Et Interdisciplinarit\u00e9 : Synth\u00e8se, Analyse, Mod\u00e9lisation (UFR des Sciences et des Techniques - 2 rue de la Houssiniere BP 92208 - 44322 NANTES Cedex 3 - France)","institution_ids":["https://openalex.org/I4210138474","https://openalex.org/I97188460"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5059573239","display_name":"J\u00e9r\u00f4me Graton","orcid":"https://orcid.org/0000-0002-1114-200X","observed_orcids":["https://orcid.org/0000-0002-1114-200X"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I4210138474","display_name":"Chimie et Interdisciplinarit\u00e9, Synth\u00e8se, Analyse, Mod\u00e9lisation","ror":"https://ror.org/04ysg2a58","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I4210128300","https://openalex.org/I4210138474","https://openalex.org/I97188460"]},{"id":"https://openalex.org/I4405260337","display_name":"Universit\u00e9 de Nantes","ror":"https://ror.org/03kjmz544","country_code":"FR","type":"education","lineage":["https://openalex.org/I4405260337","https://openalex.org/I97188460"]},{"id":"https://openalex.org/I97188460","display_name":"Nantes Universit\u00e9","ror":"https://ror.org/03gnr7b55","country_code":"FR","type":"education","lineage":["https://openalex.org/I97188460"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"J\u00e9r\u00f4me Graton","raw_affiliation_strings":["CEISAM UMR CNRS 6230, Facult\u00e9 des Sciences et des Techniques, Universit\u00e9 de Nantes, 2, rue de la Houssini\u00e8re - BP 92208, 44322 NANTES Cedex 3 (France), Fax: (+3)\u20092-51-12-54-02. jerome.graton@univ-nantes.fr","CEISAM - Chimie Et Interdisciplinarit\u00e9 : Synth\u00e8se, Analyse, Mod\u00e9lisation (UFR des Sciences et des Techniques - 2 rue de la Houssiniere BP 92208 - 44322 NANTES Cedex 3 - France)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CEISAM UMR CNRS 6230, Facult\u00e9 des Sciences et des Techniques, Universit\u00e9 de Nantes, 2, rue de la Houssini\u00e8re - BP 92208, 44322 NANTES Cedex 3 (France), Fax: (+3)\u20092-51-12-54-02. jerome.graton@univ-nantes.fr","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I4210138474","https://openalex.org/I4405260337","https://openalex.org/I97188460"]},{"raw_affiliation_string":"CEISAM - Chimie Et Interdisciplinarit\u00e9 : Synth\u00e8se, Analyse, Mod\u00e9lisation (UFR des Sciences et des Techniques - 2 rue de la Houssiniere BP 92208 - 44322 NANTES Cedex 3 - France)","institution_ids":["https://openalex.org/I4210138474","https://openalex.org/I97188460"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":8,"corresponding_author_ids":["https://openalex.org/A5024989967"],"corresponding_institution_ids":["https://openalex.org/I43439940"],"apc_list":{"value":4640,"currency":"USD","value_usd":4640},"apc_paid":{"value":4640,"currency":"USD","value_usd":4640},"fwci":2.7373,"has_fulltext":true,"cited_by_count":48,"citation_normalized_percentile":{"value":0.90720596,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"21","issue":"49","first_page":"17808","last_page":"17816"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10798","display_name":"Crystallography and molecular interactions","score":0.9804999828338623,"subfield":{"id":"https://openalex.org/subfields/1606","display_name":"Physical and Theoretical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10798","display_name":"Crystallography and molecular interactions","score":0.9804999828338623,"subfield":{"id":"https://openalex.org/subfields/1606","display_name":"Physical and Theoretical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12967","display_name":"Molecular Spectroscopy and Structure","score":0.0044999998062849045,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10947","display_name":"Fluorine in Organic Chemistry","score":0.0032999999821186066,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/intramolecular-hydrogen-bonding","display_name":"intramolecular hydrogen bonding","score":0.9190000295639038},{"id":"https://openalex.org/keywords/fluorohydrins","display_name":"fluorohydrins","score":0.9169999957084656},{"id":"https://openalex.org/keywords/conformational-analysis","display_name":"conformational analysis","score":0.6639999747276306},{"id":"https://openalex.org/keywords/relative-configuration","display_name":"relative configuration","score":0.7910000085830688},{"id":"https://openalex.org/keywords/aliphatic-alcohols","display_name":"aliphatic alcohols","score":0.8569999933242798},{"id":"https://openalex.org/keywords/quantum-chemical-calculations","display_name":"quantum chemical calculations","score":0.6430000066757202}],"concepts":[{"id":"https://openalex.org/C75079739","wikidata":"https://www.wikidata.org/wiki/Q1571801","display_name":"Intramolecular force","level":2,"score":0.8859364986419678},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.7679972648620605},{"id":"https://openalex.org/C506198293","wikidata":"https://www.wikidata.org/wiki/Q650","display_name":"Fluorine","level":2,"score":0.7597715258598328},{"id":"https://openalex.org/C112887158","wikidata":"https://www.wikidata.org/wiki/Q169324","display_name":"Hydrogen bond","level":3,"score":0.7476339340209961},{"id":"https://openalex.org/C2780263894","wikidata":"https://www.wikidata.org/wiki/Q335268","display_name":"Alkyl","level":2,"score":0.5729869604110718},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.5146516561508179},{"id":"https://openalex.org/C147597530","wikidata":"https://www.wikidata.org/wiki/Q369472","display_name":"Computational chemistry","level":1,"score":0.364651620388031},{"id":"https://openalex.org/C155647269","wikidata":"https://www.wikidata.org/wiki/Q243455","display_name":"Medicinal chemistry","level":1,"score":0.3247022032737732},{"id":"https://openalex.org/C32909587","wikidata":"https://www.wikidata.org/wiki/Q11369","display_name":"Molecule","level":2,"score":0.2776188850402832},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.20689186453819275}],"mesh":[],"locations_count":7,"locations":[{"id":"doi:10.1002/chem.201503253","doi":"https://doi.org/10.1002/chem.201503253","is_oa":true,"landing_page_url":"https://doi.org/10.1002/chem.201503253","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/chem.201503253","source":{"id":"https://openalex.org/S68911691","display_name":"Chemistry - A European Journal","issn_l":"0947-6539","issn":["0947-6539","1521-3765"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chemistry \u2013 A European Journal","raw_type":"journal-article"},{"id":"pmid:26494542","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/26494542","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chemistry (Weinheim an der Bergstrasse, Germany)","raw_type":"Journal Article"},{"id":"pmh:oai:archive.ugent.be:01GMMX8EEPN7ESEMFXPS1QGHFE","doi":null,"is_oa":false,"landing_page_url":"https://biblio.ugent.be/publication/01GMMX8EEPN7ESEMFXPS1QGHFE","pdf_url":null,"source":{"id":"https://openalex.org/S4306400478","display_name":"Ghent University Academic Bibliography (Ghent University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I32597200","host_organization_name":"Ghent University","host_organization_lineage":["https://openalex.org/I32597200"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"ISSN: 1521-3765","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:pubmedcentral.nih.gov:4676915","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC4676915/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chemistry","raw_type":"Text"},{"id":"pmh:oai:eprints.soton.ac.uk:384493","doi":null,"is_oa":false,"landing_page_url":"http://doi.org/10.1002/chem.201503253>).","pdf_url":null,"source":{"id":"https://openalex.org/S4306401019","display_name":"ePrints Soton (University of Southampton)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I43439940","host_organization_name":"University of Southampton","host_organization_lineage":["https://openalex.org/I43439940"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Article"},{"id":"pmh:oai:HAL:hal-02141598v1","doi":null,"is_oa":false,"landing_page_url":"https://hal.science/hal-02141598","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4405252976","host_organization_name":"Centre pour la Communication Scientifique Directe","host_organization_lineage":["https://openalex.org/I4405252976"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Chemistry - A European Journal, 2015, 21 (49), pp.17808-17816. ⟨10.1002/chem.201503253⟩","raw_type":"info:eu-repo/semantics/article"},{"id":"mag:2946963015","doi":null,"is_oa":false,"landing_page_url":"https://hal.archives-ouvertes.fr/hal-02141598","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"doi:10.1002/chem.201503253","doi":"https://doi.org/10.1002/chem.201503253","is_oa":true,"landing_page_url":"https://doi.org/10.1002/chem.201503253","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/chem.201503253","source":{"id":"https://openalex.org/S68911691","display_name":"Chemistry - A European Journal","issn_l":"0947-6539","issn":["0947-6539","1521-3765"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chemistry \u2013 A European Journal","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G2121391318","display_name":"Probing Organic Fluorine Effects on molecular properties","funder_award_id":"ANR-13-JS08-0007","funder_id":"https://openalex.org/F4320320883","funder_display_name":"Agence Nationale de la Recherche"},{"id":"https://openalex.org/G3434046457","display_name":"Nucl\u00e9aire pour la Sant\u00e9","funder_award_id":"ANR-11-EQPX-0004","funder_id":"https://openalex.org/F4320320883","funder_display_name":"Agence Nationale de la Recherche"},{"id":"https://openalex.org/G6877965117","display_name":"Investigating the influence of fluorination on hydrogen bonding properties of functional groups","funder_award_id":"EP/K016938/1","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"},{"id":"https://openalex.org/G7428474507","display_name":null,"funder_award_id":"EP/K016938/1","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"},{"id":"https://openalex.org/G7875997330","display_name":null,"funder_award_id":"EP/K039466","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"},{"id":"https://openalex.org/G8774591309","display_name":null,"funder_award_id":"c2014085117","funder_id":"https://openalex.org/F4320326256","funder_display_name":"Grand \u00c9quipement National De Calcul Intensif"},{"id":"https://openalex.org/G910323543","display_name":"Core Capability for Chemistry Research in Southampton","funder_award_id":"EP/K039466/1","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"}],"funders":[{"id":"https://openalex.org/F4320320883","display_name":"Agence Nationale de la Recherche","ror":"https://ror.org/00rbzpz17"},{"id":"https://openalex.org/F4320326256","display_name":"Grand \u00c9quipement National De Calcul Intensif","ror":"https://ror.org/0010d1q40"},{"id":"https://openalex.org/F4320334627","display_name":"Engineering and Physical Sciences Research Council","ror":"https://ror.org/0439y7842"},{"id":"https://openalex.org/F4320337753","display_name":"Interreg","ror":null}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2104697158.pdf","grobid_xml":"https://content.openalex.org/works/W2104697158.grobid-xml"},"referenced_works_count":48,"referenced_works":["https://openalex.org/W1964094071","https://openalex.org/W1966170157","https://openalex.org/W1966949133","https://openalex.org/W1968667208","https://openalex.org/W1976859506","https://openalex.org/W1981111904","https://openalex.org/W1984119239","https://openalex.org/W1987806561","https://openalex.org/W1996095059","https://openalex.org/W2001845444","https://openalex.org/W2002352328","https://openalex.org/W2002522774","https://openalex.org/W2007647898","https://openalex.org/W2008550166","https://openalex.org/W2021833166","https://openalex.org/W2028572280","https://openalex.org/W2030841140","https://openalex.org/W2035069175","https://openalex.org/W2037479957","https://openalex.org/W2037558289","https://openalex.org/W2048254503","https://openalex.org/W2051469879","https://openalex.org/W2052038877","https://openalex.org/W2052416609","https://openalex.org/W2052872132","https://openalex.org/W2058351610","https://openalex.org/W2060011480","https://openalex.org/W2060733085","https://openalex.org/W2064415365","https://openalex.org/W2066487595","https://openalex.org/W2072261201","https://openalex.org/W2080555436","https://openalex.org/W2087043556","https://openalex.org/W2094050167","https://openalex.org/W2095964706","https://openalex.org/W2103078313","https://openalex.org/W2104919283","https://openalex.org/W2127597837","https://openalex.org/W2133055997","https://openalex.org/W2134463889","https://openalex.org/W2142075602","https://openalex.org/W2144869962","https://openalex.org/W2324273256","https://openalex.org/W2330403813","https://openalex.org/W4205797238","https://openalex.org/W4206790642","https://openalex.org/W4236048302","https://openalex.org/W4254187329"],"related_works":["https://openalex.org/W2591266708","https://openalex.org/W2559090644","https://openalex.org/W2035069175","https://openalex.org/W4206790642","https://openalex.org/W4414069087","https://openalex.org/W6999725453","https://openalex.org/W1917576490","https://openalex.org/W3158985355","https://openalex.org/W1993951272","https://openalex.org/W1963638191"],"abstract_inverted_index":{"Fluorination":[0],"is":[1,30,58,85,129],"commonly":[2],"exercised":[3],"in":[4,52,64,73],"compound":[5],"property":[6],"optimization.":[7],"However,":[8],"the":[9,24,36,61,79,93,118,140,150,162,171],"influence":[10,91],"of":[11,17,27,38,70,110,142,161,170,173,175],"fluorination":[12,123,174],"on":[13,92,117],"hydrogen-bond":[14],"(HB)":[15],"properties":[16],"adjacent":[18],"functional":[19],"groups,":[20],"as":[21,23,98],"well":[22],"HB-accepting":[25],"capacity":[26],"fluorine":[28],"itself,":[29],"still":[31],"not":[32],"completely":[33],"understood.":[34],"Although":[35],"formation":[37],"OH\u22c5\u22c5\u22c5F":[39,71,111,146,152],"intramolecular":[40],"HBs":[41],"(IMHBs)":[42],"has":[43],"been":[44],"established":[45],"for":[46,60,78,181],"conformationally":[47],"restricted":[48],"fluorohydrins,":[49],"such":[50],"interaction":[51],"flexible":[53],"compounds":[54],"remained":[55],"questionable.":[56],"Herein":[57],"demonstrated":[59],"first":[62],"time-and":[63],"contrast":[65],"to":[66,87,145],"earlier":[67],"reports-the":[68],"occurrence":[69],"IMHBs":[72,112],"acyclic":[74],"saturated":[75],"\u03b3-fluorohydrins,":[76],"even":[77],"parent":[80],"3-fluoropropan-1-ol.":[81],"The":[82,108],"relative":[83],"stereochemistry":[84],"shown":[86],"have":[88],"a":[89,136],"crucial":[90],"corresponding":[94,163],"(h1)":[95],"JOH\u22c5\u22c5\u22c5F":[96],"values,":[97],"illustrated":[99],"by":[100,131],"syn-":[101],"and":[102,105,113,125],"anti-4-fluoropentan-2-ol":[103],"(6.6":[104],"1.9":[106],"Hz).":[107],"magnitude":[109],"their":[114],"strong":[115],"dependence":[116],"overall":[119],"molecular":[120],"conformational":[121],"profile,":[122],"motif,":[124],"alkyl":[126,138],"substitution":[127],"level,":[128],"rationalized":[130],"quantum":[132],"chemical":[133],"calculations.":[134],"For":[135],"given":[137],"chain,":[139],"\"rule":[141],"shielding\"":[143],"applies":[144],"IMHB":[147,153],"energies.":[148],"Surprisingly,":[149],"predicted":[151],"energies":[154],"are":[155],"only":[156],"moderately":[157],"weaker":[158],"than":[159],"these":[160],"OH\u22c5\u22c5\u22c5OMe.":[164],"These":[165],"results":[166],"provide":[167],"new":[168],"insights":[169],"impact":[172],"aliphatic":[176],"alcohols,":[177],"with":[178],"attractive":[179],"perspectives":[180],"rational":[182],"drug":[183],"design.":[184]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":5},{"year":2020,"cited_by_count":6},{"year":2019,"cited_by_count":7},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":6},{"year":2016,"cited_by_count":7},{"year":2015,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}