{"id":"https://openalex.org/W2104645520","doi":"https://doi.org/10.2337/diabetes.53.2007.s130","title":"The Biology of Mitochondrial Uncoupling Proteins","display_name":"The Biology of Mitochondrial Uncoupling Proteins","publication_year":2004,"publication_date":"2004-02-01","ids":{"openalex":"https://openalex.org/W2104645520","doi":"https://doi.org/10.2337/diabetes.53.2007.s130","mag":"2104645520","pmid":"https://pubmed.ncbi.nlm.nih.gov/14749278"},"language":"en","primary_location":{"id":"doi:10.2337/diabetes.53.2007.s130","doi":"https://doi.org/10.2337/diabetes.53.2007.s130","is_oa":false,"landing_page_url":"https://doi.org/10.2337/diabetes.53.2007.s130","pdf_url":null,"source":{"id":"https://openalex.org/S129060628","display_name":"Diabetes","issn_l":"0012-1797","issn":["0012-1797","1939-327X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320274","host_organization_name":"American Diabetes Association","host_organization_lineage":["https://openalex.org/P4310320274"],"host_organization_lineage_names":["American Diabetes Association"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diabetes","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5113800508","display_name":"Sophie Rousset","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I4210086369","display_name":"Institut Necker Enfants Malades","ror":"https://ror.org/000nhq538","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I4210086369","https://openalex.org/I4210096427"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Sophie Rousset","raw_affiliation_strings":["From the Centre National de la Recherche Scientifique, Unite\u0301 Propre de Recherche 9078, Faculte\u0301 de Me\u0301decine and Institut de Recherches Necker-Enfants Malades (IRNEM), Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Centre National de la Recherche Scientifique, Unite\u0301 Propre de Recherche 9078, Faculte\u0301 de Me\u0301decine and Institut de Recherches Necker-Enfants Malades (IRNEM), Paris, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I4210086369"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039733651","display_name":"Marie\u2010Clotilde Alves\u2010Guerra","orcid":"https://orcid.org/0000-0002-7918-1216","observed_orcids":["https://orcid.org/0000-0002-7918-1216"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I4210086369","display_name":"Institut Necker Enfants Malades","ror":"https://ror.org/000nhq538","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I4210086369","https://openalex.org/I4210096427"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Marie-Clotilde Alves-Guerra","raw_affiliation_strings":["From the Centre National de la Recherche Scientifique, Unite\u0301 Propre de Recherche 9078, Faculte\u0301 de Me\u0301decine and Institut de Recherches Necker-Enfants Malades (IRNEM), Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Centre National de la Recherche Scientifique, Unite\u0301 Propre de Recherche 9078, Faculte\u0301 de Me\u0301decine and Institut de Recherches Necker-Enfants Malades (IRNEM), Paris, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I4210086369"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017435110","display_name":"Julien Mozo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I4210086369","display_name":"Institut Necker Enfants Malades","ror":"https://ror.org/000nhq538","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I4210086369","https://openalex.org/I4210096427"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Julien Mozo","raw_affiliation_strings":["From the Centre National de la Recherche Scientifique, Unite\u0301 Propre de Recherche 9078, Faculte\u0301 de Me\u0301decine and Institut de Recherches Necker-Enfants Malades (IRNEM), Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Centre National de la Recherche Scientifique, Unite\u0301 Propre de Recherche 9078, Faculte\u0301 de Me\u0301decine and Institut de Recherches Necker-Enfants Malades (IRNEM), Paris, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I4210086369"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053569310","display_name":"Bruno Miroux","orcid":"https://orcid.org/0000-0002-3066-4700","observed_orcids":["https://orcid.org/0000-0002-3066-4700"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I4210086369","display_name":"Institut Necker Enfants Malades","ror":"https://ror.org/000nhq538","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I4210086369","https://openalex.org/I4210096427"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Bruno Miroux","raw_affiliation_strings":["From the Centre National de la Recherche Scientifique, Unite\u0301 Propre de Recherche 9078, Faculte\u0301 de Me\u0301decine and Institut de Recherches Necker-Enfants Malades (IRNEM), Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Centre National de la Recherche Scientifique, Unite\u0301 Propre de Recherche 9078, Faculte\u0301 de Me\u0301decine and Institut de Recherches Necker-Enfants Malades (IRNEM), Paris, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I4210086369"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082602423","display_name":"Anne\u2010Marie Cassard","orcid":"https://orcid.org/0000-0002-1813-5128","observed_orcids":["https://orcid.org/0000-0002-1813-5128"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I4210086369","display_name":"Institut Necker Enfants Malades","ror":"https://ror.org/000nhq538","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I4210086369","https://openalex.org/I4210096427"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Anne-Marie Cassard-Doulcier","raw_affiliation_strings":["From the Centre National de la Recherche Scientifique, Unite\u0301 Propre de Recherche 9078, Faculte\u0301 de Me\u0301decine and Institut de Recherches Necker-Enfants Malades (IRNEM), Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Centre National de la Recherche Scientifique, Unite\u0301 Propre de Recherche 9078, Faculte\u0301 de Me\u0301decine and Institut de Recherches Necker-Enfants Malades (IRNEM), Paris, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I4210086369"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004962893","display_name":"Fr\u00e9d\u00e9ric Bouillaud","orcid":"https://orcid.org/0000-0002-7518-9237","observed_orcids":["https://orcid.org/0000-0002-7518-9237"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I4210086369","display_name":"Institut Necker Enfants Malades","ror":"https://ror.org/000nhq538","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I4210086369","https://openalex.org/I4210096427"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Fre\u0301de\u0301ric Bouillaud","raw_affiliation_strings":["From the Centre National de la Recherche Scientifique, Unite\u0301 Propre de Recherche 9078, Faculte\u0301 de Me\u0301decine and Institut de Recherches Necker-Enfants Malades (IRNEM), Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Centre National de la Recherche Scientifique, Unite\u0301 Propre de Recherche 9078, Faculte\u0301 de Me\u0301decine and Institut de Recherches Necker-Enfants Malades (IRNEM), Paris, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I4210086369"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5028006447","display_name":"Daniel Ricquier","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I4210086369","display_name":"Institut Necker Enfants Malades","ror":"https://ror.org/000nhq538","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I4210086369","https://openalex.org/I4210096427"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Daniel Ricquier","raw_affiliation_strings":["From the Centre National de la Recherche Scientifique, Unite\u0301 Propre de Recherche 9078, Faculte\u0301 de Me\u0301decine and Institut de Recherches Necker-Enfants Malades (IRNEM), Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Centre National de la Recherche Scientifique, Unite\u0301 Propre de Recherche 9078, Faculte\u0301 de Me\u0301decine and Institut de Recherches Necker-Enfants Malades (IRNEM), Paris, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I4210086369"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":2.7561,"has_fulltext":false,"cited_by_count":560,"citation_normalized_percentile":{"value":0.93510247,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":97,"max":100},"biblio":{"volume":"53","issue":"suppl_1","first_page":"S130","last_page":"S135"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10301","display_name":"Mitochondrial Function and Pathology","score":0.9721999764442444,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10301","display_name":"Mitochondrial Function and Pathology","score":0.9721999764442444,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11457","display_name":"Adipose Tissue and Metabolism","score":0.020400000736117363,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11339","display_name":"Metabolism, Diabetes, and Cancer","score":0.0019000000320374966,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/uncoupling-proteins","display_name":"uncoupling proteins","score":0.8799999952316284},{"id":"https://openalex.org/keywords/ucp1","display_name":"UCP1","score":0.8820000290870667},{"id":"https://openalex.org/keywords/ucp2","display_name":"UCP2","score":0.996999979019165},{"id":"https://openalex.org/keywords/ucp3","display_name":"UCP3","score":1.0},{"id":"https://openalex.org/keywords/adenine-nucleotide-transporter","display_name":"adenine nucleotide transporter","score":0.8920000195503235},{"id":"https://openalex.org/keywords/thermogenesis","display_name":"thermogenesis","score":0.7300000190734863},{"id":"https://openalex.org/keywords/brown-adipocytes","display_name":"brown adipocytes","score":0.9369999766349792},{"id":"https://openalex.org/keywords/proton-carriers","display_name":"proton carriers","score":0.47699999809265137},{"id":"https://openalex.org/keywords/free-fatty-acids","display_name":"free fatty acids","score":0.7239999771118164},{"id":"https://openalex.org/keywords/reactive-oxygen-species","display_name":"reactive oxygen species","score":0.6489999890327454},{"id":"https://openalex.org/keywords/insulin-secretion","display_name":"insulin secretion","score":0.9390000104904175},{"id":"https://openalex.org/keywords/fatty-acid-metabolism","display_name":"fatty acid metabolism","score":0.906000018119812},{"id":"https://openalex.org/keywords/skeletal-muscle","display_name":"skeletal muscle","score":0.8690000176429749},{"id":"https://openalex.org/keywords/lymphoid-tissue","display_name":"lymphoid tissue","score":0.5249999761581421},{"id":"https://openalex.org/keywords/macrophages","display_name":"macrophages","score":0.746999979019165},{"id":"https://openalex.org/keywords/pancreatic-islets","display_name":"pancreatic islets","score":0.9700000286102295}],"concepts":[{"id":"https://openalex.org/C2779299233","wikidata":"https://www.wikidata.org/wiki/Q7864100","display_name":"UCP3","level":5,"score":0.9659135937690735},{"id":"https://openalex.org/C2779406938","wikidata":"https://www.wikidata.org/wiki/Q24720289","display_name":"Uncoupling protein","level":4,"score":0.8890790939331055},{"id":"https://openalex.org/C81979416","wikidata":"https://www.wikidata.org/wiki/Q419493","display_name":"Thermogenin","level":4,"score":0.8536930084228516},{"id":"https://openalex.org/C28859421","wikidata":"https://www.wikidata.org/wiki/Q39572","display_name":"Mitochondrion","level":2,"score":0.6411292552947998},{"id":"https://openalex.org/C151279926","wikidata":"https://www.wikidata.org/wiki/Q965695","display_name":"Thermogenesis","level":3,"score":0.6222215294837952},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6185043454170227},{"id":"https://openalex.org/C75385678","wikidata":"https://www.wikidata.org/wiki/Q4896390","display_name":"Inner mitochondrial membrane","level":3,"score":0.5424633026123047},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5131750702857971},{"id":"https://openalex.org/C112243037","wikidata":"https://www.wikidata.org/wiki/Q22327117","display_name":"ATP synthase","level":3,"score":0.5076471567153931},{"id":"https://openalex.org/C145488412","wikidata":"https://www.wikidata.org/wiki/Q425007","display_name":"Mitochondrial carrier","level":5,"score":0.5061601996421814},{"id":"https://openalex.org/C2780642333","wikidata":"https://www.wikidata.org/wiki/Q901269","display_name":"Brown adipose tissue","level":3,"score":0.5016424655914307},{"id":"https://openalex.org/C2910689142","wikidata":"https://www.wikidata.org/wiki/Q65089491","display_name":"Uncoupling Agents","level":3,"score":0.4629009962081909},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.4492380917072296},{"id":"https://openalex.org/C3020377403","wikidata":"https://www.wikidata.org/wiki/Q211016","display_name":"Respiratory chain","level":3,"score":0.4241895079612732},{"id":"https://openalex.org/C146587185","wikidata":"https://www.wikidata.org/wiki/Q258248","display_name":"Bacterial outer membrane","level":4,"score":0.1757722795009613},{"id":"https://openalex.org/C171089720","wikidata":"https://www.wikidata.org/wiki/Q193583","display_name":"Adipose tissue","level":2,"score":0.15793296694755554},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.07868129014968872},{"id":"https://openalex.org/C547475151","wikidata":"https://www.wikidata.org/wiki/Q25419","display_name":"Escherichia coli","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D000071246","descriptor_name":"Uncoupling Protein 2","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000071247","descriptor_name":"Uncoupling Protein 3","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000071256","descriptor_name":"Uncoupling Protein 1","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002352","descriptor_name":"Carrier Proteins","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007425","descriptor_name":"Intracellular Membranes","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D007473","descriptor_name":"Ion Channels","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008565","descriptor_name":"Membrane Proteins","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D017382","descriptor_name":"Reactive Oxygen Species","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D024101","descriptor_name":"Mitochondrial Proteins","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D026901","descriptor_name":"Membrane Transport Proteins","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.2337/diabetes.53.2007.s130","doi":"https://doi.org/10.2337/diabetes.53.2007.s130","is_oa":false,"landing_page_url":"https://doi.org/10.2337/diabetes.53.2007.s130","pdf_url":null,"source":{"id":"https://openalex.org/S129060628","display_name":"Diabetes","issn_l":"0012-1797","issn":["0012-1797","1939-327X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320274","host_organization_name":"American Diabetes Association","host_organization_lineage":["https://openalex.org/P4310320274"],"host_organization_lineage_names":["American Diabetes Association"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diabetes","raw_type":"journal-article"},{"id":"pmid:14749278","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/14749278","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diabetes","raw_type":"Journal Article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.865.9186","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.865.9186","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://diabetes.diabetesjournals.org/content/53/suppl_1/S130.full.pdf","raw_type":"text"},{"id":"pmh:oai:HAL:hal-03054734v1","doi":null,"is_oa":false,"landing_page_url":"https://hal.science/hal-03054734","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4405252976","host_organization_name":"Centre pour la Communication Scientifique Directe","host_organization_lineage":["https://openalex.org/I4405252976"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Diabetes, 2004, 53 (Supplement 1), pp.S130-S135. &#x27E8;10.2337/diabetes.53.2007.s130&#x27E9;","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320322892","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73"},{"id":"https://openalex.org/F4320336093","display_name":"Institut de Recherches Servier","ror":"https://ror.org/01zej3n42"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":59,"referenced_works":["https://openalex.org/W56406267","https://openalex.org/W105405631","https://openalex.org/W111498719","https://openalex.org/W324221867","https://openalex.org/W1486306395","https://openalex.org/W1594539479","https://openalex.org/W1638404651","https://openalex.org/W1849928642","https://openalex.org/W1900866157","https://openalex.org/W1962155705","https://openalex.org/W1970080134","https://openalex.org/W1987325894","https://openalex.org/W1996961043","https://openalex.org/W1997065838","https://openalex.org/W1999489764","https://openalex.org/W1999946108","https://openalex.org/W2008172969","https://openalex.org/W2014348989","https://openalex.org/W2023530279","https://openalex.org/W2025155785","https://openalex.org/W2027059985","https://openalex.org/W2028505124","https://openalex.org/W2032301380","https://openalex.org/W2032814494","https://openalex.org/W2034244149","https://openalex.org/W2036573181","https://openalex.org/W2042063357","https://openalex.org/W2045838525","https://openalex.org/W2051826214","https://openalex.org/W2057498089","https://openalex.org/W2062073832","https://openalex.org/W2069015292","https://openalex.org/W2076944010","https://openalex.org/W2079185127","https://openalex.org/W2083385526","https://openalex.org/W2092823267","https://openalex.org/W2096712675","https://openalex.org/W2101870887","https://openalex.org/W2107715223","https://openalex.org/W2108479537","https://openalex.org/W2114030067","https://openalex.org/W2114852939","https://openalex.org/W2115589168","https://openalex.org/W2118614496","https://openalex.org/W2122955897","https://openalex.org/W2127265700","https://openalex.org/W2130962964","https://openalex.org/W2136689463","https://openalex.org/W2147128975","https://openalex.org/W2147447839","https://openalex.org/W2153667576","https://openalex.org/W2154568954","https://openalex.org/W2156172044","https://openalex.org/W2164190249","https://openalex.org/W2170492140","https://openalex.org/W2395239076","https://openalex.org/W2416209588","https://openalex.org/W4236286856","https://openalex.org/W4248187066"],"related_works":["https://openalex.org/W4245389374","https://openalex.org/W4238499171","https://openalex.org/W7099596574","https://openalex.org/W2416883402","https://openalex.org/W2027059985","https://openalex.org/W2081614307","https://openalex.org/W2337936516","https://openalex.org/W2412060960","https://openalex.org/W1992980627","https://openalex.org/W2022234163"],"abstract_inverted_index":{"Uncoupling":[0],"proteins":[1],"(UCPs)":[2],"are":[3,14],"mitochondrial":[4,29],"transporters":[5],"present":[6,47],"in":[7,16,20,48,60,100,117,129,150,157,161,178],"the":[8,25,53,84,96,118,135,151],"inner":[9],"membrane":[10],"of":[11,27,50,83,91,106,141,153,171],"mitochondria.":[12],"They":[13,22],"found":[15],"all":[17],"mammals":[18],"and":[19,77,87,95,104,114,122,138,144,164,174],"plants.":[21],"belong":[23],"to":[24,134,147],"family":[26],"anion":[28],"carriers":[30],"including":[31],"adenine":[32],"nucleotide":[33],"transporters.":[34],"The":[35],"term":[36],"\"uncoupling":[37],"protein\"":[38],"was":[39],"originally":[40],"used":[41],"for":[42],"UCP1,":[43,142],"which":[44],"is":[45,112,126,168,176],"uniquely":[46],"mitochondria":[49],"brown":[51],"adipocytes,":[52],"thermogenic":[54,139],"cells":[55,158],"that":[56],"maintain":[57],"body":[58],"temperature":[59],"small":[61],"rodents.":[62],"In":[63,132],"these":[64],"cells,":[65],"UCP1":[66,92],"acts":[67],"as":[68,109],"a":[69,79,101,169],"proton":[70],"carrier":[71],"activated":[72],"by":[73],"free":[74,154],"fatty":[75,179],"acids":[76],"creates":[78],"shunt":[80],"between":[81],"complexes":[82],"respiratory":[85],"chain":[86],"ATP":[88],"synthase.":[89],"Activation":[90],"enhances":[93],"respiration,":[94],"uncoupling":[97,137,163],"process":[98],"results":[99],"futile":[102],"cycle":[103],"dissipation":[105],"oxidation":[107],"energy":[108],"heat.":[110],"UCP2":[111,143,167],"ubiquitous":[113],"highly":[115],"expressed":[116,128],"lymphoid":[119],"system,":[120],"macrophages,":[121],"pancreatic":[123],"islets.":[124],"UCP3":[125,145,175],"mainly":[127],"skeletal":[130],"muscles.":[131],"comparison":[133],"established":[136],"activities":[140],"appear":[146],"be":[148],"involved":[149,177],"limitation":[152],"radical":[155],"levels":[156],"rather":[159],"than":[160],"physiological":[162],"thermogenesis.":[165],"Moreover,":[166],"regulator":[170],"insulin":[172],"secretion":[173],"acid":[180],"metabolism.":[181]},"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":17},{"year":2024,"cited_by_count":11},{"year":2023,"cited_by_count":13},{"year":2022,"cited_by_count":23},{"year":2021,"cited_by_count":38},{"year":2020,"cited_by_count":22},{"year":2019,"cited_by_count":20},{"year":2018,"cited_by_count":37},{"year":2017,"cited_by_count":26},{"year":2016,"cited_by_count":40},{"year":2015,"cited_by_count":35},{"year":2014,"cited_by_count":30},{"year":2013,"cited_by_count":28},{"year":2012,"cited_by_count":25}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}
