{"id":"https://openalex.org/W2104622135","doi":"https://doi.org/10.1196/annals.1364.010","title":"Toward a Psychobiology of Posttraumatic Self\u2010Dysregulation","display_name":"Toward a Psychobiology of Posttraumatic Self\u2010Dysregulation","publication_year":2006,"publication_date":"2006-07-01","ids":{"openalex":"https://openalex.org/W2104622135","doi":"https://doi.org/10.1196/annals.1364.010","mag":"2104622135","pmid":"https://pubmed.ncbi.nlm.nih.gov/16891566"},"language":"en","primary_location":{"id":"doi:10.1196/annals.1364.010","doi":"https://doi.org/10.1196/annals.1364.010","is_oa":false,"landing_page_url":"https://doi.org/10.1196/annals.1364.010","pdf_url":null,"source":{"id":"https://openalex.org/S8802318","display_name":"Annals of the New York Academy of Sciences","issn_l":"0077-8923","issn":["0077-8923","1749-6632"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of the New York Academy of Sciences","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5020196831","display_name":"Paul Frewen","orcid":"https://orcid.org/0000-0003-3578-4776","observed_orcids":["https://orcid.org/0000-0003-3578-4776"]},"institutions":[{"id":"https://openalex.org/I125749732","display_name":"Western University","ror":"https://ror.org/02grkyz14","country_code":"CA","type":"education","lineage":["https://openalex.org/I125749732"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"PAUL A. FREWEN","raw_affiliation_strings":["Department of Psychology, The University of Western Ontario (UWO), N6A 5C2 London, Ontario, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychology, The University of Western Ontario (UWO), N6A 5C2 London, Ontario, Canada","institution_ids":["https://openalex.org/I125749732"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5051255489","display_name":"Ruth A. Lanius","orcid":"https://orcid.org/0000-0002-3758-1393","observed_orcids":["https://orcid.org/0000-0002-3758-1393"]},"institutions":[{"id":"https://openalex.org/I125749732","display_name":"Western University","ror":"https://ror.org/02grkyz14","country_code":"CA","type":"education","lineage":["https://openalex.org/I125749732"]},{"id":"https://openalex.org/I2800925808","display_name":"London Health Sciences Centre","ror":"https://ror.org/037tz0e16","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2800925808"]}],"countries":["CA"],"is_corresponding":true,"raw_author_name":"RUTH A. LANIUS","raw_affiliation_strings":["Departments of Psychiatry and Neuroscience, UWO and London Health Sciences Centre, N6A 5A5 London, Ontario, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Psychiatry and Neuroscience, UWO and London Health Sciences Centre, N6A 5A5 London, Ontario, Canada","institution_ids":["https://openalex.org/I125749732","https://openalex.org/I2800925808"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5051255489"],"corresponding_institution_ids":["https://openalex.org/I125749732","https://openalex.org/I2800925808"],"apc_list":{"value":5080,"currency":"USD","value_usd":5080},"apc_paid":null,"fwci":1.714,"has_fulltext":false,"cited_by_count":330,"citation_normalized_percentile":{"value":0.82430213,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"1071","issue":"1","first_page":"110","last_page":"124"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10242","display_name":"Posttraumatic Stress Disorder Research","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/3203","display_name":"Clinical Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},"topics":[{"id":"https://openalex.org/T10242","display_name":"Posttraumatic Stress Disorder Research","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/3203","display_name":"Clinical Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T11132","display_name":"Psychoanalysis and Psychopathology Research","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/3203","display_name":"Clinical Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T10416","display_name":"Traumatic Brain Injury Research","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/posttraumatic-stress-disorder","display_name":"post-traumatic stress disorder","score":0.9990000128746033},{"id":"https://openalex.org/keywords/emotion-regulation","display_name":"emotion regulation","score":0.8569999933242798},{"id":"https://openalex.org/keywords/psychobiological-model","display_name":"psychobiological model","score":0.8240000009536743},{"id":"https://openalex.org/keywords/re-experiencing","display_name":"re-experiencing","score":0.890999972820282},{"id":"https://openalex.org/keywords/dissociation","display_name":"dissociation","score":0.9990000128746033},{"id":"https://openalex.org/keywords/neural-correlates","display_name":"neural correlates","score":0.7770000100135803},{"id":"https://openalex.org/keywords/psychological-assessment","display_name":"psychological assessment","score":0.8989999890327454},{"id":"https://openalex.org/keywords/ptsd-treatment","display_name":"PTSD treatment","score":0.5059999823570251}],"concepts":[{"id":"https://openalex.org/C138917182","wikidata":"https://www.wikidata.org/wiki/Q846566","display_name":"Behavioral neuroscience","level":2,"score":0.7686348557472229},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.7409589290618896},{"id":"https://openalex.org/C123273963","wikidata":"https://www.wikidata.org/wiki/Q624758","display_name":"Psychopathology","level":2,"score":0.7383670806884766},{"id":"https://openalex.org/C36951298","wikidata":"https://www.wikidata.org/wiki/Q379784","display_name":"Arousal","level":2,"score":0.7284601330757141},{"id":"https://openalex.org/C102931765","wikidata":"https://www.wikidata.org/wiki/Q189673","display_name":"Dissociation (chemistry)","level":2,"score":0.6415287256240845},{"id":"https://openalex.org/C58693492","wikidata":"https://www.wikidata.org/wiki/Q551875","display_name":"Neuroimaging","level":2,"score":0.5483071804046631},{"id":"https://openalex.org/C2776035688","wikidata":"https://www.wikidata.org/wiki/Q1606558","display_name":"Affect (linguistics)","level":2,"score":0.5234531760215759},{"id":"https://openalex.org/C2991847609","wikidata":"https://www.wikidata.org/wiki/Q202387","display_name":"Posttraumatic stress","level":2,"score":0.4708532691001892},{"id":"https://openalex.org/C70410870","wikidata":"https://www.wikidata.org/wiki/Q199906","display_name":"Clinical psychology","level":1,"score":0.4248017966747284},{"id":"https://openalex.org/C129564537","wikidata":"https://www.wikidata.org/wiki/Q1460873","display_name":"Neural correlates of consciousness","level":3,"score":0.4180294871330261},{"id":"https://openalex.org/C3018364700","wikidata":"https://www.wikidata.org/wiki/Q65089653","display_name":"Affect regulation","level":3,"score":0.41449421644210815},{"id":"https://openalex.org/C542102704","wikidata":"https://www.wikidata.org/wiki/Q183257","display_name":"Psychotherapist","level":1,"score":0.38881585001945496},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.24186846613883972},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.2247161865234375},{"id":"https://openalex.org/C169900460","wikidata":"https://www.wikidata.org/wiki/Q2200417","display_name":"Cognition","level":2,"score":0.11666762828826904},{"id":"https://openalex.org/C46312422","wikidata":"https://www.wikidata.org/wiki/Q11024","display_name":"Communication","level":1,"score":0.0},{"id":"https://openalex.org/C119477188","wikidata":"https://www.wikidata.org/wiki/Q909609","display_name":"Attachment theory","level":2,"score":0.0},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.0},{"id":"https://openalex.org/C147789679","wikidata":"https://www.wikidata.org/wiki/Q11372","display_name":"Physical chemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000223","descriptor_name":"Adaptation, Psychological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001143","descriptor_name":"Arousal","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D004213","descriptor_name":"Dissociative Disorders","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D004213","descriptor_name":"Dissociative Disorders","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":true},{"descriptor_ui":"D004644","descriptor_name":"Emotions","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011939","descriptor_name":"Mental Recall","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013313","descriptor_name":"Stress Disorders, Post-Traumatic","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D013313","descriptor_name":"Stress Disorders, Post-Traumatic","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D013313","descriptor_name":"Stress Disorders, Post-Traumatic","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":true},{"descriptor_ui":"D014947","descriptor_name":"Wounds and Injuries","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1196/annals.1364.010","doi":"https://doi.org/10.1196/annals.1364.010","is_oa":false,"landing_page_url":"https://doi.org/10.1196/annals.1364.010","pdf_url":null,"source":{"id":"https://openalex.org/S8802318","display_name":"Annals of the New York Academy of Sciences","issn_l":"0077-8923","issn":["0077-8923","1749-6632"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of the New York Academy of Sciences","raw_type":"journal-article"},{"id":"pmid:16891566","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16891566","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of the New York Academy of Sciences","raw_type":"Journal Article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.463.3370","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.463.3370","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://www.towson.edu/topddstudy/frewenlaniusdysregulationnyas.pdf","raw_type":"text"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9537000060081482}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":58,"referenced_works":["https://openalex.org/W1482544075","https://openalex.org/W1637267194","https://openalex.org/W1747782981","https://openalex.org/W1963525383","https://openalex.org/W1966297906","https://openalex.org/W1966806791","https://openalex.org/W1969227269","https://openalex.org/W1971585209","https://openalex.org/W1976275501","https://openalex.org/W1991819673","https://openalex.org/W1996154296","https://openalex.org/W1999989599","https://openalex.org/W2008286604","https://openalex.org/W2016669923","https://openalex.org/W2025266605","https://openalex.org/W2031271860","https://openalex.org/W2031992845","https://openalex.org/W2041106763","https://openalex.org/W2048087221","https://openalex.org/W2054228615","https://openalex.org/W2055210002","https://openalex.org/W2057988711","https://openalex.org/W2066525901","https://openalex.org/W2075715910","https://openalex.org/W2077234736","https://openalex.org/W2091308025","https://openalex.org/W2092354644","https://openalex.org/W2095190762","https://openalex.org/W2096423181","https://openalex.org/W2099741389","https://openalex.org/W2101809190","https://openalex.org/W2102748276","https://openalex.org/W2107751666","https://openalex.org/W2108477383","https://openalex.org/W2109699325","https://openalex.org/W2111233058","https://openalex.org/W2115972365","https://openalex.org/W2122502783","https://openalex.org/W2128234817","https://openalex.org/W2132453364","https://openalex.org/W2133664593","https://openalex.org/W2137050989","https://openalex.org/W2142823391","https://openalex.org/W2145499550","https://openalex.org/W2145702255","https://openalex.org/W2151786648","https://openalex.org/W2155045291","https://openalex.org/W2155053670","https://openalex.org/W2157171235","https://openalex.org/W2160986440","https://openalex.org/W2161447862","https://openalex.org/W2165540518","https://openalex.org/W2168700401","https://openalex.org/W2171052465","https://openalex.org/W2323884347","https://openalex.org/W2344117922","https://openalex.org/W2992364732","https://openalex.org/W3202912068"],"related_works":["https://openalex.org/W7099406124","https://openalex.org/W2801574273","https://openalex.org/W2404954574","https://openalex.org/W2124556602","https://openalex.org/W2011658150","https://openalex.org/W4247646400","https://openalex.org/W3006673809","https://openalex.org/W1593055096","https://openalex.org/W4293242511","https://openalex.org/W6942848957"],"abstract_inverted_index":{"In":[0],"this":[1,74],"article":[2],"we":[3],"propose":[4],"a":[5,13,32],"psychobiological":[6],"model":[7],"that":[8],"construes":[9],"PTSD":[10,47],"fundamentally":[11],"as":[12,31],"disorder":[14],"of":[15,21,38,42,46,73,81],"affect":[16],"arousal":[17],"regulation.":[18],"Neuroimaging":[19],"studies":[20],"emotion":[22,55],"regulation":[23,56],"in":[24,64],"psychologically":[25],"healthy":[26],"populations":[27],"are":[28],"initially":[29],"reviewed":[30],"framework":[33,57,75],"for":[34,76],"interpreting":[35],"the":[36,43,54,70],"results":[37],"previously":[39],"published":[40],"investigations":[41],"neural":[44],"correlates":[45],"reexperiencing":[48],"and":[49,79],"dissociation.":[50],"We":[51,66],"then":[52],"apply":[53],"toward":[58],"understanding":[59],"other":[60],"perturbed":[61],"affective":[62],"states":[63],"PTSD.":[65],"conclude":[67],"by":[68],"discussing":[69],"clinical":[71],"significance":[72],"psychological":[77],"assessment":[78],"treatment":[80],"posttrauma":[82],"psychopathology.":[83]},"counts_by_year":[{"year":2026,"cited_by_count":15},{"year":2025,"cited_by_count":21},{"year":2024,"cited_by_count":13},{"year":2023,"cited_by_count":18},{"year":2022,"cited_by_count":15},{"year":2021,"cited_by_count":16},{"year":2020,"cited_by_count":25},{"year":2019,"cited_by_count":17},{"year":2018,"cited_by_count":15},{"year":2017,"cited_by_count":18},{"year":2016,"cited_by_count":18},{"year":2015,"cited_by_count":30},{"year":2014,"cited_by_count":16},{"year":2013,"cited_by_count":14},{"year":2012,"cited_by_count":13}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}