{"id":"https://openalex.org/W2104549321","doi":"https://doi.org/10.1186/1477-7827-9-124","title":"Serum leptin levels in relation to circulating cytokines, chemokines, adhesion molecules and angiogenic factors in normal pregnancy and preeclampsia","display_name":"Serum leptin levels in relation to circulating cytokines, chemokines, adhesion molecules and angiogenic factors in normal pregnancy and preeclampsia","publication_year":2011,"publication_date":"2011-09-09","ids":{"openalex":"https://openalex.org/W2104549321","doi":"https://doi.org/10.1186/1477-7827-9-124","mag":"2104549321","pmid":"https://pubmed.ncbi.nlm.nih.gov/21906313","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3184629"},"language":"en","primary_location":{"id":"doi:10.1186/1477-7827-9-124","doi":"https://doi.org/10.1186/1477-7827-9-124","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1477-7827-9-124","pdf_url":"https://rbej.biomedcentral.com/counter/pdf/10.1186/1477-7827-9-124","source":{"id":"https://openalex.org/S140121985","display_name":"Reproductive Biology and Endocrinology","issn_l":"1477-7827","issn":["1477-7827"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Reproductive Biology and Endocrinology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://rbej.biomedcentral.com/counter/pdf/10.1186/1477-7827-9-124","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5059287453","display_name":"Attila Molvarec","orcid":"https://orcid.org/0000-0002-3229-3034","observed_orcids":["https://orcid.org/0000-0002-3229-3034"]},"institutions":[{"id":"https://openalex.org/I101202996","display_name":"Semmelweis University","ror":"https://ror.org/01g9ty582","country_code":"HU","type":"education","lineage":["https://openalex.org/I101202996"]}],"countries":["HU"],"is_corresponding":true,"raw_author_name":"Attila Molvarec","raw_affiliation_strings":["First Department of Obstetrics and Gynecology, Semmelweis University, Budapest, Hungary. molvarec@freemail.hu","First Dept. of Obstetrics and Gynecology, Semmelweis University, Budapest, Hungary"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"First Department of Obstetrics and Gynecology, Semmelweis University, Budapest, Hungary. molvarec@freemail.hu","institution_ids":["https://openalex.org/I101202996"]},{"raw_affiliation_string":"First Dept. of Obstetrics and Gynecology, Semmelweis University, Budapest, Hungary","institution_ids":["https://openalex.org/I101202996"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075960840","display_name":"Andr\u00e1s Szarka","orcid":"https://orcid.org/0000-0001-6594-254X","observed_orcids":["https://orcid.org/0000-0001-6594-254X"]},"institutions":[{"id":"https://openalex.org/I101202996","display_name":"Semmelweis University","ror":"https://ror.org/01g9ty582","country_code":"HU","type":"education","lineage":["https://openalex.org/I101202996"]}],"countries":["HU"],"is_corresponding":false,"raw_author_name":"Andr\u00e1s Szarka","raw_affiliation_strings":["First Department of Obstetrics and Gynecology, Semmelweis University, Budapest, Hungary","First Dept. of Obstetrics and Gynecology, Semmelweis University, Budapest, Hungary"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"First Department of Obstetrics and Gynecology, Semmelweis University, Budapest, Hungary","institution_ids":["https://openalex.org/I101202996"]},{"raw_affiliation_string":"First Dept. of Obstetrics and Gynecology, Semmelweis University, Budapest, Hungary","institution_ids":["https://openalex.org/I101202996"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109127024","display_name":"Szilvia Walentin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I101202996","display_name":"Semmelweis University","ror":"https://ror.org/01g9ty582","country_code":"HU","type":"education","lineage":["https://openalex.org/I101202996"]}],"countries":["HU"],"is_corresponding":false,"raw_author_name":"Szilvia Walentin","raw_affiliation_strings":["Central Laboratory, K\u00fatv\u00f6lgyi Clinical Center, Semmelweis University, Budapest, Hungary"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Central Laboratory, K\u00fatv\u00f6lgyi Clinical Center, Semmelweis University, Budapest, Hungary","institution_ids":["https://openalex.org/I101202996"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048096846","display_name":"Gabriella Bek\u0151","orcid":"https://orcid.org/0000-0001-8539-5897","observed_orcids":["https://orcid.org/0000-0001-8539-5897"]},"institutions":[{"id":"https://openalex.org/I101202996","display_name":"Semmelweis University","ror":"https://ror.org/01g9ty582","country_code":"HU","type":"education","lineage":["https://openalex.org/I101202996"]}],"countries":["HU"],"is_corresponding":false,"raw_author_name":"Gabriella Bek\u0151","raw_affiliation_strings":["Department of Laboratory Medicine, Semmelweis University, Budapest, Hungary"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Laboratory Medicine, Semmelweis University, Budapest, Hungary","institution_ids":["https://openalex.org/I101202996"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081492922","display_name":"Istv\u00e1n Kar\u00e1di","orcid":"https://orcid.org/0000-0002-8253-2654","observed_orcids":["https://orcid.org/0000-0002-8253-2654"]},"institutions":[{"id":"https://openalex.org/I101202996","display_name":"Semmelweis University","ror":"https://ror.org/01g9ty582","country_code":"HU","type":"education","lineage":["https://openalex.org/I101202996"]}],"countries":["HU"],"is_corresponding":false,"raw_author_name":"Istv\u00e1n Kar\u00e1di","raw_affiliation_strings":["Third Department of Internal Medicine, Semmelweis University, Budapest, Hungary"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Third Department of Internal Medicine, Semmelweis University, Budapest, Hungary","institution_ids":["https://openalex.org/I101202996"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031942816","display_name":"Zolt\u00e1n Proh\u00e1szka","orcid":"https://orcid.org/0000-0003-1761-7982","observed_orcids":["https://orcid.org/0000-0003-1761-7982"]},"institutions":[{"id":"https://openalex.org/I101202996","display_name":"Semmelweis University","ror":"https://ror.org/01g9ty582","country_code":"HU","type":"education","lineage":["https://openalex.org/I101202996"]},{"id":"https://openalex.org/I7597260","display_name":"Hungarian Academy of Sciences","ror":"https://ror.org/02ks8qq67","country_code":"HU","type":"government","lineage":["https://openalex.org/I7597260"]}],"countries":["HU"],"is_corresponding":false,"raw_author_name":"Zolt\u00e1n Proh\u00e1szka","raw_affiliation_strings":["Research Group of Inflammation Biology and Immunogenomics, Hungarian Academy of Sciences, Budapest, Hungary","Third Department of Internal Medicine, Semmelweis University, Budapest, Hungary"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Group of Inflammation Biology and Immunogenomics, Hungarian Academy of Sciences, Budapest, Hungary","institution_ids":["https://openalex.org/I7597260"]},{"raw_affiliation_string":"Third Department of Internal Medicine, Semmelweis University, Budapest, Hungary","institution_ids":["https://openalex.org/I101202996"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5108076559","display_name":"J\u00e1nos Jr. Rig\u00f3","orcid":"https://orcid.org/0000-0003-2762-6516","observed_orcids":["https://orcid.org/0000-0003-2762-6516"]},"institutions":[{"id":"https://openalex.org/I101202996","display_name":"Semmelweis University","ror":"https://ror.org/01g9ty582","country_code":"HU","type":"education","lineage":["https://openalex.org/I101202996"]}],"countries":["HU"],"is_corresponding":false,"raw_author_name":"J\u00e1nos Rig\u00f3","raw_affiliation_strings":["First Department of Obstetrics and Gynecology, Semmelweis University, Budapest, Hungary","First Dept. of Obstetrics and Gynecology, Semmelweis University, Budapest, Hungary"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"First Department of Obstetrics and Gynecology, Semmelweis University, Budapest, Hungary","institution_ids":["https://openalex.org/I101202996"]},{"raw_affiliation_string":"First Dept. of Obstetrics and Gynecology, Semmelweis University, Budapest, Hungary","institution_ids":["https://openalex.org/I101202996"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5059287453"],"corresponding_institution_ids":["https://openalex.org/I101202996"],"apc_list":{"value":3690,"currency":"USD","value_usd":3690},"apc_paid":{"value":3690,"currency":"USD","value_usd":3690},"fwci":17.3232,"has_fulltext":true,"cited_by_count":139,"citation_normalized_percentile":{"value":0.99451269,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":94,"max":100},"biblio":{"volume":"9","issue":"1","first_page":"124","last_page":"124"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10290","display_name":"Pregnancy and preeclampsia studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10290","display_name":"Pregnancy and preeclampsia studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11510","display_name":"Reproductive System and Pregnancy","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12464","display_name":"Neurological Complications and Syndromes","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/leptin","display_name":"leptin","score":0.9039999842643738},{"id":"https://openalex.org/keywords/preeclampsia","display_name":"preeclampsia","score":0.9990000128746033},{"id":"https://openalex.org/keywords/pregnancy","display_name":"pregnancy","score":0.6489999890327454},{"id":"https://openalex.org/keywords/cytokines","display_name":"cytokines","score":0.7870000004768372},{"id":"https://openalex.org/keywords/chemokines","display_name":"chemokines","score":0.996999979019165},{"id":"https://openalex.org/keywords/cell-adhesion-molecules","display_name":"adhesion molecules","score":0.9959999918937683},{"id":"https://openalex.org/keywords/angiogenic-factors","display_name":"angiogenic factors","score":0.9950000047683716},{"id":"https://openalex.org/keywords/c-reactive-protein","display_name":"C-reactive protein","score":0.902999997138977},{"id":"https://openalex.org/keywords/soluble-fms-like-tyrosine-kinase-1","display_name":"soluble fms-like tyrosine kinase-1","score":0.9369999766349792},{"id":"https://openalex.org/keywords/placental-growth-factor","display_name":"placental growth factor","score":0.9919999837875366},{"id":"https://openalex.org/keywords/interleukin-6","display_name":"interleukin-6","score":0.6679999828338623},{"id":"https://openalex.org/keywords/il-10","display_name":"IL-10","score":0.6740000247955322},{"id":"https://openalex.org/keywords/cxcl10","display_name":"CXCL10","score":0.6899999976158142},{"id":"https://openalex.org/keywords/body-mass-index","display_name":"body mass index","score":0.6830000281333923},{"id":"https://openalex.org/keywords/systolic-blood-pressure","display_name":"systolic blood pressure","score":0.7900000214576721},{"id":"https://openalex.org/keywords/birth-weight","display_name":"birth weight","score":0.9020000100135803}],"concepts":[{"id":"https://openalex.org/C2777218350","wikidata":"https://www.wikidata.org/wiki/Q61335","display_name":"Preeclampsia","level":3,"score":0.7028365135192871},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6985960006713867},{"id":"https://openalex.org/C2780613262","wikidata":"https://www.wikidata.org/wiki/Q223739","display_name":"Leptin","level":3,"score":0.682033121585846},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6745420694351196},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.6197843551635742},{"id":"https://openalex.org/C13373296","wikidata":"https://www.wikidata.org/wiki/Q421866","display_name":"Chemokine","level":3,"score":0.5768378973007202},{"id":"https://openalex.org/C17991360","wikidata":"https://www.wikidata.org/wiki/Q21173843","display_name":"Tumor necrosis factor alpha","level":2,"score":0.4733167886734009},{"id":"https://openalex.org/C16224149","wikidata":"https://www.wikidata.org/wiki/Q187637","display_name":"Cell adhesion molecule","level":2,"score":0.42844241857528687},{"id":"https://openalex.org/C2776871010","wikidata":"https://www.wikidata.org/wiki/Q18030500","display_name":"Placental growth factor","level":4,"score":0.41679641604423523},{"id":"https://openalex.org/C2778690821","wikidata":"https://www.wikidata.org/wiki/Q212354","display_name":"Cytokine","level":2,"score":0.41603440046310425},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.40951550006866455},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.3841637372970581},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.3378140330314636},{"id":"https://openalex.org/C2777025900","wikidata":"https://www.wikidata.org/wiki/Q29725","display_name":"Vascular endothelial growth factor","level":3,"score":0.23182865977287292},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1551242470741272},{"id":"https://openalex.org/C167734588","wikidata":"https://www.wikidata.org/wiki/Q4356503","display_name":"VEGF receptors","level":2,"score":0.0},{"id":"https://openalex.org/C511355011","wikidata":"https://www.wikidata.org/wiki/Q12174","display_name":"Obesity","level":2,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000072483","descriptor_name":"Placenta Growth Factor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001724","descriptor_name":"Birth Weight","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002097","descriptor_name":"C-Reactive Protein","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007231","descriptor_name":"Infant, Newborn","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011225","descriptor_name":"Pre-Eclampsia","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D011225","descriptor_name":"Pre-Eclampsia","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D011225","descriptor_name":"Pre-Eclampsia","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D011247","descriptor_name":"Pregnancy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011257","descriptor_name":"Pregnancy Proteins","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D015815","descriptor_name":"Cell Adhesion Molecules","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D015992","descriptor_name":"Body Mass Index","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016022","descriptor_name":"Case-Control Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016207","descriptor_name":"Cytokines","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D018925","descriptor_name":"Chemokines","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D020738","descriptor_name":"Leptin","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D040281","descriptor_name":"Vascular Endothelial Growth Factor Receptor-1","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D042501","descriptor_name":"Angiogenic Proteins","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D054357","descriptor_name":"Chemokine CXCL10","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false}],"locations_count":6,"locations":[{"id":"doi:10.1186/1477-7827-9-124","doi":"https://doi.org/10.1186/1477-7827-9-124","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1477-7827-9-124","pdf_url":"https://rbej.biomedcentral.com/counter/pdf/10.1186/1477-7827-9-124","source":{"id":"https://openalex.org/S140121985","display_name":"Reproductive Biology and Endocrinology","issn_l":"1477-7827","issn":["1477-7827"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Reproductive Biology and Endocrinology","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:2190661","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3184629","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:3184629","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3184629","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Reprod Biol Endocrinol","raw_type":"Text"},{"id":"pmid:21906313","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21906313","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Reproductive biology and endocrinology : RB&E","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:326250821c604b04a2f6a6e702e47cae","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/326250821c604b04a2f6a6e702e47cae","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Reproductive Biology and Endocrinology, Vol 9, Iss 1, p 124 (2011)","raw_type":"article"},{"id":"pmh:oai:repo.lib.semmelweis.hu:123456789/6359","doi":null,"is_oa":false,"landing_page_url":"http://repo.lib.semmelweis.hu//handle/123456789/6359","pdf_url":null,"source":{"id":"https://openalex.org/S4306402199","display_name":"Semmelweis University Repository (Semmelweis University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I101202996","host_organization_name":"Semmelweis University","host_organization_lineage":["https://openalex.org/I101202996"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1186/1477-7827-9-124","doi":"https://doi.org/10.1186/1477-7827-9-124","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1477-7827-9-124","pdf_url":"https://rbej.biomedcentral.com/counter/pdf/10.1186/1477-7827-9-124","source":{"id":"https://openalex.org/S140121985","display_name":"Reproductive Biology and Endocrinology","issn_l":"1477-7827","issn":["1477-7827"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Reproductive Biology and Endocrinology","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320321102","display_name":"Semmelweis Egyetem","ror":"https://ror.org/01g9ty582"},{"id":"https://openalex.org/F4320322192","display_name":"Magyar Tudom\u00e1nyos Akad\u00e9mia","ror":"https://ror.org/02ks8qq67"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2104549321.pdf","grobid_xml":"https://content.openalex.org/works/W2104549321.grobid-xml"},"referenced_works_count":65,"referenced_works":["https://openalex.org/W1493303306","https://openalex.org/W1590709474","https://openalex.org/W1966428464","https://openalex.org/W1967855498","https://openalex.org/W1974183191","https://openalex.org/W1985129279","https://openalex.org/W1992931275","https://openalex.org/W1993203791","https://openalex.org/W1996568851","https://openalex.org/W1996713062","https://openalex.org/W1998508489","https://openalex.org/W2012951157","https://openalex.org/W2019623114","https://openalex.org/W2020626901","https://openalex.org/W2031189217","https://openalex.org/W2032057669","https://openalex.org/W2035483520","https://openalex.org/W2036283983","https://openalex.org/W2043207514","https://openalex.org/W2043591623","https://openalex.org/W2044036633","https://openalex.org/W2044798581","https://openalex.org/W2045992905","https://openalex.org/W2049611684","https://openalex.org/W2050575285","https://openalex.org/W2050772837","https://openalex.org/W2054740597","https://openalex.org/W2060682066","https://openalex.org/W2066204890","https://openalex.org/W2068609294","https://openalex.org/W2074520223","https://openalex.org/W2077719773","https://openalex.org/W2078005526","https://openalex.org/W2078370514","https://openalex.org/W2079231160","https://openalex.org/W2083962256","https://openalex.org/W2087586279","https://openalex.org/W2089674666","https://openalex.org/W2090078097","https://openalex.org/W2099605002","https://openalex.org/W2101340193","https://openalex.org/W2101921785","https://openalex.org/W2104732966","https://openalex.org/W2115394551","https://openalex.org/W2118358710","https://openalex.org/W2122722123","https://openalex.org/W2123904100","https://openalex.org/W2126412697","https://openalex.org/W2126426760","https://openalex.org/W2129351675","https://openalex.org/W2131396829","https://openalex.org/W2135561577","https://openalex.org/W2137748676","https://openalex.org/W2141630700","https://openalex.org/W2142431039","https://openalex.org/W2143180984","https://openalex.org/W2145246503","https://openalex.org/W2155707964","https://openalex.org/W2159546392","https://openalex.org/W2161360846","https://openalex.org/W2164659530","https://openalex.org/W2167195831","https://openalex.org/W2168041453","https://openalex.org/W4249550771","https://openalex.org/W4312243406"],"related_works":["https://openalex.org/W2028206390","https://openalex.org/W7098326281","https://openalex.org/W2387350689","https://openalex.org/W2060261803","https://openalex.org/W2043532592","https://openalex.org/W2517976745","https://openalex.org/W1981416350","https://openalex.org/W2367092776","https://openalex.org/W2337551907","https://openalex.org/W2112164432"],"abstract_inverted_index":{"OBJECTIVE:":[0],"In":[1,238,291],"this":[2,69,353],"study,":[3],"we":[4],"determined":[5,128,159],"circulating":[6,369],"levels":[7,38,88,157,196,219,228,277,284],"of":[8,22,49,73,89,177,265,278,303,323,333,337,343,368],"C-reactive":[9,134],"protein,":[10],"several":[11,346],"cytokines,":[12],"chemokines,":[13],"adhesion":[14,118,124],"molecules":[15,348],"and":[16,27,30,33,45,61,75,121,150,191,203,244,269,305,312,349,374],"angiogenic":[17,350],"factors":[18,351],"along":[19],"with":[20,232,253,287,345],"those":[21],"leptin":[23,37,74,195,218,227,254,263,283,304,310,344,370],"in":[24,68,80,175,200,208,234,320,352,371],"healthy":[25,58,63,204,209,223,235,239,266],"non-pregnant":[26,64,210,236],"pregnant":[28,59,205,224,240,267],"women":[29,60,65,206,268],"preeclamptic":[31,55,201,213,292],"patients,":[32,56,293],"investigated":[34],"whether":[35],"serum":[36,189,245,262,276,282,301,309],"were":[39,66,83,127,138,158,168,172,197,229,257],"related":[40],"to":[41,222,357,364],"the":[42,50,178,183,321,328,366],"clinical":[43],"characteristics":[44],"measured":[46,139,179],"laboratory":[47,180],"parameters":[48,181],"study":[51,185,354],"participants.":[52],"METHODS:":[53],"Sixty":[54],"60":[57],"59":[62],"involved":[67],"case-control":[70],"study.":[71],"Levels":[72],"transforming":[76],"growth":[77,154],"factor":[78,108,155],"(TGF)-beta1":[79],"maternal":[81],"sera":[82],"assessed":[84],"by":[85,129,140,160,327],"ELISA.":[86],"Serum":[87,133,143,194,226],"interleukin":[90],"(IL)-1beta,":[91],"IL-1":[92],"receptor":[93],"antagonist":[94],"(IL-1ra),":[95],"IL-2,":[96],"IL-4,":[97],"IL-6,":[98],"IL-8,":[99],"IL-10,":[100],"IL-12p40,":[101],"IL-12p70,":[102],"IL-18,":[103],"interferon":[104],"(IFN)-gamma,":[105],"tumor":[106],"necrosis":[107],"(TNF)-alpha,":[109],"interferon-gamma-inducible":[110],"protein":[111,115,135],"(IP)-10,":[112],"monocyte":[113],"chemotactic":[114],"(MCP)-1,":[116],"intercellular":[117],"molecule":[119,125],"(ICAM)-1":[120],"vascular":[122],"cell":[123],"(VCAM)-1":[126],"multiplex":[130],"suspension":[131],"array.":[132],"(CRP)":[136],"concentrations":[137,247,264,302],"an":[141,316],"autoanalyzer.":[142],"total":[144],"soluble":[145],"fms-like":[146],"tyrosine":[147],"kinase-1":[148],"(sFlt-1)":[149],"biologically":[151],"active":[152],"placental":[153],"(PlGF)":[156],"electrochemiluminescence":[161],"immunoassay.":[162],"For":[163],"statistical":[164],"analyses,":[165],"non-parametric":[166],"methods":[167],"applied.":[169],"RESULTS:":[170],"There":[171,256],"significant":[173,249,258,295],"differences":[174],"most":[176],"among":[182],"three":[184],"groups":[186],"except":[187],"for":[188],"IL-1beta":[190],"TGF-beta1":[192],"levels.":[193,255],"significantly":[198,216],"higher":[199,217,330],"patients":[202,214],"than":[207,336],"women.":[211,225,237],"Additionally,":[212],"had":[215,315],"as":[220,273,275,325],"compared":[221],"independently":[230],"associated":[231],"BMI":[233,243],"women,":[241],"both":[242],"CRP":[246],"showed":[248],"positive":[250,259,296],"linear":[251],"association":[252],"correlations":[260],"between":[261,300],"systolic":[270],"blood":[271],"pressure,":[272],"well":[274],"IP-10,":[279],"while":[280],"their":[281,334,359],"correlated":[285],"inversely":[286],"fetal":[288],"birth":[289],"weight.":[290],"a":[294],"correlation":[297],"was":[298],"observed":[299],"IP-10.":[306],"Furthermore,":[307],"elevated":[308],"level":[311],"sFlt-1/PlGF":[313],"ratio":[314],"additive":[317],"(joint)":[318],"effect":[319],"risk":[322],"preeclampsia,":[324],"shown":[326],"substantially":[329],"odds":[331],"ratios":[332],"combination":[335],"either":[338],"alone.":[339],"CONCLUSIONS:":[340],"Simultaneous":[341],"measurement":[342],"inflammatory":[347],"enabled":[355],"us":[356],"investigate":[358],"relationship,":[360],"which":[361],"can":[362],"help":[363],"understand":[365],"role":[367],"normal":[372],"pregnancy":[373],"preeclampsia.":[375]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":7},{"year":2022,"cited_by_count":9},{"year":2021,"cited_by_count":12},{"year":2020,"cited_by_count":9},{"year":2019,"cited_by_count":9},{"year":2018,"cited_by_count":10},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":12},{"year":2015,"cited_by_count":18},{"year":2014,"cited_by_count":17},{"year":2013,"cited_by_count":16},{"year":2012,"cited_by_count":9}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}