{"id":"https://openalex.org/W2104428958","doi":"https://doi.org/10.1073/pnas.0605409104","title":"Characterization and application of single fluorescent nanodiamonds as cellular biomarkers","display_name":"Characterization and application of single fluorescent nanodiamonds as cellular biomarkers","publication_year":2007,"publication_date":"2007-01-09","ids":{"openalex":"https://openalex.org/W2104428958","doi":"https://doi.org/10.1073/pnas.0605409104","mag":"2104428958","pmid":"https://pubmed.ncbi.nlm.nih.gov/17213326","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/1783382"},"language":"en","primary_location":{"id":"doi:10.1073/pnas.0605409104","doi":"https://doi.org/10.1073/pnas.0605409104","is_oa":false,"landing_page_url":"https://doi.org/10.1073/pnas.0605409104","pdf_url":null,"source":{"id":"https://openalex.org/S125754415","display_name":"Proceedings of the National Academy of Sciences","issn_l":"0027-8424","issn":["0027-8424","1091-6490"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320052","host_organization_name":"National Academy of Sciences","host_organization_lineage":["https://openalex.org/P4310320052"],"host_organization_lineage_names":["National Academy of Sciences"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the National Academy of Sciences","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W2104428958"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC1783382/","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5065684335","display_name":"Chi-Cheng Fu","orcid":"https://orcid.org/0000-0001-8846-3808","observed_orcids":["https://orcid.org/0000-0001-8846-3808"]},"institutions":[{"id":"https://openalex.org/I4210135784","display_name":"Institute of Atomic and Molecular Sciences, Academia Sinica","ror":"https://ror.org/03haqsp75","country_code":"TW","type":"facility","lineage":["https://openalex.org/I4210135784","https://openalex.org/I84653119"]},{"id":"https://openalex.org/I84653119","display_name":"Academia Sinica","ror":"https://ror.org/05bxb3784","country_code":"TW","type":"facility","lineage":["https://openalex.org/I84653119"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Chi-Cheng Fu","raw_affiliation_strings":["*Institute of Atomic and Molecular Sciences, Academia Sinica, Taipei 106, Taiwan;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"*Institute of Atomic and Molecular Sciences, Academia Sinica, Taipei 106, Taiwan;","institution_ids":["https://openalex.org/I4210135784","https://openalex.org/I84653119"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002543266","display_name":"Hsu-Yang Lee","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I16733864","display_name":"National Taiwan University","ror":"https://ror.org/05bqach95","country_code":"TW","type":"education","lineage":["https://openalex.org/I16733864"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Hsu-Yang Lee","raw_affiliation_strings":["Department of Physics, National Taiwan University, Taipei 106, Taiwan; and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physics, National Taiwan University, Taipei 106, Taiwan; and","institution_ids":["https://openalex.org/I16733864"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015949022","display_name":"Kowa Chen","orcid":"https://orcid.org/0000-0001-6533-4413","observed_orcids":["https://orcid.org/0000-0001-6533-4413"]},"institutions":[{"id":"https://openalex.org/I4210135784","display_name":"Institute of Atomic and Molecular Sciences, Academia Sinica","ror":"https://ror.org/03haqsp75","country_code":"TW","type":"facility","lineage":["https://openalex.org/I4210135784","https://openalex.org/I84653119"]},{"id":"https://openalex.org/I84653119","display_name":"Academia Sinica","ror":"https://ror.org/05bxb3784","country_code":"TW","type":"facility","lineage":["https://openalex.org/I84653119"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Kowa Chen","raw_affiliation_strings":["*Institute of Atomic and Molecular Sciences, Academia Sinica, Taipei 106, Taiwan;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"*Institute of Atomic and Molecular Sciences, Academia Sinica, Taipei 106, Taiwan;","institution_ids":["https://openalex.org/I4210135784","https://openalex.org/I84653119"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078839256","display_name":"Tsong\u2010Shin Lim","orcid":"https://orcid.org/0000-0002-5356-1931","observed_orcids":["https://orcid.org/0000-0002-5356-1931"]},"institutions":[{"id":"https://openalex.org/I4210135784","display_name":"Institute of Atomic and Molecular Sciences, Academia Sinica","ror":"https://ror.org/03haqsp75","country_code":"TW","type":"facility","lineage":["https://openalex.org/I4210135784","https://openalex.org/I84653119"]},{"id":"https://openalex.org/I84653119","display_name":"Academia Sinica","ror":"https://ror.org/05bxb3784","country_code":"TW","type":"facility","lineage":["https://openalex.org/I84653119"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Tsong-Shin Lim","raw_affiliation_strings":["*Institute of Atomic and Molecular Sciences, Academia Sinica, Taipei 106, Taiwan;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"*Institute of Atomic and Molecular Sciences, Academia Sinica, Taipei 106, Taiwan;","institution_ids":["https://openalex.org/I4210135784","https://openalex.org/I84653119"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030440599","display_name":"Hsiao-Yun Wu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210135784","display_name":"Institute of Atomic and Molecular Sciences, Academia Sinica","ror":"https://ror.org/03haqsp75","country_code":"TW","type":"facility","lineage":["https://openalex.org/I4210135784","https://openalex.org/I84653119"]},{"id":"https://openalex.org/I84653119","display_name":"Academia Sinica","ror":"https://ror.org/05bxb3784","country_code":"TW","type":"facility","lineage":["https://openalex.org/I84653119"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Hsiao-Yun Wu","raw_affiliation_strings":["*Institute of Atomic and Molecular Sciences, Academia Sinica, Taipei 106, Taiwan;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"*Institute of Atomic and Molecular Sciences, Academia Sinica, Taipei 106, Taiwan;","institution_ids":["https://openalex.org/I4210135784","https://openalex.org/I84653119"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012200865","display_name":"Po-Keng Lin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I16733864","display_name":"National Taiwan University","ror":"https://ror.org/05bqach95","country_code":"TW","type":"education","lineage":["https://openalex.org/I16733864"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Po-Keng Lin","raw_affiliation_strings":["Department of Physics, National Taiwan University, Taipei 106, Taiwan; and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physics, National Taiwan University, Taipei 106, Taiwan; and","institution_ids":["https://openalex.org/I16733864"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078818271","display_name":"Pei\u2010Kuen Wei","orcid":"https://orcid.org/0000-0002-3002-0526","observed_orcids":["https://orcid.org/0000-0002-3002-0526"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Pei-Kuen Wei","raw_affiliation_strings":["Research Center for Applied Sciences and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Center for Applied Sciences and","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072133796","display_name":"Pei-Hsi Tsao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I16733864","display_name":"National Taiwan University","ror":"https://ror.org/05bqach95","country_code":"TW","type":"education","lineage":["https://openalex.org/I16733864"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Pei-Hsi Tsao","raw_affiliation_strings":["Department of Physics, National Taiwan University, Taipei 106, Taiwan; and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physics, National Taiwan University, Taipei 106, Taiwan; and","institution_ids":["https://openalex.org/I16733864"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065102952","display_name":"Huan\u2010Cheng Chang","orcid":"https://orcid.org/0000-0002-3515-4128","observed_orcids":["https://orcid.org/0000-0002-3515-4128","https://orcid.org/0000-0002-2503-4405"]},"institutions":[{"id":"https://openalex.org/I4210087491","display_name":"Genomics Research Center, Academia Sinica","ror":"https://ror.org/002mmyt85","country_code":"TW","type":"facility","lineage":["https://openalex.org/I4210087491","https://openalex.org/I84653119"]},{"id":"https://openalex.org/I4210135784","display_name":"Institute of Atomic and Molecular Sciences, Academia Sinica","ror":"https://ror.org/03haqsp75","country_code":"TW","type":"facility","lineage":["https://openalex.org/I4210135784","https://openalex.org/I84653119"]},{"id":"https://openalex.org/I84653119","display_name":"Academia Sinica","ror":"https://ror.org/05bxb3784","country_code":"TW","type":"facility","lineage":["https://openalex.org/I84653119"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Huan-Cheng Chang","raw_affiliation_strings":["*Institute of Atomic and Molecular Sciences, Academia Sinica, Taipei 106, Taiwan;","Genomics Research Center, Academia Sinica, Taipei 115, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"*Institute of Atomic and Molecular Sciences, Academia Sinica, Taipei 106, Taiwan;","institution_ids":["https://openalex.org/I4210135784","https://openalex.org/I84653119"]},{"raw_affiliation_string":"Genomics Research Center, Academia Sinica, Taipei 115, Taiwan","institution_ids":["https://openalex.org/I4210087491","https://openalex.org/I84653119"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5056524825","display_name":"Wunshain S. Fann","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I16733864","display_name":"National Taiwan University","ror":"https://ror.org/05bqach95","country_code":"TW","type":"education","lineage":["https://openalex.org/I16733864"]},{"id":"https://openalex.org/I4210135784","display_name":"Institute of Atomic and Molecular Sciences, Academia Sinica","ror":"https://ror.org/03haqsp75","country_code":"TW","type":"facility","lineage":["https://openalex.org/I4210135784","https://openalex.org/I84653119"]},{"id":"https://openalex.org/I84653119","display_name":"Academia Sinica","ror":"https://ror.org/05bxb3784","country_code":"TW","type":"facility","lineage":["https://openalex.org/I84653119"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Wunshain Fann","raw_affiliation_strings":["*Institute of Atomic and Molecular Sciences, Academia Sinica, Taipei 106, Taiwan;","Department of Physics, National Taiwan University, Taipei 106, Taiwan; and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"*Institute of Atomic and Molecular Sciences, Academia Sinica, Taipei 106, Taiwan;","institution_ids":["https://openalex.org/I4210135784","https://openalex.org/I84653119"]},{"raw_affiliation_string":"Department of Physics, National Taiwan University, Taipei 106, Taiwan; and","institution_ids":["https://openalex.org/I16733864"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":28.8756,"has_fulltext":false,"cited_by_count":868,"citation_normalized_percentile":{"value":0.99875219,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"104","issue":"3","first_page":"727","last_page":"732"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10478","display_name":"Diamond and Carbon-based Materials Research","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10478","display_name":"Diamond and Carbon-based Materials Research","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10540","display_name":"Advanced Fluorescence Microscopy Techniques","score":0.002199999988079071,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11240","display_name":"Luminescence and Fluorescent Materials","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/fluorescent-nanodiamonds","display_name":"fluorescent nanodiamonds","score":0.9490000009536743},{"id":"https://openalex.org/keywords/nitrogen-vacancy-centers","display_name":"nitrogen-vacancy centers","score":0.8539999723434448},{"id":"https://openalex.org/keywords/type-ib-diamond","display_name":"type Ib diamond","score":0.7319999933242798},{"id":"https://openalex.org/keywords/cell-markers","display_name":"cell markers","score":0.8519999980926514},{"id":"https://openalex.org/keywords/single-particle-tracking","display_name":"single-particle tracking","score":0.843999981880188},{"id":"https://openalex.org/keywords/photobleaching-resistance","display_name":"photobleaching resistance","score":0.8949999809265137},{"id":"https://openalex.org/keywords/fluorescence-blinking","display_name":"fluorescence blinking","score":0.968999981880188},{"id":"https://openalex.org/keywords/surface-functionalization","display_name":"surface functionalization","score":0.9070000052452087},{"id":"https://openalex.org/keywords/poly-l-lysine","display_name":"poly-L-lysine","score":0.8479999899864197},{"id":"https://openalex.org/keywords/carboxyl-groups","display_name":"carboxyl groups","score":0.8349999785423279},{"id":"https://openalex.org/keywords/hela-cells","display_name":"HeLa cells","score":0.7850000262260437},{"id":"https://openalex.org/keywords/live-cell-imaging","display_name":"live-cell imaging","score":0.7210000157356262}],"concepts":[{"id":"https://openalex.org/C91881484","wikidata":"https://www.wikidata.org/wiki/Q191807","display_name":"Fluorescence","level":2,"score":0.8356897830963135},{"id":"https://openalex.org/C31332276","wikidata":"https://www.wikidata.org/wiki/Q899750","display_name":"Photobleaching","level":3,"score":0.8278355002403259},{"id":"https://openalex.org/C2777715892","wikidata":"https://www.wikidata.org/wiki/Q16870989","display_name":"Nanodiamond","level":3,"score":0.7101306915283203},{"id":"https://openalex.org/C115537861","wikidata":"https://www.wikidata.org/wiki/Q7645993","display_name":"Surface modification","level":2,"score":0.6598449945449829},{"id":"https://openalex.org/C2776759294","wikidata":"https://www.wikidata.org/wiki/Q2833068","display_name":"Alexa Fluor","level":3,"score":0.6153451800346375},{"id":"https://openalex.org/C2776921476","wikidata":"https://www.wikidata.org/wiki/Q5283","display_name":"Diamond","level":2,"score":0.5435535311698914},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.48734840750694275},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4708782136440277},{"id":"https://openalex.org/C49853544","wikidata":"https://www.wikidata.org/wiki/Q206229","display_name":"Biomolecule","level":2,"score":0.46247875690460205},{"id":"https://openalex.org/C32909587","wikidata":"https://www.wikidata.org/wiki/Q11369","display_name":"Molecule","level":2,"score":0.43896886706352234},{"id":"https://openalex.org/C75473681","wikidata":"https://www.wikidata.org/wiki/Q188651","display_name":"Photochemistry","level":1,"score":0.4290130138397217},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.4268737733364105},{"id":"https://openalex.org/C113196181","wikidata":"https://www.wikidata.org/wiki/Q485223","display_name":"Analytical Chemistry (journal)","level":2,"score":0.34441912174224854},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.08530184626579285},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C147789679","wikidata":"https://www.wikidata.org/wiki/Q11372","display_name":"Physical chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C159985019","wikidata":"https://www.wikidata.org/wiki/Q181790","display_name":"Composite material","level":1,"score":0.0},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D005453","descriptor_name":"Fluorescence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006367","descriptor_name":"HeLa Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011107","descriptor_name":"Polylysine","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D015335","descriptor_name":"Molecular Probes","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D015335","descriptor_name":"Molecular Probes","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D015336","descriptor_name":"Molecular Probe Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D018130","descriptor_name":"Diamond","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D018130","descriptor_name":"Diamond","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D049329","descriptor_name":"Nanostructures","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D049329","descriptor_name":"Nanostructures","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D055672","descriptor_name":"Static Electricity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1073/pnas.0605409104","doi":"https://doi.org/10.1073/pnas.0605409104","is_oa":false,"landing_page_url":"https://doi.org/10.1073/pnas.0605409104","pdf_url":null,"source":{"id":"https://openalex.org/S125754415","display_name":"Proceedings of the National Academy of Sciences","issn_l":"0027-8424","issn":["0027-8424","1091-6490"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320052","host_organization_name":"National Academy of Sciences","host_organization_lineage":["https://openalex.org/P4310320052"],"host_organization_lineage_names":["National Academy of Sciences"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the National Academy of Sciences","raw_type":"journal-article"},{"id":"pmid:17213326","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17213326","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the National Academy of Sciences of the United States of America","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:1783382","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC1783382/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proc Natl Acad Sci U S A","raw_type":"Text"},{"id":"mag:3030970518","doi":null,"is_oa":false,"landing_page_url":"http://ir.sinica.edu.tw/handle/201000000A/31639","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:1783382","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC1783382/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proc Natl Acad Sci U S A","raw_type":"Text"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320310118","display_name":"National Sun Yat-sen University","ror":"https://ror.org/00mjawt10"},{"id":"https://openalex.org/F4320321040","display_name":"National Science Council","ror":"https://ror.org/02kv4zf79"},{"id":"https://openalex.org/F4320321041","display_name":"Academia Sinica","ror":"https://ror.org/05bxb3784"},{"id":"https://openalex.org/F4320321160","display_name":"Sun Yat-sen University","ror":"https://ror.org/0064kty71"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":41,"referenced_works":["https://openalex.org/W604969124","https://openalex.org/W1966548146","https://openalex.org/W1969306172","https://openalex.org/W1985809477","https://openalex.org/W1988987966","https://openalex.org/W1998948607","https://openalex.org/W2003705449","https://openalex.org/W2012012595","https://openalex.org/W2015622350","https://openalex.org/W2016175624","https://openalex.org/W2016857312","https://openalex.org/W2019192886","https://openalex.org/W2019624766","https://openalex.org/W2020806782","https://openalex.org/W2021505389","https://openalex.org/W2025713586","https://openalex.org/W2027244249","https://openalex.org/W2046775626","https://openalex.org/W2054411504","https://openalex.org/W2054455698","https://openalex.org/W2059614428","https://openalex.org/W2063325978","https://openalex.org/W2063575064","https://openalex.org/W2066943509","https://openalex.org/W2068287389","https://openalex.org/W2069496952","https://openalex.org/W2078320842","https://openalex.org/W2094375774","https://openalex.org/W2112101570","https://openalex.org/W2117331736","https://openalex.org/W2118274513","https://openalex.org/W2118685639","https://openalex.org/W2129006023","https://openalex.org/W2142917383","https://openalex.org/W2143345040","https://openalex.org/W2148924929","https://openalex.org/W2154321074","https://openalex.org/W2161347169","https://openalex.org/W2169756563","https://openalex.org/W2763374777","https://openalex.org/W4252617126"],"related_works":["https://openalex.org/W86528159","https://openalex.org/W2027244249","https://openalex.org/W1614874743","https://openalex.org/W2030587880","https://openalex.org/W2163950832","https://openalex.org/W2801745981","https://openalex.org/W7132103108","https://openalex.org/W2946609832"],"abstract_inverted_index":{"Type":[0],"Ib":[1],"diamonds":[2,38],"emit":[3],"bright":[4],"fluorescence":[5,74,130],"at":[6,104],"550-800":[7],"nm":[8],"from":[9],"nitrogen-vacancy":[10],"point":[11],"defects,":[12],"(N-V)(0)":[13],"and":[14,22,31,56,186],"(N-V)(-),":[15],"produced":[16],"by":[17],"high-energy":[18],"ion":[19],"beam":[20],"irradiation":[21],"subsequent":[23],"thermal":[24],"annealing.":[25],"The":[26,95,141,171],"emission,":[27],"together":[28],"with":[29,154,161,165,183],"noncytotoxicity":[30],"easiness":[32],"of":[33,53,58,75,85,101,109,119,125,138,144,173],"surface":[34,152],"functionalization,":[35],"makes":[36],"nano-sized":[37],"a":[39,76,86,105,135],"promising":[40],"fluorescent":[41,60,176],"probe":[42],"for":[43],"single-particle":[44,179],"tracking":[45],"in":[46,98],"heterogeneous":[47],"environments.":[48],"We":[49,65],"present":[50],"the":[51,69,73,99,113,145],"result":[52],"our":[54],"characterization":[55],"application":[57],"single":[59,77,87],"nanodiamonds":[61,177],"as":[62,91,178],"cellular":[63],"biomarkers.":[64],"found":[66],"that,":[67],"under":[68],"same":[70],"excitation":[71],"conditions,":[72],"35-nm":[78],"diamond":[79],"is":[80,181],"significantly":[81],"brighter":[82],"than":[83],"that":[84,163],"dye":[88],"molecule":[89],"such":[90],"Alexa":[92],"Fluor":[93],"546.":[94],"latter":[96],"photobleached":[97],"range":[100],"10":[102],"s":[103],"laser":[106],"power":[107],"density":[108],"10(4)":[110],"W/cm(2),":[111],"whereas":[112],"nanodiamond":[114],"particle":[115],"showed":[116],"no":[117,129],"sign":[118],"photobleaching":[120],"even":[121,150],"after":[122,151],"5":[123],"min":[124],"continuous":[126],"excitation.":[127],"Furthermore,":[128],"blinking":[131],"was":[132],"detected":[133],"within":[134],"time":[136],"resolution":[137],"1":[139],"ms.":[140],"photophysical":[142],"properties":[143],"particles":[146],"do":[147],"not":[148],"deteriorate":[149],"functionalization":[153],"carboxyl":[155],"groups,":[156],"which":[157],"form":[158],"covalent":[159],"bonding":[160],"polyL-lysines":[162],"interact":[164],"DNA":[166],"molecules":[167],"through":[168],"electrostatic":[169],"forces.":[170],"feasibility":[172],"using":[174],"surface-functionalized":[175],"biomarkers":[180],"demonstrated":[182],"both":[184],"fixed":[185],"live":[187],"HeLa":[188],"cells.":[189]},"counts_by_year":[{"year":2026,"cited_by_count":16},{"year":2025,"cited_by_count":14},{"year":2024,"cited_by_count":14},{"year":2023,"cited_by_count":36},{"year":2022,"cited_by_count":33},{"year":2021,"cited_by_count":42},{"year":2020,"cited_by_count":40},{"year":2019,"cited_by_count":42},{"year":2018,"cited_by_count":55},{"year":2017,"cited_by_count":34},{"year":2016,"cited_by_count":43},{"year":2015,"cited_by_count":59},{"year":2014,"cited_by_count":65},{"year":2013,"cited_by_count":68},{"year":2012,"cited_by_count":63}],"updated_date":"2026-11-14T11:04:58.165337","created_date":"2016-06-24T00:00:00"}