{"id":"https://openalex.org/W2104409683","doi":null,"title":"Analysis of Deinococcus radiodurans Mutants","display_name":"Analysis of Deinococcus radiodurans Mutants","publication_year":2003,"publication_date":"2003-01-01","ids":{"openalex":"https://openalex.org/W2104409683","mag":"2104409683"},"language":"it","primary_location":{"id":"pmh:oai:kops.uni-konstanz.de:123456789/8557","doi":null,"is_oa":true,"landing_page_url":"http://nbn-resolving.de/urn:nbn:de:bsz:352-opus-12272","pdf_url":"https://kops.uni-konstanz.de/server/api/core/bitstreams/9b8702f5-a8d2-47ee-92e1-fbbe0ace3f5c/content","source":{"id":"https://openalex.org/S4306401487","display_name":"KOPS (University of Konstanz)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I189712700","host_organization_name":"University of Konstanz","host_organization_lineage":["https://openalex.org/I189712700"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"doc-type:masterThesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://kops.uni-konstanz.de/server/api/core/bitstreams/9b8702f5-a8d2-47ee-92e1-fbbe0ace3f5c/content","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5041290178","display_name":"Matthias Hess","orcid":"https://orcid.org/0000-0003-0321-0380","observed_orcids":["https://orcid.org/0000-0003-0321-0380"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Matthias Hess","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-0321-0380","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5041290178"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":2,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10120","display_name":"Bacterial Genetics and Biotechnology","score":0.8070999979972839,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10120","display_name":"Bacterial Genetics and Biotechnology","score":0.8070999979972839,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10123","display_name":"DNA Repair Mechanisms","score":0.09200000017881393,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11359","display_name":"Effects of Radiation Exposure","score":0.02410000003874302,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/deinococcus-radiodurans","display_name":"Deinococcus radiodurans","score":1.0},{"id":"https://openalex.org/keywords/radioresistance-biology","display_name":"radioresistance (biology)","score":0.9789999723434448},{"id":"https://openalex.org/keywords/desiccation-resistance","display_name":"desiccation resistance","score":0.8650000095367432},{"id":"https://openalex.org/keywords/thermal-tolerance","display_name":"heat tolerance","score":0.9919999837875366},{"id":"https://openalex.org/keywords/mutant","display_name":"mutants","score":0.5059999823570251},{"id":"https://openalex.org/keywords/dna-repair","display_name":"DNA repair","score":0.9350000023841858},{"id":"https://openalex.org/keywords/dna-damage-tolerance","display_name":"DNA damage tolerance","score":0.41999998688697815},{"id":"https://openalex.org/keywords/uv-resistance","display_name":"UV resistance","score":0.3330000042915344},{"id":"https://openalex.org/keywords/dna-damaging-agents","display_name":"DNA-damaging agents","score":0.5329999923706055}],"concepts":[{"id":"https://openalex.org/C2776519032","wikidata":"https://www.wikidata.org/wiki/Q386827","display_name":"Deinococcus radiodurans","level":3,"score":0.9895822405815125},{"id":"https://openalex.org/C143065580","wikidata":"https://www.wikidata.org/wiki/Q3285695","display_name":"Mutant","level":3,"score":0.5858607888221741},{"id":"https://openalex.org/C2779561918","wikidata":"https://www.wikidata.org/wiki/Q3021315","display_name":"Deinococcus","level":4,"score":0.47002530097961426},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4094596803188324},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.2742490768432617},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.12598004937171936},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.08154815435409546}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:kops.uni-konstanz.de:123456789/8557","doi":null,"is_oa":true,"landing_page_url":"http://nbn-resolving.de/urn:nbn:de:bsz:352-opus-12272","pdf_url":"https://kops.uni-konstanz.de/server/api/core/bitstreams/9b8702f5-a8d2-47ee-92e1-fbbe0ace3f5c/content","source":{"id":"https://openalex.org/S4306401487","display_name":"KOPS (University of Konstanz)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I189712700","host_organization_name":"University of Konstanz","host_organization_lineage":["https://openalex.org/I189712700"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"doc-type:masterThesis"},{"id":"mag:2104409683","doi":null,"is_oa":false,"landing_page_url":"https://kops.uni-konstanz.de/bitstream/123456789/8557/1/Analysis_of_Deinococcus_radiodurans_Mutants.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:kops.uni-konstanz.de:123456789/8557","doi":null,"is_oa":true,"landing_page_url":"http://nbn-resolving.de/urn:nbn:de:bsz:352-opus-12272","pdf_url":"https://kops.uni-konstanz.de/server/api/core/bitstreams/9b8702f5-a8d2-47ee-92e1-fbbe0ace3f5c/content","source":{"id":"https://openalex.org/S4306401487","display_name":"KOPS (University of Konstanz)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I189712700","host_organization_name":"University of Konstanz","host_organization_lineage":["https://openalex.org/I189712700"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"doc-type:masterThesis"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320326505","display_name":"Universit\u00e4t Konstanz","ror":"https://ror.org/0546hnb39"},{"id":"https://openalex.org/F4320332504","display_name":"Uniformed Services University of the Health Sciences","ror":"https://ror.org/04r3kq386"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2104409683.pdf","grobid_xml":"https://content.openalex.org/works/W2104409683.grobid-xml"},"referenced_works_count":79,"referenced_works":["https://openalex.org/W97100931","https://openalex.org/W116546647","https://openalex.org/W600727277","https://openalex.org/W1120604741","https://openalex.org/W1514486887","https://openalex.org/W1566948447","https://openalex.org/W1570945586","https://openalex.org/W1597820140","https://openalex.org/W1669459870","https://openalex.org/W1686850210","https://openalex.org/W1857141999","https://openalex.org/W1905789791","https://openalex.org/W1919997755","https://openalex.org/W1945183390","https://openalex.org/W1962013449","https://openalex.org/W1962861052","https://openalex.org/W1963620887","https://openalex.org/W1966836394","https://openalex.org/W1972148874","https://openalex.org/W1979518248","https://openalex.org/W1988052129","https://openalex.org/W1988611177","https://openalex.org/W1989948221","https://openalex.org/W1991763904","https://openalex.org/W1998280152","https://openalex.org/W2000716863","https://openalex.org/W2002655620","https://openalex.org/W2005314819","https://openalex.org/W2011801595","https://openalex.org/W2011901330","https://openalex.org/W2017669705","https://openalex.org/W2019337806","https://openalex.org/W2020822561","https://openalex.org/W2021378955","https://openalex.org/W2034882590","https://openalex.org/W2036599268","https://openalex.org/W2037966959","https://openalex.org/W2039214343","https://openalex.org/W2040485907","https://openalex.org/W2040951800","https://openalex.org/W2041145647","https://openalex.org/W2045446521","https://openalex.org/W2054529176","https://openalex.org/W2056350783","https://openalex.org/W2061019965","https://openalex.org/W2063168088","https://openalex.org/W2063647297","https://openalex.org/W2064898137","https://openalex.org/W2065487253","https://openalex.org/W2080131197","https://openalex.org/W2085453698","https://openalex.org/W2086239383","https://openalex.org/W2086727854","https://openalex.org/W2087464459","https://openalex.org/W2098772291","https://openalex.org/W2110671526","https://openalex.org/W2113320648","https://openalex.org/W2116132837","https://openalex.org/W2118103468","https://openalex.org/W2119395436","https://openalex.org/W2122083929","https://openalex.org/W2123270185","https://openalex.org/W2133290100","https://openalex.org/W2137210858","https://openalex.org/W2140775467","https://openalex.org/W2141853650","https://openalex.org/W2144725934","https://openalex.org/W2145301542","https://openalex.org/W2148705812","https://openalex.org/W2149738995","https://openalex.org/W2154207150","https://openalex.org/W2158757371","https://openalex.org/W2163256632","https://openalex.org/W2163827697","https://openalex.org/W2165390912","https://openalex.org/W2171167071","https://openalex.org/W2274757338","https://openalex.org/W2497018686","https://openalex.org/W2576083693"],"related_works":["https://openalex.org/W2801454592","https://openalex.org/W2040951800","https://openalex.org/W2373556037","https://openalex.org/W1516489635","https://openalex.org/W2065487253","https://openalex.org/W2391121057","https://openalex.org/W2116643631","https://openalex.org/W4386450254","https://openalex.org/W206773104","https://openalex.org/W2112332629"],"abstract_inverted_index":{"The":[0],"extremely":[1],"radiation":[2,54,71,131,165,175,188,196],"resistant":[3],"vegetative":[4],"bacterium":[5],"Deinococcus":[6],"radiodurans":[7,113,141],"was":[8],"isolated":[9],"in":[10,137],"1956":[11],"from":[12,57,178],"gamma-irradiated":[13],"meat.":[14],"Since":[15],"then,":[16],"it":[17],"has":[18,81],"been":[19,82],"the":[20,27,47,107,111,128],"subject":[21],"of":[22,43,60,79,90,93],"research":[23],"aimed":[24],"at":[25,206],"understanding":[26],"genetic":[28],"mechanisms":[29,167,190],"underlying":[30],"its":[31],"resistance":[32,80,166,189],"phenotype.":[33],"In":[34],"addition":[35],"to":[36,39,67,84,153,173,198,201],"being":[37],"able":[38],"survive":[40,154],"high":[41],"doses":[42],"acute":[44,174],"gamma":[45,53,155],"radiation,":[46,156,185],"organism":[48],"can":[49],"grow":[50],"under":[51,183,194],"chronic":[52,184,195],"and":[55,72,95,120,135,145,158,186,209],"recover":[56],"a":[58],"range":[59,78],"other":[61],"DNA":[62,86,97],"damaging":[63],"conditions":[64],"including":[65],"exposure":[66,172],"desiccation,":[68,157],"ultraviolet":[69],"(UV)":[70],"chemical":[73],"genotoxic":[74],"agents.":[75],"This":[76,125],"remarkable":[77],"attributed":[83],"efficient":[85],"repair":[87],"processes":[88],"capable":[89],"mending":[91],"hundreds":[92],"single-":[94],"double-stranded":[96],"breaks":[98],"without":[99],"lethality":[100],"or":[101],"induced":[102],"mutation.":[103],"These":[104],"characteristics":[105],"were":[106,148],"impetus":[108],"for":[109,117,150,169,181,192],"sequencing":[110],"D.":[112,140],"genome,":[114],"ongoing":[115],"development":[116],"bioremediation,":[118],"proteome":[119],"whole":[121],"genome":[122],"expression":[123],"analyses.":[124],"thesis":[126],"examines":[127],"relationships":[129],"between":[130],"resistance,":[132,134],"desiccation":[133,210],"thermotolerance":[136],"three":[138],"novel":[139],"mutants":[142],"(DR0070,":[143],"DR0105,":[144],"DR2339).":[146],"Mutants":[147],"tested":[149],"their":[151],"ability":[152],"elevated":[159,207],"temperature.":[160],"Results":[161],"support":[162],"that":[163],"i)":[164],"responsible":[168,191],"survival":[170,182,193],"following":[171],"are":[176],"distinct":[177],"those":[179,202],"needed":[180],"ii)":[187],"appear":[197],"be":[199],"related":[200],"involved":[203],"with":[204],"growth":[205],"temperatures":[208],"resistance.":[211]},"counts_by_year":[{"year":2019,"cited_by_count":1}],"updated_date":"2026-10-03T13:16:28.481748","created_date":"2016-06-24T00:00:00"}