{"id":"https://openalex.org/W2104403786","doi":null,"title":"Modelling and calculation of dna damage and repair in mammalian cells induced by ionizing radiation of different quality","display_name":"Modelling and calculation of dna damage and repair in mammalian cells induced by ionizing radiation of different quality","publication_year":2013,"publication_date":"2013-05-21","ids":{"openalex":"https://openalex.org/W2104403786","mag":"2104403786"},"language":"en","primary_location":{"id":"pmh:oai:figshare.com:article/26922370","doi":null,"is_oa":false,"landing_page_url":"https://figshare.com/articles/thesis/Modelling_and_calculation_of_DNA_damage_and_repair_in_mammalian_cells_induced_by_ionizing_radiation_of_different_quality/26922370","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Thesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://hdl.handle.net/10616/41525","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5032433695","display_name":"Reza Taleei","orcid":"https://orcid.org/0000-0003-0671-3688","observed_orcids":["https://orcid.org/0000-0003-0671-3688"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Reza Taleei","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-0671-3688","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5032433695"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":5,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11359","display_name":"Effects of Radiation Exposure","score":0.43650001287460327,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11359","display_name":"Effects of Radiation Exposure","score":0.43650001287460327,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10123","display_name":"DNA Repair Mechanisms","score":0.3037000000476837,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11176","display_name":"Radiation Therapy and Dosimetry","score":0.24320000410079956,"subfield":{"id":"https://openalex.org/subfields/3108","display_name":"Radiation"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dna-repair","display_name":"DNA repair","score":0.6800000071525574},{"id":"https://openalex.org/keywords/double-strand-break-repair","display_name":"DNA double-strand break repair","score":0.7760000228881836},{"id":"https://openalex.org/keywords/ionizing-radiation","display_name":"ionizing radiation","score":0.8659999966621399},{"id":"https://openalex.org/keywords/mechanistic-mathematical-model","display_name":"mechanistic mathematical model","score":0.8579999804496765},{"id":"https://openalex.org/keywords/biochemical-kinetics","display_name":"biochemical kinetics","score":0.5260000228881836},{"id":"https://openalex.org/keywords/non-homologous-end-joining","display_name":"non-homologous end joining","score":0.8500000238418579},{"id":"https://openalex.org/keywords/homologous-recombination","display_name":"homologous recombination","score":0.9919999837875366},{"id":"https://openalex.org/keywords/microhomology-mediated-end-joining","display_name":"microhomology-mediated end joining","score":0.8989999890327454},{"id":"https://openalex.org/keywords/heterochromatin","display_name":"heterochromatin","score":0.9259999990463257},{"id":"https://openalex.org/keywords/repair-kinetics","display_name":"repair kinetics","score":0.527999997138977},{"id":"https://openalex.org/keywords/track-structure-model","display_name":"track structure model","score":0.8199999928474426},{"id":"https://openalex.org/keywords/monoenergetic-electrons","display_name":"monoenergetic electrons","score":0.8960000276565552},{"id":"https://openalex.org/keywords/ultrasoft-x-rays","display_name":"ultrasoft X-rays","score":0.9580000042915344},{"id":"https://openalex.org/keywords/radiation-quality","display_name":"radiation quality","score":0.4480000138282776},{"id":"https://openalex.org/keywords/cell-cycle","display_name":"cell cycle","score":0.621999979019165},{"id":"https://openalex.org/keywords/mammalian-cells","display_name":"mammalian cells","score":0.5799999833106995}],"concepts":[{"id":"https://openalex.org/C18231593","wikidata":"https://www.wikidata.org/wiki/Q186161","display_name":"Ionizing radiation","level":3,"score":0.896185040473938},{"id":"https://openalex.org/C134935766","wikidata":"https://www.wikidata.org/wiki/Q210538","display_name":"DNA repair","level":3,"score":0.5637098550796509},{"id":"https://openalex.org/C143425029","wikidata":"https://www.wikidata.org/wiki/Q5205747","display_name":"DNA damage","level":3,"score":0.5418281555175781},{"id":"https://openalex.org/C2779530757","wikidata":"https://www.wikidata.org/wiki/Q1207505","display_name":"Quality (philosophy)","level":2,"score":0.5312870144844055},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.4805788993835449},{"id":"https://openalex.org/C153385146","wikidata":"https://www.wikidata.org/wiki/Q18335","display_name":"Radiation","level":2,"score":0.4743329882621765},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.3909478187561035},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.3896150290966034},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3659725785255432},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3361341953277588},{"id":"https://openalex.org/C111337013","wikidata":"https://www.wikidata.org/wiki/Q2737837","display_name":"Irradiation","level":2,"score":0.3345554769039154},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.3287583589553833},{"id":"https://openalex.org/C200601418","wikidata":"https://www.wikidata.org/wiki/Q2193887","display_name":"Reliability engineering","level":1,"score":0.325227290391922},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.3230046033859253},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.31767696142196655},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.2986523509025574},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.24113181233406067},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.13267016410827637},{"id":"https://openalex.org/C185544564","wikidata":"https://www.wikidata.org/wiki/Q81197","display_name":"Nuclear physics","level":1,"score":0.13048362731933594},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"pmh:oai:figshare.com:article/26922370","doi":null,"is_oa":false,"landing_page_url":"https://figshare.com/articles/thesis/Modelling_and_calculation_of_DNA_damage_and_repair_in_mammalian_cells_induced_by_ionizing_radiation_of_different_quality/26922370","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Thesis"},{"id":"pmh:oai:openarchive.ki.se:10616/41525","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10616/41525","pdf_url":null,"source":{"id":"https://openalex.org/S4306400147","display_name":"Open Archive (Karolinska Institutet)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I28166907","host_organization_name":"Karolinska Institutet","host_organization_lineage":["https://openalex.org/I28166907"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/doctoralThesis"},{"id":"mag:2104403786","doi":null,"is_oa":false,"landing_page_url":"http://publications.ki.se/xmlui/handle/10616/41525?locale-attribute=en","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:openarchive.ki.se:10616/41525","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10616/41525","pdf_url":null,"source":{"id":"https://openalex.org/S4306400147","display_name":"Open Archive (Karolinska Institutet)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I28166907","host_organization_name":"Karolinska Institutet","host_organization_lineage":["https://openalex.org/I28166907"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/doctoralThesis"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":245,"referenced_works":["https://openalex.org/W104404459","https://openalex.org/W110155556","https://openalex.org/W195460277","https://openalex.org/W292040930","https://openalex.org/W571917742","https://openalex.org/W1264092735","https://openalex.org/W1439053251","https://openalex.org/W1494155703","https://openalex.org/W1557970645","https://openalex.org/W1961774825","https://openalex.org/W1962227076","https://openalex.org/W1963483008","https://openalex.org/W1966262413","https://openalex.org/W1966557704","https://openalex.org/W1967291554","https://openalex.org/W1969262167","https://openalex.org/W1970963436","https://openalex.org/W1971615802","https://openalex.org/W1971747664","https://openalex.org/W1972725000","https://openalex.org/W1972769310","https://openalex.org/W1973023456","https://openalex.org/W1974755980","https://openalex.org/W1975030858","https://openalex.org/W1975052508","https://openalex.org/W1975225200","https://openalex.org/W1975316919","https://openalex.org/W1976385056","https://openalex.org/W1976881265","https://openalex.org/W1978282378","https://openalex.org/W1978331091","https://openalex.org/W1978604692","https://openalex.org/W1979568780","https://openalex.org/W1979648546","https://openalex.org/W1980034972","https://openalex.org/W1981805457","https://openalex.org/W1984916442","https://openalex.org/W1985775217","https://openalex.org/W1985786559","https://openalex.org/W1986865088","https://openalex.org/W1987005816","https://openalex.org/W1988437534","https://openalex.org/W1988827197","https://openalex.org/W1989924028","https://openalex.org/W1989998334","https://openalex.org/W1992900869","https://openalex.org/W1993916591","https://openalex.org/W1994439728","https://openalex.org/W1995161918","https://openalex.org/W1995166397","https://openalex.org/W1996281999","https://openalex.org/W1996845299","https://openalex.org/W1997817263","https://openalex.org/W1998129814","https://openalex.org/W1998869208","https://openalex.org/W1999037466","https://openalex.org/W1999515288","https://openalex.org/W2000633661","https://openalex.org/W2001784394","https://openalex.org/W2002421203","https://openalex.org/W2003236929","https://openalex.org/W2003714891","https://openalex.org/W2005225437","https://openalex.org/W2007377687","https://openalex.org/W2007717932","https://openalex.org/W2007730035","https://openalex.org/W2008306394","https://openalex.org/W2009007206","https://openalex.org/W2009150623","https://openalex.org/W2009212279","https://openalex.org/W2009579361","https://openalex.org/W2009826298","https://openalex.org/W2011121831","https://openalex.org/W2012816024","https://openalex.org/W2013404388","https://openalex.org/W2013471063","https://openalex.org/W2013694269","https://openalex.org/W2016899512","https://openalex.org/W2016908381","https://openalex.org/W2016937673","https://openalex.org/W2019072372","https://openalex.org/W2019219567","https://openalex.org/W2019405732","https://openalex.org/W2020602019","https://openalex.org/W2020641167","https://openalex.org/W2023168478","https://openalex.org/W2023776747","https://openalex.org/W2024039048","https://openalex.org/W2024136831","https://openalex.org/W2024339581","https://openalex.org/W2026515265","https://openalex.org/W2027379868","https://openalex.org/W2028138760","https://openalex.org/W2029065442","https://openalex.org/W2032348296","https://openalex.org/W2032830334","https://openalex.org/W2033172828","https://openalex.org/W2034582922","https://openalex.org/W2035260679","https://openalex.org/W2036103078","https://openalex.org/W2037147607","https://openalex.org/W2037245692","https://openalex.org/W2038845073","https://openalex.org/W2039270889","https://openalex.org/W2039575792","https://openalex.org/W2040234559","https://openalex.org/W2043990544","https://openalex.org/W2044896726","https://openalex.org/W2044963929","https://openalex.org/W2046505836","https://openalex.org/W2049982841","https://openalex.org/W2050164541","https://openalex.org/W2051193631","https://openalex.org/W2052178794","https://openalex.org/W2053311488","https://openalex.org/W2055367037","https://openalex.org/W2057514567","https://openalex.org/W2057902837","https://openalex.org/W2058419441","https://openalex.org/W2061060103","https://openalex.org/W2061137324","https://openalex.org/W2061393836","https://openalex.org/W2062007210","https://openalex.org/W2064466134","https://openalex.org/W2064571311","https://openalex.org/W2068283077","https://openalex.org/W2071135218","https://openalex.org/W2071137315","https://openalex.org/W2071405540","https://openalex.org/W2072585227","https://openalex.org/W2075175820","https://openalex.org/W2075758387","https://openalex.org/W2076141468","https://openalex.org/W2077494070","https://openalex.org/W2078149643","https://openalex.org/W2079725937","https://openalex.org/W2080476839","https://openalex.org/W2082701719","https://openalex.org/W2083700555","https://openalex.org/W2083740738","https://openalex.org/W2085932935","https://openalex.org/W2086544019","https://openalex.org/W2088597183","https://openalex.org/W2090433238","https://openalex.org/W2090809088","https://openalex.org/W2091497817","https://openalex.org/W2091973234","https://openalex.org/W2092265336","https://openalex.org/W2094491029","https://openalex.org/W2094499979","https://openalex.org/W2094585311","https://openalex.org/W2097457790","https://openalex.org/W2101951083","https://openalex.org/W2103007290","https://openalex.org/W2106300281","https://openalex.org/W2106845421","https://openalex.org/W2106848547","https://openalex.org/W2108547322","https://openalex.org/W2109879947","https://openalex.org/W2110487265","https://openalex.org/W2111758302","https://openalex.org/W2114745290","https://openalex.org/W2114880854","https://openalex.org/W2119346494","https://openalex.org/W2121070277","https://openalex.org/W2121974594","https://openalex.org/W2124371549","https://openalex.org/W2126589892","https://openalex.org/W2127136618","https://openalex.org/W2127173305","https://openalex.org/W2127821590","https://openalex.org/W2128117352","https://openalex.org/W2130759927","https://openalex.org/W2131061813","https://openalex.org/W2131747287","https://openalex.org/W2131978108","https://openalex.org/W2132920733","https://openalex.org/W2134807701","https://openalex.org/W2135417045","https://openalex.org/W2136043941","https://openalex.org/W2136743671","https://openalex.org/W2136977672","https://openalex.org/W2140154770","https://openalex.org/W2141725272","https://openalex.org/W2141934899","https://openalex.org/W2142460487","https://openalex.org/W2143301911","https://openalex.org/W2143629217","https://openalex.org/W2144792857","https://openalex.org/W2145049401","https://openalex.org/W2145911077","https://openalex.org/W2146309825","https://openalex.org/W2147344015","https://openalex.org/W2147672884","https://openalex.org/W2151411596","https://openalex.org/W2152042169","https://openalex.org/W2152656791","https://openalex.org/W2154111088","https://openalex.org/W2154897918","https://openalex.org/W2156063202","https://openalex.org/W2157027723","https://openalex.org/W2157700029","https://openalex.org/W2160307554","https://openalex.org/W2160801475","https://openalex.org/W2161205189","https://openalex.org/W2161432469","https://openalex.org/W2161776046","https://openalex.org/W2162412306","https://openalex.org/W2163062435","https://openalex.org/W2163646457","https://openalex.org/W2163658254","https://openalex.org/W2163807909","https://openalex.org/W2164995160","https://openalex.org/W2165346218","https://openalex.org/W2166284889","https://openalex.org/W2167436760","https://openalex.org/W2168367012","https://openalex.org/W2169020257","https://openalex.org/W2169741450","https://openalex.org/W2170521591","https://openalex.org/W2171311732","https://openalex.org/W2171456587","https://openalex.org/W2171979690","https://openalex.org/W2172576802","https://openalex.org/W2174136697","https://openalex.org/W2175938697","https://openalex.org/W2177752528","https://openalex.org/W2178225883","https://openalex.org/W2178785249","https://openalex.org/W2179170296","https://openalex.org/W2245349746","https://openalex.org/W2322564707","https://openalex.org/W2326686334","https://openalex.org/W2333831054","https://openalex.org/W2398137183","https://openalex.org/W2398980959","https://openalex.org/W2402854553","https://openalex.org/W2416927508","https://openalex.org/W2467943975","https://openalex.org/W2469081736","https://openalex.org/W2471992955","https://openalex.org/W2626425857","https://openalex.org/W4256070116","https://openalex.org/W4294108862","https://openalex.org/W4300630256"],"related_works":["https://openalex.org/W1974260179","https://openalex.org/W4309857893","https://openalex.org/W2333210524","https://openalex.org/W4319301776","https://openalex.org/W2031671931","https://openalex.org/W2033668903","https://openalex.org/W2413031358","https://openalex.org/W4401578972","https://openalex.org/W2520178269","https://openalex.org/W2099160088"],"abstract_inverted_index":{"Recent":[0],"experimental":[1,295],"data":[2],"have":[3,409],"revealed":[4],"a":[5,16,53,103,111,158,249,345,372,393],"wealth":[6],"of":[7,19,31,47,57,71,83,94,102,132,143,157,160,182,186,197,202,205,278,284,315,352,374,382,400,419,439,461,493,519,533,550,556],"information":[8],"that":[9,37,106,164,269,337,359,376,407],"provides":[10,392],"an":[11],"exceptional":[12],"opportunity":[13,395],"to":[14,25,40,51,74,125,148,225,251,371,396,403,497],"construct":[15,52],"mechanistic":[17,54,91,316],"model":[18,56,65,93,149,155,177,199,217,224,387],"DNA":[20,32,58,119,462,557],"repair.":[21,354],"The":[22,45,63,90,153,176,195,215,272,307,327,355,385,453,484],"cellular":[23,123,401],"response":[24,124],"radiation":[26,117,126,404],"exposure":[27],"starts":[28],"with":[29,210,220,294,300],"repair":[30,59,64,72,88,95,134,151,154,207,216,231,255,266,325,368,386],"damage":[33,172,187,228],"and":[34,121,166,192,230,241,261,287,292,303,318,323,416,436,503],"cell":[35,43,109,190,193],"signalling":[36],"may":[38,408],"lead":[39],"mutation,":[41],"or":[42,80],"death.":[44],"purpose":[46,246],"this":[48,98,115,245,390,398],"work":[49,391],"was":[50,128,146,208,218],"mathematical":[55,92],"in":[60,97,130,188,200,348,363,389,434],"mammalian":[61],"cells.":[62],"is":[66,100,110],"based":[67,140],"on":[68,141,170],"biochemical":[69,137],"action":[70,145],"proteins":[73],"examine":[75],"the":[76,108,122,150,171,183,189,198,221,227,253,264,276,312,330,335,338,349,364,367,380,383,440,459,491,520,554],"hypotheses":[77],"regarding":[78],"two":[79],"more":[81],"components":[82],"double":[84,341],"strand":[85,342],"break":[86],"(DSB)":[87],"kinetics.":[89],"proposed":[96,248],"thesis":[99],"part":[101],"bottom-up":[104],"approach":[105,116],"assumes":[107],"complex":[112,339],"system.":[113],"In":[114],"induces":[118],"damage,":[120],"perturbation":[127],"modelled":[129],"terms":[131,201],"activating":[133],"processes.":[135],"A":[136,528,547],"kinetic":[138],"method":[139,250],"law":[142],"mass":[144],"employed":[147],"pathways.":[152,326],"consists":[156],"set":[159],"nonlinear":[161],"differential":[162],"equations":[163],"calculates":[165],"explains":[167],"protein":[168,254],"activity":[169],"step":[173],"by":[174,238,281,500,524],"step.":[175],"takes":[178],"into":[179],"account":[180],"complexity":[181],"DSB,":[184,260],"topology":[185],"nucleus,":[191],"cycle.":[194],"solution":[196],"overall":[203],"kinetics":[204,232,274,351],"DSB":[206,236,279,353,361],"compared":[209,293],"pulsed-field":[211],"gel":[212],"electrophoresis":[213],"measurements.":[214],"integrated":[219],"track":[222],"structure":[223],"calculate":[226,263],"spectrum":[229],"for":[233,257,268,275,297,320,329,379,412,431,458,490,553],"every":[234,258],"individual":[235,259],"induced":[237,280],"monoenergetic":[239,285],"electrons,":[240],"ultrasoft":[242,288,305],"X-rays.":[243,306],"For":[244],"we":[247],"sample":[252],"actions":[256],"finally":[262],"total":[265],"time":[267],"specific":[270],"DSB.":[271],"DSB-repair":[273],"number":[277],"500":[282],"tracks":[283],"electrons":[286],"X-rays":[289],"were":[290],"calculated":[291],"results":[296,308,356],"cells":[298],"irradiated":[299],"AlK,":[301],"CK,":[302],"TiK":[304],"presented":[309],"here":[310],"form":[311],"first":[313,331],"example":[314],"modelling":[317],"calculations":[319],"NHEJ,":[321],"HR":[322],"MMEJ":[324],"results,":[328],"time,":[332],"quantitatively":[333],"confirm":[334,358],"hypothesis":[336],"type":[340],"breaks":[343],"play":[344],"major":[346],"role":[347],"slow":[350],"also":[357],"simple":[360],"located":[362],"heterocromatin":[365],"delay":[366],"process":[369],"due":[370],"series":[373],"processes":[375],"are":[377],"required":[378],"relaxation":[381],"heterochromatin.":[384],"established":[388],"unique":[394],"continue":[397],"study":[399],"responses":[402],"further":[405],"downstream":[406],"important":[410],"implications":[411],"human":[413],"risk":[414],"estimation":[415],"radiotherapy.":[417],"List":[418],"scientific":[420],"papers":[421],"I.":[422],"Taleei":[423,448,474,513,540],"R,":[424,449,475,514,541],"Nikjoo":[425,450,481,515,544],"H.":[426,451,482,516,545],"(2013).":[427,452,483],"Biochemical":[428],"DSB-Repair":[429],"Model":[430,549],"Mammalian":[432],"Cells":[433],"G1":[435],"Early":[437],"Phases":[438],"Cell":[441],"Cycle.":[442],"Mutation":[443],"Research.":[444,469,508],"[Accepted]":[445],"https://pubmed.ncbi.nlm.nih.gov/23792210":[446],"II.":[447],"Nonhomologous":[454,485],"End-Joining":[455,486],"(NHEJ)":[456,487],"Pathway":[457],"Repair":[460,492,518,555],"Double-Strand":[463,494,521,558],"Breaks:":[464,495],"I-A":[465],"Mathematical":[466],"Model.":[467],"Radiation":[468,507,534,560],"179:":[470,509],"530-9.":[471],"https://doi.org/10.1667/RR3123.1":[472],"III.":[473],"Girard":[476],"P":[477],"M,":[478,543],"Sankaranarayanan":[479],"K,":[480],"Mathematica":[488],"lModel":[489],"II-Application":[496],"Damage":[498],"Induced":[499,523],"Ultrasoft":[501],"X-Rays":[502],"Low":[504,525],"Energy":[505,526],"Electrons.":[506],"540-8.":[510],"https://doi.org/10.1667/RR3124.1":[511],"IV.":[512],"(2012).":[517],"Breaks":[522],"Electrons:":[527],"Modelling":[529],"Approach.":[530],"International":[531],"Journal":[532],"Biology.":[535],"88(12):":[536],"948-53.":[537],"https://doi.org/10.3109/09553002.2012.695098":[538],"V.":[539],"Weinfeld":[542],"(2011).":[546],"Kinetic":[548],"Single-Strand":[551],"Annealing":[552],"Breaks.":[559],"Protection":[561],"Dosimetry.":[562],"143(2-4):":[563],"191-5.":[564],"https://doi.org/10.1093/rpd/ncq535":[565]},"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2014,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}
