{"id":"https://openalex.org/W2104377342","doi":"https://doi.org/10.1109/iembs.1999.802442","title":"Nitric oxide monitoring in hippocampal brain slices","display_name":"Nitric oxide monitoring in hippocampal brain slices","publication_year":2003,"publication_date":"2003-01-20","ids":{"openalex":"https://openalex.org/W2104377342","doi":"https://doi.org/10.1109/iembs.1999.802442","mag":"2104377342"},"language":"en","primary_location":{"id":"doi:10.1109/iembs.1999.802442","doi":"https://doi.org/10.1109/iembs.1999.802442","is_oa":false,"landing_page_url":"https://doi.org/10.1109/iembs.1999.802442","pdf_url":null,"source":{"id":"https://openalex.org/S4363608786","display_name":"Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)","issn_l":"2375-7477","issn":["2375-7477"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["doyens","jufo-1","ki-jl-1","medline","russia-white-list-3"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"conference"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the First Joint BMES/EMBS Conference. 1999 IEEE Engineering in Medicine and Biology 21st Annual Conference and the 1999 Annual Fall Meeting of the Biomedical Engineering Society (Cat. No.99CH37015)","raw_type":"proceedings-article"},"volume":null,"type":"conference-paper","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5113644506","display_name":"Rajagopalan Rangarajan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I2799853436","display_name":"Johns Hopkins Medicine","ror":"https://ror.org/037zgn354","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"R. Rangarajan","raw_affiliation_strings":["Biomedical Engineering, Johns Hopkins School of Medicine, Baltimore, MD, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomedical Engineering, Johns Hopkins School of Medicine, Baltimore, MD, USA","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I2799853436"]}]},{"author_position":"middle","author":{"id":null,"display_name":"L.J. Johnson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I2799853436","display_name":"Johns Hopkins Medicine","ror":"https://ror.org/037zgn354","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"L.J. Johnson","raw_affiliation_strings":["Biomedical Engineering, Johns Hopkins School of Medicine, Baltimore, MD, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomedical Engineering, Johns Hopkins School of Medicine, Baltimore, MD, USA","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I2799853436"]}]},{"author_position":"middle","author":{"id":null,"display_name":"N.C. Yang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I2799853436","display_name":"Johns Hopkins Medicine","ror":"https://ror.org/037zgn354","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"N.C. Yang","raw_affiliation_strings":["Biomedical Engineering, Johns Hopkins School of Medicine, Baltimore, MD, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomedical Engineering, Johns Hopkins School of Medicine, Baltimore, MD, USA","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I2799853436"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5088964967","display_name":"Nitish V. Thakor","orcid":"https://orcid.org/0000-0002-9981-9395","observed_orcids":["https://orcid.org/0000-0002-9981-9395"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I2799853436","display_name":"Johns Hopkins Medicine","ror":"https://ror.org/037zgn354","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"N.V. Thakor","raw_affiliation_strings":["Biomedical Engineering, Johns Hopkins School of Medicine, Baltimore, MD, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomedical Engineering, Johns Hopkins School of Medicine, Baltimore, MD, USA","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I2799853436"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.11394558,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"1","issue":null,"first_page":"365","last_page":"365"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.9932000041007996,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.9932000041007996,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10155","display_name":"Nitric Oxide and Endothelin Effects","score":0.002199999988079071,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12770","display_name":"Amino Acid Enzymes and Metabolism","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/nitric-oxide","display_name":"nitric oxide","score":0.9309999942779541},{"id":"https://openalex.org/keywords/nmda-receptor","display_name":"NMDA receptor","score":0.7940000295639038},{"id":"https://openalex.org/keywords/excitotoxicity","display_name":"excitotoxicity","score":0.968999981880188},{"id":"https://openalex.org/keywords/hippocampus","display_name":"hippocampus","score":0.8180000185966492},{"id":"https://openalex.org/keywords/ca1","display_name":"CA1","score":0.9100000262260437},{"id":"https://openalex.org/keywords/ca3","display_name":"CA3","score":1.0},{"id":"https://openalex.org/keywords/dentate-gyrus","display_name":"dentate gyrus","score":0.9980000257492065},{"id":"https://openalex.org/keywords/hippocampal-subfields","display_name":"hippocampal subfields","score":0.7570000290870667},{"id":"https://openalex.org/keywords/nitric-oxide-production","display_name":"nitric oxide production","score":0.6959999799728394}],"concepts":[{"id":"https://openalex.org/C67018056","wikidata":"https://www.wikidata.org/wiki/Q414896","display_name":"NMDA receptor","level":3,"score":0.9349706172943115},{"id":"https://openalex.org/C148762608","wikidata":"https://www.wikidata.org/wiki/Q3748185","display_name":"Hippocampal formation","level":2,"score":0.8312543630599976},{"id":"https://openalex.org/C2776464000","wikidata":"https://www.wikidata.org/wiki/Q545787","display_name":"Dentate gyrus","level":3,"score":0.8212690353393555},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.6892077922821045},{"id":"https://openalex.org/C519581460","wikidata":"https://www.wikidata.org/wiki/Q207843","display_name":"Nitric oxide","level":2,"score":0.6789683103561401},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5205832123756409},{"id":"https://openalex.org/C61174792","wikidata":"https://www.wikidata.org/wiki/Q420510","display_name":"Glutamate receptor","level":3,"score":0.4835509955883026},{"id":"https://openalex.org/C2781161787","wikidata":"https://www.wikidata.org/wiki/Q48360","display_name":"Hippocampus","level":2,"score":0.4442490041255951},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.3961680829524994},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2743139863014221},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.14504167437553406},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/iembs.1999.802442","doi":"https://doi.org/10.1109/iembs.1999.802442","is_oa":false,"landing_page_url":"https://doi.org/10.1109/iembs.1999.802442","pdf_url":null,"source":{"id":"https://openalex.org/S4363608786","display_name":"Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)","issn_l":"2375-7477","issn":["2375-7477"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["doyens","jufo-1","ki-jl-1","medline","russia-white-list-3"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"conference"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the First Joint BMES/EMBS Conference. 1999 IEEE Engineering in Medicine and Biology 21st Annual Conference and the 1999 Annual Fall Meeting of the Biomedical Engineering Society (Cat. No.99CH37015)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320306250","display_name":"Battelle","ror":"https://ror.org/01h5tnr73"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":4,"referenced_works":["https://openalex.org/W1986100628","https://openalex.org/W1988726352","https://openalex.org/W2009083552","https://openalex.org/W2085416235"],"related_works":["https://openalex.org/W2089955188","https://openalex.org/W2268486950","https://openalex.org/W2097387367","https://openalex.org/W2033080453","https://openalex.org/W7097457594","https://openalex.org/W1552073493","https://openalex.org/W1974131520","https://openalex.org/W2010478333","https://openalex.org/W1991125142","https://openalex.org/W2171438740"],"abstract_inverted_index":{"Nitric":[0],"Oxide":[1],"(NO)":[2],"is":[3,26,74],"known":[4],"to":[5,12,22,46,81],"mediate":[6],"the":[7,32,36,50,55,60,68],"excitotoxic":[8],"injury":[9],"caused":[10],"due":[11],"overactivation":[13],"of":[14,52],"N-Methyl-D-Aspartate":[15],"(NMDA)":[16],"receptors.":[17],"NO":[18,69],"production":[19,70],"in":[20,28,57,62,71],"response":[21,53],"NMDA":[23,47],"receptor":[24],"activation":[25],"studied":[27],"three":[29,41],"hippocampal":[30],"subregions:":[31],"CA1,":[33],"CA3":[34],"and":[35,59,76],"Dentate":[37],"Gyrus":[38],"(DG).":[39],"These":[40],"regions":[42,73],"are":[43],"differentially":[44],"sensitive":[45],"toxicity,":[48],"with":[49,78],"degree":[51],"being":[54],"highest":[56],"CA1":[58],"lowest":[61],"DG.":[63],"The":[64],"results":[65],"show":[66],"that":[67],"these":[72],"different":[75],"consistent":[77],"their":[79],"sensitivity":[80],"NMDA.":[82]},"counts_by_year":[],"updated_date":"2026-10-26T11:51:55.731654","created_date":"2016-06-24T00:00:00"}