{"id":"https://openalex.org/W2104259072","doi":"https://doi.org/10.1002/jps.24137","title":"Amorphous Stabilization and Dissolution Enhancement of Amorphous Ternary Solid Dispersions: Combination of Polymers Showing Drug\u2013Polymer Interaction for Synergistic Effects","display_name":"Amorphous Stabilization and Dissolution Enhancement of Amorphous Ternary Solid Dispersions: Combination of Polymers Showing Drug\u2013Polymer Interaction for Synergistic Effects","publication_year":2014,"publication_date":"2014-09-05","ids":{"openalex":"https://openalex.org/W2104259072","doi":"https://doi.org/10.1002/jps.24137","mag":"2104259072","pmid":"https://pubmed.ncbi.nlm.nih.gov/25196860"},"language":"en","primary_location":{"id":"doi:10.1002/jps.24137","doi":"https://doi.org/10.1002/jps.24137","is_oa":false,"landing_page_url":"https://doi.org/10.1002/jps.24137","pdf_url":null,"source":{"id":"https://openalex.org/S130661733","display_name":"Journal of Pharmaceutical Sciences","issn_l":"0022-3549","issn":["0022-3549","1520-6017"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Pharmaceutical Sciences","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5090150854","display_name":"Dev Prasad","orcid":"https://orcid.org/0009-0008-4463-5514","observed_orcids":["https://orcid.org/0009-0008-4463-5514"]},"institutions":[{"id":"https://openalex.org/I165817395","display_name":"Massachusetts College of Pharmacy and Health Sciences","ror":"https://ror.org/02fvywg07","country_code":"US","type":"education","lineage":["https://openalex.org/I165817395"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dev Prasad","raw_affiliation_strings":["School of Pharmacy, MCPHS University-Boston, Boston, Massachusetts 02115"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Pharmacy, MCPHS University-Boston, Boston, Massachusetts 02115","institution_ids":["https://openalex.org/I165817395"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045952978","display_name":"Harsh Chauhan","orcid":"https://orcid.org/0009-0007-2632-1055","observed_orcids":["https://orcid.org/0009-0007-2632-1055"]},"institutions":[{"id":"https://openalex.org/I114493937","display_name":"Creighton University","ror":"https://ror.org/05wf30g94","country_code":"US","type":"education","lineage":["https://openalex.org/I114493937"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Harsh Chauhan","raw_affiliation_strings":["School of Pharmacy and Health Professions, Creighton University, Omaha, Nebraska 68178"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Pharmacy and Health Professions, Creighton University, Omaha, Nebraska 68178","institution_ids":["https://openalex.org/I114493937"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5047343551","display_name":"Eman Atef","orcid":"https://orcid.org/0000-0002-5252-7977","observed_orcids":["https://orcid.org/0000-0002-5252-7977"]},"institutions":[{"id":"https://openalex.org/I165817395","display_name":"Massachusetts College of Pharmacy and Health Sciences","ror":"https://ror.org/02fvywg07","country_code":"US","type":"education","lineage":["https://openalex.org/I165817395"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Eman Atef","raw_affiliation_strings":["School of Pharmacy, MCPHS University-Boston, Boston, Massachusetts 02115. Electronic address: eman.atef@mcphs.edu","School of Pharmacy, MCPHS University-Boston, Boston, Massachusetts 02115"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Pharmacy, MCPHS University-Boston, Boston, Massachusetts 02115. Electronic address: eman.atef@mcphs.edu","institution_ids":["https://openalex.org/I165817395"]},{"raw_affiliation_string":"School of Pharmacy, MCPHS University-Boston, Boston, Massachusetts 02115","institution_ids":["https://openalex.org/I165817395"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5047343551"],"corresponding_institution_ids":["https://openalex.org/I165817395"],"apc_list":{"value":3620,"currency":"USD","value_usd":3620},"apc_paid":null,"fwci":7.2253,"has_fulltext":false,"cited_by_count":120,"citation_normalized_percentile":{"value":0.98827129,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":93,"max":100},"biblio":{"volume":"103","issue":"11","first_page":"3511","last_page":"3523"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10256","display_name":"Drug Solubulity and Delivery Systems","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10256","display_name":"Drug Solubulity and Delivery Systems","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11881","display_name":"Crystallization and Solubility Studies","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10920","display_name":"Advanced Drug Delivery Systems","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/amorphous-solid-dispersions","display_name":"amorphous solid dispersions","score":0.8450000286102295},{"id":"https://openalex.org/keywords/ternary-solid-dispersion","display_name":"ternary solid dispersion","score":0.9670000076293945},{"id":"https://openalex.org/keywords/indomethacin","display_name":"indomethacin","score":0.9819999933242798},{"id":"https://openalex.org/keywords/amorphous-drug-stabilization","display_name":"amorphous drug stabilization","score":0.7649999856948853},{"id":"https://openalex.org/keywords/dissolution-enhancement","display_name":"dissolution enhancement","score":0.9020000100135803},{"id":"https://openalex.org/keywords/drug-polymer-interactions","display_name":"drug-polymer interactions","score":0.9110000133514404},{"id":"https://openalex.org/keywords/eudragit-e100","display_name":"Eudragit E100","score":0.9789999723434448},{"id":"https://openalex.org/keywords/polymer-blends","display_name":"polymer blends","score":0.5090000033378601},{"id":"https://openalex.org/keywords/drug-polymer-miscibility","display_name":"drug-polymer miscibility","score":0.9039999842643738},{"id":"https://openalex.org/keywords/melting-point-depression","display_name":"melting point depression","score":0.8479999899864197},{"id":"https://openalex.org/keywords/solvent-evaporation","display_name":"solvent evaporation","score":0.6050000190734863}],"concepts":[{"id":"https://openalex.org/C56052488","wikidata":"https://www.wikidata.org/wiki/Q103382","display_name":"Amorphous solid","level":2,"score":0.8711711764335632},{"id":"https://openalex.org/C88380143","wikidata":"https://www.wikidata.org/wiki/Q416674","display_name":"Dissolution","level":2,"score":0.7735658288002014},{"id":"https://openalex.org/C64452783","wikidata":"https://www.wikidata.org/wiki/Q1524945","display_name":"Ternary operation","level":2,"score":0.7628461122512817},{"id":"https://openalex.org/C521977710","wikidata":"https://www.wikidata.org/wiki/Q81163","display_name":"Polymer","level":2,"score":0.7233257293701172},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.5480993390083313},{"id":"https://openalex.org/C42360764","wikidata":"https://www.wikidata.org/wiki/Q83588","display_name":"Chemical engineering","level":1,"score":0.5345311164855957},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.30586904287338257},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.24170604348182678},{"id":"https://openalex.org/C159985019","wikidata":"https://www.wikidata.org/wiki/Q181790","display_name":"Composite material","level":1,"score":0.1037837564945221},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.0},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000179","descriptor_name":"Acrylates","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D002626","descriptor_name":"Chemistry, Pharmaceutical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004337","descriptor_name":"Drug Carriers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004355","descriptor_name":"Drug Stability","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007213","descriptor_name":"Indomethacin","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D007700","descriptor_name":"Kinetics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008956","descriptor_name":"Models, Chemical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011108","descriptor_name":"Polymers","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D011205","descriptor_name":"Povidone","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D012995","descriptor_name":"Solubility","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013055","descriptor_name":"Spectrophotometry, Infrared","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013059","descriptor_name":"Spectrum Analysis, Raman","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013678","descriptor_name":"Technology, Pharmaceutical","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D044366","descriptor_name":"Transition Temperature","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1002/jps.24137","doi":"https://doi.org/10.1002/jps.24137","is_oa":false,"landing_page_url":"https://doi.org/10.1002/jps.24137","pdf_url":null,"source":{"id":"https://openalex.org/S130661733","display_name":"Journal of Pharmaceutical Sciences","issn_l":"0022-3549","issn":["0022-3549","1520-6017"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Pharmaceutical Sciences","raw_type":"journal-article"},{"id":"pmid:25196860","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25196860","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of pharmaceutical sciences","raw_type":"Comparative Study"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.5683000087738037,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":42,"referenced_works":["https://openalex.org/W252847268","https://openalex.org/W1205462427","https://openalex.org/W1543696264","https://openalex.org/W1859431889","https://openalex.org/W1963852040","https://openalex.org/W1966423358","https://openalex.org/W1967935934","https://openalex.org/W1973791844","https://openalex.org/W1974586971","https://openalex.org/W1985569871","https://openalex.org/W1986251008","https://openalex.org/W1995015657","https://openalex.org/W1998580244","https://openalex.org/W1998647396","https://openalex.org/W2005893499","https://openalex.org/W2013133034","https://openalex.org/W2015025440","https://openalex.org/W2020068592","https://openalex.org/W2029846748","https://openalex.org/W2033296599","https://openalex.org/W2039829919","https://openalex.org/W2040432233","https://openalex.org/W2044146593","https://openalex.org/W2045465776","https://openalex.org/W2050648235","https://openalex.org/W2067777829","https://openalex.org/W2069057888","https://openalex.org/W2077594374","https://openalex.org/W2077886122","https://openalex.org/W2078814811","https://openalex.org/W2080575627","https://openalex.org/W2091417768","https://openalex.org/W2091818949","https://openalex.org/W2093248776","https://openalex.org/W2096730890","https://openalex.org/W2123496836","https://openalex.org/W2143076068","https://openalex.org/W2156829937","https://openalex.org/W2161839755","https://openalex.org/W2468683252","https://openalex.org/W4210982805","https://openalex.org/W4285719527"],"related_works":["https://openalex.org/W4390671917","https://openalex.org/W3144821393","https://openalex.org/W7208792755","https://openalex.org/W4284675931","https://openalex.org/W2132217981","https://openalex.org/W4404167821","https://openalex.org/W2544584945","https://openalex.org/W72380014","https://openalex.org/W1985569871","https://openalex.org/W2039036418"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":10},{"year":2023,"cited_by_count":12},{"year":2022,"cited_by_count":6},{"year":2021,"cited_by_count":13},{"year":2020,"cited_by_count":11},{"year":2019,"cited_by_count":18},{"year":2018,"cited_by_count":11},{"year":2017,"cited_by_count":15},{"year":2016,"cited_by_count":8},{"year":2015,"cited_by_count":11}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}