{"id":"https://openalex.org/W2104124407","doi":null,"title":"Metodutveckling f\u00f6r analys av serglycinuttrycket i blodet hos hundar","display_name":"Metodutveckling f\u00f6r analys av serglycinuttrycket i blodet hos hundar","publication_year":2008,"publication_date":"2008-03-31","ids":{"openalex":"https://openalex.org/W2104124407","mag":"2104124407"},"language":"sv","primary_location":{"id":"pmh:oai:stud.epsilon.slu.se:12083","doi":null,"is_oa":false,"landing_page_url":"https://stud.epsilon.slu.se/12083/","pdf_url":null,"source":{"id":"https://openalex.org/S4306401562","display_name":"Epsilon Archive for Student Projects (University of Southampton)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I43439940","host_organization_name":"University of Southampton","host_organization_lineage":["https://openalex.org/I43439940"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"L3"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5064279023","display_name":"Boel Sandros","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Boel Sandros","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5064279023"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11149","display_name":"Veterinary Oncology Research","score":0.49900001287460327,"subfield":{"id":"https://openalex.org/subfields/3404","display_name":"Small Animals"},"field":{"id":"https://openalex.org/fields/34","display_name":"Veterinary"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11149","display_name":"Veterinary Oncology Research","score":0.49900001287460327,"subfield":{"id":"https://openalex.org/subfields/3404","display_name":"Small Animals"},"field":{"id":"https://openalex.org/fields/34","display_name":"Veterinary"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11970","display_name":"Molecular Biology Techniques and Applications","score":0.4912000000476837,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11580","display_name":"Veterinary Medicine and Surgery","score":0.002199999988079071,"subfield":{"id":"https://openalex.org/subfields/3404","display_name":"Small Animals"},"field":{"id":"https://openalex.org/fields/34","display_name":"Veterinary"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/serglycin","display_name":"serglycin","score":0.984000027179718},{"id":"https://openalex.org/keywords/gene-expression-quantification","display_name":"gene expression quantification","score":0.6859999895095825},{"id":"https://openalex.org/keywords/canine-blood","display_name":"canine blood","score":0.7279999852180481},{"id":"https://openalex.org/keywords/dogs","display_name":"dogs","score":0.906000018119812},{"id":"https://openalex.org/keywords/mast-cell-tumor","display_name":"mastocytoma","score":0.8330000042915344},{"id":"https://openalex.org/keywords/tumor-markers","display_name":"tumor markers","score":0.722000002861023},{"id":"https://openalex.org/keywords/acute-myeloid-leukemia","display_name":"acute myeloid leukemia","score":0.9440000057220459},{"id":"https://openalex.org/keywords/primer-design","display_name":"primer design","score":0.921999990940094},{"id":"https://openalex.org/keywords/dog-genome","display_name":"dog genome","score":0.421999990940094}],"concepts":[{"id":"https://openalex.org/C48023723","wikidata":"https://www.wikidata.org/wiki/Q856198","display_name":"Real-time polymerase chain reaction","level":3,"score":0.5333442687988281},{"id":"https://openalex.org/C2778729363","wikidata":"https://www.wikidata.org/wiki/Q11688946","display_name":"Myeloid leukemia","level":2,"score":0.4969692528247833},{"id":"https://openalex.org/C2777563447","wikidata":"https://www.wikidata.org/wiki/Q7243397","display_name":"Primer (cosmetics)","level":2,"score":0.47925639152526855},{"id":"https://openalex.org/C109159458","wikidata":"https://www.wikidata.org/wiki/Q919283","display_name":"Haematopoiesis","level":3,"score":0.4680590033531189},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.4371867775917053},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4292062222957611},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.41850125789642334},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.4064286947250366},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.36377182602882385},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.34748998284339905},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.2266734540462494},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.21351265907287598},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.11470317840576172},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:stud.epsilon.slu.se:12083","doi":null,"is_oa":false,"landing_page_url":"https://stud.epsilon.slu.se/12083/","pdf_url":null,"source":{"id":"https://openalex.org/S4306401562","display_name":"Epsilon Archive for Student Projects (University of Southampton)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I43439940","host_organization_name":"University of Southampton","host_organization_lineage":["https://openalex.org/I43439940"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"L3"},{"id":"mag:2104124407","doi":null,"is_oa":false,"landing_page_url":"http://epsilon.slu.se/10736420.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.8048999905586243,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":8,"referenced_works":["https://openalex.org/W1975996690","https://openalex.org/W2029383635","https://openalex.org/W2081016602","https://openalex.org/W2108794386","https://openalex.org/W2122749842","https://openalex.org/W2132111331","https://openalex.org/W2139173091","https://openalex.org/W2768776045"],"related_works":["https://openalex.org/W2906492185","https://openalex.org/W2954238462","https://openalex.org/W7062183620","https://openalex.org/W1531293548","https://openalex.org/W2021617407","https://openalex.org/W2139339291","https://openalex.org/W1895614542","https://openalex.org/W7073664940","https://openalex.org/W2758267622","https://openalex.org/W4280624745"],"abstract_inverted_index":{"The":[0,121,220],"development":[1],"of":[2,11,29,32,46,65,80,119,123,143,168,180,188,229],"quantitative,":[3],"real-time":[4],"PCR":[5],"(qPCR)":[6],"combined":[7],"with":[8],"the":[9,12,30,48,74,93,116,207,211,236],"mapping":[10],"canine":[13,192],"genome":[14],"opens":[15],"new":[16],"possibilities":[17],"in":[18,40,98,125,137,191,227,232],"veterinary":[19],"medicine.":[20],"This":[21],"method":[22],"provides":[23],"a":[24,33,37,52,89,154,171,186,197],"quick":[25],"and":[26,42,60,162,215,239],"accurate":[27],"quantification":[28],"expression":[31,50,122,190],"specific":[34],"gene":[35,49],"at":[36],"given":[38],"point":[39,199],"time":[41],"thereby":[43],"also":[44],"information":[45],"how":[47,169],"for":[51,71,92,115,156,200,210],"certain":[53],"protein":[54,75,79],"is":[55,67,105,173,183,223],"influenced":[56],"by":[57,107],"various":[58],"conditions":[59],"diseases.":[61],"One":[62],"possible":[63],"area":[64],"application":[66],"identifying":[68],"bio":[69],"markers":[70],"cancer.":[72],"Recently":[73],"serglycin":[76,124,149,189],"(the":[77],"core":[78],"an":[81],"intracellular":[82],"proteoglycan)":[83],"was":[84],"found":[85],"to":[86,128,145,159,175,184,194,234],"act":[87],"as":[88,153,164,166,196,206],"selective":[90],"marker":[91,155],"disease":[94],"acute":[95],"myeloid":[96],"leukemia":[97],"humans":[99],"(Niemann":[100],"et":[101],"al,":[102],"2007).":[103],"Serglycin":[104],"produced":[106],"most":[108],"hematopoietic":[109],"cells,":[110],"although":[111,225],"mast":[112,132],"cells":[113],"account":[114],"largest":[117],"amount":[118],"serglycin.":[120],"dogs":[126],"remains":[127],"be":[129,142,151],"explored.":[130],"As":[131],"cell":[133],"tumours":[134],"are":[135],"common":[136],"this":[138,181],"species,":[139],"it":[140],"would":[141],"interest":[144],"find":[146],"out":[147],"whether":[148],"can":[150],"used":[152],"these":[157],"tumours,":[158],"facilitate":[160],"diagnosis":[161],"prognosis":[163],"well":[165,170],"evaluation":[167],"patient":[172],"responding":[174],"treatment.":[176],"\\n":[177],"\\nThe":[178],"aim":[179],"study":[182],"develop":[185],"qPCR-analysis":[187],"blood,":[193],"serve":[195],"starting":[198],"further":[201,230],"research.":[202],"Several":[203],"parameters,":[204],"such":[205],"optimum":[208],"temperature":[209],"PCR-reaction,":[212],"primer":[213],"design":[214],"DNA-concentration,":[216],"have":[217],"been":[218],"established.":[219],"resulting":[221],"PCR-analysis":[222],"functioning,":[224],"still":[226],"need":[228],"modifications":[231],"order":[233],"achieve":[235],"desired":[237],"efficiency":[238],"reproducibility.":[240]},"counts_by_year":[],"updated_date":"2026-10-27T15:51:10.671819","created_date":"2016-06-24T00:00:00"}