{"id":"https://openalex.org/W2104090580","doi":"https://doi.org/10.1176/appi.neuropsych.17.4.465","title":"Association of COMT Val158Met Genotype With Executive Functioning Following Traumatic Brain Injury","display_name":"Association of COMT Val158Met Genotype With Executive Functioning Following Traumatic Brain Injury","publication_year":2005,"publication_date":"2005-11-01","ids":{"openalex":"https://openalex.org/W2104090580","doi":"https://doi.org/10.1176/appi.neuropsych.17.4.465","mag":"2104090580","pmid":"https://pubmed.ncbi.nlm.nih.gov/16387984"},"language":"en","primary_location":{"id":"doi:10.1176/appi.neuropsych.17.4.465","doi":"https://doi.org/10.1176/appi.neuropsych.17.4.465","is_oa":false,"landing_page_url":"https://doi.org/10.1176/appi.neuropsych.17.4.465","pdf_url":null,"source":{"id":"https://openalex.org/S50352613","display_name":"Journal of Neuropsychiatry","issn_l":"0895-0172","issn":["0895-0172","1545-7222"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4320800570","host_organization_name":"American Psychiatric Association Publishing","host_organization_lineage":["https://openalex.org/P4320800570","https://openalex.org/P4310316602"],"host_organization_lineage_names":["American Psychiatric Association Publishing","American Psychiatric Association"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Neuropsychiatry","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://neuro.psychiatryonline.org/doi/pdf/10.1176/jnp.17.4.465","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5021708761","display_name":"Robert H. Lipsky","orcid":"https://orcid.org/0000-0001-7753-1473","observed_orcids":["https://orcid.org/0000-0001-7753-1473"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I148314036","display_name":"Uniformed Services University of the Health Sciences","ror":"https://ror.org/04r3kq386","country_code":"US","type":"education","lineage":["https://openalex.org/I148314036"]},{"id":"https://openalex.org/I2800363604","display_name":"Walter Reed National Military Medical Center","ror":"https://ror.org/025cem651","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330347796","https://openalex.org/I2800250139","https://openalex.org/I2800363604","https://openalex.org/I2800386880"]},{"id":"https://openalex.org/I4210121815","display_name":"National Institute on Alcohol Abuse and Alcoholism","ror":"https://ror.org/02jzrsm59","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210121815"]},{"id":"https://openalex.org/I4405268472","display_name":"Defense and Veterans Brain Injury Center","ror":"https://ror.org/01345ed13","country_code":"US","type":"government","lineage":["https://openalex.org/I4405268472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert H. Lipsky","raw_affiliation_strings":["Received December 12, 2003; revised June 17, 2004; accepted June 24, 2004. From the Laboratory of Neurogenetics, National Institute on Alcohol Abuse and Alcoholism, NIH, Rockville, Maryland; the Defense and Veterans Brain Injury Center, Departments of Neurology and Neurosurgery, Walter Reed Army Medical Center, Washington, DC; the Uniformed Services University of Health Sciences, Bethesda, Maryland. Address correspondence to Dr. Warden, Defense and Veterans Brain Injury Center, Walter Reed Army Medical"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Received December 12, 2003; revised June 17, 2004; accepted June 24, 2004. From the Laboratory of Neurogenetics, National Institute on Alcohol Abuse and Alcoholism, NIH, Rockville, Maryland; the Defense and Veterans Brain Injury Center, Departments of Neurology and Neurosurgery, Walter Reed Army Medical Center, Washington, DC; the Uniformed Services University of Health Sciences, Bethesda, Maryland. Address correspondence to Dr. Warden, Defense and Veterans Brain Injury Center, Walter Reed Army Medical","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I148314036","https://openalex.org/I2800363604","https://openalex.org/I4210121815","https://openalex.org/I4405268472"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054779149","display_name":"Molly B. Sparling","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I148314036","display_name":"Uniformed Services University of the Health Sciences","ror":"https://ror.org/04r3kq386","country_code":"US","type":"education","lineage":["https://openalex.org/I148314036"]},{"id":"https://openalex.org/I2800363604","display_name":"Walter Reed National Military Medical Center","ror":"https://ror.org/025cem651","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330347796","https://openalex.org/I2800250139","https://openalex.org/I2800363604","https://openalex.org/I2800386880"]},{"id":"https://openalex.org/I4210121815","display_name":"National Institute on Alcohol Abuse and Alcoholism","ror":"https://ror.org/02jzrsm59","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210121815"]},{"id":"https://openalex.org/I4405268472","display_name":"Defense and Veterans Brain Injury Center","ror":"https://ror.org/01345ed13","country_code":"US","type":"government","lineage":["https://openalex.org/I4405268472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Molly B. Sparling","raw_affiliation_strings":["Received December 12, 2003; revised June 17, 2004; accepted June 24, 2004. From the Laboratory of Neurogenetics, National Institute on Alcohol Abuse and Alcoholism, NIH, Rockville, Maryland; the Defense and Veterans Brain Injury Center, Departments of Neurology and Neurosurgery, Walter Reed Army Medical Center, Washington, DC; the Uniformed Services University of Health Sciences, Bethesda, Maryland. Address correspondence to Dr. Warden, Defense and Veterans Brain Injury Center, Walter Reed Army Medical","Defense and Vet-erans Brain Injury Center, Walter Reed Army Medical Center, P.O. Box 59181, Washington, DC 20012;","Uniformed Services University of Health Sciences, Bethesda, Maryland","Walter Reed Army Medical Center, Washington, DC; the"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Received December 12, 2003; revised June 17, 2004; accepted June 24, 2004. From the Laboratory of Neurogenetics, National Institute on Alcohol Abuse and Alcoholism, NIH, Rockville, Maryland; the Defense and Veterans Brain Injury Center, Departments of Neurology and Neurosurgery, Walter Reed Army Medical Center, Washington, DC; the Uniformed Services University of Health Sciences, Bethesda, Maryland. Address correspondence to Dr. Warden, Defense and Veterans Brain Injury Center, Walter Reed Army Medical","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I148314036","https://openalex.org/I2800363604","https://openalex.org/I4210121815","https://openalex.org/I4405268472"]},{"raw_affiliation_string":"Defense and Vet-erans Brain Injury Center, Walter Reed Army Medical Center, P.O. Box 59181, Washington, DC 20012;","institution_ids":["https://openalex.org/I2800363604"]},{"raw_affiliation_string":"Uniformed Services University of Health Sciences, Bethesda, Maryland","institution_ids":["https://openalex.org/I148314036"]},{"raw_affiliation_string":"Walter Reed Army Medical Center, Washington, DC; the","institution_ids":["https://openalex.org/I2800363604"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5104012093","display_name":"Laurie M. Ryan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I148314036","display_name":"Uniformed Services University of the Health Sciences","ror":"https://ror.org/04r3kq386","country_code":"US","type":"education","lineage":["https://openalex.org/I148314036"]},{"id":"https://openalex.org/I2800363604","display_name":"Walter Reed National Military Medical Center","ror":"https://ror.org/025cem651","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330347796","https://openalex.org/I2800250139","https://openalex.org/I2800363604","https://openalex.org/I2800386880"]},{"id":"https://openalex.org/I4210121815","display_name":"National Institute on Alcohol Abuse and Alcoholism","ror":"https://ror.org/02jzrsm59","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210121815"]},{"id":"https://openalex.org/I4405268472","display_name":"Defense and Veterans Brain Injury Center","ror":"https://ror.org/01345ed13","country_code":"US","type":"government","lineage":["https://openalex.org/I4405268472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Laurie M. Ryan","raw_affiliation_strings":["Received December 12, 2003; revised June 17, 2004; accepted June 24, 2004. From the Laboratory of Neurogenetics, National Institute on Alcohol Abuse and Alcoholism, NIH, Rockville, Maryland; the Defense and Veterans Brain Injury Center, Departments of Neurology and Neurosurgery, Walter Reed Army Medical Center, Washington, DC; the Uniformed Services University of Health Sciences, Bethesda, Maryland. Address correspondence to Dr. Warden, Defense and Veterans Brain Injury Center, Walter Reed Army Medical"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Received December 12, 2003; revised June 17, 2004; accepted June 24, 2004. From the Laboratory of Neurogenetics, National Institute on Alcohol Abuse and Alcoholism, NIH, Rockville, Maryland; the Defense and Veterans Brain Injury Center, Departments of Neurology and Neurosurgery, Walter Reed Army Medical Center, Washington, DC; the Uniformed Services University of Health Sciences, Bethesda, Maryland. Address correspondence to Dr. Warden, Defense and Veterans Brain Injury Center, Walter Reed Army Medical","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I148314036","https://openalex.org/I2800363604","https://openalex.org/I4210121815","https://openalex.org/I4405268472"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055309934","display_name":"Ke Xu","orcid":"https://orcid.org/0000-0002-6472-7052","observed_orcids":["https://orcid.org/0000-0002-6472-7052"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I148314036","display_name":"Uniformed Services University of the Health Sciences","ror":"https://ror.org/04r3kq386","country_code":"US","type":"education","lineage":["https://openalex.org/I148314036"]},{"id":"https://openalex.org/I2800363604","display_name":"Walter Reed National Military Medical Center","ror":"https://ror.org/025cem651","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330347796","https://openalex.org/I2800250139","https://openalex.org/I2800363604","https://openalex.org/I2800386880"]},{"id":"https://openalex.org/I4210121815","display_name":"National Institute on Alcohol Abuse and Alcoholism","ror":"https://ror.org/02jzrsm59","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210121815"]},{"id":"https://openalex.org/I4405268472","display_name":"Defense and Veterans Brain Injury Center","ror":"https://ror.org/01345ed13","country_code":"US","type":"government","lineage":["https://openalex.org/I4405268472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ke Xu","raw_affiliation_strings":["Received December 12, 2003; revised June 17, 2004; accepted June 24, 2004. From the Laboratory of Neurogenetics, National Institute on Alcohol Abuse and Alcoholism, NIH, Rockville, Maryland; the Defense and Veterans Brain Injury Center, Departments of Neurology and Neurosurgery, Walter Reed Army Medical Center, Washington, DC; the Uniformed Services University of Health Sciences, Bethesda, Maryland. Address correspondence to Dr. Warden, Defense and Veterans Brain Injury Center, Walter Reed Army Medical"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Received December 12, 2003; revised June 17, 2004; accepted June 24, 2004. From the Laboratory of Neurogenetics, National Institute on Alcohol Abuse and Alcoholism, NIH, Rockville, Maryland; the Defense and Veterans Brain Injury Center, Departments of Neurology and Neurosurgery, Walter Reed Army Medical Center, Washington, DC; the Uniformed Services University of Health Sciences, Bethesda, Maryland. Address correspondence to Dr. Warden, Defense and Veterans Brain Injury Center, Walter Reed Army Medical","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I148314036","https://openalex.org/I2800363604","https://openalex.org/I4210121815","https://openalex.org/I4405268472"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Andres M. Salazar","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I148314036","display_name":"Uniformed Services University of the Health Sciences","ror":"https://ror.org/04r3kq386","country_code":"US","type":"education","lineage":["https://openalex.org/I148314036"]},{"id":"https://openalex.org/I2800363604","display_name":"Walter Reed National Military Medical Center","ror":"https://ror.org/025cem651","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330347796","https://openalex.org/I2800250139","https://openalex.org/I2800363604","https://openalex.org/I2800386880"]},{"id":"https://openalex.org/I4210121815","display_name":"National Institute on Alcohol Abuse and Alcoholism","ror":"https://ror.org/02jzrsm59","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210121815"]},{"id":"https://openalex.org/I4405268472","display_name":"Defense and Veterans Brain Injury Center","ror":"https://ror.org/01345ed13","country_code":"US","type":"government","lineage":["https://openalex.org/I4405268472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Andres M. Salazar","raw_affiliation_strings":["Received December 12, 2003; revised June 17, 2004; accepted June 24, 2004. From the Laboratory of Neurogenetics, National Institute on Alcohol Abuse and Alcoholism, NIH, Rockville, Maryland; the Defense and Veterans Brain Injury Center, Departments of Neurology and Neurosurgery, Walter Reed Army Medical Center, Washington, DC; the Uniformed Services University of Health Sciences, Bethesda, Maryland. Address correspondence to Dr. Warden, Defense and Veterans Brain Injury Center, Walter Reed Army Medical"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Received December 12, 2003; revised June 17, 2004; accepted June 24, 2004. From the Laboratory of Neurogenetics, National Institute on Alcohol Abuse and Alcoholism, NIH, Rockville, Maryland; the Defense and Veterans Brain Injury Center, Departments of Neurology and Neurosurgery, Walter Reed Army Medical Center, Washington, DC; the Uniformed Services University of Health Sciences, Bethesda, Maryland. Address correspondence to Dr. Warden, Defense and Veterans Brain Injury Center, Walter Reed Army Medical","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I148314036","https://openalex.org/I2800363604","https://openalex.org/I4210121815","https://openalex.org/I4405268472"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041766549","display_name":"David A Goldman","orcid":"https://orcid.org/0000-0002-1724-5405","observed_orcids":["https://orcid.org/0000-0002-1724-5405"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I148314036","display_name":"Uniformed Services University of the Health Sciences","ror":"https://ror.org/04r3kq386","country_code":"US","type":"education","lineage":["https://openalex.org/I148314036"]},{"id":"https://openalex.org/I2800363604","display_name":"Walter Reed National Military Medical Center","ror":"https://ror.org/025cem651","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330347796","https://openalex.org/I2800250139","https://openalex.org/I2800363604","https://openalex.org/I2800386880"]},{"id":"https://openalex.org/I4210121815","display_name":"National Institute on Alcohol Abuse and Alcoholism","ror":"https://ror.org/02jzrsm59","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210121815"]},{"id":"https://openalex.org/I4405268472","display_name":"Defense and Veterans Brain Injury Center","ror":"https://ror.org/01345ed13","country_code":"US","type":"government","lineage":["https://openalex.org/I4405268472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David Goldman","raw_affiliation_strings":["Received December 12, 2003; revised June 17, 2004; accepted June 24, 2004. From the Laboratory of Neurogenetics, National Institute on Alcohol Abuse and Alcoholism, NIH, Rockville, Maryland; the Defense and Veterans Brain Injury Center, Departments of Neurology and Neurosurgery, Walter Reed Army Medical Center, Washington, DC; the Uniformed Services University of Health Sciences, Bethesda, Maryland. Address correspondence to Dr. Warden, Defense and Veterans Brain Injury Center, Walter Reed Army Medical"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Received December 12, 2003; revised June 17, 2004; accepted June 24, 2004. From the Laboratory of Neurogenetics, National Institute on Alcohol Abuse and Alcoholism, NIH, Rockville, Maryland; the Defense and Veterans Brain Injury Center, Departments of Neurology and Neurosurgery, Walter Reed Army Medical Center, Washington, DC; the Uniformed Services University of Health Sciences, Bethesda, Maryland. Address correspondence to Dr. Warden, Defense and Veterans Brain Injury Center, Walter Reed Army Medical","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I148314036","https://openalex.org/I2800363604","https://openalex.org/I4210121815","https://openalex.org/I4405268472"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5038586761","display_name":"Deborah L. Warden","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I148314036","display_name":"Uniformed Services University of the Health Sciences","ror":"https://ror.org/04r3kq386","country_code":"US","type":"education","lineage":["https://openalex.org/I148314036"]},{"id":"https://openalex.org/I2800363604","display_name":"Walter Reed National Military Medical Center","ror":"https://ror.org/025cem651","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330347796","https://openalex.org/I2800250139","https://openalex.org/I2800363604","https://openalex.org/I2800386880"]},{"id":"https://openalex.org/I4210121815","display_name":"National Institute on Alcohol Abuse and Alcoholism","ror":"https://ror.org/02jzrsm59","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210121815"]},{"id":"https://openalex.org/I4405268472","display_name":"Defense and Veterans Brain Injury Center","ror":"https://ror.org/01345ed13","country_code":"US","type":"government","lineage":["https://openalex.org/I4405268472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Deborah L. Warden","raw_affiliation_strings":["Received December 12, 2003; revised June 17, 2004; accepted June 24, 2004. From the Laboratory of Neurogenetics, National Institute on Alcohol Abuse and Alcoholism, NIH, Rockville, Maryland; the Defense and Veterans Brain Injury Center, Departments of Neurology and Neurosurgery, Walter Reed Army Medical Center, Washington, DC; the Uniformed Services University of Health Sciences, Bethesda, Maryland. Address correspondence to Dr. Warden, Defense and Veterans Brain Injury Center, Walter Reed Army Medical"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Received December 12, 2003; revised June 17, 2004; accepted June 24, 2004. From the Laboratory of Neurogenetics, National Institute on Alcohol Abuse and Alcoholism, NIH, Rockville, Maryland; the Defense and Veterans Brain Injury Center, Departments of Neurology and Neurosurgery, Walter Reed Army Medical Center, Washington, DC; the Uniformed Services University of Health Sciences, Bethesda, Maryland. Address correspondence to Dr. Warden, Defense and Veterans Brain Injury Center, Walter Reed Army Medical","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I148314036","https://openalex.org/I2800363604","https://openalex.org/I4210121815","https://openalex.org/I4405268472"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.9287,"has_fulltext":true,"cited_by_count":115,"citation_normalized_percentile":{"value":0.84217516,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"17","issue":"4","first_page":"465","last_page":"471"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10056","display_name":"Neurotransmitter Receptor Influence on Behavior","score":0.5029000043869019,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10056","display_name":"Neurotransmitter Receptor Influence on Behavior","score":0.5029000043869019,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10416","display_name":"Traumatic Brain Injury Research","score":0.3206000030040741,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10042","display_name":"Neural and Behavioral Psychology Studies","score":0.04969999939203262,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/comt-val158met-polymorphism","display_name":"COMT Val158Met polymorphism","score":0.972000002861023},{"id":"https://openalex.org/keywords/traumatic-brain-injury","display_name":"traumatic brain injury","score":0.8809999823570251},{"id":"https://openalex.org/keywords/executive-function","display_name":"executive function","score":0.9269999861717224},{"id":"https://openalex.org/keywords/dopamine","display_name":"dopamine","score":0.6970000267028809},{"id":"https://openalex.org/keywords/catechol-o-methyltransferase","display_name":"catechol-O-methyltransferase","score":0.8410000205039978},{"id":"https://openalex.org/keywords/wisconsin-card-sorting-test","display_name":"Wisconsin Card Sorting Test","score":0.7860000133514404},{"id":"https://openalex.org/keywords/perseveration","display_name":"perseveration","score":0.9160000085830688},{"id":"https://openalex.org/keywords/gene-environment-interaction","display_name":"gene-environment interaction","score":0.6520000100135803},{"id":"https://openalex.org/keywords/frontal-lobe-function","display_name":"frontal lobe function","score":0.6079999804496765}],"concepts":[{"id":"https://openalex.org/C185361966","wikidata":"https://www.wikidata.org/wiki/Q94291140","display_name":"Catechol-O-methyl transferase","level":4,"score":0.7902464866638184},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.6639907360076904},{"id":"https://openalex.org/C2778420670","wikidata":"https://www.wikidata.org/wiki/Q549525","display_name":"Wisconsin Card Sorting Test","level":4,"score":0.6529451608657837},{"id":"https://openalex.org/C2779985164","wikidata":"https://www.wikidata.org/wiki/Q5419936","display_name":"Executive dysfunction","level":4,"score":0.6505526900291443},{"id":"https://openalex.org/C2775968953","wikidata":"https://www.wikidata.org/wiki/Q783092","display_name":"Executive functions","level":3,"score":0.5225622057914734},{"id":"https://openalex.org/C187869287","wikidata":"https://www.wikidata.org/wiki/Q2032061","display_name":"Endophenotype","level":3,"score":0.5190559029579163},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.46678459644317627},{"id":"https://openalex.org/C2781017439","wikidata":"https://www.wikidata.org/wiki/Q1995526","display_name":"Traumatic brain injury","level":2,"score":0.45951831340789795},{"id":"https://openalex.org/C149737253","wikidata":"https://www.wikidata.org/wiki/Q3240252","display_name":"Polymorphism (computer science)","level":4,"score":0.4467846155166626},{"id":"https://openalex.org/C180754005","wikidata":"https://www.wikidata.org/wiki/Q80726","display_name":"Allele","level":3,"score":0.4279329180717468},{"id":"https://openalex.org/C70410870","wikidata":"https://www.wikidata.org/wiki/Q199906","display_name":"Clinical psychology","level":1,"score":0.380337655544281},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3251182436943054},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.2844407260417938},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2805393934249878},{"id":"https://openalex.org/C169900460","wikidata":"https://www.wikidata.org/wiki/Q2200417","display_name":"Cognition","level":2,"score":0.2748865485191345},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.26363885402679443},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.1995287537574768},{"id":"https://openalex.org/C14216870","wikidata":"https://www.wikidata.org/wiki/Q3872","display_name":"Neuropsychology","level":3,"score":0.1885809600353241},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1360805630683899},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.13395452499389648}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000704","descriptor_name":"Analysis of Variance","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001930","descriptor_name":"Brain Injuries","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D002394","descriptor_name":"Catechol O-Methyltransferase","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008715","descriptor_name":"Methionine","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D009483","descriptor_name":"Neuropsychological Tests","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":false},{"descriptor_ui":"D011110","descriptor_name":"Polymorphism, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011340","descriptor_name":"Problem Solving","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D014633","descriptor_name":"Valine","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D020022","descriptor_name":"Genetic Predisposition to Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1176/appi.neuropsych.17.4.465","doi":"https://doi.org/10.1176/appi.neuropsych.17.4.465","is_oa":false,"landing_page_url":"https://doi.org/10.1176/appi.neuropsych.17.4.465","pdf_url":null,"source":{"id":"https://openalex.org/S50352613","display_name":"Journal of Neuropsychiatry","issn_l":"0895-0172","issn":["0895-0172","1545-7222"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4320800570","host_organization_name":"American Psychiatric Association Publishing","host_organization_lineage":["https://openalex.org/P4320800570","https://openalex.org/P4310316602"],"host_organization_lineage_names":["American Psychiatric Association Publishing","American Psychiatric Association"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Neuropsychiatry","raw_type":"journal-article"},{"id":"doi:10.1176/jnp.17.4.465","doi":"https://doi.org/10.1176/jnp.17.4.465","is_oa":true,"landing_page_url":"https://doi.org/10.1176/jnp.17.4.465","pdf_url":"https://neuro.psychiatryonline.org/doi/pdf/10.1176/jnp.17.4.465","source":{"id":"https://openalex.org/S50352613","display_name":"Journal of Neuropsychiatry","issn_l":"0895-0172","issn":["0895-0172","1545-7222"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4320800570","host_organization_name":"American Psychiatric Association Publishing","host_organization_lineage":["https://openalex.org/P4320800570","https://openalex.org/P4310316602"],"host_organization_lineage_names":["American Psychiatric Association Publishing","American Psychiatric Association"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Neuropsychiatry and Clinical Neurosciences","raw_type":"journal-article"},{"id":"pmid:16387984","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16387984","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of neuropsychiatry and clinical neurosciences","raw_type":"Comparative Study"}],"best_oa_location":{"id":"doi:10.1176/jnp.17.4.465","doi":"https://doi.org/10.1176/jnp.17.4.465","is_oa":true,"landing_page_url":"https://doi.org/10.1176/jnp.17.4.465","pdf_url":"https://neuro.psychiatryonline.org/doi/pdf/10.1176/jnp.17.4.465","source":{"id":"https://openalex.org/S50352613","display_name":"Journal of Neuropsychiatry","issn_l":"0895-0172","issn":["0895-0172","1545-7222"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4320800570","host_organization_name":"American Psychiatric Association Publishing","host_organization_lineage":["https://openalex.org/P4320800570","https://openalex.org/P4310316602"],"host_organization_lineage_names":["American Psychiatric Association Publishing","American Psychiatric Association"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Neuropsychiatry and Clinical Neurosciences","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"score":0.7400000095367432,"id":"https://metadata.un.org/sdg/1","display_name":"No poverty"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320306078","display_name":"U.S. Department of Defense","ror":"https://ror.org/0447fe631"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2104090580.pdf","grobid_xml":"https://content.openalex.org/works/W2104090580.grobid-xml"},"referenced_works_count":24,"referenced_works":["https://openalex.org/W1970899333","https://openalex.org/W1983043718","https://openalex.org/W1991954214","https://openalex.org/W2000327906","https://openalex.org/W2031020345","https://openalex.org/W2032866243","https://openalex.org/W2039148287","https://openalex.org/W2044546476","https://openalex.org/W2049702924","https://openalex.org/W2057646888","https://openalex.org/W2075370186","https://openalex.org/W2093327286","https://openalex.org/W2100040984","https://openalex.org/W2114083018","https://openalex.org/W2124793618","https://openalex.org/W2125483448","https://openalex.org/W2129249260","https://openalex.org/W2130812265","https://openalex.org/W2132569582","https://openalex.org/W2606481147","https://openalex.org/W2799988518","https://openalex.org/W2808339913","https://openalex.org/W2810887452","https://openalex.org/W4323874097"],"related_works":["https://openalex.org/W2316599636","https://openalex.org/W1969069107","https://openalex.org/W2977054314","https://openalex.org/W2142733669","https://openalex.org/W1982765225","https://openalex.org/W7011740057","https://openalex.org/W876229980","https://openalex.org/W1984900904","https://openalex.org/W2206787354","https://openalex.org/W2514057661"],"abstract_inverted_index":{"Catechol-O-methyltransferase":[0],"(COMT)":[1],"is":[2],"thought":[3],"to":[4,32,92,184,195,207],"functionally":[5],"modulate":[6],"dopamine":[7,47],"neurons,":[8],"thus":[9],"likely":[10],"influencing":[11],"frontal-executive":[12],"functioning.":[13,53],"High":[14],"enzyme":[15,21,68,84],"activity":[16,22,69,85,145,162],"(COMT":[17,23],"Val)":[18],"and":[19,65,95,105,203],"low":[20,67],"Met)":[24],"are":[25],"functional":[26],"polymorphisms":[27],"resulting":[28],"from":[29],"a":[30,101],"G":[31],"A":[33],"transition":[34],"in":[35,50,199],"exon":[36],"4":[37],"(codon":[38],"158)":[39],"of":[40,76,113,124,126,133,168,181,193],"the":[41,55,66,82,93,109,117,143,152,160,165,179,190],"human":[42],"COMT":[43,110,118,182],"gene.":[44],"Decreased":[45],"cortical":[46],"should":[48],"result":[49],"poorer":[51],"executive":[52,77,127,185,196],"Therefore,":[54],"authors":[56],"hypothesized":[57],"that":[58],"individuals":[59,80,90,204,208],"with":[60,81,136,205,209],"traumatic":[61],"brain":[62],"injury":[63],"(TBI)":[64],"polymorphism":[70],"would":[71],"perform":[72],"better":[73],"on":[74,151],"tests":[75],"functioning":[78,128],"than":[79],"high":[83],"polymorphism.":[86,111],"One":[87],"hundred":[88],"thirteen":[89],"referred":[91],"Defense":[94],"Veterans":[96],"Brain":[97],"Injury":[98],"Center":[99],"underwent":[100],"comprehensive":[102],"TBI":[103,177],"evaluation":[104],"were":[106],"genotyped":[107],"for":[108,121,138,142,159],"Comparison":[112],"mean":[114],"differences":[115],"among":[116],"genotype":[119,194],"groups":[120],"several":[122],"measures":[123],"aspects":[125],"was":[129],"conducted":[130],"using":[131],"analysis":[132],"variance":[134],"(ANOVA)":[135],"adjustment":[137],"multiple":[139],"comparisons.":[140],"Homozygotes":[141],"higher":[144],"allele":[146,163],"made":[147],"more":[148],"perseverative":[149,169],"responses":[150],"Wisconsin":[153],"Card":[154],"Sorting":[155],"Test,":[156],"while":[157],"homozygotes":[158],"lower":[161],"had":[164],"least":[166],"number":[167],"responses.":[170],"While":[171],"it":[172],"cannot":[173],"be":[174],"determined":[175],"whether":[176],"influenced":[178],"association":[180],"Val158Met":[183],"functioning,":[186],"these":[187],"data":[188],"extend":[189],"known":[191],"relationship":[192],"performance":[197],"seen":[198],"healthy":[200],"comparison":[201],"subjects":[202],"schizophrenia":[206],"TBI.":[210]},"counts_by_year":[{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":5},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":7},{"year":2018,"cited_by_count":6},{"year":2017,"cited_by_count":10},{"year":2016,"cited_by_count":4},{"year":2015,"cited_by_count":11},{"year":2014,"cited_by_count":6},{"year":2013,"cited_by_count":5},{"year":2012,"cited_by_count":7}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}
