{"id":"https://openalex.org/W2104028323","doi":"https://doi.org/10.1016/j.neurobiolaging.2014.07.040","title":"Genetic background influences age-related decline in visual and nonvisual retinal responses, circadian rhythms, and sleep","display_name":"Genetic background influences age-related decline in visual and nonvisual retinal responses, circadian rhythms, and sleep","publication_year":2014,"publication_date":"2014-08-02","ids":{"openalex":"https://openalex.org/W2104028323","doi":"https://doi.org/10.1016/j.neurobiolaging.2014.07.040","mag":"2104028323","pmid":"https://pubmed.ncbi.nlm.nih.gov/25179226","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4270439"},"language":"en","primary_location":{"id":"doi:10.1016/j.neurobiolaging.2014.07.040","doi":"https://doi.org/10.1016/j.neurobiolaging.2014.07.040","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.neurobiolaging.2014.07.040","pdf_url":"https://www.sciencedirect.com/science/article/pii/S0197458014005090/pdf","source":{"id":"https://openalex.org/S284573","display_name":"Neurobiology of Aging","issn_l":"0197-4580","issn":["0197-4580","1558-1497"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neurobiology of Aging","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://www.sciencedirect.com/science/article/pii/S0197458014005090/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5040039796","display_name":"Gareth T. Banks","orcid":"https://orcid.org/0000-0002-8647-667X","observed_orcids":["https://orcid.org/0000-0002-8647-667X"]},"institutions":[{"id":"https://openalex.org/I4210086857","display_name":"Mary Lyon Centre at MRC Harwell","ror":"https://ror.org/0001h1y25","country_code":"GB","type":"facility","lineage":["https://openalex.org/I4210086857","https://openalex.org/I4210087105","https://openalex.org/I90344618"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Gareth Banks","raw_affiliation_strings":["MRC Harwell, Harwell Science and Innovation Campus, Oxfordshire, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"MRC Harwell, Harwell Science and Innovation Campus, Oxfordshire, UK","institution_ids":["https://openalex.org/I4210086857"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028445398","display_name":"Ines Heise","orcid":"https://orcid.org/0000-0001-6290-2788","observed_orcids":["https://orcid.org/0000-0001-6290-2788"]},"institutions":[{"id":"https://openalex.org/I4210086857","display_name":"Mary Lyon Centre at MRC Harwell","ror":"https://ror.org/0001h1y25","country_code":"GB","type":"facility","lineage":["https://openalex.org/I4210086857","https://openalex.org/I4210087105","https://openalex.org/I90344618"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Ines Heise","raw_affiliation_strings":["MRC Harwell, Harwell Science and Innovation Campus, Oxfordshire, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"MRC Harwell, Harwell Science and Innovation Campus, Oxfordshire, UK","institution_ids":["https://openalex.org/I4210086857"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083747159","display_name":"Becky Starbuck","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210086857","display_name":"Mary Lyon Centre at MRC Harwell","ror":"https://ror.org/0001h1y25","country_code":"GB","type":"facility","lineage":["https://openalex.org/I4210086857","https://openalex.org/I4210087105","https://openalex.org/I90344618"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Becky Starbuck","raw_affiliation_strings":["MRC Harwell, Harwell Science and Innovation Campus, Oxfordshire, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"MRC Harwell, Harwell Science and Innovation Campus, Oxfordshire, UK","institution_ids":["https://openalex.org/I4210086857"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054255497","display_name":"Tamzin Osborne","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210086857","display_name":"Mary Lyon Centre at MRC Harwell","ror":"https://ror.org/0001h1y25","country_code":"GB","type":"facility","lineage":["https://openalex.org/I4210086857","https://openalex.org/I4210087105","https://openalex.org/I90344618"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Tamzin Osborne","raw_affiliation_strings":["MRC Harwell, Harwell Science and Innovation Campus, Oxfordshire, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"MRC Harwell, Harwell Science and Innovation Campus, Oxfordshire, UK","institution_ids":["https://openalex.org/I4210086857"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028483845","display_name":"Laura Wisby","orcid":"https://orcid.org/0000-0001-8593-7174","observed_orcids":["https://orcid.org/0000-0001-8593-7174"]},"institutions":[{"id":"https://openalex.org/I4210086857","display_name":"Mary Lyon Centre at MRC Harwell","ror":"https://ror.org/0001h1y25","country_code":"GB","type":"facility","lineage":["https://openalex.org/I4210086857","https://openalex.org/I4210087105","https://openalex.org/I90344618"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Laura Wisby","raw_affiliation_strings":["MRC Harwell, Harwell Science and Innovation Campus, Oxfordshire, UK"],"raw_orcid":"https://orcid.org/0000-0001-8593-7174","affiliations":[{"raw_affiliation_string":"MRC Harwell, Harwell Science and Innovation Campus, Oxfordshire, UK","institution_ids":["https://openalex.org/I4210086857"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021278395","display_name":"Paul K Potter","orcid":"https://orcid.org/0000-0003-2689-2361","observed_orcids":["https://orcid.org/0000-0003-2689-2361"]},"institutions":[{"id":"https://openalex.org/I4210086857","display_name":"Mary Lyon Centre at MRC Harwell","ror":"https://ror.org/0001h1y25","country_code":"GB","type":"facility","lineage":["https://openalex.org/I4210086857","https://openalex.org/I4210087105","https://openalex.org/I90344618"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Paul Potter","raw_affiliation_strings":["MRC Harwell, Harwell Science and Innovation Campus, Oxfordshire, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"MRC Harwell, Harwell Science and Innovation Campus, Oxfordshire, UK","institution_ids":["https://openalex.org/I4210086857"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070906741","display_name":"Ian J. Jackson","orcid":"https://orcid.org/0000-0001-6526-0688","observed_orcids":["https://orcid.org/0000-0001-6526-0688"]},"institutions":[{"id":"https://openalex.org/I2800150677","display_name":"Western General Hospital","ror":"https://ror.org/009kr6r15","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1324252669","https://openalex.org/I2800150677"]},{"id":"https://openalex.org/I4210158898","display_name":"Institute of Genetics and Cancer","ror":"https://ror.org/05hygey35","country_code":"GB","type":"facility","lineage":["https://openalex.org/I4210087105","https://openalex.org/I4210158898","https://openalex.org/I90344618","https://openalex.org/I98677209"]},{"id":"https://openalex.org/I4387154614","display_name":"MRC Human Genetics Unit","ror":"https://ror.org/011jsc803","country_code":"GB","type":"facility","lineage":["https://openalex.org/I4210087105","https://openalex.org/I4387154614","https://openalex.org/I90344618","https://openalex.org/I98677209"]},{"id":"https://openalex.org/I98677209","display_name":"University of Edinburgh","ror":"https://ror.org/01nrxwf90","country_code":"GB","type":"education","lineage":["https://openalex.org/I98677209"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Ian J. Jackson","raw_affiliation_strings":["MRC Human Genetics Unit, MRC IGMM, University of Edinburgh, Western General Hospital, Edinburgh, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"MRC Human Genetics Unit, MRC IGMM, University of Edinburgh, Western General Hospital, Edinburgh, UK","institution_ids":["https://openalex.org/I2800150677","https://openalex.org/I4210158898","https://openalex.org/I4387154614","https://openalex.org/I98677209"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019911441","display_name":"F. Foster","orcid":"https://orcid.org/0000-0001-6055-2067","observed_orcids":["https://orcid.org/0000-0001-6055-2067"]},"institutions":[{"id":"https://openalex.org/I2802742124","display_name":"John Radcliffe Hospital","ror":"https://ror.org/0080acb59","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2802742124","https://openalex.org/I4210127145","https://openalex.org/I4210147381"]},{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Russell G. Foster","raw_affiliation_strings":["Nuffield Laboratory of Ophthalmology, Nuffield Department of Clinical Neurosciences, University of Oxford, John Radcliffe Hospital, Oxford, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Nuffield Laboratory of Ophthalmology, Nuffield Department of Clinical Neurosciences, University of Oxford, John Radcliffe Hospital, Oxford, UK","institution_ids":["https://openalex.org/I2802742124","https://openalex.org/I40120149"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067384437","display_name":"Stuart N. Peirson","orcid":"https://orcid.org/0000-0003-3653-834X","observed_orcids":["https://orcid.org/0000-0003-3653-834X"]},"institutions":[{"id":"https://openalex.org/I2802742124","display_name":"John Radcliffe Hospital","ror":"https://ror.org/0080acb59","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2802742124","https://openalex.org/I4210127145","https://openalex.org/I4210147381"]},{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Stuart N. Peirson","raw_affiliation_strings":["Nuffield Laboratory of Ophthalmology, Nuffield Department of Clinical Neurosciences, University of Oxford, John Radcliffe Hospital, Oxford, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Nuffield Laboratory of Ophthalmology, Nuffield Department of Clinical Neurosciences, University of Oxford, John Radcliffe Hospital, Oxford, UK","institution_ids":["https://openalex.org/I2802742124","https://openalex.org/I40120149"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5011576532","display_name":"Patrick M. Nolan","orcid":"https://orcid.org/0000-0001-5550-0334","observed_orcids":["https://orcid.org/0000-0001-5550-0334","https://orcid.org/0000-0002-9304-6715"]},"institutions":[{"id":"https://openalex.org/I4210086857","display_name":"Mary Lyon Centre at MRC Harwell","ror":"https://ror.org/0001h1y25","country_code":"GB","type":"facility","lineage":["https://openalex.org/I4210086857","https://openalex.org/I4210087105","https://openalex.org/I90344618"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Patrick M. Nolan","raw_affiliation_strings":["MRC Harwell, Harwell Science and Innovation Campus, Oxfordshire, UK. Electronic address: p.nolan@har.mrc.ac.uk","MRC Harwell, Harwell Science and Innovation Campus, Oxfordshire, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"MRC Harwell, Harwell Science and Innovation Campus, Oxfordshire, UK. Electronic address: p.nolan@har.mrc.ac.uk","institution_ids":["https://openalex.org/I4210086857"]},{"raw_affiliation_string":"MRC Harwell, Harwell Science and Innovation Campus, Oxfordshire, UK","institution_ids":["https://openalex.org/I4210086857"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5011576532"],"corresponding_institution_ids":["https://openalex.org/I4210086857"],"apc_list":{"value":3430,"currency":"USD","value_usd":3430},"apc_paid":{"value":3430,"currency":"USD","value_usd":3430},"fwci":2.4371,"has_fulltext":true,"cited_by_count":66,"citation_normalized_percentile":{"value":0.87746479,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":99},"biblio":{"volume":"36","issue":"1","first_page":"380","last_page":"393"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10342","display_name":"Circadian rhythm and melatonin","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10342","display_name":"Circadian rhythm and melatonin","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10985","display_name":"Sleep and Wakefulness Research","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10676","display_name":"Genetics, Aging, and Longevity in Model Organisms","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/1302","display_name":"Aging"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/aging","display_name":"aging","score":0.8569999933242798},{"id":"https://openalex.org/keywords/circadian-rhythm","display_name":"circadian rhythm","score":0.8230000138282776},{"id":"https://openalex.org/keywords/sleep","display_name":"sleep","score":0.6660000085830688},{"id":"https://openalex.org/keywords/retinal-photoreceptors","display_name":"retinal photoreceptors","score":0.6850000023841858},{"id":"https://openalex.org/keywords/genetic-background","display_name":"genetic background","score":0.6480000019073486},{"id":"https://openalex.org/keywords/mouse-strains","display_name":"mouse strains","score":0.7799999713897705},{"id":"https://openalex.org/keywords/c57bl-6j-mice","display_name":"C57BL/6J mice","score":0.9580000042915344},{"id":"https://openalex.org/keywords/c57bl-6n","display_name":"C57BL/6N","score":0.9739999771118164},{"id":"https://openalex.org/keywords/pupillary-light-reflex","display_name":"pupillary light reflex","score":0.8159999847412109},{"id":"https://openalex.org/keywords/cataract-formation","display_name":"cataract formation","score":0.9110000133514404},{"id":"https://openalex.org/keywords/sleep-fragmentation","display_name":"sleep fragmentation","score":0.9639999866485596},{"id":"https://openalex.org/keywords/light-input","display_name":"light input","score":0.4729999899864197}],"concepts":[{"id":"https://openalex.org/C121446783","wikidata":"https://www.wikidata.org/wiki/Q208353","display_name":"Circadian rhythm","level":2,"score":0.8470057249069214},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7013294696807861},{"id":"https://openalex.org/C127716648","wikidata":"https://www.wikidata.org/wiki/Q104053","display_name":"Phenotype","level":3,"score":0.5440333485603333},{"id":"https://openalex.org/C3020527817","wikidata":"https://www.wikidata.org/wiki/Q20811883","display_name":"Mouse strain","level":3,"score":0.47833868861198425},{"id":"https://openalex.org/C2775841894","wikidata":"https://www.wikidata.org/wiki/Q4683692","display_name":"Sleep (system call)","level":2,"score":0.46930745244026184},{"id":"https://openalex.org/C500499127","wikidata":"https://www.wikidata.org/wiki/Q332154","display_name":"Ageing","level":2,"score":0.41773489117622375},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.41715461015701294},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.4132440686225891},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.193450927734375},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000375","descriptor_name":"Aging","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002940","descriptor_name":"Circadian Rhythm","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D002940","descriptor_name":"Circadian Rhythm","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D008809","descriptor_name":"Mice, Inbred C3H","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008810","descriptor_name":"Mice, Inbred C57BL","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008815","descriptor_name":"Mice, Inbred Strains","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012890","descriptor_name":"Sleep","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D012890","descriptor_name":"Sleep","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D014792","descriptor_name":"Visual Acuity","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D014792","descriptor_name":"Visual Acuity","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D020419","descriptor_name":"Photoreceptor Cells, Vertebrate","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1016/j.neurobiolaging.2014.07.040","doi":"https://doi.org/10.1016/j.neurobiolaging.2014.07.040","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.neurobiolaging.2014.07.040","pdf_url":"https://www.sciencedirect.com/science/article/pii/S0197458014005090/pdf","source":{"id":"https://openalex.org/S284573","display_name":"Neurobiology of Aging","issn_l":"0197-4580","issn":["0197-4580","1558-1497"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neurobiology of Aging","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:4270439","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4270439","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neurobiol Aging","raw_type":"Text"},{"id":"pmid:25179226","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25179226","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neurobiology of aging","raw_type":"Journal Article"},{"id":"pmh:oai:pure.ed.ac.uk:publications/17dfb9da-03f8-4a19-acb3-6b578a1c0397","doi":null,"is_oa":true,"landing_page_url":"https://www.research.ed.ac.uk/en/publications/17dfb9da-03f8-4a19-acb3-6b578a1c0397","pdf_url":"https://www.research.ed.ac.uk/files/16964648/Genetic_background_influences_age_related_decline_in_visual_and_nonvisual_retinal_responses_circadian_rhythms_and_sleep.pdf","source":{"id":"https://openalex.org/S4306400321","display_name":"Edinburgh Research Explorer (University of Edinburgh)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I98677209","host_organization_name":"University of Edinburgh","host_organization_lineage":["https://openalex.org/I98677209"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Banks, G, Heise, I, Starbuck, B, Osborne, T, Wisby, L, Potter, P, Jackson, I J, Foster, R G, Peirson, S N & Nolan, P M 2014, 'Genetic background influences age-related decline in visual and nonvisual retinal responses, circadian rhythms, and sleep', Neurobiology of Aging. https://doi.org/10.1016/j.neurobiolaging.2014.07.040","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1016/j.neurobiolaging.2014.07.040","doi":"https://doi.org/10.1016/j.neurobiolaging.2014.07.040","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.neurobiolaging.2014.07.040","pdf_url":"https://www.sciencedirect.com/science/article/pii/S0197458014005090/pdf","source":{"id":"https://openalex.org/S284573","display_name":"Neurobiology of Aging","issn_l":"0197-4580","issn":["0197-4580","1558-1497"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neurobiology of Aging","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.4043000042438507,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G1012387763","display_name":"Sleep and Circadian Neuroscience Institute (SCNi)","funder_award_id":"098461","funder_id":"https://openalex.org/F4320311904","funder_display_name":"Wellcome Trust"},{"id":"https://openalex.org/G287413396","display_name":"Regulation of Sleep by Environmental Light","funder_award_id":"BB/I021086/1","funder_id":"https://openalex.org/F4320334629","funder_display_name":"Biotechnology and Biological Sciences Research Council"},{"id":"https://openalex.org/G2986243141","display_name":null,"funder_award_id":"BB/I021086/1","funder_id":"https://openalex.org/F4320334629","funder_display_name":"Biotechnology and Biological Sciences Research Council"},{"id":"https://openalex.org/G5993129374","display_name":null,"funder_award_id":"098461/Z/12/Z","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"},{"id":"https://openalex.org/G654448798","display_name":"Sleep and Circadian Neuroscience Institute (SCNi)","funder_award_id":"098461/Z/12/Z","funder_id":"https://openalex.org/F4320311904","funder_display_name":"Wellcome Trust"},{"id":"https://openalex.org/G892560942","display_name":null,"funder_award_id":"098461/Z/12/Z","funder_id":"https://openalex.org/F4320334629","funder_display_name":"Biotechnology and Biological Sciences Research Council"},{"id":"https://openalex.org/G9000128195","display_name":null,"funder_award_id":"098461/Z/12","funder_id":"https://openalex.org/F4320311904","funder_display_name":"Wellcome Trust"},{"id":"https://openalex.org/G9000269534","display_name":null,"funder_award_id":"098461/Z","funder_id":"https://openalex.org/F4320311904","funder_display_name":"Wellcome Trust"}],"funders":[{"id":"https://openalex.org/F4320311904","display_name":"Wellcome Trust","ror":"https://ror.org/029chgv08"},{"id":"https://openalex.org/F4320332167","display_name":"Directorate for Biological Sciences","ror":"https://ror.org/001xhss06"},{"id":"https://openalex.org/F4320334626","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517"},{"id":"https://openalex.org/F4320334629","display_name":"Biotechnology and Biological Sciences Research Council","ror":"https://ror.org/00cwqg982"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2104028323.pdf","grobid_xml":"https://content.openalex.org/works/W2104028323.grobid-xml"},"referenced_works_count":60,"referenced_works":["https://openalex.org/W172046951","https://openalex.org/W1518938059","https://openalex.org/W1526987274","https://openalex.org/W1601733265","https://openalex.org/W1605371170","https://openalex.org/W1918892711","https://openalex.org/W1969535988","https://openalex.org/W1969904423","https://openalex.org/W1970075441","https://openalex.org/W1970600663","https://openalex.org/W1972636740","https://openalex.org/W1973056324","https://openalex.org/W1975772363","https://openalex.org/W1978847290","https://openalex.org/W1980202250","https://openalex.org/W1990264305","https://openalex.org/W1991090223","https://openalex.org/W1997660876","https://openalex.org/W2001037630","https://openalex.org/W2001065634","https://openalex.org/W2001644882","https://openalex.org/W2013713160","https://openalex.org/W2013935903","https://openalex.org/W2014007498","https://openalex.org/W2014448534","https://openalex.org/W2018925811","https://openalex.org/W2024314908","https://openalex.org/W2027203208","https://openalex.org/W2038361969","https://openalex.org/W2041102000","https://openalex.org/W2043888099","https://openalex.org/W2048016988","https://openalex.org/W2056478360","https://openalex.org/W2063366885","https://openalex.org/W2068980363","https://openalex.org/W2070154168","https://openalex.org/W2072018453","https://openalex.org/W2081402812","https://openalex.org/W2087744632","https://openalex.org/W2092319652","https://openalex.org/W2096301549","https://openalex.org/W2100123460","https://openalex.org/W2101313186","https://openalex.org/W2104301336","https://openalex.org/W2105051672","https://openalex.org/W2109276098","https://openalex.org/W2112204723","https://openalex.org/W2115576097","https://openalex.org/W2123631888","https://openalex.org/W2125735850","https://openalex.org/W2135393774","https://openalex.org/W2141331474","https://openalex.org/W2147496694","https://openalex.org/W2147819824","https://openalex.org/W2148840336","https://openalex.org/W2155377690","https://openalex.org/W2157592619","https://openalex.org/W2160261786","https://openalex.org/W4300834245","https://openalex.org/W6639972015"],"related_works":["https://openalex.org/W2148840336","https://openalex.org/W4406627870","https://openalex.org/W2032406627","https://openalex.org/W3106778440","https://openalex.org/W1918892711","https://openalex.org/W2023225788","https://openalex.org/W1973452195","https://openalex.org/W2920728968","https://openalex.org/W1994719199","https://openalex.org/W2048854694"],"abstract_inverted_index":{"The":[0,74],"circadian":[1,172],"system":[2],"is":[3,81],"entrained":[4],"to":[5,49,61,119,136,141,154],"the":[6,41,55,63,88,109,149,165,215,229,236,246],"environmental":[7],"light/dark":[8],"cycle":[9],"via":[10],"retinal":[11],"photoreceptors":[12],"and":[13,19,130,174,177,190,207,240,245],"regulates":[14],"numerous":[15],"aspects":[16],"of":[17,54,98,126,167,224,231,248],"physiology":[18],"behavior,":[20,171],"including":[21,123,228],"sleep.":[22],"These":[23],"processes":[24,68],"are":[25,47,69,181,211],"all":[26,212],"key":[27],"factors":[28,65],"in":[29,128,235,242],"healthy":[30],"aging":[31,150,168,216,226],"showing":[32],"a":[33,103,222],"gradual":[34],"decline":[35,46,234],"with":[36],"age.":[37],"Despite":[38],"their":[39,198],"importance,":[40],"exact":[42],"mechanisms":[43],"underlying":[44,66],"this":[45],"yet":[48],"be":[50,120,137],"fully":[51],"understood.":[52],"One":[53],"most":[56,75],"effective":[57],"tools":[58],"we":[59,116,184,219],"have":[60,93,185,220],"understand":[62,155],"genetic":[64,105,111,157],"these":[67,129,179],"genetically":[70],"inbred":[71],"mouse":[72,79,99,114,145,182,192],"strains.":[73,132],"commonly":[76],"used":[77],"reference":[78],"strain":[80],"C57BL/6J,":[82,187],"but":[83,152],"recently,":[84],"resources":[85],"such":[86],"as":[87],"International":[89],"Knockout":[90],"Mouse":[91],"Consortium":[92],"started":[94],"producing":[95],"large":[96],"numbers":[97],"mutant":[100],"lines":[101],"on":[102,169],"pure":[104],"background,":[106],"C57BL/6N.":[107],"Considering":[108],"substantial":[110],"diversity":[112],"between":[113],"strains":[115,146,193],"expect":[117],"there":[118],"phenotypic":[121],"differences,":[122],"differential":[124],"effects":[125,166,180],"aging,":[127],"other":[131],"Such":[133],"differences":[134],"need":[135],"characterized":[138],"not":[139],"only":[140],"establish":[142],"how":[143,156],"different":[144],"may":[147],"model":[148],"process":[151],"also":[153],"background":[158],"might":[159],"modify":[160],"age-related":[161],"phenotypes.":[162],"To":[163],"ascertain":[164],"sleep/wake":[170],"rhythms,":[173],"light":[175,208,238],"input":[176,209],"whether":[178],"strain-dependent,":[183],"screened":[186],"C57BL/6N,":[188],"C3H-HeH,":[189],"C3H-Pde6b+":[191],"at":[194],"5":[195],"ages":[196],"throughout":[197],"life":[199],"span.":[200],"Our":[201],"data":[202],"show":[203],"that":[204],"sleep,":[205],"circadian,":[206],"parameters":[210],"disrupted":[213],"by":[214],"process.":[217],"Moreover,":[218],"cataloged":[221],"number":[223],"strain-specific":[225],"effects,":[227],"rate":[230],"cataract":[232],"development,":[233],"pupillary":[237],"response,":[239],"changes":[241],"sleep":[243],"fragmentation":[244],"proportion":[247],"time":[249],"spent":[250],"asleep.":[251]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":11},{"year":2020,"cited_by_count":9},{"year":2019,"cited_by_count":7},{"year":2018,"cited_by_count":8},{"year":2017,"cited_by_count":6},{"year":2016,"cited_by_count":4},{"year":2015,"cited_by_count":5}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}
