{"id":"https://openalex.org/W2103784428","doi":"https://doi.org/10.1017/s1461145714000674","title":"The effects of methylphenidate on resting-state striatal, thalamic and global functional connectivity in healthy adults","display_name":"The effects of methylphenidate on resting-state striatal, thalamic and global functional connectivity in healthy adults","publication_year":2014,"publication_date":"2014-05-13","ids":{"openalex":"https://openalex.org/W2103784428","doi":"https://doi.org/10.1017/s1461145714000674","mag":"2103784428","pmid":"https://pubmed.ncbi.nlm.nih.gov/24825078","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4506752"},"language":"en","primary_location":{"id":"doi:10.1017/s1461145714000674","doi":"https://doi.org/10.1017/s1461145714000674","is_oa":true,"landing_page_url":"https://doi.org/10.1017/s1461145714000674","pdf_url":"https://academic.oup.com/ijnp/article-pdf/17/8/1177/17487140/17-8-1177.pdf","source":{"id":"https://openalex.org/S199972112","display_name":"The International Journal of Neuropsychopharmacology","issn_l":"1461-1457","issn":["1461-1457","1469-5111"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311647","host_organization_name":"University of Oxford","host_organization_lineage":["https://openalex.org/P4310311647"],"host_organization_lineage_names":["University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The International Journal of Neuropsychopharmacology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://academic.oup.com/ijnp/article-pdf/17/8/1177/17487140/17-8-1177.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5051390220","display_name":"Olivia M. Farr","orcid":"https://orcid.org/0000-0002-5182-3432","observed_orcids":["https://orcid.org/0000-0002-5182-3432"]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Olivia M. Farr","raw_affiliation_strings":["Interdepartmental Neuroscience Program, Yale University School of Medicine, New Haven, CT, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Interdepartmental Neuroscience Program, Yale University School of Medicine, New Haven, CT, USA","institution_ids":["https://openalex.org/I32971472"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100393987","display_name":"Sheng Zhang","orcid":"https://orcid.org/0000-0001-5786-6516","observed_orcids":["https://orcid.org/0000-0001-5786-6516"]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sheng Zhang","raw_affiliation_strings":["Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA","institution_ids":["https://openalex.org/I32971472"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087805638","display_name":"Sien Hu","orcid":"https://orcid.org/0000-0002-0718-4389","observed_orcids":["https://orcid.org/0000-0002-0718-4389"]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sien Hu","raw_affiliation_strings":["Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA","institution_ids":["https://openalex.org/I32971472"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084609706","display_name":"David Matuskey","orcid":"https://orcid.org/0000-0001-7508-6572","observed_orcids":["https://orcid.org/0000-0001-7508-6572"]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David Matuskey","raw_affiliation_strings":["Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA","institution_ids":["https://openalex.org/I32971472"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039356384","display_name":"Osama Abdelghany","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1323778983","display_name":"Yale New Haven Hospital","ror":"https://ror.org/05tszed37","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1323778983","https://openalex.org/I4210117499"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Osama Abdelghany","raw_affiliation_strings":["Investigational Drug Service, Yale New Haven Hospital, New Haven, CT, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Investigational Drug Service, Yale New Haven Hospital, New Haven, CT, USA","institution_ids":["https://openalex.org/I1323778983"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029861832","display_name":"Robert T. Malison","orcid":"https://orcid.org/0000-0001-8970-8483","observed_orcids":["https://orcid.org/0000-0001-8970-8483"]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert T. Malison","raw_affiliation_strings":["Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA","institution_ids":["https://openalex.org/I32971472"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5054640156","display_name":"Chiang\u2010Shan R. Li","orcid":"https://orcid.org/0000-0002-9393-1212","observed_orcids":["https://orcid.org/0000-0002-9393-1212"]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Chiang-shan R. Li","raw_affiliation_strings":["Interdepartmental Neuroscience Program, Yale University School of Medicine, New Haven, CT, USA","Department of Neurobiology, Yale University School of Medicine, New Haven, CT, USA","Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Interdepartmental Neuroscience Program, Yale University School of Medicine, New Haven, CT, USA","institution_ids":["https://openalex.org/I32971472"]},{"raw_affiliation_string":"Department of Neurobiology, Yale University School of Medicine, New Haven, CT, USA","institution_ids":["https://openalex.org/I32971472"]},{"raw_affiliation_string":"Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA","institution_ids":["https://openalex.org/I32971472"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":2042,"currency":"GBP","value_usd":2693},"apc_paid":null,"fwci":3.2172,"has_fulltext":true,"cited_by_count":59,"citation_normalized_percentile":{"value":0.91968085,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"17","issue":"08","first_page":"1177","last_page":"1191"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10241","display_name":"Functional Brain Connectivity Studies","score":0.9692000150680542,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10241","display_name":"Functional Brain Connectivity Studies","score":0.9692000150680542,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10056","display_name":"Neurotransmitter Receptor Influence on Behavior","score":0.021299999207258224,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10537","display_name":"Attention Deficit Hyperactivity Disorder","score":0.006500000134110451,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/methylphenidate","display_name":"methylphenidate","score":1.0},{"id":"https://openalex.org/keywords/resting-state-functional-connectivity","display_name":"resting-state functional connectivity","score":0.9959999918937683},{"id":"https://openalex.org/keywords/dorsal-striatum","display_name":"dorsal striatum","score":0.9739999771118164},{"id":"https://openalex.org/keywords/thalamus","display_name":"thalamus","score":1.0},{"id":"https://openalex.org/keywords/seed-based-functional-connectivity","display_name":"seed-based functional connectivity","score":0.7580000162124634},{"id":"https://openalex.org/keywords/primary-motor-cortex","display_name":"primary motor cortex","score":0.7990000247955322},{"id":"https://openalex.org/keywords/amygdala","display_name":"amygdala","score":0.8130000233650208},{"id":"https://openalex.org/keywords/hippocampus","display_name":"hippocampus","score":0.9980000257492065},{"id":"https://openalex.org/keywords/prefrontal-cortex","display_name":"prefrontal cortex","score":0.9599999785423279},{"id":"https://openalex.org/keywords/dopamine-transporter","display_name":"dopamine transporter","score":0.7110000252723694},{"id":"https://openalex.org/keywords/norepinephrine-transporter","display_name":"norepinephrine transporter","score":0.9449999928474426},{"id":"https://openalex.org/keywords/healthy-adults","display_name":"healthy adults","score":0.7459999918937683}],"concepts":[{"id":"https://openalex.org/C2777112843","wikidata":"https://www.wikidata.org/wiki/Q422112","display_name":"Methylphenidate","level":3,"score":0.8644145727157593},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.7326828241348267},{"id":"https://openalex.org/C66324658","wikidata":"https://www.wikidata.org/wiki/Q7316120","display_name":"Resting state fMRI","level":2,"score":0.6894344687461853},{"id":"https://openalex.org/C2779246727","wikidata":"https://www.wikidata.org/wiki/Q184215","display_name":"Thalamus","level":2,"score":0.6197929382324219},{"id":"https://openalex.org/C137183658","wikidata":"https://www.wikidata.org/wiki/Q461076","display_name":"Dopaminergic","level":3,"score":0.5692489743232727},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.5502533912658691},{"id":"https://openalex.org/C513476851","wikidata":"https://www.wikidata.org/wiki/Q170304","display_name":"Dopamine","level":2,"score":0.5159664750099182},{"id":"https://openalex.org/C2780062018","wikidata":"https://www.wikidata.org/wiki/Q1319792","display_name":"Striatum","level":3,"score":0.49630409479141235},{"id":"https://openalex.org/C2776743251","wikidata":"https://www.wikidata.org/wiki/Q1319792","display_name":"Ventral striatum","level":4,"score":0.4864042103290558},{"id":"https://openalex.org/C2779144063","wikidata":"https://www.wikidata.org/wiki/Q338924","display_name":"Amygdala","level":2,"score":0.47677353024482727},{"id":"https://openalex.org/C2776824294","wikidata":"https://www.wikidata.org/wiki/Q18344428","display_name":"Catecholaminergic","level":3,"score":0.4720878303050995},{"id":"https://openalex.org/C45715564","wikidata":"https://www.wikidata.org/wiki/Q1292103","display_name":"Connectome","level":3,"score":0.42157647013664246},{"id":"https://openalex.org/C2781195155","wikidata":"https://www.wikidata.org/wiki/Q18680","display_name":"Prefrontal cortex","level":3,"score":0.4162834882736206},{"id":"https://openalex.org/C3018011982","wikidata":"https://www.wikidata.org/wiki/Q7316120","display_name":"Functional connectivity","level":2,"score":0.33115166425704956},{"id":"https://openalex.org/C169900460","wikidata":"https://www.wikidata.org/wiki/Q2200417","display_name":"Cognition","level":2,"score":0.276140034198761},{"id":"https://openalex.org/C2780783007","wikidata":"https://www.wikidata.org/wiki/Q181923","display_name":"Attention deficit hyperactivity disorder","level":2,"score":0.25756752490997314},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.18753865361213684}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000697","descriptor_name":"Central Nervous System Stimulants","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D003342","descriptor_name":"Corpus Striatum","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D003342","descriptor_name":"Corpus Striatum","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008774","descriptor_name":"Methylphenidate","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D009434","descriptor_name":"Neural Pathways","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D009434","descriptor_name":"Neural Pathways","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D012146","descriptor_name":"Rest","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D013788","descriptor_name":"Thalamus","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D013788","descriptor_name":"Thalamus","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059907","descriptor_name":"Functional Neuroimaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D064368","descriptor_name":"Healthy Volunteers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1017/s1461145714000674","doi":"https://doi.org/10.1017/s1461145714000674","is_oa":true,"landing_page_url":"https://doi.org/10.1017/s1461145714000674","pdf_url":"https://academic.oup.com/ijnp/article-pdf/17/8/1177/17487140/17-8-1177.pdf","source":{"id":"https://openalex.org/S199972112","display_name":"The International Journal of Neuropsychopharmacology","issn_l":"1461-1457","issn":["1461-1457","1469-5111"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311647","host_organization_name":"University of Oxford","host_organization_lineage":["https://openalex.org/P4310311647"],"host_organization_lineage_names":["University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The International Journal of Neuropsychopharmacology","raw_type":"journal-article"},{"id":"pmid:24825078","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24825078","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The international journal of neuropsychopharmacology","raw_type":"Controlled Clinical Trial"},{"id":"pmh:oai:pubmedcentral.nih.gov:4506752","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4506752","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Int J Neuropsychopharmacol","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1017/s1461145714000674","doi":"https://doi.org/10.1017/s1461145714000674","is_oa":true,"landing_page_url":"https://doi.org/10.1017/s1461145714000674","pdf_url":"https://academic.oup.com/ijnp/article-pdf/17/8/1177/17487140/17-8-1177.pdf","source":{"id":"https://openalex.org/S199972112","display_name":"The International Journal of Neuropsychopharmacology","issn_l":"1461-1457","issn":["1461-1457","1469-5111"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311647","host_organization_name":"University of Oxford","host_organization_lineage":["https://openalex.org/P4310311647"],"host_organization_lineage_names":["University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The International Journal of Neuropsychopharmacology","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.98580002784729,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/clinical-trial","display_name":"Clinical Trial"}],"awards":[{"id":"https://openalex.org/G2898158542","display_name":"Thalamic Processes of Self Control in Cocaine Dependence","funder_award_id":"R21DA026998","funder_id":"https://openalex.org/F4320337347","funder_display_name":"National Institute on Drug Abuse"},{"id":"https://openalex.org/G3374096583","display_name":"Amygdala Processes and Early Habitual Drinking","funder_award_id":"R21AA018004","funder_id":"https://openalex.org/F4320337330","funder_display_name":"National Institute on Alcohol Abuse and Alcoholism"},{"id":"https://openalex.org/G3985476273","display_name":"Cerebral Correlates of Early Habitual Drinking","funder_award_id":"R01AA021449","funder_id":"https://openalex.org/F4320337330","funder_display_name":"National Institute on Alcohol Abuse and Alcoholism"},{"id":"https://openalex.org/G4468771943","display_name":"Patient-Oriented Research and Mentoring in the Translational Neurobiology/Genetic","funder_award_id":"K24DA017899","funder_id":"https://openalex.org/F4320337347","funder_display_name":"National Institute on Drug Abuse"},{"id":"https://openalex.org/G4699762618","display_name":"Cognitive control and cocaine dependence: thalamic noradrenergic processes","funder_award_id":"R01DA023248","funder_id":"https://openalex.org/F4320337347","funder_display_name":"National Institute on Drug Abuse"},{"id":"https://openalex.org/G5692938571","display_name":"Translational Research of Cocaine, Striatum, and Impulsivities","funder_award_id":"P20DA027844","funder_id":"https://openalex.org/F4320337347","funder_display_name":"National Institute on Drug Abuse"},{"id":"https://openalex.org/G6796898790","display_name":"Imaging Cognitive Control in Cocaine Dependence","funder_award_id":"K02DA026990","funder_id":"https://openalex.org/F4320337347","funder_display_name":"National Institute on Drug Abuse"},{"id":"https://openalex.org/G8587526078","display_name":null,"funder_award_id":"P20DA027844","funder_id":"https://openalex.org/F4320311440","funder_display_name":"National Alliance for Research on Schizophrenia and Depression"},{"id":"https://openalex.org/G9000897817","display_name":"Neurobiology of Cortical Systems","funder_award_id":"T32NS007224","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"}],"funders":[{"id":"https://openalex.org/F4320308380","display_name":"Yale University","ror":"https://ror.org/03v76x132"},{"id":"https://openalex.org/F4320311440","display_name":"National Alliance for Research on Schizophrenia and Depression","ror":"https://ror.org/03a63f080"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337330","display_name":"National Institute on Alcohol Abuse and Alcoholism","ror":"https://ror.org/02jzrsm59"},{"id":"https://openalex.org/F4320337347","display_name":"National Institute on Drug Abuse","ror":"https://ror.org/00fq5cm18"},{"id":"https://openalex.org/F4320337359","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2103784428.pdf","grobid_xml":"https://content.openalex.org/works/W2103784428.grobid-xml"},"referenced_works_count":133,"referenced_works":["https://openalex.org/W44091691","https://openalex.org/W76515229","https://openalex.org/W81520806","https://openalex.org/W1538570794","https://openalex.org/W1564625478","https://openalex.org/W1577449555","https://openalex.org/W1760829075","https://openalex.org/W1763543692","https://openalex.org/W1886029756","https://openalex.org/W1904647953","https://openalex.org/W1914669721","https://openalex.org/W1949474745","https://openalex.org/W1965325756","https://openalex.org/W1966328309","https://openalex.org/W1967629764","https://openalex.org/W1968866908","https://openalex.org/W1969533226","https://openalex.org/W1970695058","https://openalex.org/W1973541229","https://openalex.org/W1973909957","https://openalex.org/W1977587894","https://openalex.org/W1979315060","https://openalex.org/W1979376494","https://openalex.org/W1987638762","https://openalex.org/W1987777969","https://openalex.org/W1988581447","https://openalex.org/W1989072702","https://openalex.org/W1989978280","https://openalex.org/W1992067243","https://openalex.org/W1995320576","https://openalex.org/W1995920481","https://openalex.org/W1995992264","https://openalex.org/W1997058867","https://openalex.org/W1998689450","https://openalex.org/W1999562335","https://openalex.org/W1999961963","https://openalex.org/W2003927165","https://openalex.org/W2003996864","https://openalex.org/W2005230244","https://openalex.org/W2005728515","https://openalex.org/W2006312249","https://openalex.org/W2009494091","https://openalex.org/W2011700455","https://openalex.org/W2012069883","https://openalex.org/W2012459102","https://openalex.org/W2015075619","https://openalex.org/W2016519439","https://openalex.org/W2018418849","https://openalex.org/W2019161608","https://openalex.org/W2020470768","https://openalex.org/W2024780090","https://openalex.org/W2025299152","https://openalex.org/W2026367246","https://openalex.org/W2027473195","https://openalex.org/W2028985692","https://openalex.org/W2034630192","https://openalex.org/W2039726862","https://openalex.org/W2040847356","https://openalex.org/W2043803755","https://openalex.org/W2043977660","https://openalex.org/W2044290920","https://openalex.org/W2044333499","https://openalex.org/W2044489210","https://openalex.org/W2045118554","https://openalex.org/W2047201450","https://openalex.org/W2047751255","https://openalex.org/W2047992862","https://openalex.org/W2048014538","https://openalex.org/W2052094038","https://openalex.org/W2052400310","https://openalex.org/W2052643285","https://openalex.org/W2054121225","https://openalex.org/W2055710528","https://openalex.org/W2057760214","https://openalex.org/W2058046532","https://openalex.org/W2064831801","https://openalex.org/W2065042084","https://openalex.org/W2065292719","https://openalex.org/W2067282805","https://openalex.org/W2068403333","https://openalex.org/W2068627201","https://openalex.org/W2068628977","https://openalex.org/W2071256705","https://openalex.org/W2072580777","https://openalex.org/W2072773125","https://openalex.org/W2073330852","https://openalex.org/W2074654724","https://openalex.org/W2079289698","https://openalex.org/W2079365570","https://openalex.org/W2081718320","https://openalex.org/W2081755725","https://openalex.org/W2082714165","https://openalex.org/W2083585583","https://openalex.org/W2085971650","https://openalex.org/W2086043714","https://openalex.org/W2089244139","https://openalex.org/W2090394675","https://openalex.org/W2090664493","https://openalex.org/W2091044274","https://openalex.org/W2091108618","https://openalex.org/W2095768191","https://openalex.org/W2098929889","https://openalex.org/W2102039891","https://openalex.org/W2106367437","https://openalex.org/W2107360535","https://openalex.org/W2110429782","https://openalex.org/W2113237664","https://openalex.org/W2113620950","https://openalex.org/W2113720166","https://openalex.org/W2116647777","https://openalex.org/W2117277050","https://openalex.org/W2120182640","https://openalex.org/W2124384418","https://openalex.org/W2128472904","https://openalex.org/W2133903921","https://openalex.org/W2135475851","https://openalex.org/W2138184969","https://openalex.org/W2143756634","https://openalex.org/W2144427015","https://openalex.org/W2146853248","https://openalex.org/W2147379045","https://openalex.org/W2148301354","https://openalex.org/W2150720416","https://openalex.org/W2152502378","https://openalex.org/W2156915655","https://openalex.org/W2157643754","https://openalex.org/W2162467131","https://openalex.org/W2162555052","https://openalex.org/W2168479261","https://openalex.org/W2169787465","https://openalex.org/W2171841333","https://openalex.org/W2740215628","https://openalex.org/W2907094185"],"related_works":["https://openalex.org/W2335976779","https://openalex.org/W1957729532","https://openalex.org/W4283816148","https://openalex.org/W3016438097","https://openalex.org/W2147055598","https://openalex.org/W2904598629","https://openalex.org/W2529950287","https://openalex.org/W4405324533","https://openalex.org/W2946359930","https://openalex.org/W2526521822"],"abstract_inverted_index":{"By":[0],"blocking":[1],"dopamine":[2],"and":[3,10,49,56,77,99,111,131,176,180],"norepinephrine":[4],"transporters,":[5],"methylphenidate":[6,40,96,121,162],"affects":[7],"cognitive":[8],"performance":[9],"regional":[11],"brain":[12,34,164],"activation":[13],"in":[14],"healthy":[15,75],"individuals":[16],"as":[17,19,59,61],"well":[18,60],"those":[20],"with":[21,53,106],"neuropsychiatric":[22],"disorders.":[23],"Resting-state":[24],"connectivity":[25,44,80,101,126,138],"evaluates":[26],"the":[27,46,103,128,145,158,174],"functional":[28,43],"integrity":[29],"of":[30,33,45,153,157,161,173,178],"a":[31,67,154],"network":[32],"regions.":[35],"Here,":[36],"we":[37],"examined":[38],"how":[39],"effects":[41,160],"resting-state":[42,79],"dorsal":[47],"striatum":[48,105],"thalamus,":[50],"areas":[51,114],"each":[52],"dense":[54],"dopaminergic":[55],"noradrenergic":[57],"innervations,":[58],"global":[62,100],"cerebral":[63],"connectivity.":[64],"We":[65],"administered":[66],"single,":[68],"oral":[69],"dose":[70],"(45":[71],"mg)":[72],"to":[73,81,127],"24":[74,82],"adults":[76,85],"compared":[78],"demographically":[83],"matched":[84],"who":[86],"did":[87],"not":[88],"receive":[89],"any":[90],"medication.":[91],"The":[92,166],"results":[93,167],"showed":[94],"that":[95,183],"alters":[97],"seed-based":[98],"between":[102],"thalamus/dorsal":[104],"primary":[107],"motor":[108,129],"cortex,":[109],"amygdala/hippocampus":[110],"frontal":[112],"executive":[113],"(p":[115],"<":[116],"0.05,":[117],"corrected).":[118],"Specifically,":[119],"while":[120],"at":[122],"this":[123],"dosage":[124],"enhances":[125],"cortex":[130],"memory":[132],"circuits,":[133],"it":[134],"dampens":[135],"prefrontal":[136],"cortical":[137],"perhaps":[139],"by":[140],"increasing":[141],"catecholaminergic":[142,185],"signalling":[143],"past":[144],"'optimal'":[146],"level.":[147],"These":[148],"findings":[149],"advance":[150],"our":[151],"understanding":[152],"critical":[155],"aspect":[156],"multifaceted":[159],"on":[163],"functions.":[165],"may":[168],"also":[169],"facilitate":[170],"future":[171],"studies":[172],"aetiology":[175],"treatment":[177],"neurological":[179],"psychiatric":[181],"disorders":[182],"implicate":[184],"dysfunction.":[186]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":6},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":9},{"year":2017,"cited_by_count":8},{"year":2016,"cited_by_count":11},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}