{"id":"https://openalex.org/W2103673860","doi":"https://doi.org/10.1017/s0950268808001076","title":"Molecular analysis of high-level ciprofloxacin resistance in Salmonella enterica serovar Typhi and S. Paratyphi A: need to expand the QRDR region?","display_name":"Molecular analysis of high-level ciprofloxacin resistance in Salmonella enterica serovar Typhi and S. Paratyphi A: need to expand the QRDR region?","publication_year":2008,"publication_date":"2008-08-08","ids":{"openalex":"https://openalex.org/W2103673860","doi":"https://doi.org/10.1017/s0950268808001076","mag":"2103673860","pmid":"https://pubmed.ncbi.nlm.nih.gov/18687156"},"language":"en","primary_location":{"id":"doi:10.1017/s0950268808001076","doi":"https://doi.org/10.1017/s0950268808001076","is_oa":true,"landing_page_url":"https://doi.org/10.1017/s0950268808001076","pdf_url":"https://www.cambridge.org/core/services/aop-cambridge-core/content/view/E33AC229B4D8FCE5FA148B4A4074A9B1/S0950268808001076a.pdf/div-class-title-molecular-analysis-of-high-level-ciprofloxacin-resistance-in-span-class-italic-salmonella-enterica-span-serovar-typhi-and-span-class-italic-s-span-paratyphi-a-need-to-expand-the-qrdr-region-div.pdf","source":{"id":"https://openalex.org/S61175029","display_name":"Epidemiology and Infection","issn_l":"0950-2688","issn":["0950-2688","1469-4409"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311721","host_organization_name":"Cambridge University Press","host_organization_lineage":["https://openalex.org/P4310311721","https://openalex.org/P4310311702"],"host_organization_lineage_names":["Cambridge University Press","University of Cambridge"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Epidemiology and Infection","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.cambridge.org/core/services/aop-cambridge-core/content/view/E33AC229B4D8FCE5FA148B4A4074A9B1/S0950268808001076a.pdf/div-class-title-molecular-analysis-of-high-level-ciprofloxacin-resistance-in-span-class-italic-salmonella-enterica-span-serovar-typhi-and-span-class-italic-s-span-paratyphi-a-need-to-expand-the-qrdr-region-div.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5047362117","display_name":"Malini Rajinder Capoor","orcid":"https://orcid.org/0000-0001-8423-0505","observed_orcids":["https://orcid.org/0000-0001-8423-0505"]},"institutions":[{"id":"https://openalex.org/I1312996466","display_name":"Safdarjang Hospital","ror":"https://ror.org/0267zkr58","country_code":"IN","type":"healthcare","lineage":["https://openalex.org/I1312996466"]},{"id":"https://openalex.org/I17972996","display_name":"Vardhman Mahavir Medical College & Safdarjung Hospital","ror":"https://ror.org/03zj0ps89","country_code":"IN","type":"healthcare","lineage":["https://openalex.org/I17972996"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"M. R. CAPOOR","raw_affiliation_strings":["Department of Microbiology, Vardhman Mahaveer Medical College and Safdarjung Hospital, New Delhi, India","Department of Microbiology, Vardhman Mahaveer Medical College & Safdarjung Hospital, New Delhi, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology, Vardhman Mahaveer Medical College and Safdarjung Hospital, New Delhi, India","institution_ids":["https://openalex.org/I1312996466","https://openalex.org/I17972996"]},{"raw_affiliation_string":"Department of Microbiology, Vardhman Mahaveer Medical College & Safdarjung Hospital, New Delhi, India","institution_ids":["https://openalex.org/I1312996466","https://openalex.org/I17972996"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086329442","display_name":"Deepthi Nair","orcid":"https://orcid.org/0000-0002-0081-4034","observed_orcids":["https://orcid.org/0000-0002-0081-4034"]},"institutions":[{"id":"https://openalex.org/I1312996466","display_name":"Safdarjang Hospital","ror":"https://ror.org/0267zkr58","country_code":"IN","type":"healthcare","lineage":["https://openalex.org/I1312996466"]},{"id":"https://openalex.org/I17972996","display_name":"Vardhman Mahavir Medical College & Safdarjung Hospital","ror":"https://ror.org/03zj0ps89","country_code":"IN","type":"healthcare","lineage":["https://openalex.org/I17972996"]}],"countries":["IN"],"is_corresponding":true,"raw_author_name":"D. NAIR","raw_affiliation_strings":["Department of Microbiology, Vardhman Mahaveer Medical College and Safdarjung Hospital, New Delhi, India","Department of Microbiology, Vardhman Mahaveer Medical College & Safdarjung Hospital, New Delhi, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology, Vardhman Mahaveer Medical College and Safdarjung Hospital, New Delhi, India","institution_ids":["https://openalex.org/I1312996466","https://openalex.org/I17972996"]},{"raw_affiliation_string":"Department of Microbiology, Vardhman Mahaveer Medical College & Safdarjung Hospital, New Delhi, India","institution_ids":["https://openalex.org/I1312996466","https://openalex.org/I17972996"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050789757","display_name":"N. S. WALIA","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1312996466","display_name":"Safdarjang Hospital","ror":"https://ror.org/0267zkr58","country_code":"IN","type":"healthcare","lineage":["https://openalex.org/I1312996466"]},{"id":"https://openalex.org/I17972996","display_name":"Vardhman Mahavir Medical College & Safdarjung Hospital","ror":"https://ror.org/03zj0ps89","country_code":"IN","type":"healthcare","lineage":["https://openalex.org/I17972996"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"N. S. WALIA","raw_affiliation_strings":["Department of Microbiology, Vardhman Mahaveer Medical College and Safdarjung Hospital, New Delhi, India","Department of Microbiology, Vardhman Mahaveer Medical College & Safdarjung Hospital, New Delhi, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology, Vardhman Mahaveer Medical College and Safdarjung Hospital, New Delhi, India","institution_ids":["https://openalex.org/I1312996466","https://openalex.org/I17972996"]},{"raw_affiliation_string":"Department of Microbiology, Vardhman Mahaveer Medical College & Safdarjung Hospital, New Delhi, India","institution_ids":["https://openalex.org/I1312996466","https://openalex.org/I17972996"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063255269","display_name":"R. S. ROUTELA","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I103004294","display_name":"National Center for Disease Control","ror":"https://ror.org/01ks7f963","country_code":"IN","type":"government","lineage":["https://openalex.org/I103004294","https://openalex.org/I2799351866","https://openalex.org/I4210148677"]},{"id":"https://openalex.org/I3141573830","display_name":"Department of Biotechnology","ror":"https://ror.org/03tjsyq23","country_code":"IN","type":"government","lineage":["https://openalex.org/I2799351866","https://openalex.org/I3141573830","https://openalex.org/I4210134808"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"R. S. ROUTELA","raw_affiliation_strings":["Department of Biotechnology, National Institute of Communicable Diseases, New Delhi, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biotechnology, National Institute of Communicable Diseases, New Delhi, India","institution_ids":["https://openalex.org/I103004294","https://openalex.org/I3141573830"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076453504","display_name":"Shyam Sunder Grover","orcid":"https://orcid.org/0000-0002-2467-4689","observed_orcids":["https://orcid.org/0000-0002-2467-4689"]},"institutions":[{"id":"https://openalex.org/I103004294","display_name":"National Center for Disease Control","ror":"https://ror.org/01ks7f963","country_code":"IN","type":"government","lineage":["https://openalex.org/I103004294","https://openalex.org/I2799351866","https://openalex.org/I4210148677"]},{"id":"https://openalex.org/I3141573830","display_name":"Department of Biotechnology","ror":"https://ror.org/03tjsyq23","country_code":"IN","type":"government","lineage":["https://openalex.org/I2799351866","https://openalex.org/I3141573830","https://openalex.org/I4210134808"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"S. S. GROVER","raw_affiliation_strings":["Department of Biotechnology, National Institute of Communicable Diseases, New Delhi, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biotechnology, National Institute of Communicable Diseases, New Delhi, India","institution_ids":["https://openalex.org/I103004294","https://openalex.org/I3141573830"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110163714","display_name":"M Deb","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1312996466","display_name":"Safdarjang Hospital","ror":"https://ror.org/0267zkr58","country_code":"IN","type":"healthcare","lineage":["https://openalex.org/I1312996466"]},{"id":"https://openalex.org/I17972996","display_name":"Vardhman Mahavir Medical College & Safdarjung Hospital","ror":"https://ror.org/03zj0ps89","country_code":"IN","type":"healthcare","lineage":["https://openalex.org/I17972996"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"M. DEB","raw_affiliation_strings":["Department of Microbiology, Vardhman Mahaveer Medical College and Safdarjung Hospital, New Delhi, India","Department of Microbiology, Vardhman Mahaveer Medical College & Safdarjung Hospital, New Delhi, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology, Vardhman Mahaveer Medical College and Safdarjung Hospital, New Delhi, India","institution_ids":["https://openalex.org/I1312996466","https://openalex.org/I17972996"]},{"raw_affiliation_string":"Department of Microbiology, Vardhman Mahaveer Medical College & Safdarjung Hospital, New Delhi, India","institution_ids":["https://openalex.org/I1312996466","https://openalex.org/I17972996"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082094552","display_name":"Praveen Aggarwal","orcid":"https://orcid.org/0000-0003-0702-6441","observed_orcids":["https://orcid.org/0000-0003-0702-6441"]},"institutions":[{"id":"https://openalex.org/I1312996466","display_name":"Safdarjang Hospital","ror":"https://ror.org/0267zkr58","country_code":"IN","type":"healthcare","lineage":["https://openalex.org/I1312996466"]},{"id":"https://openalex.org/I17972996","display_name":"Vardhman Mahavir Medical College & Safdarjung Hospital","ror":"https://ror.org/03zj0ps89","country_code":"IN","type":"healthcare","lineage":["https://openalex.org/I17972996"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"P. AGGARWAL","raw_affiliation_strings":["Department of Microbiology, Vardhman Mahaveer Medical College and Safdarjung Hospital, New Delhi, India","Department of Microbiology, Vardhman Mahaveer Medical College & Safdarjung Hospital, New Delhi, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology, Vardhman Mahaveer Medical College and Safdarjung Hospital, New Delhi, India","institution_ids":["https://openalex.org/I1312996466","https://openalex.org/I17972996"]},{"raw_affiliation_string":"Department of Microbiology, Vardhman Mahaveer Medical College & Safdarjung Hospital, New Delhi, India","institution_ids":["https://openalex.org/I1312996466","https://openalex.org/I17972996"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110108186","display_name":"P K Pillai","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"P. K. PILLAI","raw_affiliation_strings":["Department of Microbiology, Majeedia Hospital, New Delhi, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology, Majeedia Hospital, New Delhi, India","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5067288236","display_name":"Pablo Juan Bifani","orcid":"https://orcid.org/0000-0001-9651-6439","observed_orcids":["https://orcid.org/0000-0001-9651-6439"]},"institutions":[{"id":"https://openalex.org/I4405271293","display_name":"Les Amis des Instituts Pasteur \u00e0 Bruxelles","ror":"https://ror.org/026wyqd33","country_code":"BE","type":"nonprofit","lineage":["https://openalex.org/I4405271293"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"P. J. BIFANI","raw_affiliation_strings":["Department of Molecular Biology, Pasteur Institute, Brussels, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Biology, Pasteur Institute, Brussels, Belgium","institution_ids":["https://openalex.org/I4405271293"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5086329442"],"corresponding_institution_ids":["https://openalex.org/I1312996466","https://openalex.org/I17972996"],"apc_list":{"value":3550,"currency":"USD","value_usd":3550},"apc_paid":null,"fwci":1.1876,"has_fulltext":true,"cited_by_count":20,"citation_normalized_percentile":{"value":0.78286715,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":98},"biblio":{"volume":"137","issue":"6","first_page":"871","last_page":"878"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10486","display_name":"Salmonella and Campylobacter epidemiology","score":0.676800012588501,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10486","display_name":"Salmonella and Campylobacter epidemiology","score":0.676800012588501,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10147","display_name":"Antibiotic Resistance in Bacteria","score":0.3131999969482422,"subfield":{"id":"https://openalex.org/subfields/2726","display_name":"Microbiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10120","display_name":"Bacterial Genetics and Biotechnology","score":0.003000000026077032,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ciprofloxacin-resistance","display_name":"ciprofloxacin resistance","score":0.9980000257492065},{"id":"https://openalex.org/keywords/salmonella-enterica-serovar-typhi","display_name":"Salmonella typhi","score":0.9390000104904175},{"id":"https://openalex.org/keywords/salmonella-paratyphi-a","display_name":"Salmonella Paratyphi A","score":1.0},{"id":"https://openalex.org/keywords/fluoroquinolone-resistance","display_name":"fluoroquinolone resistance","score":0.8769999742507935},{"id":"https://openalex.org/keywords/gyra-mutations","display_name":"gyrA mutations","score":0.8859999775886536},{"id":"https://openalex.org/keywords/quinolone-resistance-determining-region","display_name":"quinolone resistance-determining region","score":0.8970000147819519},{"id":"https://openalex.org/keywords/enteric-fever","display_name":"enteric fever","score":0.7749999761581421},{"id":"https://openalex.org/keywords/antimicrobial-resistance-surveillance","display_name":"antimicrobial resistance surveillance","score":0.9020000100135803}],"concepts":[{"id":"https://openalex.org/C2778512257","wikidata":"https://www.wikidata.org/wiki/Q256602","display_name":"Ciprofloxacin","level":3,"score":0.9087119698524475},{"id":"https://openalex.org/C2779922871","wikidata":"https://www.wikidata.org/wiki/Q426549","display_name":"Quinolone","level":3,"score":0.7299689054489136},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.6940507888793945},{"id":"https://openalex.org/C2994552716","wikidata":"https://www.wikidata.org/wiki/Q21600865","display_name":"Salmonella typhi","level":4,"score":0.5882593393325806},{"id":"https://openalex.org/C22744801","wikidata":"https://www.wikidata.org/wiki/Q172778","display_name":"Plasmid","level":3,"score":0.5545091032981873},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5359777808189392},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.5307215452194214},{"id":"https://openalex.org/C176947019","wikidata":"https://www.wikidata.org/wiki/Q597889","display_name":"Minimum inhibitory concentration","level":3,"score":0.46500691771507263},{"id":"https://openalex.org/C2779607309","wikidata":"https://www.wikidata.org/wiki/Q2264864","display_name":"Salmonella enterica","level":4,"score":0.45728227496147156},{"id":"https://openalex.org/C10389963","wikidata":"https://www.wikidata.org/wiki/Q848328","display_name":"Serotype","level":2,"score":0.4221945106983185},{"id":"https://openalex.org/C501593827","wikidata":"https://www.wikidata.org/wiki/Q12187","display_name":"Antibiotics","level":2,"score":0.3101978898048401},{"id":"https://openalex.org/C2781065037","wikidata":"https://www.wikidata.org/wiki/Q150839","display_name":"Salmonella","level":3,"score":0.30219557881355286},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.2553523778915405},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.2073170244693756},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.16112872958183289},{"id":"https://openalex.org/C547475151","wikidata":"https://www.wikidata.org/wiki/Q25419","display_name":"Escherichia coli","level":3,"score":0.13918736577033997}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000900","descriptor_name":"Anti-Bacterial Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D001426","descriptor_name":"Bacterial Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002939","descriptor_name":"Ciprofloxacin","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D004269","descriptor_name":"DNA, Bacterial","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012482","descriptor_name":"Salmonella paratyphi A","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D012482","descriptor_name":"Salmonella paratyphi A","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012485","descriptor_name":"Salmonella typhi","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D012485","descriptor_name":"Salmonella typhi","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D024881","descriptor_name":"Drug Resistance, Bacterial","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1017/s0950268808001076","doi":"https://doi.org/10.1017/s0950268808001076","is_oa":true,"landing_page_url":"https://doi.org/10.1017/s0950268808001076","pdf_url":"https://www.cambridge.org/core/services/aop-cambridge-core/content/view/E33AC229B4D8FCE5FA148B4A4074A9B1/S0950268808001076a.pdf/div-class-title-molecular-analysis-of-high-level-ciprofloxacin-resistance-in-span-class-italic-salmonella-enterica-span-serovar-typhi-and-span-class-italic-s-span-paratyphi-a-need-to-expand-the-qrdr-region-div.pdf","source":{"id":"https://openalex.org/S61175029","display_name":"Epidemiology and Infection","issn_l":"0950-2688","issn":["0950-2688","1469-4409"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311721","host_organization_name":"Cambridge University Press","host_organization_lineage":["https://openalex.org/P4310311721","https://openalex.org/P4310311702"],"host_organization_lineage_names":["Cambridge University Press","University of Cambridge"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Epidemiology and Infection","raw_type":"journal-article"},{"id":"pmid:18687156","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18687156","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Epidemiology and infection","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1017/s0950268808001076","doi":"https://doi.org/10.1017/s0950268808001076","is_oa":true,"landing_page_url":"https://doi.org/10.1017/s0950268808001076","pdf_url":"https://www.cambridge.org/core/services/aop-cambridge-core/content/view/E33AC229B4D8FCE5FA148B4A4074A9B1/S0950268808001076a.pdf/div-class-title-molecular-analysis-of-high-level-ciprofloxacin-resistance-in-span-class-italic-salmonella-enterica-span-serovar-typhi-and-span-class-italic-s-span-paratyphi-a-need-to-expand-the-qrdr-region-div.pdf","source":{"id":"https://openalex.org/S61175029","display_name":"Epidemiology and Infection","issn_l":"0950-2688","issn":["0950-2688","1469-4409"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311721","host_organization_name":"Cambridge University Press","host_organization_lineage":["https://openalex.org/P4310311721","https://openalex.org/P4310311702"],"host_organization_lineage_names":["Cambridge University Press","University of Cambridge"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Epidemiology and Infection","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.8371999859809875}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2103673860.pdf","grobid_xml":"https://content.openalex.org/works/W2103673860.grobid-xml"},"referenced_works_count":26,"referenced_works":["https://openalex.org/W1583686009","https://openalex.org/W1813874952","https://openalex.org/W1990810367","https://openalex.org/W1994128614","https://openalex.org/W2009050559","https://openalex.org/W2015370265","https://openalex.org/W2015701752","https://openalex.org/W2056533174","https://openalex.org/W2062404668","https://openalex.org/W2063861000","https://openalex.org/W2089844697","https://openalex.org/W2090669537","https://openalex.org/W2098533214","https://openalex.org/W2106142562","https://openalex.org/W2107494940","https://openalex.org/W2108187249","https://openalex.org/W2114877749","https://openalex.org/W2134693455","https://openalex.org/W2135393889","https://openalex.org/W2135453488","https://openalex.org/W2142876783","https://openalex.org/W2144409508","https://openalex.org/W2157944339","https://openalex.org/W2161358632","https://openalex.org/W2164286345","https://openalex.org/W2166432060"],"related_works":["https://openalex.org/W2134693455","https://openalex.org/W2056533174","https://openalex.org/W1993872491","https://openalex.org/W2185420703","https://openalex.org/W7161803148","https://openalex.org/W7098012289","https://openalex.org/W2520050909","https://openalex.org/W2024558829","https://openalex.org/W1688566826","https://openalex.org/W2009050559"],"abstract_inverted_index":{"Fourteen":[0],"strains":[1,20,104],"of":[2,24,92,129,141,148],"S.":[3,7,41,46],"Typhi":[4,42],"(n=13)":[5],"and":[6,28,35,43,57,86,137],"Paratyphi":[8,47],"A":[9,48],"(n=1)":[10],"resistant":[11],"to":[12],"ciprofloxacin":[13,18],"were":[14,71,115],"compared":[15],"with":[16,95,126],"30":[17,93],"decreased-susceptibility":[19,121],"on":[21],"the":[22,62,88],"basis":[23],"qnr":[25,108,112],"plasmid":[26,109],"analysis,":[27],"nucleotide":[29],"substitutions":[30],"at":[31],"gyrA,":[32],"gyrB,":[33],"parC":[34],"parE.":[36],"In":[37],"ciprofloxacin-resistant":[38,119],"strains,":[39],"five":[40],"a":[44,58],"single":[45,98],"showed":[49],"triple":[50],"mutations":[51,70],"in":[52,74,82,102,118],"gyrA":[53,83],"(Ser83-->Phe,":[54],"Asp87-->Asn,":[55],"Glu133-->Gly)":[56],"novel":[59,136],"mutation":[60,99],"outside":[61,87],"quinolone":[63],"resistance":[64,131],"determining":[65],"region":[66],"(QRDR)":[67],"(Met52-->Leu).":[68],"Novel":[69],"also":[72],"discovered":[73],"an":[75],"isolate":[76],"(minimum":[77],"inhibitory":[78],"concentration":[79],"8":[80],"microg/ml)":[81],"gene":[84],"Asp76-->Asn":[85],"QRDR":[89],"Leu44-->Ile.":[90],"Out":[91],"isolates":[94],"reduced":[96],"susceptibility,":[97],"was":[100],"found":[101],"12":[103],"only.":[105],"Genes":[106],"encoding":[107],"(qnr":[110],"A,":[111],"B,":[113],"AAC1-F)":[114],"not":[116],"detected":[117],"or":[120],"strains.":[122],"Antimicrobial":[123],"surveillance":[124],"coupled":[125],"molecular":[127,139],"analysis":[128],"fluoroquinolone":[130],"is":[132,144],"warranted":[133],"for":[134,146],"reconfirming":[135],"established":[138],"patterns":[140],"resistance,":[142],"which":[143],"quintessential":[145],"reappraisal":[147],"enteric":[149],"fever":[150],"therapeutics.":[151]},"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":5},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}