{"id":"https://openalex.org/W2103649226","doi":"https://doi.org/10.3390/molecules190913990","title":"A Galactose-Binding Lectin Isolated from Aplysia kurodai (Sea Hare) Eggs Inhibits Streptolysin-Induced Hemolysis","display_name":"A Galactose-Binding Lectin Isolated from Aplysia kurodai (Sea Hare) Eggs Inhibits Streptolysin-Induced Hemolysis","publication_year":2014,"publication_date":"2014-09-05","ids":{"openalex":"https://openalex.org/W2103649226","doi":"https://doi.org/10.3390/molecules190913990","mag":"2103649226","pmid":"https://pubmed.ncbi.nlm.nih.gov/25197935","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6271371"},"language":"en","primary_location":{"id":"doi:10.3390/molecules190913990","doi":"https://doi.org/10.3390/molecules190913990","is_oa":true,"landing_page_url":"https://doi.org/10.3390/molecules190913990","pdf_url":"https://www.mdpi.com/1420-3049/19/9/13990/pdf?version=1453472702","source":{"id":"https://openalex.org/S108911230","display_name":"Molecules","issn_l":"1420-3049","issn":["1420-3049","1433-1373"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","medline","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecules","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/1420-3049/19/9/13990/pdf?version=1453472702","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5019942660","display_name":"Imtiaj Hasan","orcid":"https://orcid.org/0000-0002-4715-9022","observed_orcids":["https://orcid.org/0000-0002-4715-9022"]},"institutions":[{"id":"https://openalex.org/I89630735","display_name":"Yokohama City University","ror":"https://ror.org/0135d1r83","country_code":"JP","type":"education","lineage":["https://openalex.org/I89630735"]},{"id":"https://openalex.org/I902853133","display_name":"University of Rajshahi","ror":"https://ror.org/05nnyr510","country_code":"BD","type":"education","lineage":["https://openalex.org/I902853133"]}],"countries":["BD","JP"],"is_corresponding":false,"raw_author_name":"Imtiaj Hasan","raw_affiliation_strings":["Department of Biochemistry and Molecular Biology, Faculty of Science, University of Rajshahi, Rajshahi-6205, Bangladesh","Laboratories of Glycobiology & Marine Biochemistry and Molecular Toxicology, Department of Life and Environmental System Science, Graduate School of NanoBio Sciences, Yokohama City University, 22-2 Seto, Kanazawa-ku, Yokohama 236-0027, Japan"],"raw_orcid":"https://orcid.org/0000-0002-4715-9022","affiliations":[{"raw_affiliation_string":"Department of Biochemistry and Molecular Biology, Faculty of Science, University of Rajshahi, Rajshahi-6205, Bangladesh","institution_ids":["https://openalex.org/I902853133"]},{"raw_affiliation_string":"Laboratories of Glycobiology & Marine Biochemistry and Molecular Toxicology, Department of Life and Environmental System Science, Graduate School of NanoBio Sciences, Yokohama City University, 22-2 Seto, Kanazawa-ku, Yokohama 236-0027, Japan","institution_ids":["https://openalex.org/I89630735"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015627169","display_name":"Miharu Watanabe","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I57361664","display_name":"Azabu University","ror":"https://ror.org/00wzjq897","country_code":"JP","type":"education","lineage":["https://openalex.org/I57361664"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Miharu Watanabe","raw_affiliation_strings":["School of Life and Environmental Science, Azabu University, 1-17-71, Fuchinobe, Chuo-ku, Sagamihara, Kanagawa 252-5201, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Life and Environmental Science, Azabu University, 1-17-71, Fuchinobe, Chuo-ku, Sagamihara, Kanagawa 252-5201, Japan","institution_ids":["https://openalex.org/I57361664"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Naoto Ishizaki","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I57361664","display_name":"Azabu University","ror":"https://ror.org/00wzjq897","country_code":"JP","type":"education","lineage":["https://openalex.org/I57361664"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Naoto Ishizaki","raw_affiliation_strings":["School of Life and Environmental Science, Azabu University, 1-17-71, Fuchinobe, Chuo-ku, Sagamihara, Kanagawa 252-5201, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Life and Environmental Science, Azabu University, 1-17-71, Fuchinobe, Chuo-ku, Sagamihara, Kanagawa 252-5201, Japan","institution_ids":["https://openalex.org/I57361664"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113946351","display_name":"Yoshiko Sugita\u2010Konishi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I57361664","display_name":"Azabu University","ror":"https://ror.org/00wzjq897","country_code":"JP","type":"education","lineage":["https://openalex.org/I57361664"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yoshiko Sugita-Konishi","raw_affiliation_strings":["School of Life and Environmental Science, Azabu University, 1-17-71, Fuchinobe, Chuo-ku, Sagamihara, Kanagawa 252-5201, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Life and Environmental Science, Azabu University, 1-17-71, Fuchinobe, Chuo-ku, Sagamihara, Kanagawa 252-5201, Japan","institution_ids":["https://openalex.org/I57361664"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103536997","display_name":"Yasushi Kawakami","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I57361664","display_name":"Azabu University","ror":"https://ror.org/00wzjq897","country_code":"JP","type":"education","lineage":["https://openalex.org/I57361664"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yasushi Kawakami","raw_affiliation_strings":["School of Life and Environmental Science, Azabu University, 1-17-71, Fuchinobe, Chuo-ku, Sagamihara, Kanagawa 252-5201, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Life and Environmental Science, Azabu University, 1-17-71, Fuchinobe, Chuo-ku, Sagamihara, Kanagawa 252-5201, Japan","institution_ids":["https://openalex.org/I57361664"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069082772","display_name":"Jun Suzuki","orcid":"https://orcid.org/0000-0002-5441-9486","observed_orcids":["https://orcid.org/0000-0002-5441-9486"]},"institutions":[{"id":"https://openalex.org/I57361664","display_name":"Azabu University","ror":"https://ror.org/00wzjq897","country_code":"JP","type":"education","lineage":["https://openalex.org/I57361664"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Jun Suzuki","raw_affiliation_strings":["School of Life and Environmental Science, Azabu University, 1-17-71, Fuchinobe, Chuo-ku, Sagamihara, Kanagawa 252-5201, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Life and Environmental Science, Azabu University, 1-17-71, Fuchinobe, Chuo-ku, Sagamihara, Kanagawa 252-5201, Japan","institution_ids":["https://openalex.org/I57361664"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081897353","display_name":"Chikaku Dogasaki","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I57361664","display_name":"Azabu University","ror":"https://ror.org/00wzjq897","country_code":"JP","type":"education","lineage":["https://openalex.org/I57361664"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Chikaku Dogasaki","raw_affiliation_strings":["School of Life and Environmental Science, Azabu University, 1-17-71, Fuchinobe, Chuo-ku, Sagamihara, Kanagawa 252-5201, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Life and Environmental Science, Azabu University, 1-17-71, Fuchinobe, Chuo-ku, Sagamihara, Kanagawa 252-5201, Japan","institution_ids":["https://openalex.org/I57361664"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064225623","display_name":"Sultana Rajia","orcid":"https://orcid.org/0000-0003-2239-9625","observed_orcids":["https://orcid.org/0000-0003-2239-9625"]},"institutions":[{"id":"https://openalex.org/I3132220783","display_name":"Varendra University","ror":"https://ror.org/00crqck26","country_code":"BD","type":"education","lineage":["https://openalex.org/I3132220783"]},{"id":"https://openalex.org/I89630735","display_name":"Yokohama City University","ror":"https://ror.org/0135d1r83","country_code":"JP","type":"education","lineage":["https://openalex.org/I89630735"]}],"countries":["BD","JP"],"is_corresponding":false,"raw_author_name":"Sultana Rajia","raw_affiliation_strings":["Department of Natural Science, Varendra University, Rajshahi-6204, Bangladesh","Laboratories of Glycobiology & Marine Biochemistry and Molecular Toxicology, Department of Life and Environmental System Science, Graduate School of NanoBio Sciences, Yokohama City University, 22-2 Seto, Kanazawa-ku, Yokohama 236-0027, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Natural Science, Varendra University, Rajshahi-6204, Bangladesh","institution_ids":["https://openalex.org/I3132220783"]},{"raw_affiliation_string":"Laboratories of Glycobiology & Marine Biochemistry and Molecular Toxicology, Department of Life and Environmental System Science, Graduate School of NanoBio Sciences, Yokohama City University, 22-2 Seto, Kanazawa-ku, Yokohama 236-0027, Japan","institution_ids":["https://openalex.org/I89630735"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032116383","display_name":"Sarkar M. A. Kawsar","orcid":"https://orcid.org/0000-0001-7964-9117","observed_orcids":["https://orcid.org/0000-0001-7964-9117"]},"institutions":[{"id":"https://openalex.org/I894293524","display_name":"University of Chittagong","ror":"https://ror.org/01173vs27","country_code":"BD","type":"education","lineage":["https://openalex.org/I894293524"]}],"countries":["BD"],"is_corresponding":false,"raw_author_name":"Sarkar Kawsar","raw_affiliation_strings":["Department of Chemistry, Faculty of Sciences, University of Chittagong, Chittagong-4331, Bangladesh"],"raw_orcid":"https://orcid.org/0000-0001-7964-9117","affiliations":[{"raw_affiliation_string":"Department of Chemistry, Faculty of Sciences, University of Chittagong, Chittagong-4331, Bangladesh","institution_ids":["https://openalex.org/I894293524"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054478383","display_name":"Yasuhiro Koide","orcid":"https://orcid.org/0000-0002-4043-9160","observed_orcids":["https://orcid.org/0000-0002-4043-9160"]},"institutions":[{"id":"https://openalex.org/I89630735","display_name":"Yokohama City University","ror":"https://ror.org/0135d1r83","country_code":"JP","type":"education","lineage":["https://openalex.org/I89630735"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yasuhiro Koide","raw_affiliation_strings":["Laboratories of Glycobiology & Marine Biochemistry and Molecular Toxicology, Department of Life and Environmental System Science, Graduate School of NanoBio Sciences, Yokohama City University, 22-2 Seto, Kanazawa-ku, Yokohama 236-0027, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratories of Glycobiology & Marine Biochemistry and Molecular Toxicology, Department of Life and Environmental System Science, Graduate School of NanoBio Sciences, Yokohama City University, 22-2 Seto, Kanazawa-ku, Yokohama 236-0027, Japan","institution_ids":["https://openalex.org/I89630735"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039475322","display_name":"Robert A. Kanaly","orcid":"https://orcid.org/0000-0002-8867-3546","observed_orcids":["https://orcid.org/0000-0002-8867-3546"]},"institutions":[{"id":"https://openalex.org/I89630735","display_name":"Yokohama City University","ror":"https://ror.org/0135d1r83","country_code":"JP","type":"education","lineage":["https://openalex.org/I89630735"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Robert Kanaly","raw_affiliation_strings":["Laboratories of Glycobiology & Marine Biochemistry and Molecular Toxicology, Department of Life and Environmental System Science, Graduate School of NanoBio Sciences, Yokohama City University, 22-2 Seto, Kanazawa-ku, Yokohama 236-0027, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratories of Glycobiology & Marine Biochemistry and Molecular Toxicology, Department of Life and Environmental System Science, Graduate School of NanoBio Sciences, Yokohama City University, 22-2 Seto, Kanazawa-ku, Yokohama 236-0027, Japan","institution_ids":["https://openalex.org/I89630735"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027716626","display_name":"Shigeki Sugawara","orcid":"https://orcid.org/0000-0001-8806-5973","observed_orcids":["https://orcid.org/0000-0001-8806-5973"]},"institutions":[{"id":"https://openalex.org/I85324120","display_name":"Tohoku Medical and Pharmaceutical University","ror":"https://ror.org/0264zxa45","country_code":"JP","type":"education","lineage":["https://openalex.org/I85324120"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Shigeki Sugawara","raw_affiliation_strings":["Division of Cell Recognition Study, Institute of Molecular Biomembrane and Glycobiology, Tohoku Pharmaceutical University, 4-4-1 Komatsushima, Aoba-ku, Sendai 981-8558, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cell Recognition Study, Institute of Molecular Biomembrane and Glycobiology, Tohoku Pharmaceutical University, 4-4-1 Komatsushima, Aoba-ku, Sendai 981-8558, Japan","institution_ids":["https://openalex.org/I85324120"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054954409","display_name":"Masahiro Hosono","orcid":"https://orcid.org/0000-0003-0663-5560","observed_orcids":["https://orcid.org/0000-0003-0663-5560"]},"institutions":[{"id":"https://openalex.org/I85324120","display_name":"Tohoku Medical and Pharmaceutical University","ror":"https://ror.org/0264zxa45","country_code":"JP","type":"education","lineage":["https://openalex.org/I85324120"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Masahiro Hosono","raw_affiliation_strings":["Division of Cell Recognition Study, Institute of Molecular Biomembrane and Glycobiology, Tohoku Pharmaceutical University, 4-4-1 Komatsushima, Aoba-ku, Sendai 981-8558, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cell Recognition Study, Institute of Molecular Biomembrane and Glycobiology, Tohoku Pharmaceutical University, 4-4-1 Komatsushima, Aoba-ku, Sendai 981-8558, Japan","institution_ids":["https://openalex.org/I85324120"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103148996","display_name":"Yukiko Ogawa","orcid":"https://orcid.org/0000-0003-1487-8079","observed_orcids":["https://orcid.org/0000-0003-1487-8079"]},"institutions":[{"id":"https://openalex.org/I21361538","display_name":"Nagasaki International University","ror":"https://ror.org/01tqqny90","country_code":"JP","type":"education","lineage":["https://openalex.org/I21361538"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yukiko Ogawa","raw_affiliation_strings":["Department of Pharmacy, Faculty of Pharmaceutical Science, Nagasaki International University, 2825-7 Huis Ten Bosch, Sasebo, Nagasaki 859-3298, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacy, Faculty of Pharmaceutical Science, Nagasaki International University, 2825-7 Huis Ten Bosch, Sasebo, Nagasaki 859-3298, Japan","institution_ids":["https://openalex.org/I21361538"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083928749","display_name":"Yuki Fujii","orcid":"https://orcid.org/0000-0001-6408-9620","observed_orcids":["https://orcid.org/0000-0001-6408-9620"]},"institutions":[{"id":"https://openalex.org/I21361538","display_name":"Nagasaki International University","ror":"https://ror.org/01tqqny90","country_code":"JP","type":"education","lineage":["https://openalex.org/I21361538"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yuki Fujii","raw_affiliation_strings":["Department of Pharmacy, Faculty of Pharmaceutical Science, Nagasaki International University, 2825-7 Huis Ten Bosch, Sasebo, Nagasaki 859-3298, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacy, Faculty of Pharmaceutical Science, Nagasaki International University, 2825-7 Huis Ten Bosch, Sasebo, Nagasaki 859-3298, Japan","institution_ids":["https://openalex.org/I21361538"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003765049","display_name":"Hideyuki Iriko","orcid":"https://orcid.org/0009-0005-9617-843X","observed_orcids":["https://orcid.org/0009-0005-9617-843X"]},"institutions":[{"id":"https://openalex.org/I65837984","display_name":"Kobe University","ror":"https://ror.org/03tgsfw79","country_code":"JP","type":"education","lineage":["https://openalex.org/I65837984"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hideyuki Iriko","raw_affiliation_strings":["Department of Parasitology, Graduate School of Health Sciences, Kobe University, 7-10-2, Tomogaoka, Suma-ku, Kobe 654-0142, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Parasitology, Graduate School of Health Sciences, Kobe University, 7-10-2, Tomogaoka, Suma-ku, Kobe 654-0142, Japan","institution_ids":["https://openalex.org/I65837984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016371237","display_name":"Jiharu Hamako","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I145673806","display_name":"Fujita Health University","ror":"https://ror.org/046f6cx68","country_code":"JP","type":"education","lineage":["https://openalex.org/I145673806"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Jiharu Hamako","raw_affiliation_strings":["Department of Biology, School of Health Sciences, Fujita Health University, Toyoake, Aichi 470-1192, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, School of Health Sciences, Fujita Health University, Toyoake, Aichi 470-1192, Japan","institution_ids":["https://openalex.org/I145673806"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040066413","display_name":"Taei Matsui","orcid":"https://orcid.org/0000-0001-6552-3935","observed_orcids":["https://orcid.org/0000-0001-6552-3935"]},"institutions":[{"id":"https://openalex.org/I145673806","display_name":"Fujita Health University","ror":"https://ror.org/046f6cx68","country_code":"JP","type":"education","lineage":["https://openalex.org/I145673806"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Taei Matsui","raw_affiliation_strings":["Department of Biology, School of Health Sciences, Fujita Health University, Toyoake, Aichi 470-1192, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, School of Health Sciences, Fujita Health University, Toyoake, Aichi 470-1192, Japan","institution_ids":["https://openalex.org/I145673806"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5078930847","display_name":"Yasuhiro Ozeki","orcid":"https://orcid.org/0000-0002-2782-6158","observed_orcids":["https://orcid.org/0000-0002-2782-6158"]},"institutions":[{"id":"https://openalex.org/I89630735","display_name":"Yokohama City University","ror":"https://ror.org/0135d1r83","country_code":"JP","type":"education","lineage":["https://openalex.org/I89630735"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Yasuhiro Ozeki","raw_affiliation_strings":["Laboratories of Glycobiology & Marine Biochemistry and Molecular Toxicology, Department of Life and Environmental System Science, Graduate School of NanoBio Sciences, Yokohama City University, 22-2 Seto, Kanazawa-ku, Yokohama 236-0027, Japan"],"raw_orcid":"https://orcid.org/0000-0002-2782-6158","affiliations":[{"raw_affiliation_string":"Laboratories of Glycobiology & Marine Biochemistry and Molecular Toxicology, Department of Life and Environmental System Science, Graduate School of NanoBio Sciences, Yokohama City University, 22-2 Seto, Kanazawa-ku, Yokohama 236-0027, Japan","institution_ids":["https://openalex.org/I89630735"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":9,"corresponding_author_ids":["https://openalex.org/A5078930847"],"corresponding_institution_ids":["https://openalex.org/I89630735"],"apc_list":{"value":2700,"currency":"CHF","value_usd":3258},"apc_paid":{"value":2700,"currency":"CHF","value_usd":3258},"fwci":0.4406,"has_fulltext":true,"cited_by_count":7,"citation_normalized_percentile":{"value":0.58105948,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":96},"biblio":{"volume":"19","issue":"9","first_page":"13990","last_page":"14003"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10602","display_name":"Glycosylation and Glycoproteins Research","score":0.9487000107765198,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10602","display_name":"Glycosylation and Glycoproteins Research","score":0.9487000107765198,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12477","display_name":"Toxin Mechanisms and Immunotoxins","score":0.014100000262260437,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12387","display_name":"Galectins and Cancer Biology","score":0.013799999840557575,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/galactose-specific-lectin","display_name":"galactose-specific lectin","score":0.9449999928474426},{"id":"https://openalex.org/keywords/aplysia-kurodai","display_name":"Aplysia kurodai","score":0.9340000152587891},{"id":"https://openalex.org/keywords/streptolysin-o","display_name":"streptolysin O","score":0.9829999804496765},{"id":"https://openalex.org/keywords/streptococcus-pyogenes","display_name":"Streptococcus pyogenes","score":0.925000011920929},{"id":"https://openalex.org/keywords/hemolysis-inhibition","display_name":"hemolysis inhibition","score":0.9620000123977661},{"id":"https://openalex.org/keywords/erythrocyte-membrane","display_name":"erythrocyte membrane","score":0.746999979019165},{"id":"https://openalex.org/keywords/glycosphingolipids","display_name":"glycosphingolipids","score":0.9890000224113464},{"id":"https://openalex.org/keywords/galactose","display_name":"galactose","score":0.7020000219345093},{"id":"https://openalex.org/keywords/lectin-glycan-interactions","display_name":"lectin-glycan interactions","score":0.421999990940094},{"id":"https://openalex.org/keywords/pore-formation","display_name":"pore formation","score":0.5559999942779541}],"concepts":[{"id":"https://openalex.org/C2776993315","wikidata":"https://www.wikidata.org/wiki/Q418187","display_name":"Streptolysin","level":4,"score":0.8913149237632751},{"id":"https://openalex.org/C2780758401","wikidata":"https://www.wikidata.org/wiki/Q408693","display_name":"Lectin","level":2,"score":0.7943270206451416},{"id":"https://openalex.org/C2779902561","wikidata":"https://www.wikidata.org/wiki/Q471706","display_name":"Hemolysis","level":2,"score":0.7940726280212402},{"id":"https://openalex.org/C2778173381","wikidata":"https://www.wikidata.org/wiki/Q66589593","display_name":"Galactose","level":2,"score":0.6398122906684875},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.6187127232551575},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5785776972770691},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.4328175485134125},{"id":"https://openalex.org/C2779719659","wikidata":"https://www.wikidata.org/wiki/Q24577942","display_name":"Mannan","level":3,"score":0.41423389315605164},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3363727927207947},{"id":"https://openalex.org/C100817775","wikidata":"https://www.wikidata.org/wiki/Q134219","display_name":"Polysaccharide","level":2,"score":0.14981502294540405},{"id":"https://openalex.org/C2993175405","wikidata":"https://www.wikidata.org/wiki/Q8054","display_name":"Bacterial protein","level":3,"score":0.0},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000900","descriptor_name":"Anti-Bacterial Agents","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D000900","descriptor_name":"Anti-Bacterial Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D000900","descriptor_name":"Anti-Bacterial Agents","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D001048","descriptor_name":"Aplysia","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D001426","descriptor_name":"Bacterial Proteins","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D004912","descriptor_name":"Erythrocytes","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D004912","descriptor_name":"Erythrocytes","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D006461","descriptor_name":"Hemolysis","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D008826","descriptor_name":"Microbial Sensitivity Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010063","descriptor_name":"Ovum","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D011817","descriptor_name":"Rabbits","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013297","descriptor_name":"Streptococcus pyogenes","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D013301","descriptor_name":"Streptolysins","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D037161","descriptor_name":"Galectins","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D037161","descriptor_name":"Galectins","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D037161","descriptor_name":"Galectins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D053878","descriptor_name":"Hemolytic Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false}],"locations_count":6,"locations":[{"id":"doi:10.3390/molecules190913990","doi":"https://doi.org/10.3390/molecules190913990","is_oa":true,"landing_page_url":"https://doi.org/10.3390/molecules190913990","pdf_url":"https://www.mdpi.com/1420-3049/19/9/13990/pdf?version=1453472702","source":{"id":"https://openalex.org/S108911230","display_name":"Molecules","issn_l":"1420-3049","issn":["1420-3049","1433-1373"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","medline","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecules","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:5276067","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6271371","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:6271371","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6271371","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecules","raw_type":"Text"},{"id":"pmid:25197935","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25197935","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecules (Basel, Switzerland)","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:9c02d8e22fe34b2e891c95b60927b3d4","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/9c02d8e22fe34b2e891c95b60927b3d4","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Molecules, Vol 19, Iss 9, Pp 13990-14003 (2014)","raw_type":"article"},{"id":"mag:3164531507","doi":null,"is_oa":false,"landing_page_url":"https://jglobal.jst.go.jp/detail?JGLOBAL_ID=201402205396406392","pdf_url":null,"source":{"id":"https://openalex.org/S4306520156","display_name":"Molecules (Web)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Molecules (Web)","raw_type":null}],"best_oa_location":{"id":"doi:10.3390/molecules190913990","doi":"https://doi.org/10.3390/molecules190913990","is_oa":true,"landing_page_url":"https://doi.org/10.3390/molecules190913990","pdf_url":"https://www.mdpi.com/1420-3049/19/9/13990/pdf?version=1453472702","source":{"id":"https://openalex.org/S108911230","display_name":"Molecules","issn_l":"1420-3049","issn":["1420-3049","1433-1373"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","medline","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecules","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.4043000042438507,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1062477961","display_name":"Structure and function of MytiLec-1, an alpha-galactose-binding lectin from the mussel Mytilus galloprovincialis.","funder_award_id":"25450306","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"},{"id":"https://openalex.org/G2983407875","display_name":"The Chromatoidmics analysis for clarification of spermatogenesis process","funder_award_id":"25840119","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"}],"funders":[{"id":"https://openalex.org/F4320334764","display_name":"Japan Society for the Promotion of Science","ror":"https://ror.org/00hhkn466"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2103649226.pdf","grobid_xml":"https://content.openalex.org/works/W2103649226.grobid-xml"},"referenced_works_count":38,"referenced_works":["https://openalex.org/W1501761217","https://openalex.org/W1502715236","https://openalex.org/W1528612603","https://openalex.org/W1784927340","https://openalex.org/W1974907979","https://openalex.org/W1988652789","https://openalex.org/W1993687533","https://openalex.org/W1998416098","https://openalex.org/W1998910316","https://openalex.org/W2007364271","https://openalex.org/W2017103071","https://openalex.org/W2022317687","https://openalex.org/W2022391141","https://openalex.org/W2024174950","https://openalex.org/W2027002447","https://openalex.org/W2028336439","https://openalex.org/W2035056901","https://openalex.org/W2047339233","https://openalex.org/W2053322952","https://openalex.org/W2058922550","https://openalex.org/W2059341891","https://openalex.org/W2060888441","https://openalex.org/W2063968553","https://openalex.org/W2072027767","https://openalex.org/W2077739032","https://openalex.org/W2086972154","https://openalex.org/W2088282707","https://openalex.org/W2095089677","https://openalex.org/W2096033318","https://openalex.org/W2100837269","https://openalex.org/W2132736439","https://openalex.org/W2144421472","https://openalex.org/W2163046411","https://openalex.org/W2171677744","https://openalex.org/W2218256551","https://openalex.org/W2315532268","https://openalex.org/W2399205461","https://openalex.org/W4232534952"],"related_works":["https://openalex.org/W2007364271","https://openalex.org/W1993687533","https://openalex.org/W3178821274","https://openalex.org/W2136134064","https://openalex.org/W1612331985","https://openalex.org/W2011426190","https://openalex.org/W2415180213","https://openalex.org/W2620693128","https://openalex.org/W7099838185","https://openalex.org/W3017389559"],"abstract_inverted_index":{"A":[0,78],"specific":[1],"galactose-binding":[2],"lectin":[3,52,99,140],"was":[4,47,67,121,135],"shown":[5],"to":[6,76],"inhibit":[7],"the":[8,70,91,102,115,155,161,176],"hemolytic":[9],"effect":[10,39,66],"of":[11,72,114,118,152,163,170,173],"streptolysin":[12],"O":[13],"(SLO),":[14],"an":[15],"exotoxin":[16],"produced":[17],"by":[18,49,69,96,123,137,150],"Streptococcus":[19],"pyogenes.":[20],"Commercially":[21],"available":[22],"lectins":[23,124,166],"that":[24,60,85,108],"recognize":[25],"N-acetyllactosamine":[26],"(ECA),":[27],"T-antigen":[28],"(PNA),":[29],"and":[30,106,130,145,165,180],"Tn-antigen":[31],"(ABA)":[32],"agglutinated":[33],"rabbit":[34],"erythrocytes,":[35],"but":[36,134],"had":[37],"no":[38],"on":[40],"SLO-induced":[41,45],"hemolysis.":[42],"In":[43],"contrast,":[44],"hemolysis":[46],"inhibited":[48,122],"AKL,":[50],"a":[51,126,131,138],"purified":[53],"from":[54,125],"sea":[55],"hare":[56],"(Aplysia":[57],"kurodai)":[58],"eggs":[59],"recognizes":[61],"\u03b1-galactoside":[62],"oligosaccharides.":[63],"This":[64],"inhibitory":[65,144],"blocked":[68,149],"co-presence":[71,151],"d-galactose,":[73],"which":[74],"binds":[75],"AKL.":[77],"possible":[79],"explanation":[80],"for":[81],"these":[82,143],"findings":[83,159],"is":[84],"cholesterol-enriched":[86],"microdomains":[87],"containing":[88],"glycosphingolipids":[89],"in":[90,112,154,167,175],"erythrocyte":[92],"membrane":[93],"become":[94],"occupied":[95],"tightly":[97],"stacked":[98],"molecules,":[100],"blocking":[101],"interaction":[103],"between":[104],"cholesterol":[105],"SLO":[107],"would":[109],"otherwise":[110],"result":[111],"penetration":[113],"membrane.":[116],"Growth":[117],"S.":[119],"pyogenes":[120],"marine":[127],"invertebrate":[128],"(AKL)":[129],"mushroom":[132],"(ABA),":[133],"promoted":[136],"plant":[139],"(ECA).":[141],"Both":[142],"promoting":[146],"effects":[147],"were":[148],"galactose":[153],"culture":[156],"medium.":[157],"Our":[158],"demonstrate":[160],"importance":[162],"glycans":[164],"regulating":[168],"mechanisms":[169],"toxicity,":[171],"creation":[172],"pores":[174],"target":[177],"cell":[178],"membrane,":[179],"bacterial":[181],"growth.":[182]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}