{"id":"https://openalex.org/W2103462792","doi":null,"title":"Evaluation of exogenous melatonin administration in improvement of sleep quality in patients with chronic obstructive pulmonary disease.","display_name":"Evaluation of exogenous melatonin administration in improvement of sleep quality in patients with chronic obstructive pulmonary disease.","publication_year":2013,"publication_date":"2013-01-01","ids":{"openalex":"https://openalex.org/W2103462792","mag":"2103462792","pmid":"https://pubmed.ncbi.nlm.nih.gov/25191456","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4153247"},"language":"en","primary_location":{"id":"pmh:oai:pubmedcentral.nih.gov:4153247","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC4153247/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC4153247/pdf/","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Tanaffos","raw_type":"Text"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC4153247/pdf/","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111908561","display_name":"Abolhasan Halvani","orcid":"https://orcid.org/0000-0002-4501-5535","observed_orcids":["https://orcid.org/0000-0002-4501-5535"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Abolhasan Halvani","raw_affiliation_strings":["Department of Internal Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048361298","display_name":"Fatemeh Mohsenpour","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Fatemeh Mohsenpour","raw_affiliation_strings":["Department of Internal Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5014567809","display_name":"Khadijeh Nasiriani","orcid":"https://orcid.org/0000-0003-3600-9456","observed_orcids":["https://orcid.org/0000-0003-3600-9456"]},"institutions":[{"id":"https://openalex.org/I223669574","display_name":"Shahid Sadoughi University of Medical Sciences and Health Services","ror":"https://ror.org/01zby9g91","country_code":"IR","type":"education","lineage":["https://openalex.org/I223669574"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Khadijeh Nasiriani","raw_affiliation_strings":["Nursing Department, Nursing & Midwifery School, Shahid Sadoughi University of Medical Sciences, YAZD-IRAN"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Nursing Department, Nursing & Midwifery School, Shahid Sadoughi University of Medical Sciences, YAZD-IRAN","institution_ids":["https://openalex.org/I223669574"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.1341,"has_fulltext":true,"cited_by_count":13,"citation_normalized_percentile":{"value":0.44938414,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"12","issue":"2","first_page":"9","last_page":"15"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10342","display_name":"Circadian rhythm and melatonin","score":0.6904000043869019,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10342","display_name":"Circadian rhythm and melatonin","score":0.6904000043869019,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10316","display_name":"Sleep and related disorders","score":0.22010000050067902,"subfield":{"id":"https://openalex.org/subfields/3205","display_name":"Experimental and Cognitive Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T10143","display_name":"Chronic Obstructive Pulmonary Disease (COPD) Research","score":0.05570000037550926,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/melatonin","display_name":"melatonin","score":0.9679999947547913},{"id":"https://openalex.org/keywords/chronic-obstructive-pulmonary-disease","display_name":"chronic obstructive pulmonary disease","score":0.9940000176429749},{"id":"https://openalex.org/keywords/sleep-quality","display_name":"sleep quality","score":1.0},{"id":"https://openalex.org/keywords/sleep-disturbance","display_name":"sleep disorders","score":0.9179999828338623},{"id":"https://openalex.org/keywords/daytime-sleepiness","display_name":"daytime sleepiness","score":0.8759999871253967},{"id":"https://openalex.org/keywords/sleep-onset-latency","display_name":"sleep latency","score":0.7289999723434448},{"id":"https://openalex.org/keywords/sleep-duration","display_name":"sleep duration","score":0.6740000247955322},{"id":"https://openalex.org/keywords/lung-function","display_name":"lung function","score":0.7440000176429749},{"id":"https://openalex.org/keywords/oxygenation","display_name":"oxygenation","score":0.8550000190734863},{"id":"https://openalex.org/keywords/sedative-hypnotics","display_name":"sedative-hypnotic drugs","score":0.7390000224113464}],"concepts":[{"id":"https://openalex.org/C2776245837","wikidata":"https://www.wikidata.org/wiki/Q25053505","display_name":"Pittsburgh Sleep Quality Index","level":4,"score":0.8578369617462158},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8428994417190552},{"id":"https://openalex.org/C2778664715","wikidata":"https://www.wikidata.org/wiki/Q1347756","display_name":"Epworth Sleepiness Scale","level":4,"score":0.8215950727462769},{"id":"https://openalex.org/C2778182776","wikidata":"https://www.wikidata.org/wiki/Q180912","display_name":"Melatonin","level":2,"score":0.7416548728942871},{"id":"https://openalex.org/C2776780178","wikidata":"https://www.wikidata.org/wiki/Q199804","display_name":"COPD","level":2,"score":0.6596944332122803},{"id":"https://openalex.org/C27081682","wikidata":"https://www.wikidata.org/wiki/Q269829","display_name":"Placebo","level":3,"score":0.6287569403648376},{"id":"https://openalex.org/C2780333948","wikidata":"https://www.wikidata.org/wiki/Q653305","display_name":"Spirometry","level":3,"score":0.6051363348960876},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4232482612133026},{"id":"https://openalex.org/C2781433485","wikidata":"https://www.wikidata.org/wiki/Q3144201","display_name":"Excessive daytime sleepiness","level":4,"score":0.4109165072441101},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.3870939612388611},{"id":"https://openalex.org/C1862650","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Physical therapy","level":1,"score":0.34127458930015564},{"id":"https://openalex.org/C1513209611","wikidata":"https://www.wikidata.org/wiki/Q177190","display_name":"Sleep disorder","level":3,"score":0.3362484872341156},{"id":"https://openalex.org/C2983189541","wikidata":"https://www.wikidata.org/wiki/Q35831","display_name":"Sleep quality","level":3,"score":0.2367183268070221},{"id":"https://openalex.org/C2778205975","wikidata":"https://www.wikidata.org/wiki/Q1754874","display_name":"Polysomnography","level":3,"score":0.2173106074333191},{"id":"https://openalex.org/C2781210498","wikidata":"https://www.wikidata.org/wiki/Q1869874","display_name":"Insomnia","level":2,"score":0.14850583672523499},{"id":"https://openalex.org/C2776042228","wikidata":"https://www.wikidata.org/wiki/Q35869","display_name":"Asthma","level":2,"score":0.11429452896118164},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.09808319807052612},{"id":"https://openalex.org/C2781326671","wikidata":"https://www.wikidata.org/wiki/Q754424","display_name":"Apnea","level":2,"score":0.05498799681663513},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0}],"mesh":[],"locations_count":5,"locations":[{"id":"pmh:oai:pubmedcentral.nih.gov:4153247","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC4153247/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC4153247/pdf/","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Tanaffos","raw_type":"Text"},{"id":"pmh:oai:europepmc.org:3124250","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4153247","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmid:25191456","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25191456","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Tanaffos","raw_type":"Journal Article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.801.2702","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.801.2702","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/77/53/Tanaffos-12-009.PMC4153247.pdf","raw_type":"text"},{"id":"mag:2103462792","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25191456","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:4153247","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC4153247/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC4153247/pdf/","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Tanaffos","raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[{"display_name":"Randomized Controlled Trial","id":"https://openalex.org/study-designs/randomized-controlled-trial"},{"display_name":"Clinical Trial","id":"https://openalex.org/study-designs/clinical-trial"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2103462792.pdf","grobid_xml":"https://content.openalex.org/works/W2103462792.grobid-xml"},"referenced_works_count":41,"referenced_works":["https://openalex.org/W47750904","https://openalex.org/W119823048","https://openalex.org/W197066864","https://openalex.org/W198995741","https://openalex.org/W1973655938","https://openalex.org/W1974254409","https://openalex.org/W1976584787","https://openalex.org/W1977021680","https://openalex.org/W1981681632","https://openalex.org/W1983678314","https://openalex.org/W1990412036","https://openalex.org/W1998459991","https://openalex.org/W2010096739","https://openalex.org/W2026484597","https://openalex.org/W2026499681","https://openalex.org/W2028067503","https://openalex.org/W2034551798","https://openalex.org/W2055803040","https://openalex.org/W2063366774","https://openalex.org/W2071370712","https://openalex.org/W2079798208","https://openalex.org/W2081789625","https://openalex.org/W2085626908","https://openalex.org/W2091522006","https://openalex.org/W2093200944","https://openalex.org/W2097252156","https://openalex.org/W2098253552","https://openalex.org/W2104168490","https://openalex.org/W2107183424","https://openalex.org/W2113558571","https://openalex.org/W2116784557","https://openalex.org/W2120007669","https://openalex.org/W2126354773","https://openalex.org/W2127363001","https://openalex.org/W2127951128","https://openalex.org/W2135777766","https://openalex.org/W2145234674","https://openalex.org/W2151487996","https://openalex.org/W2152463727","https://openalex.org/W2161243447","https://openalex.org/W2164732757"],"related_works":["https://openalex.org/W2063366774","https://openalex.org/W7017921171","https://openalex.org/W2103381589","https://openalex.org/W2344568578","https://openalex.org/W2626112180","https://openalex.org/W2091819035","https://openalex.org/W7039047636","https://openalex.org/W2899485526","https://openalex.org/W1586791826","https://openalex.org/W2171308617"],"abstract_inverted_index":{"BACKGROUND:":[0],"COPD":[1,34,83,202],"is":[2,30,48],"primarily":[3],"the":[4,7,40,72,177,211,217],"disease":[5],"of":[6,27,74,79,97,187,213,219],"lungs;":[8],"nevertheless,":[9],"multiple":[10],"systemic":[11],"manifestations":[12],"including":[13],"poor":[14],"sleep":[15,18,59,80,161,164,167,171,199,205],"quality":[16,81,112,162,200],"and":[17,43,64,102,134,143,170,192,222],"disturbances":[19,60],"have":[20],"been":[21,54],"linked":[22],"to":[23,57,70,139],"this":[24],"illness.":[25],"Administration":[26],"sedative":[28],"hypnotics":[29],"not":[31,183],"recommended":[32],"in":[33,77,82,201,210,216],"patients,":[35,132],"as":[36],"these":[37],"drugs":[38],"suppress":[39],"ventilatory":[41],"response":[42],"exacerbate":[44],"sleep-related":[45],"disorders.":[46],"Melatonin":[47,196],"an":[49],"alternative":[50],"medication":[51],"that":[52],"has":[53],"widely":[55],"used":[56],"treat":[58],"caused":[61],"by":[62,115,125],"aging":[63],"other":[65,178],"specific":[66],"conditions.":[67],"We":[68],"aimed":[69],"investigate":[71],"efficacy":[73,168],"melatonin":[75,107,149,180],"administration":[76,150],"improvement":[78,208],"patients.":[84],"MATERIALS":[85],"AND":[86],"METHODS:":[87],"A":[88,95],"randomized,":[89],"double-blind,":[90],"placebo-controlled":[91],"trial":[92],"was":[93,113,123,209],"conducted.":[94],"total":[96],"54":[98],"patients":[99,203],"were":[100,137],"recruited":[101],"randomly":[103],"assigned":[104],"into":[105],"either":[106],"or":[108],"placebo":[109],"group.":[110],"Sleep":[111,117],"evaluated":[114],"Pittsburgh":[116],"Quality":[118],"Index":[119],"(PSQI);":[120],"daytime":[121,188,220],"sleepiness":[122,221],"assessed":[124],"Epworth":[126],"Sleepiness":[127],"Scale":[128],"(ESS).":[129],"For":[130],"all":[131],"spirometry":[133],"pulse":[135],"oximetry":[136],"preformed":[138],"evaluate":[140],"lung":[141,190,223],"function":[142,191],"oxygenation.":[144],"RESULTS:":[145],"Compared":[146],"with":[147,204],"placebo,":[148],"significantly":[151,184,197],"improved":[152,174],"global":[153],"PSQI":[154,158],"score":[155],"(p<0.001).":[156],"Of":[157],"individual":[159],"components,":[160],"(p=0.001),":[163,166],"latency":[165],"(p=0.003),":[169],"duration":[172],"(p=0.024)":[173],"significantly.":[175],"On":[176],"hand,":[179],"treatment":[181],"did":[182],"change":[185],"indices":[186,218],"sleepiness,":[189],"oxygenation":[193],"(p>0.05).":[194],"CONCLUSION:":[195],"improves":[198],"complaints.":[206],"This":[207],"absence":[212],"significant":[214],"elevation":[215],"function.":[224]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2021,"cited_by_count":4},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":3},{"year":2015,"cited_by_count":1}],"updated_date":"2026-11-11T12:16:26.678958","created_date":"2016-06-24T00:00:00"}