{"id":"https://openalex.org/W2103435633","doi":"https://doi.org/10.1046/j.1365-2362.2000.00623.x","title":"Encapsulated fish oil enriched in \u03b1\u2010tocopherol alters plasma phospholipid and mononuclear cell fatty acid compositions but not mononuclear cell functions","display_name":"Encapsulated fish oil enriched in \u03b1\u2010tocopherol alters plasma phospholipid and mononuclear cell fatty acid compositions but not mononuclear cell functions","publication_year":2000,"publication_date":"2000-03-01","ids":{"openalex":"https://openalex.org/W2103435633","doi":"https://doi.org/10.1046/j.1365-2362.2000.00623.x","mag":"2103435633","pmid":"https://pubmed.ncbi.nlm.nih.gov/10692004"},"language":"en","primary_location":{"id":"doi:10.1046/j.1365-2362.2000.00623.x","doi":"https://doi.org/10.1046/j.1365-2362.2000.00623.x","is_oa":false,"landing_page_url":"https://doi.org/10.1046/j.1365-2362.2000.00623.x","pdf_url":null,"source":{"id":"https://openalex.org/S153084679","display_name":"European Journal of Clinical Investigation","issn_l":"0014-2972","issn":["0014-2972","1365-2362"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Journal of Clinical Investigation","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5015403105","display_name":"Yaqoob Yaqoob","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Yaqoob","raw_affiliation_strings":["University of Oxford, Oxford, UK","Department of Biochemistry ,  University of Oxford ,  Oxford ,  UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Oxford, Oxford, UK","institution_ids":["https://openalex.org/I40120149"]},{"raw_affiliation_string":"Department of Biochemistry ,  University of Oxford ,  Oxford ,  UK","institution_ids":["https://openalex.org/I40120149"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Pala","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Pala","raw_affiliation_strings":["University of Oxford, Oxford, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Oxford, Oxford, UK","institution_ids":["https://openalex.org/I40120149"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090704136","display_name":"Mario Cortina\u2010Borja","orcid":"https://orcid.org/0000-0003-0627-2624","observed_orcids":["https://orcid.org/0000-0003-0627-2624"]},"institutions":[{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Cortina\u2010Borja","raw_affiliation_strings":["University of Oxford, Oxford, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Oxford, Oxford, UK","institution_ids":["https://openalex.org/I40120149"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5098225615","display_name":"Newsholme","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Newsholme","raw_affiliation_strings":["University of Oxford, Oxford, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Oxford, Oxford, UK","institution_ids":["https://openalex.org/I40120149"]}]},{"author_position":"last","author":{"id":null,"display_name":"Calder","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Calder","raw_affiliation_strings":["University of Oxford, Oxford, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Oxford, Oxford, UK","institution_ids":["https://openalex.org/I40120149"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I40120149"],"apc_list":{"value":4100,"currency":"USD","value_usd":4100},"apc_paid":null,"fwci":10.488,"has_fulltext":false,"cited_by_count":308,"citation_normalized_percentile":{"value":0.98633581,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":98,"max":100},"biblio":{"volume":"30","issue":"3","first_page":"260","last_page":"274"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10387","display_name":"Fatty Acid Research and Health","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10387","display_name":"Fatty Acid Research and Health","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10909","display_name":"Edible Oils Quality and Analysis","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10450","display_name":"Aquaculture Nutrition and Growth","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1104","display_name":"Aquatic Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/fish-oil-supplementation","display_name":"fish oil supplementation","score":0.9419999718666077},{"id":"https://openalex.org/keywords/alpha-tocopherol","display_name":"alpha-tocopherol","score":0.906000018119812},{"id":"https://openalex.org/keywords/omega-3-fatty-acids","display_name":"omega-3 fatty acids","score":0.7760000228881836},{"id":"https://openalex.org/keywords/eicosapentaenoic-acid","display_name":"eicosapentaenoic acid","score":0.9670000076293945},{"id":"https://openalex.org/keywords/docosahexaenoic-acid","display_name":"docosahexaenoic acid","score":1.0},{"id":"https://openalex.org/keywords/plasma-phospholipids","display_name":"plasma phospholipids","score":0.890999972820282},{"id":"https://openalex.org/keywords/peripheral-blood-mononuclear-cells","display_name":"peripheral blood mononuclear cells","score":0.9390000104904175},{"id":"https://openalex.org/keywords/dihomo-gamma-linolenic-acid","display_name":"dihomo-gamma-linolenic acid","score":0.8920000195503235},{"id":"https://openalex.org/keywords/evening-primrose-oil","display_name":"evening primrose oil","score":0.8500000238418579},{"id":"https://openalex.org/keywords/olive-oil","display_name":"olive oil","score":0.6209999918937683},{"id":"https://openalex.org/keywords/safflower-oil","display_name":"safflower oil","score":0.9509999752044678},{"id":"https://openalex.org/keywords/coconut-oil","display_name":"coconut oil","score":0.5299999713897705},{"id":"https://openalex.org/keywords/arachidonic-acid","display_name":"arachidonic acid","score":0.7409999966621399},{"id":"https://openalex.org/keywords/lipid-peroxidation","display_name":"lipid peroxidation","score":0.7549999952316284},{"id":"https://openalex.org/keywords/antioxidant-capacity","display_name":"antioxidant capacity","score":0.7630000114440918},{"id":"https://openalex.org/keywords/lymphocyte-proliferation","display_name":"lymphocyte proliferation","score":0.7179999947547913},{"id":"https://openalex.org/keywords/nk-cell-cytotoxicity","display_name":"NK cell cytotoxicity","score":0.9079999923706055},{"id":"https://openalex.org/keywords/cytokine-production","display_name":"cytokine production","score":0.9470000267028809}],"concepts":[{"id":"https://openalex.org/C2779946292","wikidata":"https://www.wikidata.org/wiki/Q1786125","display_name":"Fish oil","level":3,"score":0.7896016836166382},{"id":"https://openalex.org/C137061746","wikidata":"https://www.wikidata.org/wiki/Q736033","display_name":"Peripheral blood mononuclear cell","level":3,"score":0.7122921943664551},{"id":"https://openalex.org/C2776091944","wikidata":"https://www.wikidata.org/wiki/Q409990","display_name":"Eicosapentaenoic acid","level":4,"score":0.6792813539505005},{"id":"https://openalex.org/C2910491948","wikidata":"https://www.wikidata.org/wiki/Q157353","display_name":"Evening Primrose Oil","level":2,"score":0.6133697628974915},{"id":"https://openalex.org/C2777171753","wikidata":"https://www.wikidata.org/wiki/Q423345","display_name":"Docosahexaenoic acid","level":4,"score":0.5845303535461426},{"id":"https://openalex.org/C2778717857","wikidata":"https://www.wikidata.org/wiki/Q818405","display_name":"Linseed oil","level":2,"score":0.53690505027771},{"id":"https://openalex.org/C19038510","wikidata":"https://www.wikidata.org/wiki/Q2005087","display_name":"Polyunsaturated fatty acid","level":3,"score":0.5351788401603699},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.49369725584983826},{"id":"https://openalex.org/C543025807","wikidata":"https://www.wikidata.org/wiki/Q61476","display_name":"Fatty acid","level":2,"score":0.4458777606487274},{"id":"https://openalex.org/C2778918659","wikidata":"https://www.wikidata.org/wiki/Q186915","display_name":"Phospholipid","level":3,"score":0.44028782844543457},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.42369532585144043},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.413951575756073},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.40625178813934326},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.3504309356212616},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.33317792415618896},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3186464309692383},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.24752157926559448},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.06865909695625305},{"id":"https://openalex.org/C505870484","wikidata":"https://www.wikidata.org/wiki/Q180538","display_name":"Fishery","level":1,"score":0.0},{"id":"https://openalex.org/C41625074","wikidata":"https://www.wikidata.org/wiki/Q176088","display_name":"Membrane","level":2,"score":0.0},{"id":"https://openalex.org/C2909208804","wikidata":"https://www.wikidata.org/wiki/Q127282","display_name":"Fish <Actinopterygii>","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003601","descriptor_name":"Cytotoxicity Tests, Immunologic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004311","descriptor_name":"Double-Blind Method","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005227","descriptor_name":"Fatty Acids","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007963","descriptor_name":"Leukocytes, Mononuclear","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D007963","descriptor_name":"Leukocytes, Mononuclear","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D008213","descriptor_name":"Lymphocyte Activation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010084","descriptor_name":"Oxidation-Reduction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010743","descriptor_name":"Phospholipids","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D010938","descriptor_name":"Plant Oils","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D014810","descriptor_name":"Vitamin E","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D014810","descriptor_name":"Vitamin E","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D014810","descriptor_name":"Vitamin E","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D015525","descriptor_name":"Fatty Acids, Omega-3","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D015525","descriptor_name":"Fatty Acids, Omega-3","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D015525","descriptor_name":"Fatty Acids, Omega-3","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D016130","descriptor_name":"Immunophenotyping","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016207","descriptor_name":"Cytokines","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D017392","descriptor_name":"Thiobarbituric Acid Reactive Substances","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D019587","descriptor_name":"Dietary Supplements","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1046/j.1365-2362.2000.00623.x","doi":"https://doi.org/10.1046/j.1365-2362.2000.00623.x","is_oa":false,"landing_page_url":"https://doi.org/10.1046/j.1365-2362.2000.00623.x","pdf_url":null,"source":{"id":"https://openalex.org/S153084679","display_name":"European Journal of Clinical Investigation","issn_l":"0014-2972","issn":["0014-2972","1365-2362"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Journal of Clinical Investigation","raw_type":"journal-article"},{"id":"pmid:10692004","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10692004","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European journal of clinical investigation","raw_type":"Clinical Trial"},{"id":"pmh:oai:eprints.ucl.ac.uk.OAI2:117454","doi":null,"is_oa":false,"landing_page_url":"http://discovery.ucl.ac.uk/117454/","pdf_url":null,"source":{"id":"https://openalex.org/S4306400024","display_name":"UCL Discovery (University College London)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I45129253","host_organization_name":"University College London","host_organization_lineage":["https://openalex.org/I45129253"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"EUR J CLIN INVEST , 30 (3) 260 - 274. (2000)","raw_type":"Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":53,"referenced_works":["https://openalex.org/W73392286","https://openalex.org/W202247763","https://openalex.org/W292936021","https://openalex.org/W1524195188","https://openalex.org/W1644110135","https://openalex.org/W1904905341","https://openalex.org/W1905885236","https://openalex.org/W1907408924","https://openalex.org/W1908735180","https://openalex.org/W1924401820","https://openalex.org/W1933365559","https://openalex.org/W1961179371","https://openalex.org/W1970213952","https://openalex.org/W1974834425","https://openalex.org/W1989435086","https://openalex.org/W1995822311","https://openalex.org/W2004515700","https://openalex.org/W2005722435","https://openalex.org/W2007001167","https://openalex.org/W2013751321","https://openalex.org/W2035374971","https://openalex.org/W2040294075","https://openalex.org/W2042455028","https://openalex.org/W2042672223","https://openalex.org/W2045910289","https://openalex.org/W2046105674","https://openalex.org/W2049500405","https://openalex.org/W2052302005","https://openalex.org/W2056382301","https://openalex.org/W2061382445","https://openalex.org/W2075943582","https://openalex.org/W2076623706","https://openalex.org/W2083219554","https://openalex.org/W2089132590","https://openalex.org/W2101541068","https://openalex.org/W2104625208","https://openalex.org/W2119345102","https://openalex.org/W2119624564","https://openalex.org/W2121048724","https://openalex.org/W2128064203","https://openalex.org/W2134749506","https://openalex.org/W2138577332","https://openalex.org/W2145221481","https://openalex.org/W2145649490","https://openalex.org/W2151211184","https://openalex.org/W2183334271","https://openalex.org/W2287666202","https://openalex.org/W2322802533","https://openalex.org/W2327515496","https://openalex.org/W2339328874","https://openalex.org/W2401563392","https://openalex.org/W2407639795","https://openalex.org/W4239459448"],"related_works":["https://openalex.org/W1976536546","https://openalex.org/W2082335253","https://openalex.org/W2097196982","https://openalex.org/W2030954437","https://openalex.org/W2079115961","https://openalex.org/W2113579246","https://openalex.org/W2099187662","https://openalex.org/W1937525355","https://openalex.org/W1977669693","https://openalex.org/W7056055667"],"abstract_inverted_index":{"BACKGROUND:":[0],"Several":[1],"studies":[2,28],"have":[3,29,35],"reported":[4],"that":[5],"dietary":[6],"fish":[7],"oil":[8,62,73,76,80],"(FO)":[9],"supplementation":[10,310,328],"alters":[11,414],"cytokine":[12,166],"production":[13,380],"and":[14,33,69,116,118,123,130,155,157,185,213,252,281,283,297,314,417],"other":[15],"functional":[16,38],"activities":[17],"of":[18,26,59,67,141,147,178,201,224,245,255,267,276,291,304,327,331,348,355,368,381,384,402,424,426,436],"peripheral":[19],"blood":[20,371,388],"mononuclear":[21],"cells":[22],"(PBMC).":[23],"However,":[24],"few":[25,34],"these":[27],"been":[30],"placebo":[31,61],"controlled":[32],"related":[36],"the":[37,101,139,145,150,228,243,248,274,289,320,332,346,353,366,377,403,434,440],"changes":[39],"to":[40,316,433],"alterations":[41],"in":[42,204,209,216,227,233,242,247,273,278,288,294,311,439],"PBMC":[43,119,124,143,148,158,195,232,253,350,356,391,418,429],"fatty":[44,125,196,419],"acid":[45,88,94,126,197,203,226,293,420],"composition":[46],"PATIENTS":[47],"AND":[48],"METHODS:":[49],"Healthy":[50],"subjects":[51,210,217,234,256,313],"supplemented":[52],"their":[53],"diets":[54],"with":[55,329,405],"9":[56],"g":[57,86,92,407],"day-1":[58],"encapsulated":[60],"(3":[63],":":[64],"1":[65],"mix":[66],"coconut":[68],"soybean":[70],"oils),":[71],"olive":[72],"(OO),":[74],"safflower":[75],"(SO),":[77],"evening":[78],"primrose":[79],"(EPO)":[81],"or":[82,194,231,339,344,373,375,390,398],"FO":[83,258,300,427],"[providing":[84],"2.1":[85],"eicosapentaenoic":[87],"(EPA)":[89],"plus":[90,409],"1.1":[91],"docosahexaenoic":[93],"(DHA)":[95],"per":[96,108,411],"day]":[97],"for":[98],"12":[99],"weeks;":[100],"capsules":[102,187,333],"also":[103],"provided":[104],"205":[105],"mg":[106],"alpha-tocopherol":[107,129,305,437],"day.":[109],"Blood":[110],"was":[111,207,214,221,238,262,270],"sampled":[112],"at":[113],"4-weekly":[114],"intervals":[115],"plasma":[117,128,135,192,205,229,249,279,295,336,340,415],"prepared.":[120],"Plasma":[121,302],"phospholipid":[122,193,416],"composition,":[127],"thiobarbituric":[131,341],"acid-reactive":[132,342],"substance":[133],"concentrations,":[134],"total":[136,335],"antioxidant":[137,337],"capacity,":[138],"proportions":[140,146],"different":[142,349],"subsets,":[144,351],"expressing":[149,357],"adhesion":[151,358],"molecules":[152],"CD2,":[153],"CD11b":[154],"CD54,":[156],"functions":[159,430],"(lymphocyte":[160],"proliferation,":[161],"natural":[162,361],"killer":[163,362],"cell":[164,363],"activity,":[165,364],"production)":[167],"were":[168,172,306,324],"measured.":[169],"All":[170],"measurements":[171],"repeated":[173],"after":[174,264,319],"a":[175,239,382],"'washout'":[176],"period":[177],"8":[179],"weeks.":[180],"RESULTS:":[181],"The":[182,199,422],"placebo,":[183],"OO":[184],"SO":[186],"had":[188],"no":[189,222,325],"effect":[190,425],"on":[191,334,345,352,360,365,376],"composition.":[198],"proportion":[200,244,275,290,347,354],"dihomo-gamma-linolenic":[202],"phospholipids":[206,230,250,280,296],"elevated":[208,308],"taking":[211,218,235,257],"EPO":[212],"decreased":[215],"FO.":[219],"There":[220,237,269,323],"appearance":[223],"gamma-linolenic":[225],"EPO.":[236],"marked":[240],"increase":[241,261,272],"EPA":[246,408],"(10-fold)":[251],"(four-fold)":[254],"supplements;":[259],"this":[260],"maximal":[263],"4":[265],"weeks":[266],"supplementation.":[268,301],"an":[271,284],"DHA":[277,410],"PBMC,":[282,298,374],"approximately":[285],"20%":[286],"decrease":[287],"arachidonic":[292],"during":[299,309],"concentrations":[303],"significantly":[307],"all":[312],"returned":[315],"baseline":[317],"values":[318],"washout":[321],"period.":[322],"effects":[326],"any":[330],"activity":[338],"substances":[343],"molecules,":[359],"proliferation":[367],"mitogen-stimulated":[369],"whole":[370,387],"cultures":[372,389,392],"ex":[378],"vivo":[379],"range":[383],"cytokines":[385],"by":[386,394],"stimulated":[393],"either":[395],"concanavalin":[396],"A":[397],"lipopolysaccharide.":[399],"CONCLUSION:":[400],"Supplementation":[401],"diet":[404],"3.2":[406],"day":[412],"markedly":[413],"compositions.":[421],"lack":[423],"upon":[428],"may":[431],"relate":[432],"level":[435],"included":[438],"supplements.":[441]},"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":9},{"year":2023,"cited_by_count":9},{"year":2022,"cited_by_count":8},{"year":2021,"cited_by_count":11},{"year":2020,"cited_by_count":13},{"year":2019,"cited_by_count":13},{"year":2018,"cited_by_count":11},{"year":2017,"cited_by_count":11},{"year":2016,"cited_by_count":14},{"year":2015,"cited_by_count":7},{"year":2014,"cited_by_count":11},{"year":2013,"cited_by_count":15},{"year":2012,"cited_by_count":19}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}