{"id":"https://openalex.org/W2103418138","doi":"https://doi.org/10.1016/j.ejvs.2004.08.003","title":"Manipulation of the Renin Angiotensin System in Peripheral Arterial Disease","display_name":"Manipulation of the Renin Angiotensin System in Peripheral Arterial Disease","publication_year":2004,"publication_date":"2004-10-05","ids":{"openalex":"https://openalex.org/W2103418138","doi":"https://doi.org/10.1016/j.ejvs.2004.08.003","mag":"2103418138","pmid":"https://pubmed.ncbi.nlm.nih.gov/15531190"},"language":"en","primary_location":{"id":"doi:10.1016/j.ejvs.2004.08.003","doi":"https://doi.org/10.1016/j.ejvs.2004.08.003","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.ejvs.2004.08.003","pdf_url":"http://www.ejves.com/article/S1078588404003946/pdf","source":{"id":"https://openalex.org/S138569045","display_name":"European Journal of Vascular and Endovascular Surgery","issn_l":"1078-5884","issn":["1078-5884","1532-2165"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Journal of Vascular and Endovascular Surgery","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"http://www.ejves.com/article/S1078588404003946/pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5103483215","display_name":"S.D. Hobbs","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210104666","display_name":"Heartlands Hospital","ror":"https://ror.org/01bd5gh54","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4210104666"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"S.D. Hobbs","raw_affiliation_strings":["University Department of Vascular Surgery, Birmingham Heartlands and Solihull NHS Trust (Teaching), Birmingham, UK. simon@hobbsy.fsworld.co.uk","University Department of Vascular Surgery, Birmingham Heartlands and Solihull NHS Trust (Teaching), Birmingham, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University Department of Vascular Surgery, Birmingham Heartlands and Solihull NHS Trust (Teaching), Birmingham, UK. simon@hobbsy.fsworld.co.uk","institution_ids":["https://openalex.org/I4210104666"]},{"raw_affiliation_string":"University Department of Vascular Surgery, Birmingham Heartlands and Solihull NHS Trust (Teaching), Birmingham, UK","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"M.E. Thomas","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M.E. Thomas","raw_affiliation_strings":["Department of Nephrology, Birmingham Heartlands and Solihull NHS Trust (Teaching), Birmingham, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nephrology, Birmingham Heartlands and Solihull NHS Trust (Teaching), Birmingham, UK","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5027703697","display_name":"Andrew W. Bradbury","orcid":"https://orcid.org/0000-0003-0530-9667","observed_orcids":["https://orcid.org/0000-0003-0530-9667"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A.W. Bradbury","raw_affiliation_strings":["University Department of Vascular Surgery, Birmingham Heartlands and Solihull NHS Trust (Teaching), Birmingham, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University Department of Vascular Surgery, Birmingham Heartlands and Solihull NHS Trust (Teaching), Birmingham, UK","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5103483215"],"corresponding_institution_ids":["https://openalex.org/I4210104666"],"apc_list":{"value":4000,"currency":"USD","value_usd":4000},"apc_paid":null,"fwci":0.3469,"has_fulltext":true,"cited_by_count":17,"citation_normalized_percentile":{"value":0.39904306,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":"28","issue":"6","first_page":"573","last_page":"582"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11001","display_name":"Renin-Angiotensin System Studies","score":0.7348999977111816,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11001","display_name":"Renin-Angiotensin System Studies","score":0.7348999977111816,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10926","display_name":"Peripheral Artery Disease Management","score":0.20960000157356262,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12067","display_name":"Renal and Vascular Pathologies","score":0.039799999445676804,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/renin-angiotensin-system","display_name":"renin-angiotensin system","score":0.9729999899864197},{"id":"https://openalex.org/keywords/peripheral-arterial-disease","display_name":"peripheral arterial disease","score":0.9990000128746033},{"id":"https://openalex.org/keywords/ace-inhibitors","display_name":"ACE inhibitors","score":0.9929999709129333},{"id":"https://openalex.org/keywords/ramipril","display_name":"ramipril","score":0.9990000128746033},{"id":"https://openalex.org/keywords/renal-artery-stenosis","display_name":"renal artery stenosis","score":0.9850000143051147},{"id":"https://openalex.org/keywords/optimal-medical-therapy","display_name":"optimal medical therapy","score":0.8539999723434448},{"id":"https://openalex.org/keywords/pathophysiology","display_name":"pathophysiology","score":0.6330000162124634}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9423020482063293},{"id":"https://openalex.org/C198710026","wikidata":"https://www.wikidata.org/wiki/Q898218","display_name":"Renin\u2013angiotensin system","level":3,"score":0.7430899143218994},{"id":"https://openalex.org/C46762472","wikidata":"https://www.wikidata.org/wiki/Q178648","display_name":"Peripheral","level":2,"score":0.7141968607902527},{"id":"https://openalex.org/C3018348675","wikidata":"https://www.wikidata.org/wiki/Q4797557","display_name":"Arterial disease","level":3,"score":0.506862461566925},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4816981256008148},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.42323172092437744},{"id":"https://openalex.org/C2777466421","wikidata":"https://www.wikidata.org/wiki/Q1266890","display_name":"Vascular disease","level":2,"score":0.2407437562942505},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.19033348560333252}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000804","descriptor_name":"Angiotensin II","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D000806","descriptor_name":"Angiotensin-Converting Enzyme Inhibitors","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D000806","descriptor_name":"Angiotensin-Converting Enzyme Inhibitors","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012078","descriptor_name":"Renal Artery Obstruction","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D012078","descriptor_name":"Renal Artery Obstruction","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D012084","descriptor_name":"Renin-Angiotensin System","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D012084","descriptor_name":"Renin-Angiotensin System","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D015897","descriptor_name":"Comorbidity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016491","descriptor_name":"Peripheral Vascular Diseases","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D016491","descriptor_name":"Peripheral Vascular Diseases","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D016491","descriptor_name":"Peripheral Vascular Diseases","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D017257","descriptor_name":"Ramipril","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D057911","descriptor_name":"Angiotensin Receptor Antagonists","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1016/j.ejvs.2004.08.003","doi":"https://doi.org/10.1016/j.ejvs.2004.08.003","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.ejvs.2004.08.003","pdf_url":"http://www.ejves.com/article/S1078588404003946/pdf","source":{"id":"https://openalex.org/S138569045","display_name":"European Journal of Vascular and Endovascular Surgery","issn_l":"1078-5884","issn":["1078-5884","1532-2165"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Journal of Vascular and Endovascular Surgery","raw_type":"journal-article"},{"id":"pmid:15531190","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15531190","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery","raw_type":"Journal Article"},{"id":"pmh:oai:pure.atira.dk:openaire_cris_publications/9957fb4f-c33e-4ee7-8675-1de50e6f67aa","doi":null,"is_oa":false,"landing_page_url":"https://research.birmingham.ac.uk/en/publications/9957fb4f-c33e-4ee7-8675-1de50e6f67aa","pdf_url":null,"source":{"id":"https://openalex.org/S4306402634","display_name":"University of Birmingham Research Portal (University of Birmingham)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I79619799","host_organization_name":"University of Birmingham","host_organization_lineage":["https://openalex.org/I79619799"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Hobbs, S, Thomas, M & Bradbury, A 2004, 'Manipulation of the Renin Angiotensin System in Peripheral Arterial Disease', European Journal of Vascular and Endovascular Surgery, vol. 28, pp. 573-582. https://doi.org/10.1016/j.ejvs.2004.08.003","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1016/j.ejvs.2004.08.003","doi":"https://doi.org/10.1016/j.ejvs.2004.08.003","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.ejvs.2004.08.003","pdf_url":"http://www.ejves.com/article/S1078588404003946/pdf","source":{"id":"https://openalex.org/S138569045","display_name":"European Journal of Vascular and Endovascular Surgery","issn_l":"1078-5884","issn":["1078-5884","1532-2165"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Journal of Vascular and Endovascular Surgery","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2103418138.pdf","grobid_xml":"https://content.openalex.org/works/W2103418138.grobid-xml"},"referenced_works_count":64,"referenced_works":["https://openalex.org/W180946569","https://openalex.org/W200306471","https://openalex.org/W424467158","https://openalex.org/W1486580743","https://openalex.org/W1777105685","https://openalex.org/W1929271963","https://openalex.org/W1940380821","https://openalex.org/W1969673587","https://openalex.org/W1970400657","https://openalex.org/W1973596308","https://openalex.org/W1974994009","https://openalex.org/W1976346162","https://openalex.org/W1981721115","https://openalex.org/W1983150843","https://openalex.org/W1987512785","https://openalex.org/W1992029745","https://openalex.org/W2002339517","https://openalex.org/W2007242346","https://openalex.org/W2016046345","https://openalex.org/W2021011733","https://openalex.org/W2025028635","https://openalex.org/W2025970694","https://openalex.org/W2029353985","https://openalex.org/W2031478118","https://openalex.org/W2034914625","https://openalex.org/W2039665384","https://openalex.org/W2046524322","https://openalex.org/W2048161449","https://openalex.org/W2055864845","https://openalex.org/W2056720539","https://openalex.org/W2059091616","https://openalex.org/W2060473309","https://openalex.org/W2062868777","https://openalex.org/W2070763907","https://openalex.org/W2074256067","https://openalex.org/W2075569679","https://openalex.org/W2088405610","https://openalex.org/W2088745867","https://openalex.org/W2092314772","https://openalex.org/W2094727696","https://openalex.org/W2100082183","https://openalex.org/W2106468309","https://openalex.org/W2116631824","https://openalex.org/W2122052038","https://openalex.org/W2135038122","https://openalex.org/W2148688310","https://openalex.org/W2153615786","https://openalex.org/W2154360613","https://openalex.org/W2164072261","https://openalex.org/W2166469889","https://openalex.org/W2167590235","https://openalex.org/W2170226691","https://openalex.org/W2261619414","https://openalex.org/W2279396267","https://openalex.org/W2417638832","https://openalex.org/W2433692160","https://openalex.org/W2468151691","https://openalex.org/W2617392052","https://openalex.org/W2747176423","https://openalex.org/W2946929330","https://openalex.org/W4230893588","https://openalex.org/W4285719527","https://openalex.org/W4293085726","https://openalex.org/W7073887565"],"related_works":["https://openalex.org/W2585021310","https://openalex.org/W2043725216","https://openalex.org/W1976711710","https://openalex.org/W2411097333","https://openalex.org/W2410383841","https://openalex.org/W2053949268","https://openalex.org/W1984992817","https://openalex.org/W1974370899","https://openalex.org/W2029353985","https://openalex.org/W2232462823"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2024,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}