{"id":"https://openalex.org/W2103333652","doi":"https://doi.org/10.1016/j.neuroimage.2014.02.029","title":"Evidence that the negative BOLD response is neuronal in origin: A simultaneous EEG\u2013BOLD\u2013CBF study in humans","display_name":"Evidence that the negative BOLD response is neuronal in origin: A simultaneous EEG\u2013BOLD\u2013CBF study in humans","publication_year":2014,"publication_date":"2014-03-14","ids":{"openalex":"https://openalex.org/W2103333652","doi":"https://doi.org/10.1016/j.neuroimage.2014.02.029","mag":"2103333652","pmid":"https://pubmed.ncbi.nlm.nih.gov/24632092"},"language":"en","primary_location":{"id":"doi:10.1016/j.neuroimage.2014.02.029","doi":"https://doi.org/10.1016/j.neuroimage.2014.02.029","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.neuroimage.2014.02.029","pdf_url":"https://www.sciencedirect.com/science/article/pii/S1053811914001426/pdf","source":{"id":"https://openalex.org/S103225281","display_name":"NeuroImage","issn_l":"1053-8119","issn":["1053-8119","1095-9572"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-1","medline","norway-2","poland-140","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"NeuroImage","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://www.sciencedirect.com/science/article/pii/S1053811914001426/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5084364544","display_name":"Karen J. Mullinger","orcid":"https://orcid.org/0000-0002-8164-0274","observed_orcids":["https://orcid.org/0000-0002-8164-0274"]},"institutions":[{"id":"https://openalex.org/I142263535","display_name":"University of Nottingham","ror":"https://ror.org/01ee9ar58","country_code":"GB","type":"education","lineage":["https://openalex.org/I142263535"]},{"id":"https://openalex.org/I79619799","display_name":"University of Birmingham","ror":"https://ror.org/03angcq70","country_code":"GB","type":"education","lineage":["https://openalex.org/I79619799"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"K.J. Mullinger","raw_affiliation_strings":["Sir Peter Mansfield Magnetic Resonance Centre, School of Physics and Astronomy, University of Nottingham, Nottingham, UK; Birmingham University Imaging Centre, School of Psychology, University of Birmingham, Birmingham, UK. Electronic address: karen.mullinger@nottingham.ac.uk","Birmingham University Imaging Centre, School of Psychology, University of Birmingham, Birmingham, UK","Sir Peter Mansfield Magnetic Resonance Centre, School of Physics and Astronomy, University of Nottingham, Nottingham, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sir Peter Mansfield Magnetic Resonance Centre, School of Physics and Astronomy, University of Nottingham, Nottingham, UK; Birmingham University Imaging Centre, School of Psychology, University of Birmingham, Birmingham, UK. Electronic address: karen.mullinger@nottingham.ac.uk","institution_ids":["https://openalex.org/I142263535","https://openalex.org/I79619799"]},{"raw_affiliation_string":"Birmingham University Imaging Centre, School of Psychology, University of Birmingham, Birmingham, UK","institution_ids":["https://openalex.org/I79619799"]},{"raw_affiliation_string":"Sir Peter Mansfield Magnetic Resonance Centre, School of Physics and Astronomy, University of Nottingham, Nottingham, UK","institution_ids":["https://openalex.org/I142263535"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014763831","display_name":"Stephen D. Mayhew","orcid":"https://orcid.org/0000-0003-1240-1488","observed_orcids":["https://orcid.org/0000-0003-1240-1488"]},"institutions":[{"id":"https://openalex.org/I79619799","display_name":"University of Birmingham","ror":"https://ror.org/03angcq70","country_code":"GB","type":"education","lineage":["https://openalex.org/I79619799"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"S.D. Mayhew","raw_affiliation_strings":["Birmingham University Imaging Centre, School of Psychology, University of Birmingham, Birmingham, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Birmingham University Imaging Centre, School of Psychology, University of Birmingham, Birmingham, UK","institution_ids":["https://openalex.org/I79619799"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011445411","display_name":"Andrew P. Bagshaw","orcid":"https://orcid.org/0000-0001-6217-1292","observed_orcids":["https://orcid.org/0000-0001-6217-1292"]},"institutions":[{"id":"https://openalex.org/I79619799","display_name":"University of Birmingham","ror":"https://ror.org/03angcq70","country_code":"GB","type":"education","lineage":["https://openalex.org/I79619799"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"A.P. Bagshaw","raw_affiliation_strings":["Birmingham University Imaging Centre, School of Psychology, University of Birmingham, Birmingham, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Birmingham University Imaging Centre, School of Psychology, University of Birmingham, Birmingham, UK","institution_ids":["https://openalex.org/I79619799"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086224910","display_name":"Richard W Bowtell","orcid":"https://orcid.org/0000-0001-8656-412X","observed_orcids":["https://orcid.org/0000-0001-8656-412X"]},"institutions":[{"id":"https://openalex.org/I142263535","display_name":"University of Nottingham","ror":"https://ror.org/01ee9ar58","country_code":"GB","type":"education","lineage":["https://openalex.org/I142263535"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"R. Bowtell","raw_affiliation_strings":["Sir Peter Mansfield Magnetic Resonance Centre, School of Physics and Astronomy, University of Nottingham, Nottingham, UK","Sir Peter Mansfield Magnetic Resonance Centre School of Physics and Astronomy, University of Nottingham, Nottingham, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sir Peter Mansfield Magnetic Resonance Centre, School of Physics and Astronomy, University of Nottingham, Nottingham, UK","institution_ids":["https://openalex.org/I142263535"]},{"raw_affiliation_string":"Sir Peter Mansfield Magnetic Resonance Centre School of Physics and Astronomy, University of Nottingham, Nottingham, UK","institution_ids":["https://openalex.org/I142263535"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5031505814","display_name":"Susan Francis","orcid":"https://orcid.org/0000-0003-0903-7507","observed_orcids":["https://orcid.org/0000-0003-0903-7507"]},"institutions":[{"id":"https://openalex.org/I142263535","display_name":"University of Nottingham","ror":"https://ror.org/01ee9ar58","country_code":"GB","type":"education","lineage":["https://openalex.org/I142263535"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"S.T. Francis","raw_affiliation_strings":["Sir Peter Mansfield Magnetic Resonance Centre, School of Physics and Astronomy, University of Nottingham, Nottingham, UK","Sir Peter Mansfield Magnetic Resonance Centre School of Physics and Astronomy, University of Nottingham, Nottingham, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sir Peter Mansfield Magnetic Resonance Centre, School of Physics and Astronomy, University of Nottingham, Nottingham, UK","institution_ids":["https://openalex.org/I142263535"]},{"raw_affiliation_string":"Sir Peter Mansfield Magnetic Resonance Centre School of Physics and Astronomy, University of Nottingham, Nottingham, UK","institution_ids":["https://openalex.org/I142263535"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5084364544"],"corresponding_institution_ids":["https://openalex.org/I142263535","https://openalex.org/I79619799"],"apc_list":{"value":3540,"currency":"USD","value_usd":3540},"apc_paid":{"value":3540,"currency":"USD","value_usd":3540},"fwci":12.0219,"has_fulltext":true,"cited_by_count":155,"citation_normalized_percentile":{"value":0.99188051,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":100},"biblio":{"volume":"94","issue":null,"first_page":"263","last_page":"274"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10378","display_name":"Advanced MRI Techniques and Applications","score":0.9731000065803528,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10378","display_name":"Advanced MRI Techniques and Applications","score":0.9731000065803528,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11304","display_name":"Advanced Neuroimaging Techniques and Applications","score":0.01269999984651804,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10977","display_name":"Optical Imaging and Spectroscopy Techniques","score":0.003599999938160181,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/negative-bold-response","display_name":"negative BOLD response","score":0.996999979019165},{"id":"https://openalex.org/keywords/neurovascular-coupling","display_name":"neurovascular coupling","score":0.9480000138282776},{"id":"https://openalex.org/keywords/cerebral-blood-flow","display_name":"cerebral blood flow","score":0.8289999961853027},{"id":"https://openalex.org/keywords/cerebral-metabolic-rate-for-oxygen","display_name":"cerebral oxygen consumption","score":0.8180000185966492},{"id":"https://openalex.org/keywords/primary-somatosensory-cortex","display_name":"primary somatosensory cortex","score":0.7670000195503235},{"id":"https://openalex.org/keywords/median-nerve-stimulation","display_name":"median nerve stimulation","score":0.9700000286102295},{"id":"https://openalex.org/keywords/somatosensory-evoked-potentials","display_name":"somatosensory evoked potentials","score":0.9649999737739563},{"id":"https://openalex.org/keywords/cortical-inhibition","display_name":"cortical inhibition","score":0.9200000166893005}],"concepts":[{"id":"https://openalex.org/C172497186","wikidata":"https://www.wikidata.org/wiki/Q328835","display_name":"Somatosensory system","level":2,"score":0.7138028740882874},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.6558204889297485},{"id":"https://openalex.org/C522805319","wikidata":"https://www.wikidata.org/wiki/Q179965","display_name":"Electroencephalography","level":2,"score":0.6124253273010254},{"id":"https://openalex.org/C185263204","wikidata":"https://www.wikidata.org/wiki/Q1154774","display_name":"Electrophysiology","level":2,"score":0.5925597548484802},{"id":"https://openalex.org/C161941745","wikidata":"https://www.wikidata.org/wiki/Q1572478","display_name":"Somatosensory evoked potential","level":2,"score":0.5674240589141846},{"id":"https://openalex.org/C26170363","wikidata":"https://www.wikidata.org/wiki/Q1981408","display_name":"Haemodynamic response","level":4,"score":0.5544141530990601},{"id":"https://openalex.org/C125990524","wikidata":"https://www.wikidata.org/wiki/Q5322921","display_name":"EEG-fMRI","level":3,"score":0.5335697531700134},{"id":"https://openalex.org/C157767197","wikidata":"https://www.wikidata.org/wiki/Q886843","display_name":"Cerebral blood flow","level":2,"score":0.5184063911437988},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.4402647912502289},{"id":"https://openalex.org/C24998067","wikidata":"https://www.wikidata.org/wiki/Q4114622","display_name":"Stimulation","level":2,"score":0.4132010340690613},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.29809969663619995},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.23425966501235962},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2167358100414276},{"id":"https://openalex.org/C2777953023","wikidata":"https://www.wikidata.org/wiki/Q1073121","display_name":"Heart rate","level":3,"score":0.11469975113868713},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001931","descriptor_name":"Brain Mapping","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D001931","descriptor_name":"Brain Mapping","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D001931","descriptor_name":"Brain Mapping","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D002560","descriptor_name":"Cerebrovascular Circulation","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D002560","descriptor_name":"Cerebrovascular Circulation","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D002560","descriptor_name":"Cerebrovascular Circulation","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D004561","descriptor_name":"Transcutaneous Electric Nerve Stimulation","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D004561","descriptor_name":"Transcutaneous Electric Nerve Stimulation","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D004561","descriptor_name":"Transcutaneous Electric Nerve Stimulation","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D004569","descriptor_name":"Electroencephalography","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D004569","descriptor_name":"Electroencephalography","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D004569","descriptor_name":"Electroencephalography","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D005071","descriptor_name":"Evoked Potentials","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D005071","descriptor_name":"Evoked Potentials","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D005071","descriptor_name":"Evoked Potentials","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008475","descriptor_name":"Median Nerve","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D008475","descriptor_name":"Median Nerve","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D008475","descriptor_name":"Median Nerve","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009433","descriptor_name":"Neural Inhibition","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009433","descriptor_name":"Neural Inhibition","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009433","descriptor_name":"Neural Inhibition","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D010101","descriptor_name":"Oxygen Consumption","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D010101","descriptor_name":"Oxygen Consumption","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D010101","descriptor_name":"Oxygen Consumption","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D066191","descriptor_name":"Sensorimotor Cortex","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D066191","descriptor_name":"Sensorimotor Cortex","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D066191","descriptor_name":"Sensorimotor Cortex","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false}],"locations_count":6,"locations":[{"id":"doi:10.1016/j.neuroimage.2014.02.029","doi":"https://doi.org/10.1016/j.neuroimage.2014.02.029","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.neuroimage.2014.02.029","pdf_url":"https://www.sciencedirect.com/science/article/pii/S1053811914001426/pdf","source":{"id":"https://openalex.org/S103225281","display_name":"NeuroImage","issn_l":"1053-8119","issn":["1053-8119","1095-9572"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-1","medline","norway-2","poland-140","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"NeuroImage","raw_type":"journal-article"},{"id":"pmid:24632092","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24632092","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"NeuroImage","raw_type":"Journal Article"},{"id":"pmh:oai:nottingham-repository.worktribe.com:729731","doi":null,"is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.neuroimage.2014.02.029","pdf_url":null,"source":{"id":"https://openalex.org/S4306402483","display_name":"Repository@Nottingham (University of Nottingham)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I142263535","host_organization_name":"University of Nottingham","host_organization_lineage":["https://openalex.org/I142263535"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Journal Article"},{"id":"pmh:oai:eprints.nottingham.ac.uk:35148","doi":null,"is_oa":true,"landing_page_url":"http://eprints.nottingham.ac.uk/35148/","pdf_url":null,"source":{"id":"https://openalex.org/S4306402014","display_name":"Nottingham ePrints (University of Nottingham)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I142263535","host_organization_name":"University of Nottingham","host_organization_lineage":["https://openalex.org/I142263535"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Article"},{"id":"pmh:oai:https://nottingham-repository.worktribe.com/:729731","doi":null,"is_oa":true,"landing_page_url":"https://nottingham-repository.worktribe.com/output/729731","pdf_url":null,"source":{"id":"https://openalex.org/S4306402483","display_name":"Repository@Nottingham (University of Nottingham)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I142263535","host_organization_name":"University of Nottingham","host_organization_lineage":["https://openalex.org/I142263535"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Journal Article"},{"id":"pmh:oai:pure.atira.dk:openaire_cris_publications/19e721cf-56b4-4d25-bdd0-ca8e1381bfaf","doi":null,"is_oa":true,"landing_page_url":"https://research.birmingham.ac.uk/en/publications/19e721cf-56b4-4d25-bdd0-ca8e1381bfaf","pdf_url":null,"source":{"id":"https://openalex.org/S4306402634","display_name":"University of Birmingham Research Portal (University of Birmingham)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I79619799","host_organization_name":"University of Birmingham","host_organization_lineage":["https://openalex.org/I79619799"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Mullinger, K, Mayhew, S, Bagshaw, A, Bowtell, R & Francis, S T 2014, 'Evidence that the negative BOLD response is neuronal in origin : A simultaneous EEG\u2013BOLD\u2013CBF study in humans', NeuroImage, vol. 94, pp. 263-274. https://doi.org/10.1016/j.neuroimage.2014.02.029","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1016/j.neuroimage.2014.02.029","doi":"https://doi.org/10.1016/j.neuroimage.2014.02.029","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.neuroimage.2014.02.029","pdf_url":"https://www.sciencedirect.com/science/article/pii/S1053811914001426/pdf","source":{"id":"https://openalex.org/S103225281","display_name":"NeuroImage","issn_l":"1053-8119","issn":["1053-8119","1095-9572"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-1","medline","norway-2","poland-140","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"NeuroImage","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.8199999928474426,"id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G2946728145","display_name":null,"funder_award_id":"EP/I022325/1","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"},{"id":"https://openalex.org/G3782905169","display_name":null,"funder_award_id":"EP/F023057/1","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"},{"id":"https://openalex.org/G5340163802","display_name":null,"funder_award_id":"EP/F023057/1","funder_id":"https://openalex.org/F4320320672","funder_display_name":"South African Medical Research Council"},{"id":"https://openalex.org/G5498004739","display_name":null,"funder_award_id":"G0901321","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"},{"id":"https://openalex.org/G6070455118","display_name":"Development of human EEG-ASL-BOLD neuroimaging and math modelling framework to quantify neuronal, haemodynamic and metabolic responses to stimulation","funder_award_id":"EP/I022325/1","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"},{"id":"https://openalex.org/G6204919770","display_name":null,"funder_award_id":"EP/J006823/1","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"},{"id":"https://openalex.org/G726753553","display_name":"Development of Single Trial EEG-fMRI: Investigations of Dynamic Brain Function at High Temporal and Spatial Resolution","funder_award_id":"EP/F023057/1","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"},{"id":"https://openalex.org/G8156147549","display_name":"Understanding and reducing artefacts in simultaneously acquired EEG and fMRI data","funder_award_id":"EP/J006823/1","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"},{"id":"https://openalex.org/G8611746019","display_name":null,"funder_award_id":"G0901321","funder_id":"https://openalex.org/F4320320324","funder_display_name":"University of Nottingham"}],"funders":[{"id":"https://openalex.org/F4320320324","display_name":"University of Nottingham","ror":"https://ror.org/01ee9ar58"},{"id":"https://openalex.org/F4320320672","display_name":"South African Medical Research Council","ror":"https://ror.org/05q60vz69"},{"id":"https://openalex.org/F4320334626","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517"},{"id":"https://openalex.org/F4320334627","display_name":"Engineering and Physical Sciences Research Council","ror":"https://ror.org/0439y7842"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2103333652.pdf","grobid_xml":"https://content.openalex.org/works/W2103333652.grobid-xml"},"referenced_works_count":105,"referenced_works":["https://openalex.org/W122066951","https://openalex.org/W1530245994","https://openalex.org/W1596040508","https://openalex.org/W1964483159","https://openalex.org/W1967825340","https://openalex.org/W1969991077","https://openalex.org/W1970991309","https://openalex.org/W1976590901","https://openalex.org/W1979240985","https://openalex.org/W1980446678","https://openalex.org/W1982678265","https://openalex.org/W1984867971","https://openalex.org/W1988794652","https://openalex.org/W1988981753","https://openalex.org/W1994156254","https://openalex.org/W1996538430","https://openalex.org/W1997027149","https://openalex.org/W1999512151","https://openalex.org/W2000247542","https://openalex.org/W2000790011","https://openalex.org/W2001428189","https://openalex.org/W2001467170","https://openalex.org/W2002229750","https://openalex.org/W2004031813","https://openalex.org/W2007377538","https://openalex.org/W2010587277","https://openalex.org/W2011367324","https://openalex.org/W2011958935","https://openalex.org/W2018108370","https://openalex.org/W2018368492","https://openalex.org/W2022609478","https://openalex.org/W2024875626","https://openalex.org/W2027063232","https://openalex.org/W2029120044","https://openalex.org/W2029609684","https://openalex.org/W2029934372","https://openalex.org/W2030261869","https://openalex.org/W2030418858","https://openalex.org/W2030737932","https://openalex.org/W2032845561","https://openalex.org/W2033400934","https://openalex.org/W2034500789","https://openalex.org/W2035001644","https://openalex.org/W2035572126","https://openalex.org/W2038590120","https://openalex.org/W2038840654","https://openalex.org/W2040558597","https://openalex.org/W2041226785","https://openalex.org/W2042522004","https://openalex.org/W2046389007","https://openalex.org/W2049679895","https://openalex.org/W2049903759","https://openalex.org/W2050506578","https://openalex.org/W2051332057","https://openalex.org/W2052644075","https://openalex.org/W2054851660","https://openalex.org/W2055526694","https://openalex.org/W2059919805","https://openalex.org/W2066439376","https://openalex.org/W2066488827","https://openalex.org/W2066712028","https://openalex.org/W2071714163","https://openalex.org/W2072298200","https://openalex.org/W2072522618","https://openalex.org/W2073321867","https://openalex.org/W2074155898","https://openalex.org/W2076023293","https://openalex.org/W2076816202","https://openalex.org/W2079034885","https://openalex.org/W2082499355","https://openalex.org/W2090781932","https://openalex.org/W2092791692","https://openalex.org/W2098182568","https://openalex.org/W2099023267","https://openalex.org/W2108673721","https://openalex.org/W2111177099","https://openalex.org/W2114104729","https://openalex.org/W2115549238","https://openalex.org/W2116392370","https://openalex.org/W2120078534","https://openalex.org/W2124661129","https://openalex.org/W2128946826","https://openalex.org/W2129530121","https://openalex.org/W2130038497","https://openalex.org/W2131996077","https://openalex.org/W2132872711","https://openalex.org/W2137328415","https://openalex.org/W2137877983","https://openalex.org/W2138092999","https://openalex.org/W2139354009","https://openalex.org/W2143117061","https://openalex.org/W2147075761","https://openalex.org/W2148211890","https://openalex.org/W2148992333","https://openalex.org/W2152346792","https://openalex.org/W2156374963","https://openalex.org/W2156824864","https://openalex.org/W2159542245","https://openalex.org/W2159934864","https://openalex.org/W2161701162","https://openalex.org/W2163234334","https://openalex.org/W2167981126","https://openalex.org/W2168496368","https://openalex.org/W2168822643","https://openalex.org/W4231963173"],"related_works":["https://openalex.org/W2409609011","https://openalex.org/W2101129538","https://openalex.org/W1973073550","https://openalex.org/W4294666520","https://openalex.org/W1969991077","https://openalex.org/W2566403830","https://openalex.org/W4250635985","https://openalex.org/W2020016902","https://openalex.org/W2144707573","https://openalex.org/W4386587147"],"abstract_inverted_index":{"Unambiguous":[0],"interpretation":[1],"of":[2,11,32,57,84,104,171,189,204,254],"changes":[3,18],"in":[4,19,63,80,99,108,123,131,153,161,184,245],"the":[5,12,23,29,33,67,81,85,100,132,169,172,186,222,226,237,247,251,255],"BOLD":[6,35,71,142,191],"signal":[7],"is":[8],"challenging":[9],"because":[10],"complex":[13],"neurovascular":[14,233],"coupling":[15,114,234],"that":[16,94,138,217,225,240],"translates":[17],"neuronal":[20,219],"activity":[21],"into":[22],"subsequent":[24],"haemodynamic":[25],"response.":[26],"In":[27],"particular,":[28],"neurophysiological":[30,252],"origin":[31],"negative":[34,70,73,190],"response":[36,143,159],"(NBR)":[37],"remains":[38],"incompletely":[39],"understood.":[40],"Here,":[41],"we":[42],"simultaneously":[43],"recorded":[44],"BOLD,":[45],"EEG":[46,175],"and":[47,72,91,145,149,178,192,207],"cerebral":[48,101],"blood":[49],"flow":[50],"(CBF)":[51],"responses":[52,75,194],"to":[53,65,76,119,236],"10":[54],"s":[55],"blocks":[56],"unilateral":[58],"median":[59],"nerve":[60],"stimulation":[61],"(MNS)":[62],"order":[64],"interrogate":[66],"NBR.":[68],"Both":[69],"CBF":[74,147,193],"MNS":[77,95],"were":[78],"observed":[79],"same":[82],"region":[83,127,137],"ipsilateral":[86,125,162],"primary":[87],"sensorimotor":[88],"cortex":[89],"(S1/M1)":[90],"calculations":[92],"showed":[93,197],"induced":[96],"a":[97,140,150,218,231],"decrease":[98],"metabolic":[102],"rate":[103],"oxygen":[105],"consumption":[106],"(CMRO2)":[107],"this":[109,124],"NBR":[110,227,248],"region.":[111],"The":[112,157],"\u2206CMRO2/\u2206CBF":[113],"ratio":[115],"(n)":[116],"was":[117,164],"found":[118],"be":[120,243],"significantly":[121],"larger":[122],"S1/M1":[126,134,163],"(n=0.91\u00b10.04,":[128],"M=10.45%)":[129,136],"than":[130],"contralateral":[133],"(n=0.65\u00b10.03,":[135],"exhibited":[139],"positive":[141,146],"(PBR)":[144],"response,":[148],"consequent":[151],"increase":[152],"CMRO2":[154],"during":[155],"MNS.":[156],"fMRI":[158],"amplitude":[160],"negatively":[165],"correlated":[166],"with":[167],"both":[168],"power":[170],"8-13":[173],"Hz":[174],"mu":[176,199],"oscillation":[177],"somatosensory":[179,209],"evoked":[180,210],"potential":[181],"amplitude.":[182],"Blocks":[183],"which":[185],"largest":[187,208],"magnitude":[188],"occurred":[195],"therefore":[196],"greatest":[198],"power,":[200],"an":[201],"electrophysiological":[202],"index":[203],"cortical":[205],"inhibition,":[206],"potentials.":[211],"Taken":[212],"together,":[213],"our":[214],"results":[215],"suggest":[216],"mechanism":[220,235],"underlies":[221],"NBR,":[223],"but":[224],"may":[228],"originate":[229],"from":[230],"different":[232],"PBR,":[238],"suggesting":[239],"caution":[241],"should":[242],"taken":[244],"assuming":[246],"simply":[249],"represents":[250],"inverse":[253],"PBR.":[256]},"counts_by_year":[{"year":2026,"cited_by_count":9},{"year":2025,"cited_by_count":9},{"year":2024,"cited_by_count":8},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":14},{"year":2021,"cited_by_count":27},{"year":2020,"cited_by_count":11},{"year":2019,"cited_by_count":13},{"year":2018,"cited_by_count":13},{"year":2017,"cited_by_count":11},{"year":2016,"cited_by_count":15},{"year":2015,"cited_by_count":10},{"year":2014,"cited_by_count":14}],"updated_date":"2026-10-17T09:40:24.721904","created_date":"2025-10-10T00:00:00"}