{"id":"https://openalex.org/W2103096891","doi":"https://doi.org/10.1128/jb.179.6.2022-2028.1997","title":"Biosynthesis of riboflavin: characterization of the bifunctional deaminase-reductase of Escherichia coli and Bacillus subtilis","display_name":"Biosynthesis of riboflavin: characterization of the bifunctional deaminase-reductase of Escherichia coli and Bacillus subtilis","publication_year":1997,"publication_date":"1997-03-01","ids":{"openalex":"https://openalex.org/W2103096891","doi":"https://doi.org/10.1128/jb.179.6.2022-2028.1997","mag":"2103096891","pmid":"https://pubmed.ncbi.nlm.nih.gov/9068650","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/178928"},"language":"en","primary_location":{"id":"doi:10.1128/jb.179.6.2022-2028.1997","doi":"https://doi.org/10.1128/jb.179.6.2022-2028.1997","is_oa":false,"landing_page_url":"https://doi.org/10.1128/jb.179.6.2022-2028.1997","pdf_url":null,"source":{"id":"https://openalex.org/S133274750","display_name":"Journal of Bacteriology","issn_l":"0021-9193","issn":["0021-9193","1067-8832","1098-5530"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Bacteriology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://europepmc.org/pmc/articles/PMC178928","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5079134590","display_name":"Gerald Richter","orcid":"https://orcid.org/0000-0002-2870-1568","observed_orcids":["https://orcid.org/0000-0002-2870-1568"]},"institutions":[{"id":"https://openalex.org/I62916508","display_name":"Technical University of Munich","ror":"https://ror.org/02kkvpp62","country_code":"DE","type":"education","lineage":["https://openalex.org/I62916508"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"G Richter","raw_affiliation_strings":["Institut f\u00fcr Organische Chemie und Biochemie, Technische Universit\u00e4t M\u00fcnchen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut f\u00fcr Organische Chemie und Biochemie, Technische Universit\u00e4t M\u00fcnchen, Germany","institution_ids":["https://openalex.org/I62916508"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006304159","display_name":"Markus J. Fischer","orcid":"https://orcid.org/0000-0001-7243-4199","observed_orcids":["https://orcid.org/0000-0001-7243-4199"]},"institutions":[{"id":"https://openalex.org/I62916508","display_name":"Technical University of Munich","ror":"https://ror.org/02kkvpp62","country_code":"DE","type":"education","lineage":["https://openalex.org/I62916508"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"M Fischer","raw_affiliation_strings":["Institut f\u00fcr Organische Chemie und Biochemie, Technische Universit\u00e4t M\u00fcnchen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut f\u00fcr Organische Chemie und Biochemie, Technische Universit\u00e4t M\u00fcnchen, Germany","institution_ids":["https://openalex.org/I62916508"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074851336","display_name":"Cornelia Krieger","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I62916508","display_name":"Technical University of Munich","ror":"https://ror.org/02kkvpp62","country_code":"DE","type":"education","lineage":["https://openalex.org/I62916508"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"C Krieger","raw_affiliation_strings":["Institut f\u00fcr Organische Chemie und Biochemie, Technische Universit\u00e4t M\u00fcnchen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut f\u00fcr Organische Chemie und Biochemie, Technische Universit\u00e4t M\u00fcnchen, Germany","institution_ids":["https://openalex.org/I62916508"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090178867","display_name":"Sabine Eberhardt","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I62916508","display_name":"Technical University of Munich","ror":"https://ror.org/02kkvpp62","country_code":"DE","type":"education","lineage":["https://openalex.org/I62916508"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"S Eberhardt","raw_affiliation_strings":["Institut f\u00fcr Organische Chemie und Biochemie, Technische Universit\u00e4t M\u00fcnchen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut f\u00fcr Organische Chemie und Biochemie, Technische Universit\u00e4t M\u00fcnchen, Germany","institution_ids":["https://openalex.org/I62916508"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064453992","display_name":"Holger L\u00fcttgen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I62916508","display_name":"Technical University of Munich","ror":"https://ror.org/02kkvpp62","country_code":"DE","type":"education","lineage":["https://openalex.org/I62916508"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"H L\u00fcttgen","raw_affiliation_strings":["Institut f\u00fcr Organische Chemie und Biochemie, Technische Universit\u00e4t M\u00fcnchen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut f\u00fcr Organische Chemie und Biochemie, Technische Universit\u00e4t M\u00fcnchen, Germany","institution_ids":["https://openalex.org/I62916508"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077522892","display_name":"Ine Schaaff\u2010Gerstenschl\u00e4ger","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I62916508","display_name":"Technical University of Munich","ror":"https://ror.org/02kkvpp62","country_code":"DE","type":"education","lineage":["https://openalex.org/I62916508"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"I Gerstenschl\u00e4ger","raw_affiliation_strings":["Institut f\u00fcr Organische Chemie und Biochemie, Technische Universit\u00e4t M\u00fcnchen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut f\u00fcr Organische Chemie und Biochemie, Technische Universit\u00e4t M\u00fcnchen, Germany","institution_ids":["https://openalex.org/I62916508"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5068798153","display_name":"Adelbert Bacher","orcid":"https://orcid.org/0000-0001-5174-4139","observed_orcids":["https://orcid.org/0000-0001-5174-4139"]},"institutions":[{"id":"https://openalex.org/I62916508","display_name":"Technical University of Munich","ror":"https://ror.org/02kkvpp62","country_code":"DE","type":"education","lineage":["https://openalex.org/I62916508"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"A Bacher","raw_affiliation_strings":["Institut f\u00fcr Organische Chemie und Biochemie, Technische Universit\u00e4t M\u00fcnchen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut f\u00fcr Organische Chemie und Biochemie, Technische Universit\u00e4t M\u00fcnchen, Germany","institution_ids":["https://openalex.org/I62916508"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I62916508"],"apc_list":null,"apc_paid":null,"fwci":1.2901,"has_fulltext":false,"cited_by_count":111,"citation_normalized_percentile":{"value":0.79366689,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"179","issue":"6","first_page":"2022","last_page":"2028"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12827","display_name":"Biochemical and Molecular Research","score":0.9570000171661377,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12827","display_name":"Biochemical and Molecular Research","score":0.9570000171661377,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10499","display_name":"Folate and B Vitamins Research","score":0.017100000753998756,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10120","display_name":"Bacterial Genetics and Biotechnology","score":0.00570000009611249,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/riboflavin-biosynthesis","display_name":"riboflavin biosynthesis","score":1.0},{"id":"https://openalex.org/keywords/escherichia-coli","display_name":"Escherichia coli","score":0.9200000166893005},{"id":"https://openalex.org/keywords/bacillus-subtilis","display_name":"Bacillus subtilis","score":1.0},{"id":"https://openalex.org/keywords/deoxycytidylate-deaminase","display_name":"deoxycytidylate deaminase","score":0.9110000133514404},{"id":"https://openalex.org/keywords/recombinant-protein-expression","display_name":"recombinant protein expression","score":0.753000020980835}],"concepts":[{"id":"https://openalex.org/C2777272437","wikidata":"https://www.wikidata.org/wiki/Q131238","display_name":"Bacillus subtilis","level":3,"score":0.818361759185791},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.793095588684082},{"id":"https://openalex.org/C547475151","wikidata":"https://www.wikidata.org/wiki/Q25419","display_name":"Escherichia coli","level":3,"score":0.7242136001586914},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.7093760967254639},{"id":"https://openalex.org/C203075996","wikidata":"https://www.wikidata.org/wiki/Q139677","display_name":"Operon","level":4,"score":0.6416322588920593},{"id":"https://openalex.org/C134651460","wikidata":"https://www.wikidata.org/wiki/Q3100717","display_name":"Reductase","level":3,"score":0.5882812738418579},{"id":"https://openalex.org/C71995715","wikidata":"https://www.wikidata.org/wiki/Q78574842","display_name":"Flavoprotein","level":3,"score":0.4377817213535309},{"id":"https://openalex.org/C104788683","wikidata":"https://www.wikidata.org/wiki/Q259292","display_name":"7-Dehydrocholesterol reductase","level":4,"score":0.4329943358898163},{"id":"https://openalex.org/C58431802","wikidata":"https://www.wikidata.org/wiki/Q420663","display_name":"Phosphofructokinase 2","level":3,"score":0.42063796520233154},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.39943480491638184},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.3334411382675171},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.21933698654174805},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.09921854734420776},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.09029528498649597}],"mesh":[{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001412","descriptor_name":"Bacillus subtilis","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":true},{"descriptor_ui":"D001412","descriptor_name":"Bacillus subtilis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001426","descriptor_name":"Bacterial Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004926","descriptor_name":"Escherichia coli","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":true},{"descriptor_ui":"D004926","descriptor_name":"Escherichia coli","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D005798","descriptor_name":"Genes, Bacterial","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009243","descriptor_name":"NAD","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009249","descriptor_name":"NADP","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009709","descriptor_name":"Nucleotide Deaminases","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009709","descriptor_name":"Nucleotide Deaminases","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D009709","descriptor_name":"Nucleotide Deaminases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D009709","descriptor_name":"Nucleotide Deaminases","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D010957","descriptor_name":"Plasmids","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011994","descriptor_name":"Recombinant Proteins","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D011994","descriptor_name":"Recombinant Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011994","descriptor_name":"Recombinant Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D012256","descriptor_name":"Riboflavin","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":true},{"descriptor_ui":"D013401","descriptor_name":"Sugar Alcohol Dehydrogenases","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D013401","descriptor_name":"Sugar Alcohol Dehydrogenases","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D013401","descriptor_name":"Sugar Alcohol Dehydrogenases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D013401","descriptor_name":"Sugar Alcohol Dehydrogenases","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D016415","descriptor_name":"Sequence Alignment","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D029968","descriptor_name":"Escherichia coli Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":5,"locations":[{"id":"doi:10.1128/jb.179.6.2022-2028.1997","doi":"https://doi.org/10.1128/jb.179.6.2022-2028.1997","is_oa":false,"landing_page_url":"https://doi.org/10.1128/jb.179.6.2022-2028.1997","pdf_url":null,"source":{"id":"https://openalex.org/S133274750","display_name":"Journal of Bacteriology","issn_l":"0021-9193","issn":["0021-9193","1067-8832","1098-5530"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Bacteriology","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:150839","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC178928","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:178928","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/178928","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Bacteriol","raw_type":"Text"},{"id":"pmid:9068650","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9068650","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of bacteriology","raw_type":"Journal Article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.424.5101","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.424.5101","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://jb.asm.org/content/179/6/2022.full.pdf","raw_type":"text"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:150839","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC178928","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320320879","display_name":"Deutsche Forschungsgemeinschaft","ror":"https://ror.org/018mejw64"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":24,"referenced_works":["https://openalex.org/W183702131","https://openalex.org/W188468884","https://openalex.org/W952959173","https://openalex.org/W988472416","https://openalex.org/W1487867154","https://openalex.org/W1487894348","https://openalex.org/W1530882501","https://openalex.org/W1546871351","https://openalex.org/W1596533796","https://openalex.org/W1608820817","https://openalex.org/W1844536398","https://openalex.org/W1921178109","https://openalex.org/W1971974110","https://openalex.org/W2010786034","https://openalex.org/W2018573392","https://openalex.org/W2019410656","https://openalex.org/W2040818261","https://openalex.org/W2055015377","https://openalex.org/W2062468764","https://openalex.org/W2071744636","https://openalex.org/W2094095270","https://openalex.org/W2263491553","https://openalex.org/W2338653879","https://openalex.org/W6628636579"],"related_works":["https://openalex.org/W2408232901","https://openalex.org/W1596533796","https://openalex.org/W1975886495","https://openalex.org/W7097205371","https://openalex.org/W1967937950","https://openalex.org/W2092432318","https://openalex.org/W2019310413","https://openalex.org/W1535184858","https://openalex.org/W2807072788","https://openalex.org/W2415463102"],"abstract_inverted_index":{"The":[0,42,98],"ribG":[1,43,111],"gene":[2,38,44,51,105,112],"at":[3,18],"the":[4,8,22,36,49,71,77,82,89,93,103,110,132,141,147,159],"5'":[5],"end":[6],"of":[7,11,39,45,52,79,84,92,106,113,134,140,146],"riboflavin":[9],"operon":[10],"Bacillus":[12],"subtilis":[13,47,115],"and":[14,34,48,62,73,88,109],"a":[15,129],"reading":[16],"frame":[17],"442":[19],"kb":[20],"on":[21],"Escherichia":[23],"coli":[24,54,60,108],"chromosome":[25],"(subsequently":[26],"designated":[27],"ribD)":[28],"show":[29],"similarity":[30],"with":[31,35,152],"deoxycytidylate":[32],"deaminase":[33,153],"RIB7":[37],"Saccharomyces":[40],"cerevisiae.":[41],"B.":[46,114],"ribD":[50,104],"E.":[53,59,107],"were":[55,63,116,162],"expressed":[56],"in":[57,76],"recombinant":[58,99],"strains":[61],"shown":[64],"to":[65,118],"code":[66],"for":[67,131],"bifunctional":[68],"proteins":[69,100,151,161],"catalyzing":[70],"second":[72],"third":[74],"steps":[75],"biosynthesis":[78],"riboflavin,":[80],"i.e.,":[81],"deamination":[83],"2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone":[85],"5'-phosphate":[86],"(deaminase)":[87],"subsequent":[90],"reduction":[91],"ribosyl":[94],"side":[95],"chain":[96],"(reductase).":[97],"specified":[101],"by":[102],"purified":[117],"homogeneity.":[119],"NADH":[120],"as":[121,123,128],"well":[122],"NADPH":[124],"can":[125],"be":[126],"used":[127],"cosubstrate":[130],"reductase":[133,155],"both":[135],"microorganisms":[136],"under":[137],"study.":[138],"Expression":[139],"N-terminal":[142],"or":[143,154],"C-terminal":[144],"part":[145],"RibG":[148],"protein":[149],"yielded":[150],"activity,":[156],"respectively;":[157],"however,":[158],"truncated":[160],"rather":[163],"unstable.":[164]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":6},{"year":2015,"cited_by_count":5},{"year":2014,"cited_by_count":4},{"year":2013,"cited_by_count":6},{"year":2012,"cited_by_count":3}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}