{"id":"https://openalex.org/W2103073111","doi":"https://doi.org/10.1016/j.clae.2014.04.005","title":"Analysis of release kinetics of ocular therapeutics from drug releasing contact lenses: Best methods and practices to advance the field","display_name":"Analysis of release kinetics of ocular therapeutics from drug releasing contact lenses: Best methods and practices to advance the field","publication_year":2014,"publication_date":"2014-06-02","ids":{"openalex":"https://openalex.org/W2103073111","doi":"https://doi.org/10.1016/j.clae.2014.04.005","mag":"2103073111","pmid":"https://pubmed.ncbi.nlm.nih.gov/24894544"},"language":"en","primary_location":{"id":"doi:10.1016/j.clae.2014.04.005","doi":"https://doi.org/10.1016/j.clae.2014.04.005","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.clae.2014.04.005","pdf_url":null,"source":{"id":"https://openalex.org/S137552098","display_name":"Contact Lens and Anterior Eye","issn_l":"1367-0484","issn":["1367-0484","1476-5411"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Contact Lens and Anterior Eye","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5026085779","display_name":"Arianna Tieppo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I82497590","display_name":"Auburn University","ror":"https://ror.org/02v80fc35","country_code":"US","type":"education","lineage":["https://openalex.org/I82497590"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Arianna Tieppo","raw_affiliation_strings":["Biomimetic & Biohybrid Materials, Biomedical Devices, & Drug Delivery Laboratories, Department of Chemical Engineering, Auburn University, Auburn, AL 36849-5127, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomimetic & Biohybrid Materials, Biomedical Devices, & Drug Delivery Laboratories, Department of Chemical Engineering, Auburn University, Auburn, AL 36849-5127, USA","institution_ids":["https://openalex.org/I82497590"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019257231","display_name":"Aarika C. Boggs","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I82497590","display_name":"Auburn University","ror":"https://ror.org/02v80fc35","country_code":"US","type":"education","lineage":["https://openalex.org/I82497590"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Aarika C. Boggs","raw_affiliation_strings":["Biomimetic & Biohybrid Materials, Biomedical Devices, & Drug Delivery Laboratories, Department of Chemical Engineering, Auburn University, Auburn, AL 36849-5127, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomimetic & Biohybrid Materials, Biomedical Devices, & Drug Delivery Laboratories, Department of Chemical Engineering, Auburn University, Auburn, AL 36849-5127, USA","institution_ids":["https://openalex.org/I82497590"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083649152","display_name":"Payam Pourjavad","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I82497590","display_name":"Auburn University","ror":"https://ror.org/02v80fc35","country_code":"US","type":"education","lineage":["https://openalex.org/I82497590"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Payam Pourjavad","raw_affiliation_strings":["Biomimetic & Biohybrid Materials, Biomedical Devices, & Drug Delivery Laboratories, Department of Chemical Engineering, Auburn University, Auburn, AL 36849-5127, USA; NSF REU Site in Micro-Nano Structured Materials, Therapeutics, and Devices, Auburn University, Auburn, AL 36849-5127, USA","Biomimetic & Biohybrid Materials, Biomedical Devices, & Drug Delivery Laboratories, Department of Chemical Engineering, Auburn University, Auburn, AL 36849-5127, USA","NSF REU Site in Micro-Nano Structured Materials, Therapeutics, and Devices, Auburn University, Auburn, AL 36849-5127, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomimetic & Biohybrid Materials, Biomedical Devices, & Drug Delivery Laboratories, Department of Chemical Engineering, Auburn University, Auburn, AL 36849-5127, USA; NSF REU Site in Micro-Nano Structured Materials, Therapeutics, and Devices, Auburn University, Auburn, AL 36849-5127, USA","institution_ids":["https://openalex.org/I82497590"]},{"raw_affiliation_string":"Biomimetic & Biohybrid Materials, Biomedical Devices, & Drug Delivery Laboratories, Department of Chemical Engineering, Auburn University, Auburn, AL 36849-5127, USA","institution_ids":["https://openalex.org/I82497590"]},{"raw_affiliation_string":"NSF REU Site in Micro-Nano Structured Materials, Therapeutics, and Devices, Auburn University, Auburn, AL 36849-5127, USA","institution_ids":["https://openalex.org/I82497590"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5033345233","display_name":"Mark Edward Byrne","orcid":"https://orcid.org/0000-0001-7038-7042","observed_orcids":["https://orcid.org/0000-0001-7038-7042"]},"institutions":[{"id":"https://openalex.org/I82497590","display_name":"Auburn University","ror":"https://ror.org/02v80fc35","country_code":"US","type":"education","lineage":["https://openalex.org/I82497590"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Mark E. Byrne","raw_affiliation_strings":["Biomimetic & Biohybrid Materials, Biomedical Devices, & Drug Delivery Laboratories, Department of Chemical Engineering, Auburn University, Auburn, AL 36849-5127, USA; NSF REU Site in Micro-Nano Structured Materials, Therapeutics, and Devices, Auburn University, Auburn, AL 36849-5127, USA. Electronic address: byrneme@eng.auburn.edu","Biomimetic & Biohybrid Materials, Biomedical Devices, & Drug Delivery Laboratories, Department of Chemical Engineering, Auburn University, Auburn, AL 36849-5127, USA","NSF REU Site in Micro-Nano Structured Materials, Therapeutics, and Devices, Auburn University, Auburn, AL 36849-5127, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomimetic & Biohybrid Materials, Biomedical Devices, & Drug Delivery Laboratories, Department of Chemical Engineering, Auburn University, Auburn, AL 36849-5127, USA; NSF REU Site in Micro-Nano Structured Materials, Therapeutics, and Devices, Auburn University, Auburn, AL 36849-5127, USA. Electronic address: byrneme@eng.auburn.edu","institution_ids":["https://openalex.org/I82497590"]},{"raw_affiliation_string":"Biomimetic & Biohybrid Materials, Biomedical Devices, & Drug Delivery Laboratories, Department of Chemical Engineering, Auburn University, Auburn, AL 36849-5127, USA","institution_ids":["https://openalex.org/I82497590"]},{"raw_affiliation_string":"NSF REU Site in Micro-Nano Structured Materials, Therapeutics, and Devices, Auburn University, Auburn, AL 36849-5127, USA","institution_ids":["https://openalex.org/I82497590"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5033345233"],"corresponding_institution_ids":["https://openalex.org/I82497590"],"apc_list":{"value":3740,"currency":"USD","value_usd":3740},"apc_paid":null,"fwci":3.2081,"has_fulltext":false,"cited_by_count":50,"citation_normalized_percentile":{"value":0.91481635,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"37","issue":"4","first_page":"305","last_page":"313"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10920","display_name":"Advanced Drug Delivery Systems","score":0.9526000022888184,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10920","display_name":"Advanced Drug Delivery Systems","score":0.9526000022888184,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10997","display_name":"Ocular Surface and Contact Lens","score":0.04320000112056732,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10343","display_name":"Hydrogels: synthesis, properties, applications","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/1313","display_name":"Molecular Medicine"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/drug-release-kinetics","display_name":"drug release kinetics","score":0.8199999928474426},{"id":"https://openalex.org/keywords/therapeutic-contact-lenses","display_name":"therapeutic contact lenses","score":0.8450000286102295},{"id":"https://openalex.org/keywords/ocular-drug-delivery","display_name":"ocular drug delivery","score":0.8820000290870667},{"id":"https://openalex.org/keywords/controlled-drug-release","display_name":"controlled drug release","score":0.703000009059906},{"id":"https://openalex.org/keywords/solvent-exchange","display_name":"solvent exchange","score":0.6790000200271606},{"id":"https://openalex.org/keywords/mixing-rate","display_name":"mixing rate","score":0.8820000290870667},{"id":"https://openalex.org/keywords/temperature-effects","display_name":"temperature effects","score":0.640999972820282},{"id":"https://openalex.org/keywords/hydrogel-lenses","display_name":"hydrogel lenses","score":0.6690000295639038},{"id":"https://openalex.org/keywords/silicone-hydrogel-contact-lenses","display_name":"silicone hydrogel contact lenses","score":0.9980000257492065},{"id":"https://openalex.org/keywords/ketotifen-fumarate","display_name":"ketotifen fumarate","score":0.9390000104904175},{"id":"https://openalex.org/keywords/diclofenac-sodium","display_name":"diclofenac sodium","score":0.9980000257492065},{"id":"https://openalex.org/keywords/timolol-maleate","display_name":"timolol maleate","score":0.9990000128746033},{"id":"https://openalex.org/keywords/dexamethasone","display_name":"dexamethasone","score":0.9829999804496765},{"id":"https://openalex.org/keywords/hydrophilic-and-hydrophobic-drugs","display_name":"hydrophilic and hydrophobic drugs","score":0.8289999961853027}],"concepts":[{"id":"https://openalex.org/C118487528","wikidata":"https://www.wikidata.org/wiki/Q161437","display_name":"Ophthalmology","level":1,"score":0.5320953130722046},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.45037615299224854},{"id":"https://openalex.org/C9652623","wikidata":"https://www.wikidata.org/wiki/Q190109","display_name":"Field (mathematics)","level":2,"score":0.4198862910270691},{"id":"https://openalex.org/C119767625","wikidata":"https://www.wikidata.org/wiki/Q618211","display_name":"Optometry","level":1,"score":0.3626854419708252},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.0826447606086731},{"id":"https://openalex.org/C202444582","wikidata":"https://www.wikidata.org/wiki/Q837863","display_name":"Pure mathematics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D003263","descriptor_name":"Contact Lenses, Hydrophilic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004058","descriptor_name":"Diffusion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004343","descriptor_name":"Drug Implants","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D004867","descriptor_name":"Equipment Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007700","descriptor_name":"Kinetics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008422","descriptor_name":"Materials Testing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009883","descriptor_name":"Ophthalmic Solutions","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D009883","descriptor_name":"Ophthalmic Solutions","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D019544","descriptor_name":"Equipment Failure Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D065966","descriptor_name":"Absorption, Physicochemical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.clae.2014.04.005","doi":"https://doi.org/10.1016/j.clae.2014.04.005","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.clae.2014.04.005","pdf_url":null,"source":{"id":"https://openalex.org/S137552098","display_name":"Contact Lens and Anterior Eye","issn_l":"1367-0484","issn":["1367-0484","1476-5411"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Contact Lens and Anterior Eye","raw_type":"journal-article"},{"id":"pmid:24894544","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24894544","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Contact lens & anterior eye : the journal of the British Contact Lens Association","raw_type":"Comparative Study"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.8560000061988831,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":36,"referenced_works":["https://openalex.org/W46341933","https://openalex.org/W334539524","https://openalex.org/W646544898","https://openalex.org/W1935413599","https://openalex.org/W1968121289","https://openalex.org/W1976708907","https://openalex.org/W1978285976","https://openalex.org/W1983164716","https://openalex.org/W1986180285","https://openalex.org/W1993458332","https://openalex.org/W2001872244","https://openalex.org/W2007185684","https://openalex.org/W2010015245","https://openalex.org/W2013242195","https://openalex.org/W2014979579","https://openalex.org/W2025405975","https://openalex.org/W2041930305","https://openalex.org/W2045522408","https://openalex.org/W2052218830","https://openalex.org/W2062250261","https://openalex.org/W2065741669","https://openalex.org/W2068908796","https://openalex.org/W2070318887","https://openalex.org/W2072399777","https://openalex.org/W2073617358","https://openalex.org/W2077400553","https://openalex.org/W2079141522","https://openalex.org/W2079288041","https://openalex.org/W2084646167","https://openalex.org/W2086803160","https://openalex.org/W2094822768","https://openalex.org/W2096730562","https://openalex.org/W2109077016","https://openalex.org/W2127765589","https://openalex.org/W2153580666","https://openalex.org/W2842556333"],"related_works":["https://openalex.org/W2278798322","https://openalex.org/W6995393817","https://openalex.org/W2335367051","https://openalex.org/W2068908796","https://openalex.org/W2196844599","https://openalex.org/W1996769776","https://openalex.org/W4416332184","https://openalex.org/W2471941743","https://openalex.org/W2014979579","https://openalex.org/W2090011974"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":5},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":6},{"year":2020,"cited_by_count":5},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":7},{"year":2017,"cited_by_count":6},{"year":2016,"cited_by_count":5},{"year":2015,"cited_by_count":5},{"year":2014,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}