{"id":"https://openalex.org/W2102895446","doi":"https://doi.org/10.1097/01.cji.0000188502.11348.34","title":"Cellular and Humoral Immune Response to N-Glycolyl-GM3 Elicited by Prolonged Immunotherapy With an Anti-Idiotypic Vaccine in High-Risk and Metastatic Breast Cancer Patients","display_name":"Cellular and Humoral Immune Response to N-Glycolyl-GM3 Elicited by Prolonged Immunotherapy With an Anti-Idiotypic Vaccine in High-Risk and Metastatic Breast Cancer Patients","publication_year":2006,"publication_date":"2006-03-01","ids":{"openalex":"https://openalex.org/W2102895446","doi":"https://doi.org/10.1097/01.cji.0000188502.11348.34","mag":"2102895446","pmid":"https://pubmed.ncbi.nlm.nih.gov/16531822"},"language":"en","primary_location":{"id":"doi:10.1097/01.cji.0000188502.11348.34","doi":"https://doi.org/10.1097/01.cji.0000188502.11348.34","is_oa":false,"landing_page_url":"https://doi.org/10.1097/01.cji.0000188502.11348.34","pdf_url":null,"source":{"id":"https://openalex.org/S177451610","display_name":"Journal of Immunotherapy","issn_l":"1524-9557","issn":["1524-9557","1537-4513"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Immunotherapy","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://hdl.handle.net/11336/116261","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5026120252","display_name":"Marcelo D. Guthmann","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I24354313","display_name":"Universidad de Buenos Aires","ror":"https://ror.org/0081fs513","country_code":"AR","type":"education","lineage":["https://openalex.org/I24354313"]},{"id":"https://openalex.org/I4210119967","display_name":"Hospital de Cl\u00ednicas \"Jos\u00e9 de San Mart\u00edn\"","ror":"https://ror.org/02hbrab76","country_code":"AR","type":"healthcare","lineage":["https://openalex.org/I4210119967"]}],"countries":["AR"],"is_corresponding":true,"raw_author_name":"Marcelo D. Guthmann","raw_affiliation_strings":["Hospital de Cl\u00ednicas Jos\u00e9 de San Mart\u00edn, University of Buenos Aires, Buenos Aires, Argentina. ruculeufu@arnet.com.ar","Hospital de Cl\u00ednicas Jos\u00e9 de San Mart\u00edn, University of Buenos Aires, Buenos Aires, Argentina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hospital de Cl\u00ednicas Jos\u00e9 de San Mart\u00edn, University of Buenos Aires, Buenos Aires, Argentina. ruculeufu@arnet.com.ar","institution_ids":["https://openalex.org/I24354313","https://openalex.org/I4210119967"]},{"raw_affiliation_string":"Hospital de Cl\u00ednicas Jos\u00e9 de San Mart\u00edn, University of Buenos Aires, Buenos Aires, Argentina","institution_ids":["https://openalex.org/I24354313","https://openalex.org/I4210119967"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101576207","display_name":"Monica A. Castro","orcid":"https://orcid.org/0000-0002-1907-999X","observed_orcids":["https://orcid.org/0000-0002-1907-999X"]},"institutions":[{"id":"https://openalex.org/I24354313","display_name":"Universidad de Buenos Aires","ror":"https://ror.org/0081fs513","country_code":"AR","type":"education","lineage":["https://openalex.org/I24354313"]},{"id":"https://openalex.org/I4210119967","display_name":"Hospital de Cl\u00ednicas \"Jos\u00e9 de San Mart\u00edn\"","ror":"https://ror.org/02hbrab76","country_code":"AR","type":"healthcare","lineage":["https://openalex.org/I4210119967"]}],"countries":["AR"],"is_corresponding":true,"raw_author_name":"M\u00f3nica A. Castro","raw_affiliation_strings":["Hospital de Cl\u00ednicas Jos\u00e9 de San Mart\u00edn, University of Buenos Aires, Buenos Aires, Argentina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hospital de Cl\u00ednicas Jos\u00e9 de San Mart\u00edn, University of Buenos Aires, Buenos Aires, Argentina","institution_ids":["https://openalex.org/I24354313","https://openalex.org/I4210119967"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016168877","display_name":"Gabriela Cinat","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I24354313","display_name":"Universidad de Buenos Aires","ror":"https://ror.org/0081fs513","country_code":"AR","type":"education","lineage":["https://openalex.org/I24354313"]}],"countries":["AR"],"is_corresponding":false,"raw_author_name":"Gabriela Cinat","raw_affiliation_strings":["Instituto de Oncolog\u00eda \u00c1ngel Roffo, University of Buenos Aires, Buenos Aires, Argentina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Instituto de Oncolog\u00eda \u00c1ngel Roffo, University of Buenos Aires, Buenos Aires, Argentina","institution_ids":["https://openalex.org/I24354313"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113712805","display_name":"Cecilia Venier","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I24354313","display_name":"Universidad de Buenos Aires","ror":"https://ror.org/0081fs513","country_code":"AR","type":"education","lineage":["https://openalex.org/I24354313"]},{"id":"https://openalex.org/I4210119967","display_name":"Hospital de Cl\u00ednicas \"Jos\u00e9 de San Mart\u00edn\"","ror":"https://ror.org/02hbrab76","country_code":"AR","type":"healthcare","lineage":["https://openalex.org/I4210119967"]}],"countries":["AR"],"is_corresponding":true,"raw_author_name":"Cecilia Venier","raw_affiliation_strings":["Hospital de Cl\u00ednicas Jos\u00e9 de San Mart\u00edn, University of Buenos Aires, Buenos Aires, Argentina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hospital de Cl\u00ednicas Jos\u00e9 de San Mart\u00edn, University of Buenos Aires, Buenos Aires, Argentina","institution_ids":["https://openalex.org/I24354313","https://openalex.org/I4210119967"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088825862","display_name":"Leonardo Koliren","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2990283872","display_name":"El Hospital General de Agudos Carlos G. Durand","ror":"https://ror.org/03w11wq45","country_code":"AR","type":"healthcare","lineage":["https://openalex.org/I2990283872"]}],"countries":["AR"],"is_corresponding":false,"raw_author_name":"Leonardo Koliren","raw_affiliation_strings":["Hospital Dr. Carlos G. Durand, Buenos Aires, Argentina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hospital Dr. Carlos G. Durand, Buenos Aires, Argentina","institution_ids":["https://openalex.org/I2990283872"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007407637","display_name":"Roberto Jorge Bitton","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I24354313","display_name":"Universidad de Buenos Aires","ror":"https://ror.org/0081fs513","country_code":"AR","type":"education","lineage":["https://openalex.org/I24354313"]},{"id":"https://openalex.org/I4210119967","display_name":"Hospital de Cl\u00ednicas \"Jos\u00e9 de San Mart\u00edn\"","ror":"https://ror.org/02hbrab76","country_code":"AR","type":"healthcare","lineage":["https://openalex.org/I4210119967"]}],"countries":["AR"],"is_corresponding":true,"raw_author_name":"Roberto J. Bitton","raw_affiliation_strings":["Hospital de Cl\u00ednicas Jos\u00e9 de San Mart\u00edn, University of Buenos Aires, Buenos Aires, Argentina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hospital de Cl\u00ednicas Jos\u00e9 de San Mart\u00edn, University of Buenos Aires, Buenos Aires, Argentina","institution_ids":["https://openalex.org/I24354313","https://openalex.org/I4210119967"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101936588","display_name":"Ana Mar\u00eda V\u00e1zquez","orcid":"https://orcid.org/0000-0003-1265-5066","observed_orcids":["https://orcid.org/0000-0003-1265-5066"]},"institutions":[{"id":"https://openalex.org/I2355400","display_name":"Center of Molecular Immunology (Cuba)","ror":"https://ror.org/01gh7yb82","country_code":"CU","type":"company","lineage":["https://openalex.org/I2355400"]}],"countries":["CU"],"is_corresponding":false,"raw_author_name":"Ana Mar\u00eda V\u00e1zquez","raw_affiliation_strings":["Center of Molecular Immunology, Havana, Cuba"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center of Molecular Immunology, Havana, Cuba","institution_ids":["https://openalex.org/I2355400"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5037055171","display_name":"Leonardo Fainboim","orcid":"https://orcid.org/0000-0002-8907-0341","observed_orcids":["https://orcid.org/0000-0002-8907-0341"]},"institutions":[{"id":"https://openalex.org/I24354313","display_name":"Universidad de Buenos Aires","ror":"https://ror.org/0081fs513","country_code":"AR","type":"education","lineage":["https://openalex.org/I24354313"]},{"id":"https://openalex.org/I4210119967","display_name":"Hospital de Cl\u00ednicas \"Jos\u00e9 de San Mart\u00edn\"","ror":"https://ror.org/02hbrab76","country_code":"AR","type":"healthcare","lineage":["https://openalex.org/I4210119967"]}],"countries":["AR"],"is_corresponding":true,"raw_author_name":"Leonardo Fainboim","raw_affiliation_strings":["Hospital de Cl\u00ednicas Jos\u00e9 de San Mart\u00edn, University of Buenos Aires, Buenos Aires, Argentina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hospital de Cl\u00ednicas Jos\u00e9 de San Mart\u00edn, University of Buenos Aires, Buenos Aires, Argentina","institution_ids":["https://openalex.org/I24354313","https://openalex.org/I4210119967"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5007407637","https://openalex.org/A5026120252","https://openalex.org/A5037055171","https://openalex.org/A5101576207","https://openalex.org/A5113712805"],"corresponding_institution_ids":["https://openalex.org/I24354313","https://openalex.org/I4210119967"],"apc_list":null,"apc_paid":null,"fwci":2.1613,"has_fulltext":false,"cited_by_count":60,"citation_normalized_percentile":{"value":0.87505243,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":99},"biblio":{"volume":"29","issue":"2","first_page":"215","last_page":"223"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10580","display_name":"Immunotherapy and Immune Responses","score":0.986299991607666,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10580","display_name":"Immunotherapy and Immune Responses","score":0.986299991607666,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10602","display_name":"Glycosylation and Glycoproteins Research","score":0.008200000040233135,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10835","display_name":"Carbohydrate Chemistry and Synthesis","score":0.0012000000569969416,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/metastatic-breast-cancer","display_name":"metastatic breast cancer","score":0.9480000138282776},{"id":"https://openalex.org/keywords/high-risk-breast-cancer","display_name":"high-risk breast cancer","score":0.9150000214576721},{"id":"https://openalex.org/keywords/humoral-immune-response","display_name":"humoral immune response","score":0.8790000081062317},{"id":"https://openalex.org/keywords/vaccine-immunogenicity","display_name":"vaccine immunogenicity","score":0.9120000004768372},{"id":"https://openalex.org/keywords/vaccine-toxicity","display_name":"vaccine toxicity","score":0.8840000033378601},{"id":"https://openalex.org/keywords/dose-escalation","display_name":"dose escalation","score":0.6100000143051147},{"id":"https://openalex.org/keywords/intradermal-vaccination","display_name":"intradermal vaccination","score":0.8230000138282776},{"id":"https://openalex.org/keywords/vaccine-hypersensitivity","display_name":"vaccine hypersensitivity","score":0.5490000247955322}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8744766712188721},{"id":"https://openalex.org/C2780868878","wikidata":"https://www.wikidata.org/wiki/Q1660197","display_name":"Immunogenicity","level":3,"score":0.7176946401596069},{"id":"https://openalex.org/C197934379","wikidata":"https://www.wikidata.org/wiki/Q2047938","display_name":"Adverse effect","level":2,"score":0.7113010883331299},{"id":"https://openalex.org/C22070199","wikidata":"https://www.wikidata.org/wiki/Q192995","display_name":"Vaccination","level":2,"score":0.6261373162269592},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.6025682687759399},{"id":"https://openalex.org/C2777701055","wikidata":"https://www.wikidata.org/wiki/Q1427096","display_name":"Immunotherapy","level":3,"score":0.6023640632629395},{"id":"https://openalex.org/C2777331542","wikidata":"https://www.wikidata.org/wiki/Q419287","display_name":"Ganglioside","level":2,"score":0.5686221718788147},{"id":"https://openalex.org/C29730261","wikidata":"https://www.wikidata.org/wiki/Q274160","display_name":"Toxicity","level":2,"score":0.5255521535873413},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.49268585443496704},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.4911606013774872},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.48018160462379456},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.41052088141441345},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.40922218561172485},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.3627970218658447},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005679","descriptor_name":"G(M3) Ganglioside","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":true},{"descriptor_ui":"D005679","descriptor_name":"G(M3) Ganglioside","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007130","descriptor_name":"Immunoglobulin Idiotypes","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D007167","descriptor_name":"Immunotherapy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009362","descriptor_name":"Neoplasm Metastasis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014611","descriptor_name":"Vaccination","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019496","descriptor_name":"Cancer Vaccines","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D019496","descriptor_name":"Cancer Vaccines","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D019496","descriptor_name":"Cancer Vaccines","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1097/01.cji.0000188502.11348.34","doi":"https://doi.org/10.1097/01.cji.0000188502.11348.34","is_oa":false,"landing_page_url":"https://doi.org/10.1097/01.cji.0000188502.11348.34","pdf_url":null,"source":{"id":"https://openalex.org/S177451610","display_name":"Journal of Immunotherapy","issn_l":"1524-9557","issn":["1524-9557","1537-4513"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Immunotherapy","raw_type":"journal-article"},{"id":"pmid:16531822","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16531822","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of immunotherapy (Hagerstown, Md. : 1997)","raw_type":"Clinical Trial, Phase I"},{"id":"pmh:oai:ri.conicet.gov.ar:11336/116261","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/11336/116261","pdf_url":null,"source":{"id":"https://openalex.org/S4306402455","display_name":"CONICET Digital (CONICET)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210148385","host_organization_name":"Biomedicine Research Institute of Buenos Aires - CONICET - Partner Institute of the Max Planck Society","host_organization_lineage":["https://openalex.org/I4210148385"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"pmh:oai:ri.conicet.gov.ar:11336/116261","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/11336/116261","pdf_url":null,"source":{"id":"https://openalex.org/S4306402455","display_name":"CONICET Digital (CONICET)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210148385","host_organization_name":"Biomedicine Research Institute of Buenos Aires - CONICET - Partner Institute of the Max Planck Society","host_organization_lineage":["https://openalex.org/I4210148385"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"},"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Clinical Trial","id":"https://openalex.org/study-designs/clinical-trial"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":45,"referenced_works":["https://openalex.org/W119929283","https://openalex.org/W206480088","https://openalex.org/W1488880613","https://openalex.org/W1549614329","https://openalex.org/W1590736370","https://openalex.org/W1801816242","https://openalex.org/W1866549327","https://openalex.org/W1966719737","https://openalex.org/W1972085567","https://openalex.org/W1978047433","https://openalex.org/W1978282886","https://openalex.org/W1997275703","https://openalex.org/W1998547530","https://openalex.org/W2001281410","https://openalex.org/W2016869494","https://openalex.org/W2027442953","https://openalex.org/W2034018980","https://openalex.org/W2035446451","https://openalex.org/W2036196494","https://openalex.org/W2036387778","https://openalex.org/W2038862452","https://openalex.org/W2049304938","https://openalex.org/W2052817467","https://openalex.org/W2059529313","https://openalex.org/W2061778218","https://openalex.org/W2067844377","https://openalex.org/W2068920805","https://openalex.org/W2075926115","https://openalex.org/W2095549072","https://openalex.org/W2104948886","https://openalex.org/W2109043551","https://openalex.org/W2115951816","https://openalex.org/W2116075163","https://openalex.org/W2121143384","https://openalex.org/W2129268236","https://openalex.org/W2141179819","https://openalex.org/W2158601669","https://openalex.org/W2159548595","https://openalex.org/W2162438783","https://openalex.org/W2239046105","https://openalex.org/W2414165847","https://openalex.org/W4243603314","https://openalex.org/W6635401701","https://openalex.org/W6683462218","https://openalex.org/W6683770717"],"related_works":["https://openalex.org/W2249564639","https://openalex.org/W2035446451","https://openalex.org/W2129268236","https://openalex.org/W2024630287","https://openalex.org/W2141179819","https://openalex.org/W4313351427","https://openalex.org/W2049729316","https://openalex.org/W2624157050","https://openalex.org/W2002581939","https://openalex.org/W2116075163"],"abstract_inverted_index":{"In":[0,157],"this":[1],"study,":[2],"the":[3,14,73,82,88,119,132,144,154,185,190],"immunogenicity":[4],"and":[5,62,67,72,80,101,175],"toxicity":[6],"profile":[7],"of":[8,29,58,122,138,166],"1E10,":[9],"an":[10,20],"anti-idiotypic":[11],"vaccine":[12],"mimicking":[13],"N-glycolyl-GM3":[15],"ganglioside,":[16],"was":[17,129,173,194],"investigated":[18],"with":[19,44,54,140,171,184],"extended":[21],"vaccination":[22,26],"protocol.":[23],"The":[24,65],"year-long":[25],"scheme":[27],"consisted":[28],"6":[30],"biweekly":[31],"intradermal":[32],"injections":[33],"(induction":[34],"phase),":[35],"followed":[36,103],"by":[37,104],"10":[38],"monthly":[39],"boosters":[40],"(maintenance).":[41],"Nineteen":[42],"patients":[43,115,147],"high-risk":[45],"(stage":[46],"III)":[47],"or":[48],"metastatic":[49],"breast":[50],"cancer":[51],"were":[52,76,116,162,182],"vaccinated":[53],"different":[55],"dose":[56,188,192],"levels":[57],"1E10":[59,71,172],"(0.5,":[60],"1,":[61],"2":[63,112],"mg).":[64],"humoral":[66],"cellular":[68],"responses":[69,161],"to":[70,111,143,153],"targeted":[74,155],"ganglioside":[75],"assessed":[77],"at":[78],"baseline":[79],"throughout":[81],"treatment.":[83],"Local":[84],"skin":[85],"reactions":[86],"represented":[87],"most":[89],"common":[90],"adverse":[91],"event":[92],"(National":[93],"Cancer":[94],"Institute":[95],"Toxicity":[96],"Criteria":[97],"(NCIC)":[98],"grades":[99],"I":[100],"II),":[102],"mild":[105],"flu-like":[106],"symptoms":[107],"lasting":[108],"for":[109,196],"1":[110],"days.":[113],"Two":[114],"removed":[117,130],"from":[118,131],"study":[120,133],"because":[121],"vaccine-related":[123],"hypersensitivity":[124],"reactions.":[125],"A":[126],"third":[127],"patient":[128],"after":[134],"a":[135,149],"transient":[136],"loss":[137],"consciousness":[139],"uncertain":[141],"relation":[142],"vaccine.":[145],"All":[146],"showed":[148],"strong":[150],"antibody":[151],"response":[152],"ganglioside.":[156],"addition,":[158],"ganglioside-specific":[159],"T-cell":[160],"recorded":[163],"in":[164],"5":[165],"13":[167],"evaluable":[168],"patients.":[169],"Vaccination":[170],"immunogenic":[174],"relatively":[176],"well":[177],"tolerated.":[178],"Because":[179],"similar":[180],"results":[181],"observed":[183],"3":[186],"tested":[187],"levels,":[189],"0.5-mg":[191],"level":[193],"selected":[195],"future":[197],"trials.":[198]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2016,"cited_by_count":4},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":8},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":6}],"updated_date":"2026-11-05T12:25:35.769452","created_date":"2016-06-24T00:00:00"}