{"id":"https://openalex.org/W2102563366","doi":"https://doi.org/10.1007/s10753-012-9544-4","title":"Association of Rheumatoid Arthritis Risk Alleles with Response to Anti-TNF Biologics: Results from the CORRONA Registry and Meta-analysis","display_name":"Association of Rheumatoid Arthritis Risk Alleles with Response to Anti-TNF Biologics: Results from the CORRONA Registry and Meta-analysis","publication_year":2012,"publication_date":"2012-09-24","ids":{"openalex":"https://openalex.org/W2102563366","doi":"https://doi.org/10.1007/s10753-012-9544-4","mag":"2102563366","pmid":"https://pubmed.ncbi.nlm.nih.gov/23007924"},"language":"en","primary_location":{"id":"doi:10.1007/s10753-012-9544-4","doi":"https://doi.org/10.1007/s10753-012-9544-4","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s10753-012-9544-4","pdf_url":null,"source":{"id":"https://openalex.org/S127393932","display_name":"Inflammation","issn_l":"0360-3997","issn":["0360-3997","1573-2576"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Inflammation","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5049960008","display_name":"Dimitrios A. Pappas","orcid":"https://orcid.org/0000-0001-8338-027X","observed_orcids":["https://orcid.org/0000-0001-8338-027X"]},"institutions":[{"id":"https://openalex.org/I1340179700","display_name":"NewYork\u2013Presbyterian Hospital","ror":"https://ror.org/03gzbrs57","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1340179700"]},{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Dimitrios A. Pappas","raw_affiliation_strings":["Division of Rheumatology, Department of Medicine, New York Presbyterian Hospital, College of Physicians and Surgeons, Columbia University, P&S Building, Suite 10-455, New York, NY 10032, USA. dp2544@columbia.edu","Division of Rheumatology, Department of Medicine, New York, Presbyterian Hospital, College of Physicians and Surgeons, Columbia University, New York, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Rheumatology, Department of Medicine, New York Presbyterian Hospital, College of Physicians and Surgeons, Columbia University, P&S Building, Suite 10-455, New York, NY 10032, USA. dp2544@columbia.edu","institution_ids":["https://openalex.org/I1340179700","https://openalex.org/I78577930"]},{"raw_affiliation_string":"Division of Rheumatology, Department of Medicine, New York, Presbyterian Hospital, College of Physicians and Surgeons, Columbia University, New York, USA","institution_ids":["https://openalex.org/I1340179700","https://openalex.org/I78577930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062484027","display_name":"Cheongeun Oh","orcid":"https://orcid.org/0000-0001-8907-0985","observed_orcids":["https://orcid.org/0000-0001-8907-0985","https://orcid.org/0009-0005-7688-0395"]},"institutions":[{"id":"https://openalex.org/I57206974","display_name":"New York University","ror":"https://ror.org/0190ak572","country_code":"US","type":"education","lineage":["https://openalex.org/I57206974"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Cheongeun Oh","raw_affiliation_strings":["Biostatistics, Department of Population Health, New York University School of Medicine, 650 First Avenue, #556, New York, NY, 10016, USA","Biostatistics, Department of Population Health, New York University School of Medicine, New York, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biostatistics, Department of Population Health, New York University School of Medicine, 650 First Avenue, #556, New York, NY, 10016, USA","institution_ids":["https://openalex.org/I57206974"]},{"raw_affiliation_string":"Biostatistics, Department of Population Health, New York University School of Medicine, New York, USA","institution_ids":["https://openalex.org/I57206974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5106486411","display_name":"Robert M. Plenge","orcid":"https://orcid.org/0000-0002-3705-5924","observed_orcids":["https://orcid.org/0000-0002-3705-5924"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert M. Plenge","raw_affiliation_strings":["Division of Rheumatology, Immunology and Allergy, Harvard Medical School, New Research Building (NRB), 77 Avenue Louis Pasteur, Boston, MA, 02115, USA","Division of Rheumatology, Immunology and Allergy, Harvard Medical School, Boston, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Rheumatology, Immunology and Allergy, Harvard Medical School, New Research Building (NRB), 77 Avenue Louis Pasteur, Boston, MA, 02115, USA","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"Division of Rheumatology, Immunology and Allergy, Harvard Medical School, Boston, USA","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014147030","display_name":"Joel M. Kremer","orcid":"https://orcid.org/0000-0001-6674-9901","observed_orcids":["https://orcid.org/0000-0001-6674-9901"]},"institutions":[{"id":"https://openalex.org/I4210159453","display_name":"Center for Rheumatology","ror":"https://ror.org/04rtaxr13","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210159453"]},{"id":"https://openalex.org/I77920804","display_name":"Albany Medical Center Hospital","ror":"https://ror.org/0307crw42","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4405259726","https://openalex.org/I77920804"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Joel M. Kremer","raw_affiliation_strings":["Department of Medicine, Albany Medical Center and The Center for Rheumatology, 1367 Washington Ave Ste 101, Albany, NY, 12206, USA","Department of Medicine, Albany Medical Center and The Center for Rheumatology, Albany, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Albany Medical Center and The Center for Rheumatology, 1367 Washington Ave Ste 101, Albany, NY, 12206, USA","institution_ids":["https://openalex.org/I4210159453","https://openalex.org/I77920804"]},{"raw_affiliation_string":"Department of Medicine, Albany Medical Center and The Center for Rheumatology, Albany, USA","institution_ids":["https://openalex.org/I4210159453","https://openalex.org/I77920804"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5030768494","display_name":"Jeffrey D. Greenberg","orcid":"https://orcid.org/0000-0001-9711-0457","observed_orcids":["https://orcid.org/0000-0001-9711-0457"]},"institutions":[{"id":"https://openalex.org/I4210163050","display_name":"New York University Langone Orthopedic Hospital","ror":"https://ror.org/05d789537","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210086933","https://openalex.org/I4210163050"]},{"id":"https://openalex.org/I57206974","display_name":"New York University","ror":"https://ror.org/0190ak572","country_code":"US","type":"education","lineage":["https://openalex.org/I57206974"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jeffrey D. Greenberg","raw_affiliation_strings":["Department of Rheumatology, New York University Hospital for Joint Diseases, 301 East 17th Street, Suite 1410, New York, NY, 10003, USA","Department of Rheumatology, New York University Hospital for Joint Diseases, New York, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Rheumatology, New York University Hospital for Joint Diseases, 301 East 17th Street, Suite 1410, New York, NY, 10003, USA","institution_ids":["https://openalex.org/I4210163050","https://openalex.org/I57206974"]},{"raw_affiliation_string":"Department of Rheumatology, New York University Hospital for Joint Diseases, New York, USA","institution_ids":["https://openalex.org/I4210163050","https://openalex.org/I57206974"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5049960008"],"corresponding_institution_ids":["https://openalex.org/I1340179700","https://openalex.org/I78577930"],"apc_list":{"value":4790,"currency":"USD","value_usd":4790},"apc_paid":null,"fwci":1.2239,"has_fulltext":false,"cited_by_count":18,"citation_normalized_percentile":{"value":0.79454702,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"36","issue":"2","first_page":"279","last_page":"284"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10200","display_name":"Rheumatoid Arthritis Research and Therapies","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10200","display_name":"Rheumatoid Arthritis Research and Therapies","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11616","display_name":"Autoimmune and Inflammatory Disorders Research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/rheumatoid-arthritis","display_name":"rheumatoid arthritis","score":1.0},{"id":"https://openalex.org/keywords/anti-tnf-biologics","display_name":"anti-TNF biologics","score":0.9660000205039978},{"id":"https://openalex.org/keywords/treatment-response","display_name":"treatment response","score":0.7419999837875366},{"id":"https://openalex.org/keywords/single-nucleotide-polymorphisms","display_name":"single nucleotide polymorphisms","score":0.9869999885559082},{"id":"https://openalex.org/keywords/cd28","display_name":"CD28","score":0.953000009059906},{"id":"https://openalex.org/keywords/ccl21","display_name":"CCL21","score":0.9900000095367432},{"id":"https://openalex.org/keywords/disease-activity","display_name":"disease activity","score":0.7409999966621399},{"id":"https://openalex.org/keywords/das28","display_name":"DAS28","score":0.949999988079071},{"id":"https://openalex.org/keywords/methotrexate","display_name":"methotrexate","score":0.8759999871253967},{"id":"https://openalex.org/keywords/corrona-registry","display_name":"Corrona registry","score":0.8349999785423279}],"concepts":[{"id":"https://openalex.org/C2777575956","wikidata":"https://www.wikidata.org/wiki/Q187255","display_name":"Rheumatoid arthritis","level":2,"score":0.7553138732910156},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.7290313243865967},{"id":"https://openalex.org/C153209595","wikidata":"https://www.wikidata.org/wiki/Q501128","display_name":"Single-nucleotide polymorphism","level":4,"score":0.6898584365844727},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6325218081474304},{"id":"https://openalex.org/C139275648","wikidata":"https://www.wikidata.org/wiki/Q17134011","display_name":"SNP","level":5,"score":0.6148216128349304},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.576111376285553},{"id":"https://openalex.org/C198451711","wikidata":"https://www.wikidata.org/wiki/Q327657","display_name":"Rheumatology","level":2,"score":0.5528752207756042},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.49039697647094727},{"id":"https://openalex.org/C180754005","wikidata":"https://www.wikidata.org/wiki/Q80726","display_name":"Allele","level":3,"score":0.41420748829841614},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.358595609664917},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.22103363275527954},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.2050994634628296},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.18076935410499573},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.11714497208595276}],"mesh":[{"descriptor_ui":"D001172","descriptor_name":"Arthritis, Rheumatoid","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005838","descriptor_name":"Genotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008137","descriptor_name":"Longitudinal Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012306","descriptor_name":"Risk","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014409","descriptor_name":"Tumor Necrosis Factor-alpha","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":true},{"descriptor_ui":"D014644","descriptor_name":"Genetic Variation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015331","descriptor_name":"Cohort Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018106","descriptor_name":"CD28 Antigens","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D018501","descriptor_name":"Antirheumatic Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D020022","descriptor_name":"Genetic Predisposition to Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020641","descriptor_name":"Polymorphism, Single Nucleotide","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D054421","descriptor_name":"Chemokine CCL21","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1007/s10753-012-9544-4","doi":"https://doi.org/10.1007/s10753-012-9544-4","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s10753-012-9544-4","pdf_url":null,"source":{"id":"https://openalex.org/S127393932","display_name":"Inflammation","issn_l":"0360-3997","issn":["0360-3997","1573-2576"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Inflammation","raw_type":"journal-article"},{"id":"pmid:23007924","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23007924","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Inflammation","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9907000064849854}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":13,"referenced_works":["https://openalex.org/W1994679397","https://openalex.org/W2020413892","https://openalex.org/W2035036601","https://openalex.org/W2052564007","https://openalex.org/W2064015154","https://openalex.org/W2086478005","https://openalex.org/W2098896429","https://openalex.org/W2115783720","https://openalex.org/W2118831603","https://openalex.org/W2126718294","https://openalex.org/W2160768927","https://openalex.org/W2263228148","https://openalex.org/W4211019157"],"related_works":["https://openalex.org/W2118831603","https://openalex.org/W2057258114","https://openalex.org/W2160768927","https://openalex.org/W2127106391","https://openalex.org/W2073800064","https://openalex.org/W2412066917","https://openalex.org/W4253456999","https://openalex.org/W4320034667","https://openalex.org/W2170984667","https://openalex.org/W2163320038"],"abstract_inverted_index":null,"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":4},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}