{"id":"https://openalex.org/W2102392334","doi":"https://doi.org/10.1038/nm727","title":"Inhibition of gastric inhibitory polypeptide signaling prevents obesity","display_name":"Inhibition of gastric inhibitory polypeptide signaling prevents obesity","publication_year":2002,"publication_date":"2002-06-17","ids":{"openalex":"https://openalex.org/W2102392334","doi":"https://doi.org/10.1038/nm727","mag":"2102392334","pmid":"https://pubmed.ncbi.nlm.nih.gov/12068290"},"language":"en","primary_location":{"id":"doi:10.1038/nm727","doi":"https://doi.org/10.1038/nm727","is_oa":false,"landing_page_url":"https://doi.org/10.1038/nm727","pdf_url":null,"source":{"id":"https://openalex.org/S203256638","display_name":"Nature Medicine","issn_l":"1078-8956","issn":["1078-8956","1546-170X","1744-7933"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Medicine","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5075963286","display_name":"Kazumasa Miyawaki","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kazumasa Miyawaki","raw_affiliation_strings":["Department of Diabetes and Clinical Nutrition, Graduate School of Medicine, Kyoto University, Kyoto, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Diabetes and Clinical Nutrition, Graduate School of Medicine, Kyoto University, Kyoto, Japan","institution_ids":["https://openalex.org/I22299242"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101701620","display_name":"Yuichiro Yamada","orcid":"https://orcid.org/0000-0003-1623-0815","observed_orcids":["https://orcid.org/0000-0003-1623-0815","https://orcid.org/0009-0007-5430-9870"]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yuichiro Yamada","raw_affiliation_strings":["Department of Diabetes and Clinical Nutrition, Graduate School of Medicine, Kyoto University, Kyoto, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Diabetes and Clinical Nutrition, Graduate School of Medicine, Kyoto University, Kyoto, Japan","institution_ids":["https://openalex.org/I22299242"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033863405","display_name":"Nobuhiro Ban","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Nobuhiro Ban","raw_affiliation_strings":["Department of Diabetes and Clinical Nutrition, Graduate School of Medicine, Kyoto University, Kyoto, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Diabetes and Clinical Nutrition, Graduate School of Medicine, Kyoto University, Kyoto, Japan","institution_ids":["https://openalex.org/I22299242"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111626025","display_name":"Yu Ihara","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yu Ihara","raw_affiliation_strings":["Department of Diabetes and Clinical Nutrition, Graduate School of Medicine, Kyoto University, Kyoto, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Diabetes and Clinical Nutrition, Graduate School of Medicine, Kyoto University, Kyoto, Japan","institution_ids":["https://openalex.org/I22299242"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009374010","display_name":"Katsushi Tsukiyama","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Katsushi Tsukiyama","raw_affiliation_strings":["Department of Diabetes and Clinical Nutrition, Graduate School of Medicine, Kyoto University, Kyoto, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Diabetes and Clinical Nutrition, Graduate School of Medicine, Kyoto University, Kyoto, Japan","institution_ids":["https://openalex.org/I22299242"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000564310","display_name":"Heying Zhou","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Heying Zhou","raw_affiliation_strings":["Department of Diabetes and Clinical Nutrition, Graduate School of Medicine, Kyoto University, Kyoto, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Diabetes and Clinical Nutrition, Graduate School of Medicine, Kyoto University, Kyoto, Japan","institution_ids":["https://openalex.org/I22299242"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043503909","display_name":"Shimpei Fujimoto","orcid":"https://orcid.org/0000-0001-9413-0831","observed_orcids":["https://orcid.org/0000-0001-9413-0831"]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Shimpei Fujimoto","raw_affiliation_strings":["Department of Diabetes and Clinical Nutrition, Graduate School of Medicine, Kyoto University, Kyoto, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Diabetes and Clinical Nutrition, Graduate School of Medicine, Kyoto University, Kyoto, Japan","institution_ids":["https://openalex.org/I22299242"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109142048","display_name":"Akira Oku","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Akira Oku","raw_affiliation_strings":["Department of Diabetes and Clinical Nutrition, Graduate School of Medicine, Kyoto University, Kyoto, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Diabetes and Clinical Nutrition, Graduate School of Medicine, Kyoto University, Kyoto, Japan","institution_ids":["https://openalex.org/I22299242"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103501804","display_name":"Kinsuke Tsuda","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kinsuke Tsuda","raw_affiliation_strings":["Department of Diabetes and Clinical Nutrition, Graduate School of Medicine, Kyoto University, Kyoto, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Diabetes and Clinical Nutrition, Graduate School of Medicine, Kyoto University, Kyoto, Japan","institution_ids":["https://openalex.org/I22299242"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069594191","display_name":"Shinya Toyokuni","orcid":"https://orcid.org/0000-0002-5757-1109","observed_orcids":["https://orcid.org/0000-0002-5757-1109"]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Shinya Toyokuni","raw_affiliation_strings":["Department of Pathology and Biology of Diseases, Graduate School of Medicine, Kyoto University, Kyoto, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology and Biology of Diseases, Graduate School of Medicine, Kyoto University, Kyoto, Japan","institution_ids":["https://openalex.org/I22299242"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109094023","display_name":"Hiroshi Hiai","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hiroshi Hiai","raw_affiliation_strings":["Department of Pathology and Biology of Diseases, Graduate School of Medicine, Kyoto University, Kyoto, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology and Biology of Diseases, Graduate School of Medicine, Kyoto University, Kyoto, Japan","institution_ids":["https://openalex.org/I22299242"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5105180840","display_name":"Wataru Mizunoya","orcid":"https://orcid.org/0000-0002-2258-1964","observed_orcids":["https://orcid.org/0000-0002-2258-1964"]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Wataru Mizunoya","raw_affiliation_strings":["Division of Food Sciences and Biotechnology, Graduate School of Agriculture, Kyoto University, Kyoto, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Food Sciences and Biotechnology, Graduate School of Agriculture, Kyoto University, Kyoto, Japan","institution_ids":["https://openalex.org/I22299242"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108206484","display_name":"Tohru Fushiki","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Tohru Fushiki","raw_affiliation_strings":["Division of Food Sciences and Biotechnology, Graduate School of Agriculture, Kyoto University, Kyoto, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Food Sciences and Biotechnology, Graduate School of Agriculture, Kyoto University, Kyoto, Japan","institution_ids":["https://openalex.org/I22299242"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085434984","display_name":"Jens Juul Holst","orcid":"https://orcid.org/0000-0001-6853-3805","observed_orcids":["https://orcid.org/0000-0001-6853-3805"]},"institutions":[{"id":"https://openalex.org/I124055696","display_name":"University of Copenhagen","ror":"https://ror.org/035b05819","country_code":"DK","type":"education","lineage":["https://openalex.org/I124055696"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Jens Juul Holst","raw_affiliation_strings":["Department of Medical Physiology, The Panum Institute, University of Copenhagen, Copenhagen, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Physiology, The Panum Institute, University of Copenhagen, Copenhagen, Denmark","institution_ids":["https://openalex.org/I124055696"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029389116","display_name":"Mitsuhiro Makino","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405270935","display_name":"Sanwa Kagaku Kenkyusho Co., Ltd. (Japan)","ror":"https://ror.org/01jrk5n74","country_code":"JP","type":"company","lineage":["https://openalex.org/I4405270935"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Mitsuhiro Makino","raw_affiliation_strings":["Sanwa Kagaku Kenkyusho Co. Ltd., Inabe, Mie, Japan","Sanwa Kagaku Kenkyusho Co. Ltd., Inabe, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sanwa Kagaku Kenkyusho Co. Ltd., Inabe, Mie, Japan","institution_ids":["https://openalex.org/I4405270935"]},{"raw_affiliation_string":"Sanwa Kagaku Kenkyusho Co. Ltd., Inabe, Japan","institution_ids":["https://openalex.org/I4405270935"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081382790","display_name":"Akira Tashita","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405270935","display_name":"Sanwa Kagaku Kenkyusho Co., Ltd. (Japan)","ror":"https://ror.org/01jrk5n74","country_code":"JP","type":"company","lineage":["https://openalex.org/I4405270935"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Akira Tashita","raw_affiliation_strings":["Sanwa Kagaku Kenkyusho Co. Ltd., Inabe, Mie, Japan","Sanwa Kagaku Kenkyusho Co. Ltd., Inabe, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sanwa Kagaku Kenkyusho Co. Ltd., Inabe, Mie, Japan","institution_ids":["https://openalex.org/I4405270935"]},{"raw_affiliation_string":"Sanwa Kagaku Kenkyusho Co. Ltd., Inabe, Japan","institution_ids":["https://openalex.org/I4405270935"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087992821","display_name":"Yukari Kobara","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405270935","display_name":"Sanwa Kagaku Kenkyusho Co., Ltd. (Japan)","ror":"https://ror.org/01jrk5n74","country_code":"JP","type":"company","lineage":["https://openalex.org/I4405270935"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yukari Kobara","raw_affiliation_strings":["Sanwa Kagaku Kenkyusho Co. Ltd., Inabe, Mie, Japan","Sanwa Kagaku Kenkyusho Co. Ltd., Inabe, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sanwa Kagaku Kenkyusho Co. Ltd., Inabe, Mie, Japan","institution_ids":["https://openalex.org/I4405270935"]},{"raw_affiliation_string":"Sanwa Kagaku Kenkyusho Co. Ltd., Inabe, Japan","institution_ids":["https://openalex.org/I4405270935"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067978512","display_name":"Yoshiharu Tsubamoto","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405270935","display_name":"Sanwa Kagaku Kenkyusho Co., Ltd. (Japan)","ror":"https://ror.org/01jrk5n74","country_code":"JP","type":"company","lineage":["https://openalex.org/I4405270935"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yoshiharu Tsubamoto","raw_affiliation_strings":["Sanwa Kagaku Kenkyusho Co. Ltd., Inabe, Mie, Japan","Sanwa Kagaku Kenkyusho Co. Ltd., Inabe, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sanwa Kagaku Kenkyusho Co. Ltd., Inabe, Mie, Japan","institution_ids":["https://openalex.org/I4405270935"]},{"raw_affiliation_string":"Sanwa Kagaku Kenkyusho Co. Ltd., Inabe, Japan","institution_ids":["https://openalex.org/I4405270935"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013680726","display_name":"Takayoshi Jinnouchi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405270935","display_name":"Sanwa Kagaku Kenkyusho Co., Ltd. (Japan)","ror":"https://ror.org/01jrk5n74","country_code":"JP","type":"company","lineage":["https://openalex.org/I4405270935"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Takayoshi Jinnouchi","raw_affiliation_strings":["Sanwa Kagaku Kenkyusho Co. Ltd., Inabe, Mie, Japan","Sanwa Kagaku Kenkyusho Co. Ltd., Inabe, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sanwa Kagaku Kenkyusho Co. Ltd., Inabe, Mie, Japan","institution_ids":["https://openalex.org/I4405270935"]},{"raw_affiliation_string":"Sanwa Kagaku Kenkyusho Co. Ltd., Inabe, Japan","institution_ids":["https://openalex.org/I4405270935"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008659249","display_name":"Takahito Jomori","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405270935","display_name":"Sanwa Kagaku Kenkyusho Co., Ltd. (Japan)","ror":"https://ror.org/01jrk5n74","country_code":"JP","type":"company","lineage":["https://openalex.org/I4405270935"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Takahito Jomori","raw_affiliation_strings":["Sanwa Kagaku Kenkyusho Co. Ltd., Inabe, Mie, Japan","Sanwa Kagaku Kenkyusho Co. Ltd., Inabe, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sanwa Kagaku Kenkyusho Co. Ltd., Inabe, Mie, Japan","institution_ids":["https://openalex.org/I4405270935"]},{"raw_affiliation_string":"Sanwa Kagaku Kenkyusho Co. Ltd., Inabe, Japan","institution_ids":["https://openalex.org/I4405270935"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5052412166","display_name":"Yutaka Seino","orcid":"https://orcid.org/0000-0002-1099-7989","observed_orcids":["https://orcid.org/0000-0002-1099-7989"]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Yutaka Seino","raw_affiliation_strings":["Department of Diabetes and Clinical Nutrition, Graduate School of Medicine, Kyoto University, Kyoto, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Diabetes and Clinical Nutrition, Graduate School of Medicine, Kyoto University, Kyoto, Japan","institution_ids":["https://openalex.org/I22299242"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5052412166"],"corresponding_institution_ids":["https://openalex.org/I22299242"],"apc_list":{"value":12690,"currency":"USD","value_usd":12690},"apc_paid":null,"fwci":7.7256,"has_fulltext":false,"cited_by_count":977,"citation_normalized_percentile":{"value":0.98370672,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"8","issue":"7","first_page":"738","last_page":"742"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10489","display_name":"Regulation of Appetite and Obesity","score":0.9580000042915344,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10489","display_name":"Regulation of Appetite and Obesity","score":0.9580000042915344,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10528","display_name":"Adipokines, Inflammation, and Metabolic Diseases","score":0.04019999876618385,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10401","display_name":"Diabetes Treatment and Management","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/glucose-dependent-insulinotropic-polypeptide","display_name":"glucose-dependent insulinotropic polypeptide","score":1.0},{"id":"https://openalex.org/keywords/gip-receptor","display_name":"GIP receptor","score":0.9290000200271606},{"id":"https://openalex.org/keywords/obesity","display_name":"obesity","score":0.9470000267028809},{"id":"https://openalex.org/keywords/insulin-resistance","display_name":"insulin resistance","score":0.9539999961853027},{"id":"https://openalex.org/keywords/high-fat-diet","display_name":"high-fat diet","score":0.9340000152587891},{"id":"https://openalex.org/keywords/adiposity","display_name":"adiposity","score":0.593999981880188},{"id":"https://openalex.org/keywords/respiratory-quotient","display_name":"respiratory quotient","score":0.8019999861717224},{"id":"https://openalex.org/keywords/fat-oxidation","display_name":"fat oxidation","score":0.6909999847412109},{"id":"https://openalex.org/keywords/anti-obesity-drugs","display_name":"anti-obesity drugs","score":0.7319999933242798},{"id":"https://openalex.org/keywords/overnutrition","display_name":"overnutrition","score":0.5540000200271606}],"concepts":[{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.8371519446372986},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.8223850727081299},{"id":"https://openalex.org/C2776129832","wikidata":"https://www.wikidata.org/wiki/Q22677256","display_name":"Gastric inhibitory polypeptide","level":4,"score":0.7763400673866272},{"id":"https://openalex.org/C511355011","wikidata":"https://www.wikidata.org/wiki/Q12174","display_name":"Obesity","level":2,"score":0.671337366104126},{"id":"https://openalex.org/C2778302649","wikidata":"https://www.wikidata.org/wiki/Q16956975","display_name":"Overnutrition","level":3,"score":0.6075019240379333},{"id":"https://openalex.org/C2777391703","wikidata":"https://www.wikidata.org/wiki/Q1053470","display_name":"Insulin resistance","level":3,"score":0.5346984267234802},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.41071265935897827},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.41011983156204224},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3705053925514221},{"id":"https://openalex.org/C2778563252","wikidata":"https://www.wikidata.org/wiki/Q170617","display_name":"Glucagon","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D000273","descriptor_name":"Adipose Tissue","qualifier_ui":"Q000033","qualifier_name":"anatomy & histology","is_major_topic":false},{"descriptor_ui":"D000273","descriptor_name":"Adipose Tissue","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001835","descriptor_name":"Body Weight","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003433","descriptor_name":"Crosses, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004041","descriptor_name":"Dietary Fats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005749","descriptor_name":"Gastric Inhibitory Polypeptide","qualifier_ui":"Q000172","qualifier_name":"deficiency","is_major_topic":false},{"descriptor_ui":"D005749","descriptor_name":"Gastric Inhibitory Polypeptide","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D005749","descriptor_name":"Gastric Inhibitory Polypeptide","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D011964","descriptor_name":"Receptors, Gastrointestinal Hormone","qualifier_ui":"Q000172","qualifier_name":"deficiency","is_major_topic":false},{"descriptor_ui":"D011964","descriptor_name":"Receptors, Gastrointestinal Hormone","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D011964","descriptor_name":"Receptors, Gastrointestinal Hormone","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D018345","descriptor_name":"Mice, Knockout","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1038/nm727","doi":"https://doi.org/10.1038/nm727","is_oa":false,"landing_page_url":"https://doi.org/10.1038/nm727","pdf_url":null,"source":{"id":"https://openalex.org/S203256638","display_name":"Nature Medicine","issn_l":"1078-8956","issn":["1078-8956","1546-170X","1744-7933"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Medicine","raw_type":"journal-article"},{"id":"pmid:12068290","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12068290","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature medicine","raw_type":"Journal Article"},{"id":"pmh:oai:pure.atira.dk:openaire_cris_publications/836d9dd0-ab52-11dd-b5e9-000ea68e967b","doi":null,"is_oa":false,"landing_page_url":"https://researchprofiles.ku.dk/da/publications/836d9dd0-ab52-11dd-b5e9-000ea68e967b","pdf_url":null,"source":{"id":"https://openalex.org/S4306401983","display_name":"Research at the University of Copenhagen (University of Copenhagen)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I124055696","host_organization_name":"University of Copenhagen","host_organization_lineage":["https://openalex.org/I124055696"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Miyawaki, K, Yamada, Y, Ban, N, Ihara, Y, Tsukiyama, K, Zhou, H, Fujimoto, S, Oku, A, Tsuda, K, Toyokuni, S, Hiai, H, Mizunoya, W, Fushiki, T, Holst, J J, Makino, M, Tashita, A, Kobara, Y, Tsubamoto, Y, Jinnouchi, T, Jomori, T & Seino, Y 2002, 'Inhibition of gastric inhibitory polypeptide signaling prevents obesity.', Nature Medicine, vol. 8, no. 7, pp. 738-42. https://doi.org/10.1038/nm727","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9537000060081482}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":24,"referenced_works":["https://openalex.org/W235051452","https://openalex.org/W1541471661","https://openalex.org/W1675830194","https://openalex.org/W1949014864","https://openalex.org/W1977053079","https://openalex.org/W1996713062","https://openalex.org/W2002134707","https://openalex.org/W2005365194","https://openalex.org/W2014093920","https://openalex.org/W2034810986","https://openalex.org/W2039481955","https://openalex.org/W2067096633","https://openalex.org/W2071692398","https://openalex.org/W2084542989","https://openalex.org/W2087133453","https://openalex.org/W2098061260","https://openalex.org/W2115778460","https://openalex.org/W2117219849","https://openalex.org/W2126918525","https://openalex.org/W2128232805","https://openalex.org/W2128979121","https://openalex.org/W2334337188","https://openalex.org/W2404123058","https://openalex.org/W2406835823"],"related_works":["https://openalex.org/W2427293651","https://openalex.org/W2384165497","https://openalex.org/W2135092079","https://openalex.org/W2572193151","https://openalex.org/W2137728524","https://openalex.org/W2037741963","https://openalex.org/W2989467600","https://openalex.org/W2132198562","https://openalex.org/W2167327445","https://openalex.org/W4407574462"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":41},{"year":2025,"cited_by_count":49},{"year":2024,"cited_by_count":62},{"year":2023,"cited_by_count":48},{"year":2022,"cited_by_count":39},{"year":2021,"cited_by_count":40},{"year":2020,"cited_by_count":38},{"year":2019,"cited_by_count":63},{"year":2018,"cited_by_count":38},{"year":2017,"cited_by_count":44},{"year":2016,"cited_by_count":39},{"year":2015,"cited_by_count":40},{"year":2014,"cited_by_count":44},{"year":2013,"cited_by_count":38},{"year":2012,"cited_by_count":39}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}