{"id":"https://openalex.org/W2102126594","doi":null,"title":"Immune selection of tumor cell variants in chickens bearing tumors induced by avian sarcoma virus.","display_name":"Immune selection of tumor cell variants in chickens bearing tumors induced by avian sarcoma virus.","publication_year":1982,"publication_date":"1982-05-01","ids":{"openalex":"https://openalex.org/W2102126594","mag":"2102126594","pmid":"https://pubmed.ncbi.nlm.nih.gov/6279281"},"language":"en","primary_location":{"id":"pmid:6279281","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/6279281","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer research","raw_type":"Journal Article"},"volume":null,"type":"article","indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5029881635","display_name":"Mark A. Wainberg","orcid":"https://orcid.org/0000-0002-0272-1317","observed_orcids":["https://orcid.org/0000-0002-0272-1317"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M A Wainberg","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110195390","display_name":"Evelyne Isra\u00ebl","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"E Israel","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":null,"display_name":"M Yu","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M Yu","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.913,"has_fulltext":false,"cited_by_count":13,"citation_normalized_percentile":{"value":0.73790952,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"42","issue":"5","first_page":"1669","last_page":"75"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12159","display_name":"T-cell and Retrovirus Studies","score":0.3955000042915344,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12159","display_name":"T-cell and Retrovirus Studies","score":0.3955000042915344,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10580","display_name":"Immunotherapy and Immune Responses","score":0.2451999932527542,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.13449999690055847,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/avian-sarcoma-virus","display_name":"avian sarcoma virus","score":0.906000018119812},{"id":"https://openalex.org/keywords/chicken-tumors","display_name":"chicken tumors","score":0.6209999918937683},{"id":"https://openalex.org/keywords/tumor-regression","display_name":"tumor regression","score":0.6190000176429749},{"id":"https://openalex.org/keywords/cell-mediated-immunity","display_name":"cell-mediated immunity","score":0.765999972820282},{"id":"https://openalex.org/keywords/virus-production","display_name":"virus production","score":0.3319999873638153},{"id":"https://openalex.org/keywords/viral-envelope-glycoprotein","display_name":"viral envelope glycoprotein","score":0.6830000281333923},{"id":"https://openalex.org/keywords/antigen-specific-lymphocytes","display_name":"antigen-specific lymphocytes","score":0.5910000205039978},{"id":"https://openalex.org/keywords/tumor-cell-killing","display_name":"tumor cell killing","score":0.625},{"id":"https://openalex.org/keywords/lymphocyte-stimulation","display_name":"lymphocyte stimulation","score":0.5839999914169312},{"id":"https://openalex.org/keywords/tumor-antigens","display_name":"tumor antigens","score":0.4909999966621399}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7715494632720947},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.6742861270904541},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.6718831658363342},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.6343555450439453},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.5284861326217651},{"id":"https://openalex.org/C2778256501","wikidata":"https://www.wikidata.org/wiki/Q223911","display_name":"Sarcoma","level":2,"score":0.5109519362449646},{"id":"https://openalex.org/C2909062048","wikidata":"https://www.wikidata.org/wiki/Q604261","display_name":"Tumor Virus","level":4,"score":0.4865242838859558},{"id":"https://openalex.org/C2776662205","wikidata":"https://www.wikidata.org/wiki/Q2459684","display_name":"Tumor antigen","level":4,"score":0.4652451276779175},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.3785977363586426},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.3591073155403137},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3419581651687622},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.2368766963481903},{"id":"https://openalex.org/C2777701055","wikidata":"https://www.wikidata.org/wiki/Q1427096","display_name":"Immunotherapy","level":3,"score":0.17352908849716187},{"id":"https://openalex.org/C29537977","wikidata":"https://www.wikidata.org/wiki/Q188941","display_name":"Cell cycle","level":3,"score":0.13223153352737427},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.09903639554977417},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000951","descriptor_name":"Antigens, Neoplasm","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D000956","descriptor_name":"Antigens, Viral","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D001358","descriptor_name":"Avian Sarcoma Viruses","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":false},{"descriptor_ui":"D002472","descriptor_name":"Cell Transformation, Viral","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002478","descriptor_name":"Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002645","descriptor_name":"Chickens","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006023","descriptor_name":"Glycoproteins","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D007111","descriptor_name":"Immunity, Cellular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008214","descriptor_name":"Lymphocytes","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D008565","descriptor_name":"Membrane Proteins","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D012509","descriptor_name":"Sarcoma","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D012509","descriptor_name":"Sarcoma","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D012509","descriptor_name":"Sarcoma","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D012513","descriptor_name":"Sarcoma, Experimental","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D014764","descriptor_name":"Viral Proteins","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D014775","descriptor_name":"Virus Activation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:6279281","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/6279281","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer research","raw_type":"Journal Article"},{"id":"mag:2102126594","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/6279281","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.8371999859809875}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":21,"referenced_works":["https://openalex.org/W1489124177","https://openalex.org/W1551508153","https://openalex.org/W1902145907","https://openalex.org/W1916484456","https://openalex.org/W1926893940","https://openalex.org/W1959066261","https://openalex.org/W1999778948","https://openalex.org/W2004605747","https://openalex.org/W2005290395","https://openalex.org/W2021038189","https://openalex.org/W2023512367","https://openalex.org/W2035348604","https://openalex.org/W2047070443","https://openalex.org/W2060478481","https://openalex.org/W2064529356","https://openalex.org/W2080732992","https://openalex.org/W2121002644","https://openalex.org/W2132960681","https://openalex.org/W2141997970","https://openalex.org/W2273249776","https://openalex.org/W2330133857"],"related_works":["https://openalex.org/W7100012939","https://openalex.org/W7098009281","https://openalex.org/W1582864470","https://openalex.org/W2005676590","https://openalex.org/W1516868449","https://openalex.org/W1489124177","https://openalex.org/W1600074110","https://openalex.org/W2090585694","https://openalex.org/W2954873960","https://openalex.org/W2411849015"],"abstract_inverted_index":{"We":[0],"have":[1,76],"compared":[2],"avian":[3,46],"sarcoma":[4,47],"cells,":[5,141],"cultured":[6],"from":[7,79,105,131,183],"tumors":[8,43,107],"at":[9,134,151],"various":[10],"stages":[11,154],"of":[12,16,35,53,99,137,146,155,219],"growth,":[13],"in":[14,40,170,201],"terms":[15],"their":[17],"ability":[18],"to":[19,25,86,92,113,190],"synthesize":[20,87,122],"infectious":[21,88],"progeny":[22,89,220],"virus":[23,90,148],"and":[24,59,91,120,161],"express":[26,110],"antigens":[27,112],"that":[28,68,83,143,195],"are":[29,84,149,165,199,204,216],"reactive":[30],"with":[31,95],"the":[32,96,114,132,152],"sensitized":[33,97],"lymphocytes":[34,98],"tumor-bearing":[36,100],"hosts.":[37,101],"Cell-mediated":[38],"immunity":[39],"chickens":[41],"bearing":[42],"induced":[44],"by":[45,51,174,207],"viruses":[48],"was":[49],"monitored":[50],"each":[52],"a":[54,208],"target":[55],"cell":[56],"cytotoxicity":[57],"test":[58],"an":[60],"antigen-driven":[61],"lymphocyte":[62],"stimulation":[63],"assay.":[64],"Our":[65],"results":[66,193],"show":[67],"it":[69],"is":[70],"only":[71],"those":[72],"tumor":[73,140,156,163,181,196],"cells":[74,104,160,164,182,197,214],"which":[75,198,215],"been":[77],"derived":[78,130],"progressively":[80,138],"growing":[81,139],"neoplasms":[82,185,203],"able":[85],"specifically":[93],"interact":[94],"In":[102],"contrast,":[103],"regressing":[106,162,202],"do":[108,118],"not":[109],"relevant":[111],"same":[115],"extent":[116],"as":[117],"progressors,":[119],"they":[121],"noninfectious":[123],"particles":[124],"only.":[125],"Experiments":[126],"on":[127],"cellular":[128],"outgrowths,":[129],"plating":[133],"limited":[135],"dilution":[136],"revealed":[142],"such":[144],"producers":[145,218],"defective":[147],"present":[150],"earliest":[153],"growth.":[157],"Both":[158],"these":[159],"poorly":[166],"stained":[167],"(about":[168,188],"10%)":[169],"indirect":[171],"immunofluorescence":[172],"tests":[173],"antiserum":[175],"against":[176,213],"viral":[177],"envelope":[178],"glycoprotein,":[179],"whereas":[180],"progressing":[184],"react":[186],"well":[187],"60":[189],"85%).":[191],"These":[192],"suggest":[194],"found":[200],"selected":[205],"out":[206],"functional":[209],"immune":[210],"response":[211],"directed":[212],"efficient":[217],"virus.":[221]},"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}