{"id":"https://openalex.org/W2101867136","doi":"https://doi.org/10.1111/j.1749-6632.1990.tb24301.x","title":"The Dominant Control Region of the Human \u03b2\u2010Globin Domain","display_name":"The Dominant Control Region of the Human \u03b2\u2010Globin Domain","publication_year":1990,"publication_date":"1990-12-01","ids":{"openalex":"https://openalex.org/W2101867136","doi":"https://doi.org/10.1111/j.1749-6632.1990.tb24301.x","mag":"2101867136","pmid":"https://pubmed.ncbi.nlm.nih.gov/2291544"},"language":"en","primary_location":{"id":"doi:10.1111/j.1749-6632.1990.tb24301.x","doi":"https://doi.org/10.1111/j.1749-6632.1990.tb24301.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1749-6632.1990.tb24301.x","pdf_url":null,"source":{"id":"https://openalex.org/S8802318","display_name":"Annals of the New York Academy of Sciences","issn_l":"0077-8923","issn":["0077-8923","1749-6632"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of the New York Academy of Sciences","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5056347519","display_name":"Frank G. Grosveld","orcid":"https://orcid.org/0000-0002-7051-4715","observed_orcids":["https://orcid.org/0000-0002-7051-4715"]},"institutions":[{"id":"https://openalex.org/I4405285715","display_name":"National Institute for Medical Research","ror":"https://ror.org/00146rb91","country_code":"GB","type":"facility","lineage":["https://openalex.org/I2801081054","https://openalex.org/I4210087105","https://openalex.org/I4405285715","https://openalex.org/I90344618"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"F. GROSVELD","raw_affiliation_strings":["Laboratory of Gene Structure and Expression, National Institute for Medical Research, Mill Hill, London, United Kingdom","Laboratory of Gene Structure and Expression National Institute for Medical Research The Ridgeway, Mill Hill London NW7 1AA United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Gene Structure and Expression, National Institute for Medical Research, Mill Hill, London, United Kingdom","institution_ids":["https://openalex.org/I4405285715"]},{"raw_affiliation_string":"Laboratory of Gene Structure and Expression National Institute for Medical Research The Ridgeway, Mill Hill London NW7 1AA United Kingdom","institution_ids":["https://openalex.org/I4405285715"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064842155","display_name":"David R. Greaves","orcid":"https://orcid.org/0000-0003-2856-9410","observed_orcids":["https://orcid.org/0000-0003-2856-9410"]},"institutions":[{"id":"https://openalex.org/I4405285715","display_name":"National Institute for Medical Research","ror":"https://ror.org/00146rb91","country_code":"GB","type":"facility","lineage":["https://openalex.org/I2801081054","https://openalex.org/I4210087105","https://openalex.org/I4405285715","https://openalex.org/I90344618"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"D. GREAVES","raw_affiliation_strings":["Laboratory of Gene Structure and Expression National Institute for Medical Research The Ridgeway, Mill Hill London NW7 1AA United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Gene Structure and Expression National Institute for Medical Research The Ridgeway, Mill Hill London NW7 1AA United Kingdom","institution_ids":["https://openalex.org/I4405285715"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069366964","display_name":"Sjaak Philipsen","orcid":"https://orcid.org/0000-0002-3690-1201","observed_orcids":["https://orcid.org/0000-0002-3690-1201"]},"institutions":[{"id":"https://openalex.org/I4405285715","display_name":"National Institute for Medical Research","ror":"https://ror.org/00146rb91","country_code":"GB","type":"facility","lineage":["https://openalex.org/I2801081054","https://openalex.org/I4210087105","https://openalex.org/I4405285715","https://openalex.org/I90344618"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"S. PHILIPSEN","raw_affiliation_strings":["Laboratory of Gene Structure and Expression National Institute for Medical Research The Ridgeway, Mill Hill London NW7 1AA United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Gene Structure and Expression National Institute for Medical Research The Ridgeway, Mill Hill London NW7 1AA United Kingdom","institution_ids":["https://openalex.org/I4405285715"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036092824","display_name":"Dale Talbot","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405285715","display_name":"National Institute for Medical Research","ror":"https://ror.org/00146rb91","country_code":"GB","type":"facility","lineage":["https://openalex.org/I2801081054","https://openalex.org/I4210087105","https://openalex.org/I4405285715","https://openalex.org/I90344618"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"D. TALBOT","raw_affiliation_strings":["Laboratory of Gene Structure and Expression National Institute for Medical Research The Ridgeway, Mill Hill London NW7 1AA United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Gene Structure and Expression National Institute for Medical Research The Ridgeway, Mill Hill London NW7 1AA United Kingdom","institution_ids":["https://openalex.org/I4405285715"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111582009","display_name":"S. Pruzina","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405285715","display_name":"National Institute for Medical Research","ror":"https://ror.org/00146rb91","country_code":"GB","type":"facility","lineage":["https://openalex.org/I2801081054","https://openalex.org/I4210087105","https://openalex.org/I4405285715","https://openalex.org/I90344618"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"S. PRUZINA","raw_affiliation_strings":["Laboratory of Gene Structure and Expression National Institute for Medical Research The Ridgeway, Mill Hill London NW7 1AA United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Gene Structure and Expression National Institute for Medical Research The Ridgeway, Mill Hill London NW7 1AA United Kingdom","institution_ids":["https://openalex.org/I4405285715"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109905999","display_name":"E. deBoer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405285715","display_name":"National Institute for Medical Research","ror":"https://ror.org/00146rb91","country_code":"GB","type":"facility","lineage":["https://openalex.org/I2801081054","https://openalex.org/I4210087105","https://openalex.org/I4405285715","https://openalex.org/I90344618"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"E. DeBOER","raw_affiliation_strings":["Laboratory of Gene Structure and Expression National Institute for Medical Research The Ridgeway, Mill Hill London NW7 1AA United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Gene Structure and Expression National Institute for Medical Research The Ridgeway, Mill Hill London NW7 1AA United Kingdom","institution_ids":["https://openalex.org/I4405285715"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010795982","display_name":"Olivia Hanscombe","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405285715","display_name":"National Institute for Medical Research","ror":"https://ror.org/00146rb91","country_code":"GB","type":"facility","lineage":["https://openalex.org/I2801081054","https://openalex.org/I4210087105","https://openalex.org/I4405285715","https://openalex.org/I90344618"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"O. HANSCOMBE","raw_affiliation_strings":["Laboratory of Gene Structure and Expression National Institute for Medical Research The Ridgeway, Mill Hill London NW7 1AA United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Gene Structure and Expression National Institute for Medical Research The Ridgeway, Mill Hill London NW7 1AA United Kingdom","institution_ids":["https://openalex.org/I4405285715"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006331835","display_name":"Pierre Belhumeur","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405285715","display_name":"National Institute for Medical Research","ror":"https://ror.org/00146rb91","country_code":"GB","type":"facility","lineage":["https://openalex.org/I2801081054","https://openalex.org/I4210087105","https://openalex.org/I4405285715","https://openalex.org/I90344618"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"P. BELHUMEUR","raw_affiliation_strings":["Laboratory of Gene Structure and Expression National Institute for Medical Research The Ridgeway, Mill Hill London NW7 1AA United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Gene Structure and Expression National Institute for Medical Research The Ridgeway, Mill Hill London NW7 1AA United Kingdom","institution_ids":["https://openalex.org/I4405285715"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113658867","display_name":"Jacky Hurst","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405285715","display_name":"National Institute for Medical Research","ror":"https://ror.org/00146rb91","country_code":"GB","type":"facility","lineage":["https://openalex.org/I2801081054","https://openalex.org/I4210087105","https://openalex.org/I4405285715","https://openalex.org/I90344618"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"J. HURST","raw_affiliation_strings":["Laboratory of Gene Structure and Expression National Institute for Medical Research The Ridgeway, Mill Hill London NW7 1AA United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Gene Structure and Expression National Institute for Medical Research The Ridgeway, Mill Hill London NW7 1AA United Kingdom","institution_ids":["https://openalex.org/I4405285715"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049273208","display_name":"Peter Fraser","orcid":"https://orcid.org/0000-0002-0041-1227","observed_orcids":["https://orcid.org/0000-0002-0041-1227"]},"institutions":[{"id":"https://openalex.org/I4405285715","display_name":"National Institute for Medical Research","ror":"https://ror.org/00146rb91","country_code":"GB","type":"facility","lineage":["https://openalex.org/I2801081054","https://openalex.org/I4210087105","https://openalex.org/I4405285715","https://openalex.org/I90344618"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"P. FRASER","raw_affiliation_strings":["Laboratory of Gene Structure and Expression National Institute for Medical Research The Ridgeway, Mill Hill London NW7 1AA United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Gene Structure and Expression National Institute for Medical Research The Ridgeway, Mill Hill London NW7 1AA United Kingdom","institution_ids":["https://openalex.org/I4405285715"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015631453","display_name":"David Whyatt","orcid":"https://orcid.org/0000-0002-6905-1979","observed_orcids":["https://orcid.org/0000-0002-6905-1979"]},"institutions":[{"id":"https://openalex.org/I4405285715","display_name":"National Institute for Medical Research","ror":"https://ror.org/00146rb91","country_code":"GB","type":"facility","lineage":["https://openalex.org/I2801081054","https://openalex.org/I4210087105","https://openalex.org/I4405285715","https://openalex.org/I90344618"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"D. WHYATT","raw_affiliation_strings":["Laboratory of Gene Structure and Expression National Institute for Medical Research The Ridgeway, Mill Hill London NW7 1AA United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Gene Structure and Expression National Institute for Medical Research The Ridgeway, Mill Hill London NW7 1AA United Kingdom","institution_ids":["https://openalex.org/I4405285715"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022832176","display_name":"Michael Nicolas Antoniou","orcid":"https://orcid.org/0000-0002-3185-5314","observed_orcids":["https://orcid.org/0000-0002-3185-5314"]},"institutions":[{"id":"https://openalex.org/I4405285715","display_name":"National Institute for Medical Research","ror":"https://ror.org/00146rb91","country_code":"GB","type":"facility","lineage":["https://openalex.org/I2801081054","https://openalex.org/I4210087105","https://openalex.org/I4405285715","https://openalex.org/I90344618"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"M. ANTONIOU","raw_affiliation_strings":["Laboratory of Gene Structure and Expression National Institute for Medical Research The Ridgeway, Mill Hill London NW7 1AA United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Gene Structure and Expression National Institute for Medical Research The Ridgeway, Mill Hill London NW7 1AA United Kingdom","institution_ids":["https://openalex.org/I4405285715"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090325782","display_name":"Vincent Mignotte","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405285715","display_name":"National Institute for Medical Research","ror":"https://ror.org/00146rb91","country_code":"GB","type":"facility","lineage":["https://openalex.org/I2801081054","https://openalex.org/I4210087105","https://openalex.org/I4405285715","https://openalex.org/I90344618"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"V. MIGNOTTE","raw_affiliation_strings":["Laboratory of Gene Structure and Expression National Institute for Medical Research The Ridgeway, Mill Hill London NW7 1AA United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Gene Structure and Expression National Institute for Medical Research The Ridgeway, Mill Hill London NW7 1AA United Kingdom","institution_ids":["https://openalex.org/I4405285715"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063298415","display_name":"Niall Dillon","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405285715","display_name":"National Institute for Medical Research","ror":"https://ror.org/00146rb91","country_code":"GB","type":"facility","lineage":["https://openalex.org/I2801081054","https://openalex.org/I4210087105","https://openalex.org/I4405285715","https://openalex.org/I90344618"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"N. DILLON","raw_affiliation_strings":["Laboratory of Gene Structure and Expression National Institute for Medical Research The Ridgeway, Mill Hill London NW7 1AA United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Gene Structure and Expression National Institute for Medical Research The Ridgeway, Mill Hill London NW7 1AA United Kingdom","institution_ids":["https://openalex.org/I4405285715"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110184230","display_name":"M H Lindenbaum","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405285715","display_name":"National Institute for Medical Research","ror":"https://ror.org/00146rb91","country_code":"GB","type":"facility","lineage":["https://openalex.org/I2801081054","https://openalex.org/I4210087105","https://openalex.org/I4405285715","https://openalex.org/I90344618"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"M. LINDENBAUM","raw_affiliation_strings":["Laboratory of Gene Structure and Expression National Institute for Medical Research The Ridgeway, Mill Hill London NW7 1AA United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Gene Structure and Expression National Institute for Medical Research The Ridgeway, Mill Hill London NW7 1AA United Kingdom","institution_ids":["https://openalex.org/I4405285715"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5039349041","display_name":"John Strouboulis","orcid":"https://orcid.org/0000-0002-6133-2872","observed_orcids":["https://orcid.org/0000-0002-6133-2872"]},"institutions":[{"id":"https://openalex.org/I4405285715","display_name":"National Institute for Medical Research","ror":"https://ror.org/00146rb91","country_code":"GB","type":"facility","lineage":["https://openalex.org/I2801081054","https://openalex.org/I4210087105","https://openalex.org/I4405285715","https://openalex.org/I90344618"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"J. STROUBOULIS","raw_affiliation_strings":["Laboratory of Gene Structure and Expression National Institute for Medical Research The Ridgeway, Mill Hill London NW7 1AA United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Gene Structure and Expression National Institute for Medical Research The Ridgeway, Mill Hill London NW7 1AA United Kingdom","institution_ids":["https://openalex.org/I4405285715"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I4405285715"],"apc_list":{"value":5080,"currency":"USD","value_usd":5080},"apc_paid":null,"fwci":0.5994,"has_fulltext":false,"cited_by_count":15,"citation_normalized_percentile":{"value":0.690301,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":"612","issue":"1","first_page":"152","last_page":"159"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10554","display_name":"Hemoglobinopathies and Related Disorders","score":0.8734999895095825,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10554","display_name":"Hemoglobinopathies and Related Disorders","score":0.8734999895095825,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12094","display_name":"Hemoglobin structure and function","score":0.08730000257492065,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.009499999694526196,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/gene-expression-regulation","display_name":"gene expression regulation","score":0.5339999794960022},{"id":"https://openalex.org/keywords/hemoglobin-gene-expression","display_name":"hemoglobin gene expression","score":0.5120000243186951},{"id":"https://openalex.org/keywords/transcriptional-regulation","display_name":"transcriptional regulation","score":0.4009999930858612}],"concepts":[{"id":"https://openalex.org/C2775924081","wikidata":"https://www.wikidata.org/wiki/Q55608371","display_name":"Control (management)","level":2,"score":0.494009792804718},{"id":"https://openalex.org/C125996951","wikidata":"https://www.wikidata.org/wiki/Q412234","display_name":"Globin","level":3,"score":0.47373664379119873},{"id":"https://openalex.org/C36503486","wikidata":"https://www.wikidata.org/wiki/Q11235244","display_name":"Domain (mathematical analysis)","level":2,"score":0.42338141798973083},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.3218381106853485},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.29238569736480713},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.27773308753967285},{"id":"https://openalex.org/C2778917026","wikidata":"https://www.wikidata.org/wiki/Q43041","display_name":"Hemoglobin","level":2,"score":0.2736665606498718},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.13643872737884521},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.13012370467185974},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.06896817684173584},{"id":"https://openalex.org/C134306372","wikidata":"https://www.wikidata.org/wiki/Q7754","display_name":"Mathematical analysis","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002872","descriptor_name":"Chromosome Deletion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003850","descriptor_name":"Deoxyribonuclease I","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005799","descriptor_name":"Genes, Dominant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005810","descriptor_name":"Multigene Family","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005914","descriptor_name":"Globins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007231","descriptor_name":"Infant, Newborn","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008822","descriptor_name":"Mice, Transgenic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016133","descriptor_name":"Polymerase Chain Reaction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1111/j.1749-6632.1990.tb24301.x","doi":"https://doi.org/10.1111/j.1749-6632.1990.tb24301.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1749-6632.1990.tb24301.x","pdf_url":null,"source":{"id":"https://openalex.org/S8802318","display_name":"Annals of the New York Academy of Sciences","issn_l":"0077-8923","issn":["0077-8923","1749-6632"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of the New York Academy of Sciences","raw_type":"journal-article"},{"id":"pmid:2291544","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2291544","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of the New York Academy of Sciences","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":24,"referenced_works":["https://openalex.org/W135011187","https://openalex.org/W155598838","https://openalex.org/W1501264308","https://openalex.org/W1595583901","https://openalex.org/W1714683344","https://openalex.org/W1983844859","https://openalex.org/W1988901023","https://openalex.org/W1990208985","https://openalex.org/W2006918190","https://openalex.org/W2019257250","https://openalex.org/W2050206304","https://openalex.org/W2055643269","https://openalex.org/W2067956561","https://openalex.org/W2080670274","https://openalex.org/W2086548325","https://openalex.org/W2087652779","https://openalex.org/W2096998693","https://openalex.org/W2100726754","https://openalex.org/W2109794416","https://openalex.org/W2118299921","https://openalex.org/W2125365759","https://openalex.org/W2142342476","https://openalex.org/W2169578753","https://openalex.org/W4238353720"],"related_works":["https://openalex.org/W2414286199","https://openalex.org/W2023964221","https://openalex.org/W2401267981","https://openalex.org/W2086451819","https://openalex.org/W7008612290","https://openalex.org/W1988803837","https://openalex.org/W7025060171","https://openalex.org/W2721932189","https://openalex.org/W2469316269","https://openalex.org/W2268741726"],"abstract_inverted_index":null,"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2012,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}
